1N86C

Crystal structure of human d-dimer from cross-linked fibrin complexed with gpr and ghrpldk peptide ligands.
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
295
structure length
295
Chain Sequence
EASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
publication title The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
pubmed doi rcsb
molecule keywords Fibrin alpha/alpha-E chain
total genus 76
structure length 295
sequence length 295
chains with identical sequence F
ec nomenclature
pdb deposition date 2002-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1n86C01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1n86C02
2XNXC 4M7FA 2JHMF 2J64A 2GY7A 1JC9A 2WNPF 1FZBC 4JYOX 1LT9C 1RF1B 2JHLF 2FIBA 1RF0B 1FZAB 1FZEC 1FZFB 1FZGB 1RF0C 1RE3B 2HODB 2HLOB 4R9JA 1FZGC 3FIBA 4M7HA 2OYIC 2H43C 1N73B 1N86B 2J61B 1N73C 2JHHC 1N86C 2Z4EB 1LTJB 2JHKF 4EPUA 2Z4EC 1FIDA 2J0HA 1RF1C 3BVHB 1FZDA 1FZAC 3H32B 3BVHC 4R9TA 1FICA 1FZFC 2D39A 4NYTA 1RE3C 2HODC 2HLOC 2Q9IB 1Z3UA 3HUSB 2J5ZA 2OYHB 3HUSC 1FZCB 2J61A 1RE4B 2JHIF 1LTJC 2J0GA 3E1IB 2J1GA 2J3FA 3E1IC 2J60A 1LWUB 2XNXB 3GHGC 2J3GA 1M1JB 3H32C 2J0YA 2J3UA 1M1JC 2J3FD 2Q9IC 1FZBB 1FIBA 1LT9B 2J3OA 2OYHC 1FZEB 2HPCB 1FZCC 2FFDB 1RE4C 2HPCC 4JZCA 2FFDC 1Z3SA 2OYIB 2J2PA 2H43B 4ZFGA 1LWUC
chains in the Genus database with same CATH superfamily
2XNXC 4M7FA 2JHMF 2J64A 2GY7A 1JC9A 2WNPF 1FZBC 4JYOX 1LT9C 1RF1B 2JHLF 2FIBA 1RF0B 1FZAB 1FZEC 1FZFB 1FZGB 1RF0C 1RE3B 2HODB 2HLOB 4R9JA 1FZGC 3FIBA 4M7HA 2OYIC 2H43C 1N73B 1N86B 2J61B 1N73C 2JHHC 1N86C 2Z4EB 1LTJB 2JHKF 4EPUA 2Z4EC 1FIDA 2J0HA 1RF1C 3BVHB 1FZDA 1FZAC 3H32B 3BVHC 4R9TA 1FICA 1FZFC 2D39A 4NYTA 1RE3C 2HODC 2HLOC 2Q9IB 1Z3UA 3HUSB 2J5ZA 2OYHB 3HUSC 1FZCB 2J61A 1RE4B 2JHIF 1LTJC 2J0GA 3E1IB 2J1GA 2J3FA 3E1IC 2J60A 3GHGB 1LWUB 2XNXB 3GHGC 2J3GA 1M1JB 3H32C 2J0YA 2J3UA 1M1JC 2J3FD 2Q9IC 1FZBB 1FIBA 1LT9B 2J3OA 2OYHC 1FZEB 2HPCB 1FZCC 2FFDB 1RE4C 2HPCC 4JZCA 2FFDC 1Z3SA 2OYIB 2J2PA 2H43B 4ZFGA 1LWUC
chains in the Genus database with same CATH topology
2XNXC 4M7FA 2JHMF 2J64A 2GY7A 1JC9A 2WNPF 1FZBC 4JYOX 1LT9C 1RF1B 2JHLF 2FIBA 1RF0B 1FZAB 1FZEC 1FZFB 1FZGB 1RF0C 1RE3B 2HODB 2HLOB 4R9JA 1FZGC 3FIBA 4M7HA 2OYIC 2H43C 1N73B 1N86B 2J61B 1N73C 2JHHC 1N86C 2Z4EB 1LTJB 2JHKF 4EPUA 2Z4EC 1FIDA 2J0HA 1RF1C 3BVHB 1FZDA 1FZAC 3H32B 3BVHC 4R9TA 1FICA 1FZFC 2D39A 4NYTA 1RE3C 2HODC 2HLOC 2Q9IB 1Z3UA 3HUSB 2J5ZA 2OYHB 3HUSC 1FZCB 2J61A 1RE4B 2JHIF 1LTJC 2J0GA 3E1IB 2J1GA 2J3FA 3E1IC 2J60A 1LWUB 2XNXB 3GHGC 2J3GA 1M1JB 3H32C 2J0YA 2J3UA 1M1JC 2J3FD 2Q9IC 1FZBB 1FIBA 1LT9B 2J3OA 2OYHC 1FZEB 2HPCB 1FZCC 2FFDB 1RE4C 2HPCC 4JZCA 2FFDC 1Z3SA 2OYIB 2J2PA 2H43B 4ZFGA 1LWUC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XNX C;  4M7F A;  2JHM F;  2J64 A;  2GY7 A;  1JC9 A;  2WNP F;  1FZB C;  4JYO X;  1LT9 C;  1RF1 B;  2JHL F;  2FIB A;  1RF0 B;  1FZA B;  1FZE C;  1FZF B;  1FZG B;  1RF0 C;  1RE3 B;  2HOD B;  2HLO B;  4R9J A;  1FZG C;  3FIB A;  4M7H A;  2OYI C;  2H43 C;  1N73 B;  1N86 B;  2J61 B;  1N73 C;  2JHH C;  1N86 C;  2Z4E B;  1LTJ B;  2JHK F;  4EPU A;  2Z4E C;  1FID A;  2J0H A;  1RF1 C;  3BVH B;  1FZD A;  1FZA C;  3H32 B;  3BVH C;  4R9T A;  1FIC A;  1FZF C;  2D39 A;  4NYT A;  1RE3 C;  2HOD C;  2HLO C;  2Q9I B;  1Z3U A;  3HUS B;  2J5Z A;  2OYH B;  3HUS C;  1FZC B;  2J61 A;  1RE4 B;  2JHI F;  1LTJ C;  2J0G A;  3E1I B;  2J1G A;  2J3F A;  3E1I C;  2J60 A;  1LWU B;  2XNX B;  3GHG C;  2J3G A;  1M1J B;  3H32 C;  2J0Y A;  2J3U A;  1M1J C;  2J3F D;  2Q9I C;  1FZB B;  1FIB A;  1LT9 B;  2J3O A;  2OYH C;  1FZE B;  2HPC B;  1FZC C;  2FFD B;  1RE4 C;  2HPC C;  4JZC A;  2FFD C;  1Z3S A;  2OYI B;  2J2P A;  2H43 B;  4ZFG A;  1LWU C; 
#chains in the Genus database with same CATH topology
 2XNX C;  4M7F A;  2JHM F;  2J64 A;  2GY7 A;  1JC9 A;  2WNP F;  1FZB C;  4JYO X;  1LT9 C;  1RF1 B;  2JHL F;  2FIB A;  1RF0 B;  1FZA B;  1FZE C;  1FZF B;  1FZG B;  1RF0 C;  1RE3 B;  2HOD B;  2HLO B;  4R9J A;  1FZG C;  3FIB A;  4M7H A;  2OYI C;  2H43 C;  1N73 B;  1N86 B;  2J61 B;  1N73 C;  2JHH C;  1N86 C;  2Z4E B;  1LTJ B;  2JHK F;  4EPU A;  2Z4E C;  1FID A;  2J0H A;  1RF1 C;  3BVH B;  1FZD A;  1FZA C;  3H32 B;  3BVH C;  4R9T A;  1FIC A;  1FZF C;  2D39 A;  4NYT A;  1RE3 C;  2HOD C;  2HLO C;  2Q9I B;  1Z3U A;  3HUS B;  2J5Z A;  2OYH B;  3HUS C;  1FZC B;  2J61 A;  1RE4 B;  2JHI F;  1LTJ C;  2J0G A;  3E1I B;  2J1G A;  2J3F A;  3E1I C;  2J60 A;  3GHG B;  1LWU B;  2XNX B;  3GHG C;  2J3G A;  1M1J B;  3H32 C;  2J0Y A;  2J3U A;  1M1J C;  2J3F D;  2Q9I C;  1FZB B;  1FIB A;  1LT9 B;  2J3O A;  2OYH C;  1FZE B;  2HPC B;  1FZC C;  2FFD B;  1RE4 C;  2HPC C;  4JZC A;  2FFD C;  1Z3S A;  2OYI B;  2J2P A;  2H43 B;  4ZFG A;  1LWU C; 
#chains in the Genus database with same CATH homology
 2XNX C;  4M7F A;  2JHM F;  2J64 A;  2GY7 A;  1JC9 A;  2WNP F;  1FZB C;  4JYO X;  1LT9 C;  1RF1 B;  2JHL F;  2FIB A;  1RF0 B;  1FZA B;  1FZE C;  1FZF B;  1FZG B;  1RF0 C;  1RE3 B;  2HOD B;  2HLO B;  4R9J A;  1FZG C;  3FIB A;  4M7H A;  2OYI C;  2H43 C;  1N73 B;  1N86 B;  2J61 B;  1N73 C;  2JHH C;  1N86 C;  2Z4E B;  1LTJ B;  2JHK F;  4EPU A;  2Z4E C;  1FID A;  2J0H A;  1RF1 C;  3BVH B;  1FZD A;  1FZA C;  3H32 B;  3BVH C;  4R9T A;  1FIC A;  1FZF C;  2D39 A;  4NYT A;  1RE3 C;  2HOD C;  2HLO C;  2Q9I B;  1Z3U A;  3HUS B;  2J5Z A;  2OYH B;  3HUS C;  1FZC B;  2J61 A;  1RE4 B;  2JHI F;  1LTJ C;  2J0G A;  3E1I B;  2J1G A;  2J3F A;  3E1I C;  2J60 A;  1LWU B;  2XNX B;  3GHG C;  2J3G A;  1M1J B;  3H32 C;  2J0Y A;  2J3U A;  1M1J C;  2J3F D;  2Q9I C;  1FZB B;  1FIB A;  1LT9 B;  2J3O A;  2OYH C;  1FZE B;  2HPC B;  1FZC C;  2FFD B;  1RE4 C;  2HPC C;  4JZC A;  2FFD C;  1Z3S A;  2OYI B;  2J2P A;  2H43 B;  4ZFG A;  1LWU C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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