1N86B

Crystal structure of human d-dimer from cross-linked fibrin complexed with gpr and ghrpldk peptide ligands.
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
307
structure length
307
Chain Sequence
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrin alpha/alpha-E chain
total genus 84
structure length 307
sequence length 307
chains with identical sequence E
ec nomenclature
pdb deposition date 2002-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1n86B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1n86B02
2HPCC 2FIBA 1FZCB 4JZCA 1FZGB 2J3UA 3BVHC 2Z4EC 1FIDA 1FZAC 2H43C 1FZDA 1FIBA 2J0GA 2FFDC 1N73B 4R9TA 2D39A 1LT9B 2XNXC 2J61A 1Z3SA 3E1IC 2OYHB 1FZEC 4M7FA 1LTJB 3HUSB 2OYIC 2HLOB 2HPCB 4JYOX 3FIBA 2JHHC 2JHMF 2Q9IC 4EPUA 3BVHB 2Z4EB 2JHIF 2JHKF 2GY7A 1FZAB 1RF0C 1RF1C 2H43B 3GHGC 2WNPF 2J0HA 2FFDB 1JC9A 1RE4C 1FZFC 1M1JC 2XNXB 3E1IB 1FZEB 1LWUC 2J2PA 1N86C 1RE3C 2OYIB 4ZFGA 2J1GA 2Q9IB 3H32C 2J61B 1RF0B 4NYTA 1RF1B 1FZBC 2JHLF 2J3FA 2HODC 1RE4B 1FZFB 1M1JB 1FZCC 1FZGC 4M7HA 2J3OA 1Z3UA 1LWUB 2J5ZA 1N86B 1RE3B 1FICA 2J64A 1N73C 3H32B 2J60A 1LT9C 2J3GA 2J3FD 1FZBB 2J0YA 2OYHC 1LTJC 2HODB 3HUSC 4R9JA 2HLOC
chains in the Genus database with same CATH superfamily
2HPCC 2FIBA 1FZCB 4JZCA 1FZGB 2J3UA 3BVHC 2Z4EC 1FIDA 1FZAC 2H43C 1FZDA 1FIBA 2J0GA 2FFDC 1N73B 4R9TA 2D39A 1LT9B 2XNXC 2J61A 1Z3SA 3E1IC 2OYHB 1FZEC 4M7FA 1LTJB 3HUSB 2OYIC 2HLOB 2HPCB 4JYOX 3FIBA 2JHHC 2JHMF 2Q9IC 4EPUA 3BVHB 2Z4EB 2JHIF 2JHKF 2GY7A 1FZAB 1RF0C 1RF1C 2H43B 3GHGC 2WNPF 2J0HA 2FFDB 1JC9A 1RE4C 1FZFC 1M1JC 2XNXB 3E1IB 1FZEB 1LWUC 2J2PA 1N86C 1RE3C 2OYIB 4ZFGA 2J1GA 2Q9IB 3H32C 2J61B 1RF0B 4NYTA 1RF1B 1FZBC 2JHLF 3GHGB 2J3FA 2HODC 1RE4B 1FZFB 1M1JB 1FZCC 1FZGC 4M7HA 2J3OA 1Z3UA 1LWUB 2J5ZA 1N86B 1RE3B 1FICA 2J64A 1N73C 3H32B 2J60A 1LT9C 2J3GA 2J3FD 1FZBB 2J0YA 2OYHC 1LTJC 2HODB 3HUSC 4R9JA 2HLOC
chains in the Genus database with same CATH topology
2HPCC 2FIBA 1FZCB 4JZCA 1FZGB 2J3UA 3BVHC 2Z4EC 1FIDA 1FZAC 2H43C 1FZDA 1FIBA 2J0GA 2FFDC 1N73B 4R9TA 2D39A 1LT9B 2XNXC 2J61A 1Z3SA 3E1IC 2OYHB 1FZEC 4M7FA 1LTJB 3HUSB 2OYIC 2HLOB 2HPCB 4JYOX 3FIBA 2JHHC 2JHMF 2Q9IC 4EPUA 3BVHB 2Z4EB 2JHIF 2JHKF 2GY7A 1FZAB 1RF0C 1RF1C 2H43B 3GHGC 2WNPF 2J0HA 2FFDB 1JC9A 1RE4C 1FZFC 1M1JC 2XNXB 3E1IB 1FZEB 1LWUC 2J2PA 1N86C 1RE3C 2OYIB 4ZFGA 2J1GA 2Q9IB 3H32C 2J61B 1RF0B 4NYTA 1RF1B 1FZBC 2JHLF 2J3FA 2HODC 1RE4B 1FZFB 1M1JB 1FZCC 1FZGC 4M7HA 2J3OA 1Z3UA 1LWUB 2J5ZA 1N86B 1RE3B 1FICA 2J64A 1N73C 3H32B 2J60A 1LT9C 2J3GA 2J3FD 1FZBB 2J0YA 2OYHC 1LTJC 2HODB 3HUSC 4R9JA 2HLOC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HPC C;  2FIB A;  1FZC B;  4JZC A;  1FZG B;  2J3U A;  3BVH C;  2Z4E C;  1FID A;  1FZA C;  2H43 C;  1FZD A;  1FIB A;  2J0G A;  2FFD C;  1N73 B;  4R9T A;  2D39 A;  1LT9 B;  2XNX C;  2J61 A;  1Z3S A;  3E1I C;  2OYH B;  1FZE C;  4M7F A;  1LTJ B;  3HUS B;  2OYI C;  2HLO B;  2HPC B;  4JYO X;  3FIB A;  2JHH C;  2JHM F;  2Q9I C;  4EPU A;  3BVH B;  2Z4E B;  2JHI F;  2JHK F;  2GY7 A;  1FZA B;  1RF0 C;  1RF1 C;  2H43 B;  3GHG C;  2WNP F;  2J0H A;  2FFD B;  1JC9 A;  1RE4 C;  1FZF C;  1M1J C;  2XNX B;  3E1I B;  1FZE B;  1LWU C;  2J2P A;  1N86 C;  1RE3 C;  2OYI B;  4ZFG A;  2J1G A;  2Q9I B;  3H32 C;  2J61 B;  1RF0 B;  4NYT A;  1RF1 B;  1FZB C;  2JHL F;  2J3F A;  2HOD C;  1RE4 B;  1FZF B;  1M1J B;  1FZC C;  1FZG C;  4M7H A;  2J3O A;  1Z3U A;  1LWU B;  2J5Z A;  1N86 B;  1RE3 B;  1FIC A;  2J64 A;  1N73 C;  3H32 B;  2J60 A;  1LT9 C;  2J3G A;  2J3F D;  1FZB B;  2J0Y A;  2OYH C;  1LTJ C;  2HOD B;  3HUS C;  4R9J A;  2HLO C; 
#chains in the Genus database with same CATH topology
 2HPC C;  2FIB A;  1FZC B;  4JZC A;  1FZG B;  2J3U A;  3BVH C;  2Z4E C;  1FID A;  1FZA C;  2H43 C;  1FZD A;  1FIB A;  2J0G A;  2FFD C;  1N73 B;  4R9T A;  2D39 A;  1LT9 B;  2XNX C;  2J61 A;  1Z3S A;  3E1I C;  2OYH B;  1FZE C;  4M7F A;  1LTJ B;  3HUS B;  2OYI C;  2HLO B;  2HPC B;  4JYO X;  3FIB A;  2JHH C;  2JHM F;  2Q9I C;  4EPU A;  3BVH B;  2Z4E B;  2JHI F;  2JHK F;  2GY7 A;  1FZA B;  1RF0 C;  1RF1 C;  2H43 B;  3GHG C;  2WNP F;  2J0H A;  2FFD B;  1JC9 A;  1RE4 C;  1FZF C;  1M1J C;  2XNX B;  3E1I B;  1FZE B;  1LWU C;  2J2P A;  1N86 C;  1RE3 C;  2OYI B;  4ZFG A;  2J1G A;  2Q9I B;  3H32 C;  2J61 B;  1RF0 B;  4NYT A;  1RF1 B;  1FZB C;  2JHL F;  3GHG B;  2J3F A;  2HOD C;  1RE4 B;  1FZF B;  1M1J B;  1FZC C;  1FZG C;  4M7H A;  2J3O A;  1Z3U A;  1LWU B;  2J5Z A;  1N86 B;  1RE3 B;  1FIC A;  2J64 A;  1N73 C;  3H32 B;  2J60 A;  1LT9 C;  2J3G A;  2J3F D;  1FZB B;  2J0Y A;  2OYH C;  1LTJ C;  2HOD B;  3HUS C;  4R9J A;  2HLO C; 
#chains in the Genus database with same CATH homology
 2HPC C;  2FIB A;  1FZC B;  4JZC A;  1FZG B;  2J3U A;  3BVH C;  2Z4E C;  1FID A;  1FZA C;  2H43 C;  1FZD A;  1FIB A;  2J0G A;  2FFD C;  1N73 B;  4R9T A;  2D39 A;  1LT9 B;  2XNX C;  2J61 A;  1Z3S A;  3E1I C;  2OYH B;  1FZE C;  4M7F A;  1LTJ B;  3HUS B;  2OYI C;  2HLO B;  2HPC B;  4JYO X;  3FIB A;  2JHH C;  2JHM F;  2Q9I C;  4EPU A;  3BVH B;  2Z4E B;  2JHI F;  2JHK F;  2GY7 A;  1FZA B;  1RF0 C;  1RF1 C;  2H43 B;  3GHG C;  2WNP F;  2J0H A;  2FFD B;  1JC9 A;  1RE4 C;  1FZF C;  1M1J C;  2XNX B;  3E1I B;  1FZE B;  1LWU C;  2J2P A;  1N86 C;  1RE3 C;  2OYI B;  4ZFG A;  2J1G A;  2Q9I B;  3H32 C;  2J61 B;  1RF0 B;  4NYT A;  1RF1 B;  1FZB C;  2JHL F;  2J3F A;  2HOD C;  1RE4 B;  1FZF B;  1M1J B;  1FZC C;  1FZG C;  4M7H A;  2J3O A;  1Z3U A;  1LWU B;  2J5Z A;  1N86 B;  1RE3 B;  1FIC A;  2J64 A;  1N73 C;  3H32 B;  2J60 A;  1LT9 C;  2J3G A;  2J3F D;  1FZB B;  2J0Y A;  2OYH C;  1LTJ C;  2HOD B;  3HUS C;  4R9J A;  2HLO C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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