1FZGB

Crystal structure of fragment d from human fibrinogen with the peptide ligand gly-his-arg-pro-amide
Total Genus 92

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTIV3 (165-168)AH4 (296-305)TIV1 (157-160)S6 (288-289)TIV2 (159-162)AH1 (169-193)TI'1 (244-247)TVIII1 (193-196)TIV9 (280-283)AH2 (211-217)S1 (223-227)TVIII2 (228-231)S2 (236-241)S3 (249-255)TIV5 (230-233)TIV7 (243-246)TIV8 (255-258)S5 (277-278)S7 (292-293)AH3 (266-271)S4 (273-274)3H1 (162-164)TIV6 (241-244)O1 (262-264)Updating...
connected with : NaN
molecule tags Blood coagulation
publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule keywords FIBRINOGEN
total genus 92
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 1999-01-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzgB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzgB02
3HUSC 1FZEB 4NYTA 4M7FA 1RF0B 4M7HA 2H43B 3FIBA 3H32B 4JZCA 4ZFGA 2HPCC 1LT9C 2J3OA 2FIBA 2FFDB 4EPUA 1RE4B 1N73C 2JHLF 2J0YA 1RE3B 2Z4EC 2HPCB 1LT9B 2J3UA 1FZFC 2J2PA 1FZAC 1Z3UA 2HODB 1RF1B 2Z4EB 1FZGC 2OYHC 3HUSB 2Q9IC 4R9JA 3GHGC 4R9TA 1N86C 1FZGB 2OYHB 2WNPF 2J3GA 2JHMF 3BVHC 1JC9A 3E1IC 2J64A 2JHKF 1FIBA 1M1JC 1N86B 1LTJC 2J61B 1FICA 2JHIF 2OYIC 1FZBC 1N73B 2J3FD 3BVHB 1M1JB 1FZFB 1LWUC 1FZAB 1FZEC 2J61A 2J0HA 1RF0C 2D39A 1FZCC 2HLOC 4JYOX 2H43C 3H32C 2Q9IB 2J1GA 2J60A 2J0GA 2FFDC 1FIDA 1FZCB 2XNXC 1RE4C 2HLOB 1Z3SA 2J3FA 3E1IB 1RE3C 2J5ZA 1FZDA 1LTJB 2OYIB 1FZBB 2XNXB 2HODC 2GY7A 1RF1C 2JHHC 1LWUB
chains in the Genus database with same CATH superfamily
3HUSC 1FZEB 4NYTA 4M7FA 1RF0B 4M7HA 2H43B 3FIBA 3H32B 4JZCA 4ZFGA 2HPCC 1LT9C 2J3OA 2FIBA 2FFDB 4EPUA 1RE4B 1N73C 2JHLF 2J0YA 1RE3B 2Z4EC 2HPCB 1LT9B 2J3UA 1FZFC 2J2PA 1FZAC 1Z3UA 2HODB 1RF1B 2Z4EB 1FZGC 2OYHC 3HUSB 2Q9IC 4R9JA 3GHGC 4R9TA 1N86C 1FZGB 2OYHB 2WNPF 2J3GA 2JHMF 3BVHC 1JC9A 3E1IC 2J64A 2JHKF 1FIBA 1M1JC 1N86B 1LTJC 2J61B 1FICA 2JHIF 2OYIC 1FZBC 1N73B 2J3FD 3BVHB 1M1JB 1FZFB 1LWUC 1FZAB 1FZEC 2J61A 2J0HA 1RF0C 2D39A 1FZCC 2HLOC 4JYOX 2H43C 3H32C 2Q9IB 3GHGB 2J1GA 2J60A 2J0GA 2FFDC 1FIDA 1FZCB 2XNXC 1RE4C 2HLOB 1Z3SA 2J3FA 3E1IB 1RE3C 2J5ZA 1FZDA 1LTJB 2OYIB 1FZBB 2XNXB 2HODC 2GY7A 1RF1C 2JHHC 1LWUB
chains in the Genus database with same CATH topology
3HUSC 1FZEB 4NYTA 4M7FA 1RF0B 4M7HA 2H43B 3FIBA 3H32B 4JZCA 4ZFGA 2HPCC 1LT9C 2J3OA 2FIBA 2FFDB 4EPUA 1RE4B 1N73C 2JHLF 2J0YA 1RE3B 2Z4EC 2HPCB 1LT9B 2J3UA 1FZFC 2J2PA 1FZAC 1Z3UA 2HODB 1RF1B 2Z4EB 1FZGC 2OYHC 3HUSB 2Q9IC 4R9JA 3GHGC 4R9TA 1N86C 1FZGB 2OYHB 2WNPF 2J3GA 2JHMF 3BVHC 1JC9A 3E1IC 2J64A 2JHKF 1FIBA 1M1JC 1N86B 1LTJC 2J61B 1FICA 2JHIF 2OYIC 1FZBC 1N73B 2J3FD 3BVHB 1M1JB 1FZFB 1LWUC 1FZAB 1FZEC 2J61A 2J0HA 1RF0C 2D39A 1FZCC 2HLOC 4JYOX 2H43C 3H32C 2Q9IB 2J1GA 2J60A 2J0GA 2FFDC 1FIDA 1FZCB 2XNXC 1RE4C 2HLOB 1Z3SA 2J3FA 3E1IB 1RE3C 2J5ZA 1FZDA 1LTJB 2OYIB 1FZBB 2XNXB 2HODC 2GY7A 1RF1C 2JHHC 1LWUB
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3HUS C;  1FZE B;  4NYT A;  4M7F A;  1RF0 B;  4M7H A;  2H43 B;  3FIB A;  3H32 B;  4JZC A;  4ZFG A;  2HPC C;  1LT9 C;  2J3O A;  2FIB A;  2FFD B;  4EPU A;  1RE4 B;  1N73 C;  2JHL F;  2J0Y A;  1RE3 B;  2Z4E C;  2HPC B;  1LT9 B;  2J3U A;  1FZF C;  2J2P A;  1FZA C;  1Z3U A;  2HOD B;  1RF1 B;  2Z4E B;  1FZG C;  2OYH C;  3HUS B;  2Q9I C;  4R9J A;  3GHG C;  4R9T A;  1N86 C;  1FZG B;  2OYH B;  2WNP F;  2J3G A;  2JHM F;  3BVH C;  1JC9 A;  3E1I C;  2J64 A;  2JHK F;  1FIB A;  1M1J C;  1N86 B;  1LTJ C;  2J61 B;  1FIC A;  2JHI F;  2OYI C;  1FZB C;  1N73 B;  2J3F D;  3BVH B;  1M1J B;  1FZF B;  1LWU C;  1FZA B;  1FZE C;  2J61 A;  2J0H A;  1RF0 C;  2D39 A;  1FZC C;  2HLO C;  4JYO X;  2H43 C;  3H32 C;  2Q9I B;  2J1G A;  2J60 A;  2J0G A;  2FFD C;  1FID A;  1FZC B;  2XNX C;  1RE4 C;  2HLO B;  1Z3S A;  2J3F A;  3E1I B;  1RE3 C;  2J5Z A;  1FZD A;  1LTJ B;  2OYI B;  1FZB B;  2XNX B;  2HOD C;  2GY7 A;  1RF1 C;  2JHH C;  1LWU B; 
#chains in the Genus database with same CATH topology
 3HUS C;  1FZE B;  4NYT A;  4M7F A;  1RF0 B;  4M7H A;  2H43 B;  3FIB A;  3H32 B;  4JZC A;  4ZFG A;  2HPC C;  1LT9 C;  2J3O A;  2FIB A;  2FFD B;  4EPU A;  1RE4 B;  1N73 C;  2JHL F;  2J0Y A;  1RE3 B;  2Z4E C;  2HPC B;  1LT9 B;  2J3U A;  1FZF C;  2J2P A;  1FZA C;  1Z3U A;  2HOD B;  1RF1 B;  2Z4E B;  1FZG C;  2OYH C;  3HUS B;  2Q9I C;  4R9J A;  3GHG C;  4R9T A;  1N86 C;  1FZG B;  2OYH B;  2WNP F;  2J3G A;  2JHM F;  3BVH C;  1JC9 A;  3E1I C;  2J64 A;  2JHK F;  1FIB A;  1M1J C;  1N86 B;  1LTJ C;  2J61 B;  1FIC A;  2JHI F;  2OYI C;  1FZB C;  1N73 B;  2J3F D;  3BVH B;  1M1J B;  1FZF B;  1LWU C;  1FZA B;  1FZE C;  2J61 A;  2J0H A;  1RF0 C;  2D39 A;  1FZC C;  2HLO C;  4JYO X;  2H43 C;  3H32 C;  2Q9I B;  3GHG B;  2J1G A;  2J60 A;  2J0G A;  2FFD C;  1FID A;  1FZC B;  2XNX C;  1RE4 C;  2HLO B;  1Z3S A;  2J3F A;  3E1I B;  1RE3 C;  2J5Z A;  1FZD A;  1LTJ B;  2OYI B;  1FZB B;  2XNX B;  2HOD C;  2GY7 A;  1RF1 C;  2JHH C;  1LWU B; 
#chains in the Genus database with same CATH homology
 3HUS C;  1FZE B;  4NYT A;  4M7F A;  1RF0 B;  4M7H A;  2H43 B;  3FIB A;  3H32 B;  4JZC A;  4ZFG A;  2HPC C;  1LT9 C;  2J3O A;  2FIB A;  2FFD B;  4EPU A;  1RE4 B;  1N73 C;  2JHL F;  2J0Y A;  1RE3 B;  2Z4E C;  2HPC B;  1LT9 B;  2J3U A;  1FZF C;  2J2P A;  1FZA C;  1Z3U A;  2HOD B;  1RF1 B;  2Z4E B;  1FZG C;  2OYH C;  3HUS B;  2Q9I C;  4R9J A;  3GHG C;  4R9T A;  1N86 C;  1FZG B;  2OYH B;  2WNP F;  2J3G A;  2JHM F;  3BVH C;  1JC9 A;  3E1I C;  2J64 A;  2JHK F;  1FIB A;  1M1J C;  1N86 B;  1LTJ C;  2J61 B;  1FIC A;  2JHI F;  2OYI C;  1FZB C;  1N73 B;  2J3F D;  3BVH B;  1M1J B;  1FZF B;  1LWU C;  1FZA B;  1FZE C;  2J61 A;  2J0H A;  1RF0 C;  2D39 A;  1FZC C;  2HLO C;  4JYO X;  2H43 C;  3H32 C;  2Q9I B;  2J1G A;  2J60 A;  2J0G A;  2FFD C;  1FID A;  1FZC B;  2XNX C;  1RE4 C;  2HLO B;  1Z3S A;  2J3F A;  3E1I B;  1RE3 C;  2J5Z A;  1FZD A;  1LTJ B;  2OYI B;  1FZB B;  2XNX B;  2HOD C;  2GY7 A;  1RF1 C;  2JHH C;  1LWU B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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