1N86B

Crystal structure of human d-dimer from cross-linked fibrin complexed with gpr and ghrpldk peptide ligands.
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
307
structure length
307
Chain Sequence
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
publication title The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
pubmed doi rcsb
molecule keywords Fibrin alpha/alpha-E chain
total genus 84
structure length 307
sequence length 307
chains with identical sequence E
ec nomenclature
pdb deposition date 2002-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1n86B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1n86B02
3BVHC 2FFDB 2HPCB 2OYIB 2J61A 1FIDA 2Z4EC 2J5ZA 2JHMF 2WNPF 3HUSC 2J3OA 3E1IB 2J61B 1FZGB 1Z3UA 2XNXC 1LTJB 1FZBB 1RE4C 2J1GA 2JHKF 1M1JC 1RF0C 1FZDA 2H43B 1Z3SA 2JHHC 1FZFB 1JC9A 1RF1B 2D39A 2J3UA 1FZEC 2Q9IB 2HLOB 2J60A 1N86B 1N73B 4M7HA 1LWUB 2GY7A 2OYHC 1FZAC 4EPUA 1LT9B 4JYOX 2FFDC 2JHLF 2HPCC 1RE3B 2FIBA 2J3FA 2J0HA 2OYIC 2J3FD 1FZCB 2J0GA 4R9TA 3BVHB 4JZCA 3E1IC 1LWUC 1FZGC 1LTJC 1FZBC 1FIBA 2Z4EB 4ZFGA 2J3GA 2HODB 3FIBA 4R9JA 3HUSB 4M7FA 2H43C 1FZCC 2XNXB 1FZFC 1RE4B 1RF1C 1M1JB 1RF0B 2Q9IC 2HLOC 3H32B 2J64A 2J2PA 1N86C 1N73C 4NYTA 1FICA 2HODC 1FZEB 3GHGC 2J0YA 1LT9C 1RE3C 2OYHB 3H32C 1FZAB 2JHIF
chains in the Genus database with same CATH superfamily
3BVHC 2FFDB 2HPCB 2OYIB 2J61A 1FIDA 2Z4EC 2J5ZA 2JHMF 2WNPF 3HUSC 2J3OA 3E1IB 2J61B 1FZGB 1Z3UA 2XNXC 1LTJB 1FZBB 1RE4C 2J1GA 2JHKF 1M1JC 1RF0C 1FZDA 2H43B 1Z3SA 2JHHC 1FZFB 1JC9A 1RF1B 2D39A 2J3UA 1FZEC 2Q9IB 2HLOB 2J60A 1N86B 1N73B 4M7HA 1LWUB 2GY7A 2OYHC 1FZAC 4EPUA 1LT9B 4JYOX 2FFDC 2JHLF 2HPCC 1RE3B 2FIBA 2J3FA 2J0HA 2OYIC 2J3FD 1FZCB 2J0GA 4R9TA 3BVHB 4JZCA 3E1IC 1LWUC 1FZGC 1LTJC 1FZBC 1FIBA 2Z4EB 4ZFGA 2J3GA 2HODB 3FIBA 4R9JA 3HUSB 4M7FA 2H43C 3GHGB 1FZCC 2XNXB 1FZFC 1RE4B 1RF1C 1M1JB 1RF0B 2Q9IC 2HLOC 3H32B 2J64A 2J2PA 1N86C 1N73C 4NYTA 1FICA 2HODC 1FZEB 3GHGC 2J0YA 1LT9C 1RE3C 2OYHB 3H32C 1FZAB 2JHIF
chains in the Genus database with same CATH topology
3BVHC 2FFDB 2HPCB 2OYIB 2J61A 1FIDA 2Z4EC 2J5ZA 2JHMF 2WNPF 3HUSC 2J3OA 3E1IB 2J61B 1FZGB 1Z3UA 2XNXC 1LTJB 1FZBB 1RE4C 2J1GA 2JHKF 1M1JC 1RF0C 1FZDA 2H43B 1Z3SA 2JHHC 1FZFB 1JC9A 1RF1B 2D39A 2J3UA 1FZEC 2Q9IB 2HLOB 2J60A 1N86B 1N73B 4M7HA 1LWUB 2GY7A 2OYHC 1FZAC 4EPUA 1LT9B 4JYOX 2FFDC 2JHLF 2HPCC 1RE3B 2FIBA 2J3FA 2J0HA 2OYIC 2J3FD 1FZCB 2J0GA 4R9TA 3BVHB 4JZCA 3E1IC 1LWUC 1FZGC 1LTJC 1FZBC 1FIBA 2Z4EB 4ZFGA 2J3GA 2HODB 3FIBA 4R9JA 3HUSB 4M7FA 2H43C 1FZCC 2XNXB 1FZFC 1RE4B 1RF1C 1M1JB 1RF0B 2Q9IC 2HLOC 3H32B 2J64A 2J2PA 1N86C 1N73C 4NYTA 1FICA 2HODC 1FZEB 3GHGC 2J0YA 1LT9C 1RE3C 2OYHB 3H32C 1FZAB 2JHIF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BVH C;  2FFD B;  2HPC B;  2OYI B;  2J61 A;  1FID A;  2Z4E C;  2J5Z A;  2JHM F;  2WNP F;  3HUS C;  2J3O A;  3E1I B;  2J61 B;  1FZG B;  1Z3U A;  2XNX C;  1LTJ B;  1FZB B;  1RE4 C;  2J1G A;  2JHK F;  1M1J C;  1RF0 C;  1FZD A;  2H43 B;  1Z3S A;  2JHH C;  1FZF B;  1JC9 A;  1RF1 B;  2D39 A;  2J3U A;  1FZE C;  2Q9I B;  2HLO B;  2J60 A;  1N86 B;  1N73 B;  4M7H A;  1LWU B;  2GY7 A;  2OYH C;  1FZA C;  4EPU A;  1LT9 B;  4JYO X;  2FFD C;  2JHL F;  2HPC C;  1RE3 B;  2FIB A;  2J3F A;  2J0H A;  2OYI C;  2J3F D;  1FZC B;  2J0G A;  4R9T A;  3BVH B;  4JZC A;  3E1I C;  1LWU C;  1FZG C;  1LTJ C;  1FZB C;  1FIB A;  2Z4E B;  4ZFG A;  2J3G A;  2HOD B;  3FIB A;  4R9J A;  3HUS B;  4M7F A;  2H43 C;  1FZC C;  2XNX B;  1FZF C;  1RE4 B;  1RF1 C;  1M1J B;  1RF0 B;  2Q9I C;  2HLO C;  3H32 B;  2J64 A;  2J2P A;  1N86 C;  1N73 C;  4NYT A;  1FIC A;  2HOD C;  1FZE B;  3GHG C;  2J0Y A;  1LT9 C;  1RE3 C;  2OYH B;  3H32 C;  1FZA B;  2JHI F; 
#chains in the Genus database with same CATH topology
 3BVH C;  2FFD B;  2HPC B;  2OYI B;  2J61 A;  1FID A;  2Z4E C;  2J5Z A;  2JHM F;  2WNP F;  3HUS C;  2J3O A;  3E1I B;  2J61 B;  1FZG B;  1Z3U A;  2XNX C;  1LTJ B;  1FZB B;  1RE4 C;  2J1G A;  2JHK F;  1M1J C;  1RF0 C;  1FZD A;  2H43 B;  1Z3S A;  2JHH C;  1FZF B;  1JC9 A;  1RF1 B;  2D39 A;  2J3U A;  1FZE C;  2Q9I B;  2HLO B;  2J60 A;  1N86 B;  1N73 B;  4M7H A;  1LWU B;  2GY7 A;  2OYH C;  1FZA C;  4EPU A;  1LT9 B;  4JYO X;  2FFD C;  2JHL F;  2HPC C;  1RE3 B;  2FIB A;  2J3F A;  2J0H A;  2OYI C;  2J3F D;  1FZC B;  2J0G A;  4R9T A;  3BVH B;  4JZC A;  3E1I C;  1LWU C;  1FZG C;  1LTJ C;  1FZB C;  1FIB A;  2Z4E B;  4ZFG A;  2J3G A;  2HOD B;  3FIB A;  4R9J A;  3HUS B;  4M7F A;  2H43 C;  3GHG B;  1FZC C;  2XNX B;  1FZF C;  1RE4 B;  1RF1 C;  1M1J B;  1RF0 B;  2Q9I C;  2HLO C;  3H32 B;  2J64 A;  2J2P A;  1N86 C;  1N73 C;  4NYT A;  1FIC A;  2HOD C;  1FZE B;  3GHG C;  2J0Y A;  1LT9 C;  1RE3 C;  2OYH B;  3H32 C;  1FZA B;  2JHI F; 
#chains in the Genus database with same CATH homology
 3BVH C;  2FFD B;  2HPC B;  2OYI B;  2J61 A;  1FID A;  2Z4E C;  2J5Z A;  2JHM F;  2WNP F;  3HUS C;  2J3O A;  3E1I B;  2J61 B;  1FZG B;  1Z3U A;  2XNX C;  1LTJ B;  1FZB B;  1RE4 C;  2J1G A;  2JHK F;  1M1J C;  1RF0 C;  1FZD A;  2H43 B;  1Z3S A;  2JHH C;  1FZF B;  1JC9 A;  1RF1 B;  2D39 A;  2J3U A;  1FZE C;  2Q9I B;  2HLO B;  2J60 A;  1N86 B;  1N73 B;  4M7H A;  1LWU B;  2GY7 A;  2OYH C;  1FZA C;  4EPU A;  1LT9 B;  4JYO X;  2FFD C;  2JHL F;  2HPC C;  1RE3 B;  2FIB A;  2J3F A;  2J0H A;  2OYI C;  2J3F D;  1FZC B;  2J0G A;  4R9T A;  3BVH B;  4JZC A;  3E1I C;  1LWU C;  1FZG C;  1LTJ C;  1FZB C;  1FIB A;  2Z4E B;  4ZFG A;  2J3G A;  2HOD B;  3FIB A;  4R9J A;  3HUS B;  4M7F A;  2H43 C;  1FZC C;  2XNX B;  1FZF C;  1RE4 B;  1RF1 C;  1M1J B;  1RF0 B;  2Q9I C;  2HLO C;  3H32 B;  2J64 A;  2J2P A;  1N86 C;  1N73 C;  4NYT A;  1FIC A;  2HOD C;  1FZE B;  3GHG C;  2J0Y A;  1LT9 C;  1RE3 C;  2OYH B;  3H32 C;  1FZA B;  2JHI F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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