1RE3B

Crystal structure of fragment d of bbetad398a fibrinogen with the peptide ligand gly-his-arg-pro-amide
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
294
structure length
294
Chain Sequence
LRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEAGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
source organism Homo sapiens
publication title BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
pubmed doi rcsb
molecule keywords Fibrinogen alpha/alpha-E chain
total genus 87
structure length 294
sequence length 294
chains with identical sequence E
ec nomenclature
pdb deposition date 2003-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1re3B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1re3B02
4M7HA 2J0HA 1LTJC 1FZDA 1FIBA 2JHMF 4ZFGA 2HPCB 2OYIB 2J61B 1FZCC 2HPCC 2J3FA 2OYIC 1Z3UA 4R9TA 1N73B 2HLOB 1FIDA 1FICA 1FZEB 1N73C 2J3UA 3GHGC 2FIBA 1LWUB 4EPUA 2Z4EB 2J3OA 1LWUC 2XNXB 2Z4EC 2H43B 2J1GA 2JHHC 1RE3B 1RF1B 4R9JA 2J61A 1RF1C 2J2PA 2GY7A 1N86B 1RE4B 2HLOC 4NYTA 1FZFB 1FZEC 1JC9A 1LT9B 1FZAB 2Q9IB 2JHKF 3E1IB 2OYHB 2J5ZA 2OYHC 1FZGB 2FFDB 1Z3SA 2J0YA 2D39A 2XNXC 2J3GA 2J0GA 2J3FD 2JHLF 2JHIF 2WNPF 2H43C 4JZCA 4M7FA 1FZGC 1M1JB 1RE3C 2J60A 1FZBB 1LTJB 1M1JC 1FZBC 3H32B 3BVHB 1N86C 1RE4C 3H32C 3BVHC 3FIBA 1RF0B 1FZFC 1FZCB 3HUSB 2Q9IC 1LT9C 1FZAC 1RF0C 3E1IC 2J64A 3HUSC 2HODB 4JYOX 2FFDC 2HODC
chains in the Genus database with same CATH superfamily
4M7HA 2J0HA 1LTJC 1FZDA 1FIBA 2JHMF 4ZFGA 2HPCB 2OYIB 2J61B 1FZCC 2HPCC 2J3FA 2OYIC 1Z3UA 4R9TA 1N73B 2HLOB 1FIDA 1FICA 1FZEB 1N73C 2J3UA 3GHGC 2FIBA 1LWUB 4EPUA 2Z4EB 2J3OA 1LWUC 2XNXB 2Z4EC 2H43B 2J1GA 2JHHC 1RE3B 1RF1B 4R9JA 2J61A 1RF1C 2J2PA 2GY7A 1N86B 1RE4B 2HLOC 4NYTA 1FZFB 1FZEC 1JC9A 1LT9B 1FZAB 2Q9IB 2JHKF 3E1IB 2OYHB 2J5ZA 2OYHC 1FZGB 2FFDB 1Z3SA 2J0YA 2D39A 2XNXC 2J3GA 2J0GA 2J3FD 2JHLF 2JHIF 2WNPF 2H43C 4JZCA 4M7FA 1FZGC 1M1JB 1RE3C 2J60A 1FZBB 1LTJB 1M1JC 1FZBC 3H32B 3BVHB 1N86C 1RE4C 3H32C 3BVHC 3FIBA 1RF0B 1FZFC 1FZCB 3HUSB 2Q9IC 1LT9C 1FZAC 1RF0C 3E1IC 2J64A 3HUSC 2HODB 4JYOX 2FFDC 2HODC 3GHGB
chains in the Genus database with same CATH topology
4M7HA 2J0HA 1LTJC 1FZDA 1FIBA 2JHMF 4ZFGA 2HPCB 2OYIB 2J61B 1FZCC 2HPCC 2J3FA 2OYIC 1Z3UA 4R9TA 1N73B 2HLOB 1FIDA 1FICA 1FZEB 1N73C 2J3UA 3GHGC 2FIBA 1LWUB 4EPUA 2Z4EB 2J3OA 1LWUC 2XNXB 2Z4EC 2H43B 2J1GA 2JHHC 1RE3B 1RF1B 4R9JA 2J61A 1RF1C 2J2PA 2GY7A 1N86B 1RE4B 2HLOC 4NYTA 1FZFB 1FZEC 1JC9A 1LT9B 1FZAB 2Q9IB 2JHKF 3E1IB 2OYHB 2J5ZA 2OYHC 1FZGB 2FFDB 1Z3SA 2J0YA 2D39A 2XNXC 2J3GA 2J0GA 2J3FD 2JHLF 2JHIF 2WNPF 2H43C 4JZCA 4M7FA 1FZGC 1M1JB 1RE3C 2J60A 1FZBB 1LTJB 1M1JC 1FZBC 3H32B 3BVHB 1N86C 1RE4C 3H32C 3BVHC 3FIBA 1RF0B 1FZFC 1FZCB 3HUSB 2Q9IC 1LT9C 1FZAC 1RF0C 3E1IC 2J64A 3HUSC 2HODB 4JYOX 2FFDC 2HODC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4M7H A;  2J0H A;  1LTJ C;  1FZD A;  1FIB A;  2JHM F;  4ZFG A;  2HPC B;  2OYI B;  2J61 B;  1FZC C;  2HPC C;  2J3F A;  2OYI C;  1Z3U A;  4R9T A;  1N73 B;  2HLO B;  1FID A;  1FIC A;  1FZE B;  1N73 C;  2J3U A;  3GHG C;  2FIB A;  1LWU B;  4EPU A;  2Z4E B;  2J3O A;  1LWU C;  2XNX B;  2Z4E C;  2H43 B;  2J1G A;  2JHH C;  1RE3 B;  1RF1 B;  4R9J A;  2J61 A;  1RF1 C;  2J2P A;  2GY7 A;  1N86 B;  1RE4 B;  2HLO C;  4NYT A;  1FZF B;  1FZE C;  1JC9 A;  1LT9 B;  1FZA B;  2Q9I B;  2JHK F;  3E1I B;  2OYH B;  2J5Z A;  2OYH C;  1FZG B;  2FFD B;  1Z3S A;  2J0Y A;  2D39 A;  2XNX C;  2J3G A;  2J0G A;  2J3F D;  2JHL F;  2JHI F;  2WNP F;  2H43 C;  4JZC A;  4M7F A;  1FZG C;  1M1J B;  1RE3 C;  2J60 A;  1FZB B;  1LTJ B;  1M1J C;  1FZB C;  3H32 B;  3BVH B;  1N86 C;  1RE4 C;  3H32 C;  3BVH C;  3FIB A;  1RF0 B;  1FZF C;  1FZC B;  3HUS B;  2Q9I C;  1LT9 C;  1FZA C;  1RF0 C;  3E1I C;  2J64 A;  3HUS C;  2HOD B;  4JYO X;  2FFD C;  2HOD C; 
#chains in the Genus database with same CATH topology
 4M7H A;  2J0H A;  1LTJ C;  1FZD A;  1FIB A;  2JHM F;  4ZFG A;  2HPC B;  2OYI B;  2J61 B;  1FZC C;  2HPC C;  2J3F A;  2OYI C;  1Z3U A;  4R9T A;  1N73 B;  2HLO B;  1FID A;  1FIC A;  1FZE B;  1N73 C;  2J3U A;  3GHG C;  2FIB A;  1LWU B;  4EPU A;  2Z4E B;  2J3O A;  1LWU C;  2XNX B;  2Z4E C;  2H43 B;  2J1G A;  2JHH C;  1RE3 B;  1RF1 B;  4R9J A;  2J61 A;  1RF1 C;  2J2P A;  2GY7 A;  1N86 B;  1RE4 B;  2HLO C;  4NYT A;  1FZF B;  1FZE C;  1JC9 A;  1LT9 B;  1FZA B;  2Q9I B;  2JHK F;  3E1I B;  2OYH B;  2J5Z A;  2OYH C;  1FZG B;  2FFD B;  1Z3S A;  2J0Y A;  2D39 A;  2XNX C;  2J3G A;  2J0G A;  2J3F D;  2JHL F;  2JHI F;  2WNP F;  2H43 C;  4JZC A;  4M7F A;  1FZG C;  1M1J B;  1RE3 C;  2J60 A;  1FZB B;  1LTJ B;  1M1J C;  1FZB C;  3H32 B;  3BVH B;  1N86 C;  1RE4 C;  3H32 C;  3BVH C;  3FIB A;  1RF0 B;  1FZF C;  1FZC B;  3HUS B;  2Q9I C;  1LT9 C;  1FZA C;  1RF0 C;  3E1I C;  2J64 A;  3HUS C;  2HOD B;  4JYO X;  2FFD C;  2HOD C;  3GHG B; 
#chains in the Genus database with same CATH homology
 4M7H A;  2J0H A;  1LTJ C;  1FZD A;  1FIB A;  2JHM F;  4ZFG A;  2HPC B;  2OYI B;  2J61 B;  1FZC C;  2HPC C;  2J3F A;  2OYI C;  1Z3U A;  4R9T A;  1N73 B;  2HLO B;  1FID A;  1FIC A;  1FZE B;  1N73 C;  2J3U A;  3GHG C;  2FIB A;  1LWU B;  4EPU A;  2Z4E B;  2J3O A;  1LWU C;  2XNX B;  2Z4E C;  2H43 B;  2J1G A;  2JHH C;  1RE3 B;  1RF1 B;  4R9J A;  2J61 A;  1RF1 C;  2J2P A;  2GY7 A;  1N86 B;  1RE4 B;  2HLO C;  4NYT A;  1FZF B;  1FZE C;  1JC9 A;  1LT9 B;  1FZA B;  2Q9I B;  2JHK F;  3E1I B;  2OYH B;  2J5Z A;  2OYH C;  1FZG B;  2FFD B;  1Z3S A;  2J0Y A;  2D39 A;  2XNX C;  2J3G A;  2J0G A;  2J3F D;  2JHL F;  2JHI F;  2WNP F;  2H43 C;  4JZC A;  4M7F A;  1FZG C;  1M1J B;  1RE3 C;  2J60 A;  1FZB B;  1LTJ B;  1M1J C;  1FZB C;  3H32 B;  3BVH B;  1N86 C;  1RE4 C;  3H32 C;  3BVH C;  3FIB A;  1RF0 B;  1FZF C;  1FZC B;  3HUS B;  2Q9I C;  1LT9 C;  1FZA C;  1RF0 C;  3E1I C;  2J64 A;  3HUS C;  2HOD B;  4JYO X;  2FFD C;  2HOD C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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