1FZEC

Crystal structure of fragment double-d from human fibrin
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
303
structure length
303
Chain Sequence
EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 85
structure length 303
sequence length 303
chains with identical sequence F
ec nomenclature
pdb deposition date 1998-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzeC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzeC02
3HUSB 2J3FA 2OYHC 1FIBA 1FZCB 4EPUA 2J0GA 4JYOX 4JZCA 1LT9C 1FIDA 3E1IC 1FZBC 1M1JC 1FZBB 2JHKF 2JHMF 1N73C 4R9TA 1RF0C 2J61B 2WNPF 1LTJB 2J5ZA 2JHIF 2FIBA 3GHGC 2Z4EC 2HLOB 2J3UA 2Q9IB 1RE3C 2HPCC 1FZDA 1Z3SA 1JC9A 2OYHB 1FZGC 2OYIC 4R9JA 3BVHC 1FZGB 2J61A 2J0HA 1LT9B 3E1IB 2FFDC 3FIBA 1FICA 2D39A 1M1JB 1N73B 1RF0B 1LWUC 2GY7A 2H43C 1N86C 2JHLF 2Z4EB 2H43B 1FZEC 1RE3B 2HPCB 3H32C 2HODC 4M7HA 3H32B 2OYIB 1RF1C 3BVHB 1FZAC 2XNXC 1FZAB 2FFDB 1Z3UA 2JHHC 1FZCC 2J64A 1LWUB 2J60A 2J3GA 1N86B 2J1GA 2J0YA 1FZEB 4ZFGA 1FZFC 2J2PA 2HODB 1FZFB 4NYTA 1LTJC 1RE4C 2J3FD 1RF1B 2J3OA 1RE4B 4M7FA 3HUSC 2HLOC 2XNXB 2Q9IC
chains in the Genus database with same CATH superfamily
3HUSB 2J3FA 2OYHC 1FIBA 1FZCB 4EPUA 2J0GA 4JYOX 4JZCA 1LT9C 1FIDA 3E1IC 1FZBC 1M1JC 1FZBB 2JHKF 2JHMF 1N73C 4R9TA 1RF0C 2J61B 2WNPF 1LTJB 2J5ZA 2JHIF 2FIBA 3GHGC 2Z4EC 2HLOB 3GHGB 2J3UA 2Q9IB 1RE3C 2HPCC 1FZDA 1Z3SA 1JC9A 2OYHB 1FZGC 2OYIC 4R9JA 3BVHC 1FZGB 2J61A 2J0HA 1LT9B 3E1IB 2FFDC 3FIBA 1FICA 2D39A 1M1JB 1N73B 1RF0B 1LWUC 2GY7A 2H43C 1N86C 2JHLF 2Z4EB 2H43B 1FZEC 1RE3B 2HPCB 3H32C 2HODC 4M7HA 3H32B 2OYIB 1RF1C 3BVHB 1FZAC 2XNXC 1FZAB 2FFDB 1Z3UA 2JHHC 1FZCC 2J64A 1LWUB 2J60A 2J3GA 1N86B 2J1GA 2J0YA 1FZEB 4ZFGA 1FZFC 2J2PA 2HODB 1FZFB 4NYTA 1LTJC 1RE4C 2J3FD 1RF1B 2J3OA 1RE4B 4M7FA 3HUSC 2HLOC 2XNXB 2Q9IC
chains in the Genus database with same CATH topology
3HUSB 2J3FA 2OYHC 1FIBA 1FZCB 4EPUA 2J0GA 4JYOX 4JZCA 1LT9C 1FIDA 3E1IC 1FZBC 1M1JC 1FZBB 2JHKF 2JHMF 1N73C 4R9TA 1RF0C 2J61B 2WNPF 1LTJB 2J5ZA 2JHIF 2FIBA 3GHGC 2Z4EC 2HLOB 2J3UA 2Q9IB 1RE3C 2HPCC 1FZDA 1Z3SA 1JC9A 2OYHB 1FZGC 2OYIC 4R9JA 3BVHC 1FZGB 2J61A 2J0HA 1LT9B 3E1IB 2FFDC 3FIBA 1FICA 2D39A 1M1JB 1N73B 1RF0B 1LWUC 2GY7A 2H43C 1N86C 2JHLF 2Z4EB 2H43B 1FZEC 1RE3B 2HPCB 3H32C 2HODC 4M7HA 3H32B 2OYIB 1RF1C 3BVHB 1FZAC 2XNXC 1FZAB 2FFDB 1Z3UA 2JHHC 1FZCC 2J64A 1LWUB 2J60A 2J3GA 1N86B 2J1GA 2J0YA 1FZEB 4ZFGA 1FZFC 2J2PA 2HODB 1FZFB 4NYTA 1LTJC 1RE4C 2J3FD 1RF1B 2J3OA 1RE4B 4M7FA 3HUSC 2HLOC 2XNXB 2Q9IC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HUS B;  2J3F A;  2OYH C;  1FIB A;  1FZC B;  4EPU A;  2J0G A;  4JYO X;  4JZC A;  1LT9 C;  1FID A;  3E1I C;  1FZB C;  1M1J C;  1FZB B;  2JHK F;  2JHM F;  1N73 C;  4R9T A;  1RF0 C;  2J61 B;  2WNP F;  1LTJ B;  2J5Z A;  2JHI F;  2FIB A;  3GHG C;  2Z4E C;  2HLO B;  2J3U A;  2Q9I B;  1RE3 C;  2HPC C;  1FZD A;  1Z3S A;  1JC9 A;  2OYH B;  1FZG C;  2OYI C;  4R9J A;  3BVH C;  1FZG B;  2J61 A;  2J0H A;  1LT9 B;  3E1I B;  2FFD C;  3FIB A;  1FIC A;  2D39 A;  1M1J B;  1N73 B;  1RF0 B;  1LWU C;  2GY7 A;  2H43 C;  1N86 C;  2JHL F;  2Z4E B;  2H43 B;  1FZE C;  1RE3 B;  2HPC B;  3H32 C;  2HOD C;  4M7H A;  3H32 B;  2OYI B;  1RF1 C;  3BVH B;  1FZA C;  2XNX C;  1FZA B;  2FFD B;  1Z3U A;  2JHH C;  1FZC C;  2J64 A;  1LWU B;  2J60 A;  2J3G A;  1N86 B;  2J1G A;  2J0Y A;  1FZE B;  4ZFG A;  1FZF C;  2J2P A;  2HOD B;  1FZF B;  4NYT A;  1LTJ C;  1RE4 C;  2J3F D;  1RF1 B;  2J3O A;  1RE4 B;  4M7F A;  3HUS C;  2HLO C;  2XNX B;  2Q9I C; 
#chains in the Genus database with same CATH topology
 3HUS B;  2J3F A;  2OYH C;  1FIB A;  1FZC B;  4EPU A;  2J0G A;  4JYO X;  4JZC A;  1LT9 C;  1FID A;  3E1I C;  1FZB C;  1M1J C;  1FZB B;  2JHK F;  2JHM F;  1N73 C;  4R9T A;  1RF0 C;  2J61 B;  2WNP F;  1LTJ B;  2J5Z A;  2JHI F;  2FIB A;  3GHG C;  2Z4E C;  2HLO B;  3GHG B;  2J3U A;  2Q9I B;  1RE3 C;  2HPC C;  1FZD A;  1Z3S A;  1JC9 A;  2OYH B;  1FZG C;  2OYI C;  4R9J A;  3BVH C;  1FZG B;  2J61 A;  2J0H A;  1LT9 B;  3E1I B;  2FFD C;  3FIB A;  1FIC A;  2D39 A;  1M1J B;  1N73 B;  1RF0 B;  1LWU C;  2GY7 A;  2H43 C;  1N86 C;  2JHL F;  2Z4E B;  2H43 B;  1FZE C;  1RE3 B;  2HPC B;  3H32 C;  2HOD C;  4M7H A;  3H32 B;  2OYI B;  1RF1 C;  3BVH B;  1FZA C;  2XNX C;  1FZA B;  2FFD B;  1Z3U A;  2JHH C;  1FZC C;  2J64 A;  1LWU B;  2J60 A;  2J3G A;  1N86 B;  2J1G A;  2J0Y A;  1FZE B;  4ZFG A;  1FZF C;  2J2P A;  2HOD B;  1FZF B;  4NYT A;  1LTJ C;  1RE4 C;  2J3F D;  1RF1 B;  2J3O A;  1RE4 B;  4M7F A;  3HUS C;  2HLO C;  2XNX B;  2Q9I C; 
#chains in the Genus database with same CATH homology
 3HUS B;  2J3F A;  2OYH C;  1FIB A;  1FZC B;  4EPU A;  2J0G A;  4JYO X;  4JZC A;  1LT9 C;  1FID A;  3E1I C;  1FZB C;  1M1J C;  1FZB B;  2JHK F;  2JHM F;  1N73 C;  4R9T A;  1RF0 C;  2J61 B;  2WNP F;  1LTJ B;  2J5Z A;  2JHI F;  2FIB A;  3GHG C;  2Z4E C;  2HLO B;  2J3U A;  2Q9I B;  1RE3 C;  2HPC C;  1FZD A;  1Z3S A;  1JC9 A;  2OYH B;  1FZG C;  2OYI C;  4R9J A;  3BVH C;  1FZG B;  2J61 A;  2J0H A;  1LT9 B;  3E1I B;  2FFD C;  3FIB A;  1FIC A;  2D39 A;  1M1J B;  1N73 B;  1RF0 B;  1LWU C;  2GY7 A;  2H43 C;  1N86 C;  2JHL F;  2Z4E B;  2H43 B;  1FZE C;  1RE3 B;  2HPC B;  3H32 C;  2HOD C;  4M7H A;  3H32 B;  2OYI B;  1RF1 C;  3BVH B;  1FZA C;  2XNX C;  1FZA B;  2FFD B;  1Z3U A;  2JHH C;  1FZC C;  2J64 A;  1LWU B;  2J60 A;  2J3G A;  1N86 B;  2J1G A;  2J0Y A;  1FZE B;  4ZFG A;  1FZF C;  2J2P A;  2HOD B;  1FZF B;  4NYT A;  1LTJ C;  1RE4 C;  2J3F D;  1RF1 B;  2J3O A;  1RE4 B;  4M7F A;  3HUS C;  2HLO C;  2XNX B;  2Q9I C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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