1N86 | Genus

Total Genus 76

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	76
sequence length	295
structure length	295
Chain Sequence	EASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Blood clotting
publication title	The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface. pubmed doi rcsb
molecule keywords	Fibrin alpha/alpha-E chain
total genus	76
structure length	295
sequence length	295
chains with identical sequence	F
ec nomenclature
pdb deposition date	2002-11-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF00147	Fibrinogen_C	Fibrinogen beta and gamma chains, C-terminal globular domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.215.10	Alpha Beta	Alpha-Beta Complex	Gamma Fibrinogen; Chain A, domain 1	Gamma Fibrinogen, chain A, domain 1	1n86C01
4.10.530.10	Few Secondary Structures	Irregular	Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2	Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2	1n86C02

1RE3C 1FZAC 3E1IB 2JHMF 2J1GA 2J3GA 2J2PA 1FZAB 1RE4B 2H43C 3BVHB 2WNPF 2OYHC 2J64A 4EPUA 1FICA 2J0YA 2J60A 4M7FA 3HUSC 3GHGC 3H32B 2J61B 1LWUB 1RF0C 1FZEB 2J0HA 2FFDB 2Z4EB 4ZFGA 1FZFC 4NYTA 1FZGB 1FIBA 1FZFB 2JHKF 3E1IC 1LT9C 2HPCB 2J0GA 1RE4C 3BVHC 1FZBB 1LT9B 2Q9IC 2J3FA 2J3FD 2J3OA 1M1JB 4JZCA 1N73B 2Q9IB 3H32C 1LWUC 2FFDC 1FZEC 2Z4EC 1FZGC 1LTJB 2HPCC 1N86B 2JHIF 2D39A 1FZBC 1N73C 1M1JC 2JHLF 1JC9A 4R9TA 2GY7A 4JYOX 1FZCB 1FZDA 2J3UA 1LTJC 3FIBA 1Z3UA 2HODB 2HLOB 2XNXC 1N86C 2OYIC 4R9JA 2XNXB 2OYIB 4M7HA 1RE3B 2J61A 1FIDA 2H43B 2FIBA 1RF1C 2OYHB 1FZCC 2J5ZA 1RF1B 1Z3SA 2HLOC 2HODC 2JHHC 3HUSB 1RF0B
chains in the Genus database with same CATH superfamily

1RE3C 1FZAC 3E1IB 2JHMF 2J1GA 2J3GA 2J2PA 1FZAB 1RE4B 2H43C 3BVHB 2WNPF 2OYHC 2J64A 4EPUA 1FICA 2J0YA 2J60A 4M7FA 3HUSC 3GHGC 3H32B 2J61B 1LWUB 1RF0C 1FZEB 2J0HA 2FFDB 2Z4EB 4ZFGA 1FZFC 3GHGB 4NYTA 1FZGB 1FIBA 1FZFB 2JHKF 3E1IC 1LT9C 2HPCB 2J0GA 1RE4C 3BVHC 1FZBB 1LT9B 2Q9IC 2J3FA 2J3FD 2J3OA 1M1JB 4JZCA 1N73B 2Q9IB 3H32C 1LWUC 2FFDC 1FZEC 2Z4EC 1FZGC 1LTJB 2HPCC 1N86B 2JHIF 2D39A 1FZBC 1N73C 1M1JC 2JHLF 1JC9A 4R9TA 2GY7A 4JYOX 1FZCB 1FZDA 2J3UA 1LTJC 3FIBA 1Z3UA 2HODB 2HLOB 2XNXC 1N86C 2OYIC 4R9JA 2XNXB 2OYIB 4M7HA 1RE3B 2J61A 1FIDA 2H43B 2FIBA 1RF1C 2OYHB 1FZCC 2J5ZA 1RF1B 1Z3SA 2HLOC 2HODC 2JHHC 3HUSB 1RF0B
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1RE3 C;  1FZA C;  3E1I B;  2JHM F;  2J1G A;  2J3G A;  2J2P A;  1FZA B;  1RE4 B;  2H43 C;  3BVH B;  2WNP F;  2OYH C;  2J64 A;  4EPU A;  1FIC A;  2J0Y A;  2J60 A;  4M7F A;  3HUS C;  3GHG C;  3H32 B;  2J61 B;  1LWU B;  1RF0 C;  1FZE B;  2J0H A;  2FFD B;  2Z4E B;  4ZFG A;  1FZF C;  4NYT A;  1FZG B;  1FIB A;  1FZF B;  2JHK F;  3E1I C;  1LT9 C;  2HPC B;  2J0G A;  1RE4 C;  3BVH C;  1FZB B;  1LT9 B;  2Q9I C;  2J3F A;  2J3F D;  2J3O A;  1M1J B;  4JZC A;  1N73 B;  2Q9I B;  3H32 C;  1LWU C;  2FFD C;  1FZE C;  2Z4E C;  1FZG C;  1LTJ B;  2HPC C;  1N86 B;  2JHI F;  2D39 A;  1FZB C;  1N73 C;  1M1J C;  2JHL F;  1JC9 A;  4R9T A;  2GY7 A;  4JYO X;  1FZC B;  1FZD A;  2J3U A;  1LTJ C;  3FIB A;  1Z3U A;  2HOD B;  2HLO B;  2XNX C;  1N86 C;  2OYI C;  4R9J A;  2XNX B;  2OYI B;  4M7H A;  1RE3 B;  2J61 A;  1FID A;  2H43 B;  2FIB A;  1RF1 C;  2OYH B;  1FZC C;  2J5Z A;  1RF1 B;  1Z3S A;  2HLO C;  2HOD C;  2JHH C;  3HUS B;  1RF0 B; 
#chains in the Genus database with same CATH topology
 1RE3 C;  1FZA C;  3E1I B;  2JHM F;  2J1G A;  2J3G A;  2J2P A;  1FZA B;  1RE4 B;  2H43 C;  3BVH B;  2WNP F;  2OYH C;  2J64 A;  4EPU A;  1FIC A;  2J0Y A;  2J60 A;  4M7F A;  3HUS C;  3GHG C;  3H32 B;  2J61 B;  1LWU B;  1RF0 C;  1FZE B;  2J0H A;  2FFD B;  2Z4E B;  4ZFG A;  1FZF C;  3GHG B;  4NYT A;  1FZG B;  1FIB A;  1FZF B;  2JHK F;  3E1I C;  1LT9 C;  2HPC B;  2J0G A;  1RE4 C;  3BVH C;  1FZB B;  1LT9 B;  2Q9I C;  2J3F A;  2J3F D;  2J3O A;  1M1J B;  4JZC A;  1N73 B;  2Q9I B;  3H32 C;  1LWU C;  2FFD C;  1FZE C;  2Z4E C;  1FZG C;  1LTJ B;  2HPC C;  1N86 B;  2JHI F;  2D39 A;  1FZB C;  1N73 C;  1M1J C;  2JHL F;  1JC9 A;  4R9T A;  2GY7 A;  4JYO X;  1FZC B;  1FZD A;  2J3U A;  1LTJ C;  3FIB A;  1Z3U A;  2HOD B;  2HLO B;  2XNX C;  1N86 C;  2OYI C;  4R9J A;  2XNX B;  2OYI B;  4M7H A;  1RE3 B;  2J61 A;  1FID A;  2H43 B;  2FIB A;  1RF1 C;  2OYH B;  1FZC C;  2J5Z A;  1RF1 B;  1Z3S A;  2HLO C;  2HOD C;  2JHH C;  3HUS B;  1RF0 B; 
#chains in the Genus database with same CATH homology
 1RE3 C;  1FZA C;  3E1I B;  2JHM F;  2J1G A;  2J3G A;  2J2P A;  1FZA B;  1RE4 B;  2H43 C;  3BVH B;  2WNP F;  2OYH C;  2J64 A;  4EPU A;  1FIC A;  2J0Y A;  2J60 A;  4M7F A;  3HUS C;  3GHG C;  3H32 B;  2J61 B;  1LWU B;  1RF0 C;  1FZE B;  2J0H A;  2FFD B;  2Z4E B;  4ZFG A;  1FZF C;  4NYT A;  1FZG B;  1FIB A;  1FZF B;  2JHK F;  3E1I C;  1LT9 C;  2HPC B;  2J0G A;  1RE4 C;  3BVH C;  1FZB B;  1LT9 B;  2Q9I C;  2J3F A;  2J3F D;  2J3O A;  1M1J B;  4JZC A;  1N73 B;  2Q9I B;  3H32 C;  1LWU C;  2FFD C;  1FZE C;  2Z4E C;  1FZG C;  1LTJ B;  2HPC C;  1N86 B;  2JHI F;  2D39 A;  1FZB C;  1N73 C;  1M1J C;  2JHL F;  1JC9 A;  4R9T A;  2GY7 A;  4JYO X;  1FZC B;  1FZD A;  2J3U A;  1LTJ C;  3FIB A;  1Z3U A;  2HOD B;  2HLO B;  2XNX C;  1N86 C;  2OYI C;  4R9J A;  2XNX B;  2OYI B;  4M7H A;  1RE3 B;  2J61 A;  1FID A;  2H43 B;  2FIB A;  1RF1 C;  2OYH B;  1FZC C;  2J5Z A;  1RF1 B;  1Z3S A;  2HLO C;  2HOD C;  2JHH C;  3HUS B;  1RF0 B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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1N86C

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations