1FZFC

Crystal structure of fragment double-d from human fibrin with the peptide ligand gly-his-arg-pro-amide
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 84
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 1998-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzfC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzfC02
1FZBB 1RE4B 4M7HA 1RE4C 1FIDA 2J64A 2JHKF 3GHGC 1FZGB 2JHHC 2FIBA 2JHIF 2XNXB 2XNXC 4ZFGA 2D39A 2J0HA 2WNPF 1Z3SA 2J61B 1LTJB 1LTJC 2J0GA 4JZCA 4JYOX 1FZDA 1RF1B 2J2PA 1RF1C 2J3UA 2J3GA 1FIBA 1RF0B 1RF0C 4NYTA 1N86B 1FZEB 1N86C 1FZEC 1Z3UA 3H32B 2OYIB 2FFDC 2J0YA 3H32C 2OYIC 1FZAB 2Q9IB 1FZAC 2Q9IC 1LWUB 1LWUC 2GY7A 3BVHC 1LT9C 2J1GA 2J3FD 1FICA 2J5ZA 2J60A 1M1JB 1FZCC 1M1JC 4R9JA 2HLOB 2JHLF 2HLOC 2J61A 4M7FA 3FIBA 2HPCB 2FFDB 2HPCC 3HUSB 4EPUA 1FZBC 3HUSC 3E1IB 3E1IC 3BVHB 1LT9B 2Z4EB 2J3OA 2Z4EC 1JC9A 1RE3B 1RE3C 2J3FA 1FZCB 1FZGC 2OYHB 2OYHC 1N73B 1N73C 2H43B 2HODB 2H43C 2HODC 2JHMF 1FZFB 1FZFC 4R9TA
chains in the Genus database with same CATH superfamily
1FZBB 1RE4B 4M7HA 1RE4C 1FIDA 2J64A 2JHKF 3GHGB 3GHGC 1FZGB 2JHHC 2FIBA 2JHIF 2XNXB 2XNXC 4ZFGA 2D39A 2J0HA 2WNPF 1Z3SA 2J61B 1LTJB 1LTJC 2J0GA 4JZCA 4JYOX 1FZDA 1RF1B 2J2PA 1RF1C 2J3UA 2J3GA 1FIBA 1RF0B 1RF0C 4NYTA 1N86B 1FZEB 1N86C 1FZEC 1Z3UA 3H32B 2OYIB 2FFDC 2J0YA 3H32C 2OYIC 1FZAB 2Q9IB 1FZAC 2Q9IC 1LWUB 1LWUC 2GY7A 3BVHC 1LT9C 2J1GA 2J3FD 1FICA 2J5ZA 2J60A 1M1JB 1FZCC 1M1JC 4R9JA 2HLOB 2JHLF 2HLOC 2J61A 4M7FA 3FIBA 2HPCB 2FFDB 2HPCC 3HUSB 4EPUA 1FZBC 3HUSC 3E1IB 3E1IC 3BVHB 1LT9B 2Z4EB 2J3OA 2Z4EC 1JC9A 1RE3B 1RE3C 2J3FA 1FZCB 1FZGC 2OYHB 2OYHC 1N73B 1N73C 2H43B 2HODB 2H43C 2HODC 2JHMF 1FZFB 1FZFC 4R9TA
chains in the Genus database with same CATH topology
1FZBB 1RE4B 4M7HA 1RE4C 1FIDA 2J64A 2JHKF 3GHGC 1FZGB 2JHHC 2FIBA 2JHIF 2XNXB 2XNXC 4ZFGA 2D39A 2J0HA 2WNPF 1Z3SA 2J61B 1LTJB 1LTJC 2J0GA 4JZCA 4JYOX 1FZDA 1RF1B 2J2PA 1RF1C 2J3UA 2J3GA 1FIBA 1RF0B 1RF0C 4NYTA 1N86B 1FZEB 1N86C 1FZEC 1Z3UA 3H32B 2OYIB 2FFDC 2J0YA 3H32C 2OYIC 1FZAB 2Q9IB 1FZAC 2Q9IC 1LWUB 1LWUC 2GY7A 3BVHC 1LT9C 2J1GA 2J3FD 1FICA 2J5ZA 2J60A 1M1JB 1FZCC 1M1JC 4R9JA 2HLOB 2JHLF 2HLOC 2J61A 4M7FA 3FIBA 2HPCB 2FFDB 2HPCC 3HUSB 4EPUA 1FZBC 3HUSC 3E1IB 3E1IC 3BVHB 1LT9B 2Z4EB 2J3OA 2Z4EC 1JC9A 1RE3B 1RE3C 2J3FA 1FZCB 1FZGC 2OYHB 2OYHC 1N73B 1N73C 2H43B 2HODB 2H43C 2HODC 2JHMF 1FZFB 1FZFC 4R9TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZB B;  1RE4 B;  4M7H A;  1RE4 C;  1FID A;  2J64 A;  2JHK F;  3GHG C;  1FZG B;  2JHH C;  2FIB A;  2JHI F;  2XNX B;  2XNX C;  4ZFG A;  2D39 A;  2J0H A;  2WNP F;  1Z3S A;  2J61 B;  1LTJ B;  1LTJ C;  2J0G A;  4JZC A;  4JYO X;  1FZD A;  1RF1 B;  2J2P A;  1RF1 C;  2J3U A;  2J3G A;  1FIB A;  1RF0 B;  1RF0 C;  4NYT A;  1N86 B;  1FZE B;  1N86 C;  1FZE C;  1Z3U A;  3H32 B;  2OYI B;  2FFD C;  2J0Y A;  3H32 C;  2OYI C;  1FZA B;  2Q9I B;  1FZA C;  2Q9I C;  1LWU B;  1LWU C;  2GY7 A;  3BVH C;  1LT9 C;  2J1G A;  2J3F D;  1FIC A;  2J5Z A;  2J60 A;  1M1J B;  1FZC C;  1M1J C;  4R9J A;  2HLO B;  2JHL F;  2HLO C;  2J61 A;  4M7F A;  3FIB A;  2HPC B;  2FFD B;  2HPC C;  3HUS B;  4EPU A;  1FZB C;  3HUS C;  3E1I B;  3E1I C;  3BVH B;  1LT9 B;  2Z4E B;  2J3O A;  2Z4E C;  1JC9 A;  1RE3 B;  1RE3 C;  2J3F A;  1FZC B;  1FZG C;  2OYH B;  2OYH C;  1N73 B;  1N73 C;  2H43 B;  2HOD B;  2H43 C;  2HOD C;  2JHM F;  1FZF B;  1FZF C;  4R9T A; 
#chains in the Genus database with same CATH topology
 1FZB B;  1RE4 B;  4M7H A;  1RE4 C;  1FID A;  2J64 A;  2JHK F;  3GHG B;  3GHG C;  1FZG B;  2JHH C;  2FIB A;  2JHI F;  2XNX B;  2XNX C;  4ZFG A;  2D39 A;  2J0H A;  2WNP F;  1Z3S A;  2J61 B;  1LTJ B;  1LTJ C;  2J0G A;  4JZC A;  4JYO X;  1FZD A;  1RF1 B;  2J2P A;  1RF1 C;  2J3U A;  2J3G A;  1FIB A;  1RF0 B;  1RF0 C;  4NYT A;  1N86 B;  1FZE B;  1N86 C;  1FZE C;  1Z3U A;  3H32 B;  2OYI B;  2FFD C;  2J0Y A;  3H32 C;  2OYI C;  1FZA B;  2Q9I B;  1FZA C;  2Q9I C;  1LWU B;  1LWU C;  2GY7 A;  3BVH C;  1LT9 C;  2J1G A;  2J3F D;  1FIC A;  2J5Z A;  2J60 A;  1M1J B;  1FZC C;  1M1J C;  4R9J A;  2HLO B;  2JHL F;  2HLO C;  2J61 A;  4M7F A;  3FIB A;  2HPC B;  2FFD B;  2HPC C;  3HUS B;  4EPU A;  1FZB C;  3HUS C;  3E1I B;  3E1I C;  3BVH B;  1LT9 B;  2Z4E B;  2J3O A;  2Z4E C;  1JC9 A;  1RE3 B;  1RE3 C;  2J3F A;  1FZC B;  1FZG C;  2OYH B;  2OYH C;  1N73 B;  1N73 C;  2H43 B;  2HOD B;  2H43 C;  2HOD C;  2JHM F;  1FZF B;  1FZF C;  4R9T A; 
#chains in the Genus database with same CATH homology
 1FZB B;  1RE4 B;  4M7H A;  1RE4 C;  1FID A;  2J64 A;  2JHK F;  3GHG C;  1FZG B;  2JHH C;  2FIB A;  2JHI F;  2XNX B;  2XNX C;  4ZFG A;  2D39 A;  2J0H A;  2WNP F;  1Z3S A;  2J61 B;  1LTJ B;  1LTJ C;  2J0G A;  4JZC A;  4JYO X;  1FZD A;  1RF1 B;  2J2P A;  1RF1 C;  2J3U A;  2J3G A;  1FIB A;  1RF0 B;  1RF0 C;  4NYT A;  1N86 B;  1FZE B;  1N86 C;  1FZE C;  1Z3U A;  3H32 B;  2OYI B;  2FFD C;  2J0Y A;  3H32 C;  2OYI C;  1FZA B;  2Q9I B;  1FZA C;  2Q9I C;  1LWU B;  1LWU C;  2GY7 A;  3BVH C;  1LT9 C;  2J1G A;  2J3F D;  1FIC A;  2J5Z A;  2J60 A;  1M1J B;  1FZC C;  1M1J C;  4R9J A;  2HLO B;  2JHL F;  2HLO C;  2J61 A;  4M7F A;  3FIB A;  2HPC B;  2FFD B;  2HPC C;  3HUS B;  4EPU A;  1FZB C;  3HUS C;  3E1I B;  3E1I C;  3BVH B;  1LT9 B;  2Z4E B;  2J3O A;  2Z4E C;  1JC9 A;  1RE3 B;  1RE3 C;  2J3F A;  1FZC B;  1FZG C;  2OYH B;  2OYH C;  1N73 B;  1N73 C;  2H43 B;  2HOD B;  2H43 C;  2HOD C;  2JHM F;  1FZF B;  1FZF C;  4R9T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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