1FZFC

Crystal structure of fragment double-d from human fibrin with the peptide ligand gly-his-arg-pro-amide
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 84
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 1998-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzfC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzfC02
2JHIF 3E1IC 2HPCB 1RF0C 2J60A 2Q9IB 1JC9A 2HPCC 1RF1B 2Z4EC 2GY7A 1FICA 1FZGB 2Q9IC 4NYTA 1FZDA 2XNXB 3GHGC 1FZGC 1N73B 1FIBA 2XNXC 4EPUA 1LTJB 1N73C 1RE4B 2JHMF 2J61B 1LT9C 1FIDA 1FZBB 1RE4C 1FZBC 2JHLF 3H32B 2OYHB 1RE3B 3BVHB 3H32C 1RF1C 2J3OA 2OYHC 2J61A 1RE3C 3BVHC 3FIBA 1FZFB 1M1JB 2J3FD 2HLOB 2J1GA 2J5ZA 1FZFC 1M1JC 2HLOC 2JHHC 1LTJC 1LWUB 4R9JA 3HUSB 4R9TA 1LWUC 1Z3SA 2D39A 3HUSC 2OYIB 2J0GA 4M7FA 1N86B 2OYIC 1FZAB 4JYOX 2FIBA 1N86C 2J2PA 1FZAC 2J0YA 2J0HA 2H43B 2Z4EB 2WNPF 2J3GA 2H43C 4ZFGA 1Z3UA 2HODB 1FZCB 1FZEB 4M7HA 2FFDB 1LT9B 2HODC 1FZCC 1FZEC 2J3FA 3E1IB 4JZCA 2FFDC 1RF0B 2J64A 2JHKF 2J3UA
chains in the Genus database with same CATH superfamily
2JHIF 3E1IC 2HPCB 1RF0C 2J60A 2Q9IB 1JC9A 2HPCC 1RF1B 2Z4EC 3GHGB 2GY7A 1FICA 1FZGB 2Q9IC 4NYTA 1FZDA 2XNXB 3GHGC 1FZGC 1N73B 1FIBA 2XNXC 4EPUA 1LTJB 1N73C 1RE4B 2JHMF 2J61B 1LT9C 1FIDA 1FZBB 1RE4C 1FZBC 2JHLF 3H32B 2OYHB 1RE3B 3BVHB 3H32C 1RF1C 2J3OA 2OYHC 2J61A 1RE3C 3BVHC 3FIBA 1FZFB 1M1JB 2J3FD 2HLOB 2J1GA 2J5ZA 1FZFC 1M1JC 2HLOC 2JHHC 1LTJC 1LWUB 4R9JA 3HUSB 4R9TA 1LWUC 1Z3SA 2D39A 3HUSC 2OYIB 2J0GA 4M7FA 1N86B 2OYIC 1FZAB 4JYOX 2FIBA 1N86C 2J2PA 1FZAC 2J0YA 2J0HA 2H43B 2Z4EB 2WNPF 2J3GA 2H43C 4ZFGA 1Z3UA 2HODB 1FZCB 1FZEB 4M7HA 2FFDB 1LT9B 2HODC 1FZCC 1FZEC 2J3FA 3E1IB 4JZCA 2FFDC 1RF0B 2J64A 2JHKF 2J3UA
chains in the Genus database with same CATH topology
2JHIF 3E1IC 2HPCB 1RF0C 2J60A 2Q9IB 1JC9A 2HPCC 1RF1B 2Z4EC 2GY7A 1FICA 1FZGB 2Q9IC 4NYTA 1FZDA 2XNXB 3GHGC 1FZGC 1N73B 1FIBA 2XNXC 4EPUA 1LTJB 1N73C 1RE4B 2JHMF 2J61B 1LT9C 1FIDA 1FZBB 1RE4C 1FZBC 2JHLF 3H32B 2OYHB 1RE3B 3BVHB 3H32C 1RF1C 2J3OA 2OYHC 2J61A 1RE3C 3BVHC 3FIBA 1FZFB 1M1JB 2J3FD 2HLOB 2J1GA 2J5ZA 1FZFC 1M1JC 2HLOC 2JHHC 1LTJC 1LWUB 4R9JA 3HUSB 4R9TA 1LWUC 1Z3SA 2D39A 3HUSC 2OYIB 2J0GA 4M7FA 1N86B 2OYIC 1FZAB 4JYOX 2FIBA 1N86C 2J2PA 1FZAC 2J0YA 2J0HA 2H43B 2Z4EB 2WNPF 2J3GA 2H43C 4ZFGA 1Z3UA 2HODB 1FZCB 1FZEB 4M7HA 2FFDB 1LT9B 2HODC 1FZCC 1FZEC 2J3FA 3E1IB 4JZCA 2FFDC 1RF0B 2J64A 2JHKF 2J3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JHI F;  3E1I C;  2HPC B;  1RF0 C;  2J60 A;  2Q9I B;  1JC9 A;  2HPC C;  1RF1 B;  2Z4E C;  2GY7 A;  1FIC A;  1FZG B;  2Q9I C;  4NYT A;  1FZD A;  2XNX B;  3GHG C;  1FZG C;  1N73 B;  1FIB A;  2XNX C;  4EPU A;  1LTJ B;  1N73 C;  1RE4 B;  2JHM F;  2J61 B;  1LT9 C;  1FID A;  1FZB B;  1RE4 C;  1FZB C;  2JHL F;  3H32 B;  2OYH B;  1RE3 B;  3BVH B;  3H32 C;  1RF1 C;  2J3O A;  2OYH C;  2J61 A;  1RE3 C;  3BVH C;  3FIB A;  1FZF B;  1M1J B;  2J3F D;  2HLO B;  2J1G A;  2J5Z A;  1FZF C;  1M1J C;  2HLO C;  2JHH C;  1LTJ C;  1LWU B;  4R9J A;  3HUS B;  4R9T A;  1LWU C;  1Z3S A;  2D39 A;  3HUS C;  2OYI B;  2J0G A;  4M7F A;  1N86 B;  2OYI C;  1FZA B;  4JYO X;  2FIB A;  1N86 C;  2J2P A;  1FZA C;  2J0Y A;  2J0H A;  2H43 B;  2Z4E B;  2WNP F;  2J3G A;  2H43 C;  4ZFG A;  1Z3U A;  2HOD B;  1FZC B;  1FZE B;  4M7H A;  2FFD B;  1LT9 B;  2HOD C;  1FZC C;  1FZE C;  2J3F A;  3E1I B;  4JZC A;  2FFD C;  1RF0 B;  2J64 A;  2JHK F;  2J3U A; 
#chains in the Genus database with same CATH topology
 2JHI F;  3E1I C;  2HPC B;  1RF0 C;  2J60 A;  2Q9I B;  1JC9 A;  2HPC C;  1RF1 B;  2Z4E C;  3GHG B;  2GY7 A;  1FIC A;  1FZG B;  2Q9I C;  4NYT A;  1FZD A;  2XNX B;  3GHG C;  1FZG C;  1N73 B;  1FIB A;  2XNX C;  4EPU A;  1LTJ B;  1N73 C;  1RE4 B;  2JHM F;  2J61 B;  1LT9 C;  1FID A;  1FZB B;  1RE4 C;  1FZB C;  2JHL F;  3H32 B;  2OYH B;  1RE3 B;  3BVH B;  3H32 C;  1RF1 C;  2J3O A;  2OYH C;  2J61 A;  1RE3 C;  3BVH C;  3FIB A;  1FZF B;  1M1J B;  2J3F D;  2HLO B;  2J1G A;  2J5Z A;  1FZF C;  1M1J C;  2HLO C;  2JHH C;  1LTJ C;  1LWU B;  4R9J A;  3HUS B;  4R9T A;  1LWU C;  1Z3S A;  2D39 A;  3HUS C;  2OYI B;  2J0G A;  4M7F A;  1N86 B;  2OYI C;  1FZA B;  4JYO X;  2FIB A;  1N86 C;  2J2P A;  1FZA C;  2J0Y A;  2J0H A;  2H43 B;  2Z4E B;  2WNP F;  2J3G A;  2H43 C;  4ZFG A;  1Z3U A;  2HOD B;  1FZC B;  1FZE B;  4M7H A;  2FFD B;  1LT9 B;  2HOD C;  1FZC C;  1FZE C;  2J3F A;  3E1I B;  4JZC A;  2FFD C;  1RF0 B;  2J64 A;  2JHK F;  2J3U A; 
#chains in the Genus database with same CATH homology
 2JHI F;  3E1I C;  2HPC B;  1RF0 C;  2J60 A;  2Q9I B;  1JC9 A;  2HPC C;  1RF1 B;  2Z4E C;  2GY7 A;  1FIC A;  1FZG B;  2Q9I C;  4NYT A;  1FZD A;  2XNX B;  3GHG C;  1FZG C;  1N73 B;  1FIB A;  2XNX C;  4EPU A;  1LTJ B;  1N73 C;  1RE4 B;  2JHM F;  2J61 B;  1LT9 C;  1FID A;  1FZB B;  1RE4 C;  1FZB C;  2JHL F;  3H32 B;  2OYH B;  1RE3 B;  3BVH B;  3H32 C;  1RF1 C;  2J3O A;  2OYH C;  2J61 A;  1RE3 C;  3BVH C;  3FIB A;  1FZF B;  1M1J B;  2J3F D;  2HLO B;  2J1G A;  2J5Z A;  1FZF C;  1M1J C;  2HLO C;  2JHH C;  1LTJ C;  1LWU B;  4R9J A;  3HUS B;  4R9T A;  1LWU C;  1Z3S A;  2D39 A;  3HUS C;  2OYI B;  2J0G A;  4M7F A;  1N86 B;  2OYI C;  1FZA B;  4JYO X;  2FIB A;  1N86 C;  2J2P A;  1FZA C;  2J0Y A;  2J0H A;  2H43 B;  2Z4E B;  2WNP F;  2J3G A;  2H43 C;  4ZFG A;  1Z3U A;  2HOD B;  1FZC B;  1FZE B;  4M7H A;  2FFD B;  1LT9 B;  2HOD C;  1FZC C;  1FZE C;  2J3F A;  3E1I B;  4JZC A;  2FFD C;  1RF0 B;  2J64 A;  2JHK F;  2J3U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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