1FZFB

Crystal structure of fragment double-d from human fibrin with the peptide ligand gly-his-arg-pro-amide
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 88
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 1998-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzfB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzfB02
4R9JA 3E1IB 3HUSB 1LT9C 4JZCA 1LT9B 1FICA 1FZBC 2WNPF 2J3FD 1FZBB 1FZCC 4JYOX 2HLOC 1FZCB 1RE3C 2Z4EB 2HLOB 2OYIC 1RE3B 2Q9IC 2J3FA 2XNXC 2GY7A 2OYIB 2HPCC 1Z3UA 2Q9IB 2XNXB 2OYHC 1FZAC 3BVHC 2H43C 3GHGC 2J3OA 3H32C 2J0YA 2J61B 2HPCB 4NYTA 1LWUC 2OYHB 2Z4EC 2J1GA 1FZAB 3BVHB 2J61A 2J3UA 2H43B 3H32B 4M7HA 1M1JC 2JHKF 1Z3SA 1LWUB 2JHIF 1RF1C 1M1JB 2FIBA 1RE4C 4R9TA 2D39A 2HODC 2J2PA 1JC9A 1RF1B 2J64A 1RE4B 2J0GA 2HODB 2J3GA 1FZDA 2JHLF 4ZFGA 1FZGC 2J0HA 1LTJC 1FZFC 1N73C 2J60A 1FZGB 1FZEC 2FFDC 1LTJB 1FZFB 2J5ZA 1N73B 1N86C 4M7FA 1FIBA 1FZEB 2FFDB 1FIDA 1RF0C 1N86B 2JHMF 1RF0B 4EPUA 2JHHC 3FIBA 3E1IC 3HUSC
chains in the Genus database with same CATH superfamily
4R9JA 3E1IB 3HUSB 1LT9C 4JZCA 1LT9B 1FICA 1FZBC 2WNPF 2J3FD 1FZBB 1FZCC 4JYOX 2HLOC 1FZCB 1RE3C 2Z4EB 2HLOB 2OYIC 1RE3B 2Q9IC 2J3FA 2XNXC 2GY7A 2OYIB 2HPCC 1Z3UA 2Q9IB 2XNXB 2OYHC 1FZAC 3BVHC 2H43C 3GHGC 2J3OA 3H32C 2J0YA 2J61B 2HPCB 4NYTA 1LWUC 2OYHB 2Z4EC 2J1GA 1FZAB 3BVHB 2J61A 2J3UA 2H43B 3GHGB 3H32B 4M7HA 1M1JC 2JHKF 1Z3SA 1LWUB 2JHIF 1RF1C 1M1JB 2FIBA 1RE4C 4R9TA 2D39A 2HODC 2J2PA 1JC9A 1RF1B 2J64A 1RE4B 2J0GA 2HODB 2J3GA 1FZDA 2JHLF 4ZFGA 1FZGC 2J0HA 1LTJC 1FZFC 1N73C 2J60A 1FZGB 1FZEC 2FFDC 1LTJB 1FZFB 2J5ZA 1N73B 1N86C 4M7FA 1FIBA 1FZEB 2FFDB 1FIDA 1RF0C 1N86B 2JHMF 1RF0B 4EPUA 2JHHC 3FIBA 3E1IC 3HUSC
chains in the Genus database with same CATH topology
4R9JA 3E1IB 3HUSB 1LT9C 4JZCA 1LT9B 1FICA 1FZBC 2WNPF 2J3FD 1FZBB 1FZCC 4JYOX 2HLOC 1FZCB 1RE3C 2Z4EB 2HLOB 2OYIC 1RE3B 2Q9IC 2J3FA 2XNXC 2GY7A 2OYIB 2HPCC 1Z3UA 2Q9IB 2XNXB 2OYHC 1FZAC 3BVHC 2H43C 3GHGC 2J3OA 3H32C 2J0YA 2J61B 2HPCB 4NYTA 1LWUC 2OYHB 2Z4EC 2J1GA 1FZAB 3BVHB 2J61A 2J3UA 2H43B 3H32B 4M7HA 1M1JC 2JHKF 1Z3SA 1LWUB 2JHIF 1RF1C 1M1JB 2FIBA 1RE4C 4R9TA 2D39A 2HODC 2J2PA 1JC9A 1RF1B 2J64A 1RE4B 2J0GA 2HODB 2J3GA 1FZDA 2JHLF 4ZFGA 1FZGC 2J0HA 1LTJC 1FZFC 1N73C 2J60A 1FZGB 1FZEC 2FFDC 1LTJB 1FZFB 2J5ZA 1N73B 1N86C 4M7FA 1FIBA 1FZEB 2FFDB 1FIDA 1RF0C 1N86B 2JHMF 1RF0B 4EPUA 2JHHC 3FIBA 3E1IC 3HUSC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R9J A;  3E1I B;  3HUS B;  1LT9 C;  4JZC A;  1LT9 B;  1FIC A;  1FZB C;  2WNP F;  2J3F D;  1FZB B;  1FZC C;  4JYO X;  2HLO C;  1FZC B;  1RE3 C;  2Z4E B;  2HLO B;  2OYI C;  1RE3 B;  2Q9I C;  2J3F A;  2XNX C;  2GY7 A;  2OYI B;  2HPC C;  1Z3U A;  2Q9I B;  2XNX B;  2OYH C;  1FZA C;  3BVH C;  2H43 C;  3GHG C;  2J3O A;  3H32 C;  2J0Y A;  2J61 B;  2HPC B;  4NYT A;  1LWU C;  2OYH B;  2Z4E C;  2J1G A;  1FZA B;  3BVH B;  2J61 A;  2J3U A;  2H43 B;  3H32 B;  4M7H A;  1M1J C;  2JHK F;  1Z3S A;  1LWU B;  2JHI F;  1RF1 C;  1M1J B;  2FIB A;  1RE4 C;  4R9T A;  2D39 A;  2HOD C;  2J2P A;  1JC9 A;  1RF1 B;  2J64 A;  1RE4 B;  2J0G A;  2HOD B;  2J3G A;  1FZD A;  2JHL F;  4ZFG A;  1FZG C;  2J0H A;  1LTJ C;  1FZF C;  1N73 C;  2J60 A;  1FZG B;  1FZE C;  2FFD C;  1LTJ B;  1FZF B;  2J5Z A;  1N73 B;  1N86 C;  4M7F A;  1FIB A;  1FZE B;  2FFD B;  1FID A;  1RF0 C;  1N86 B;  2JHM F;  1RF0 B;  4EPU A;  2JHH C;  3FIB A;  3E1I C;  3HUS C; 
#chains in the Genus database with same CATH topology
 4R9J A;  3E1I B;  3HUS B;  1LT9 C;  4JZC A;  1LT9 B;  1FIC A;  1FZB C;  2WNP F;  2J3F D;  1FZB B;  1FZC C;  4JYO X;  2HLO C;  1FZC B;  1RE3 C;  2Z4E B;  2HLO B;  2OYI C;  1RE3 B;  2Q9I C;  2J3F A;  2XNX C;  2GY7 A;  2OYI B;  2HPC C;  1Z3U A;  2Q9I B;  2XNX B;  2OYH C;  1FZA C;  3BVH C;  2H43 C;  3GHG C;  2J3O A;  3H32 C;  2J0Y A;  2J61 B;  2HPC B;  4NYT A;  1LWU C;  2OYH B;  2Z4E C;  2J1G A;  1FZA B;  3BVH B;  2J61 A;  2J3U A;  2H43 B;  3GHG B;  3H32 B;  4M7H A;  1M1J C;  2JHK F;  1Z3S A;  1LWU B;  2JHI F;  1RF1 C;  1M1J B;  2FIB A;  1RE4 C;  4R9T A;  2D39 A;  2HOD C;  2J2P A;  1JC9 A;  1RF1 B;  2J64 A;  1RE4 B;  2J0G A;  2HOD B;  2J3G A;  1FZD A;  2JHL F;  4ZFG A;  1FZG C;  2J0H A;  1LTJ C;  1FZF C;  1N73 C;  2J60 A;  1FZG B;  1FZE C;  2FFD C;  1LTJ B;  1FZF B;  2J5Z A;  1N73 B;  1N86 C;  4M7F A;  1FIB A;  1FZE B;  2FFD B;  1FID A;  1RF0 C;  1N86 B;  2JHM F;  1RF0 B;  4EPU A;  2JHH C;  3FIB A;  3E1I C;  3HUS C; 
#chains in the Genus database with same CATH homology
 4R9J A;  3E1I B;  3HUS B;  1LT9 C;  4JZC A;  1LT9 B;  1FIC A;  1FZB C;  2WNP F;  2J3F D;  1FZB B;  1FZC C;  4JYO X;  2HLO C;  1FZC B;  1RE3 C;  2Z4E B;  2HLO B;  2OYI C;  1RE3 B;  2Q9I C;  2J3F A;  2XNX C;  2GY7 A;  2OYI B;  2HPC C;  1Z3U A;  2Q9I B;  2XNX B;  2OYH C;  1FZA C;  3BVH C;  2H43 C;  3GHG C;  2J3O A;  3H32 C;  2J0Y A;  2J61 B;  2HPC B;  4NYT A;  1LWU C;  2OYH B;  2Z4E C;  2J1G A;  1FZA B;  3BVH B;  2J61 A;  2J3U A;  2H43 B;  3H32 B;  4M7H A;  1M1J C;  2JHK F;  1Z3S A;  1LWU B;  2JHI F;  1RF1 C;  1M1J B;  2FIB A;  1RE4 C;  4R9T A;  2D39 A;  2HOD C;  2J2P A;  1JC9 A;  1RF1 B;  2J64 A;  1RE4 B;  2J0G A;  2HOD B;  2J3G A;  1FZD A;  2JHL F;  4ZFG A;  1FZG C;  2J0H A;  1LTJ C;  1FZF C;  1N73 C;  2J60 A;  1FZG B;  1FZE C;  2FFD C;  1LTJ B;  1FZF B;  2J5Z A;  1N73 B;  1N86 C;  4M7F A;  1FIB A;  1FZE B;  2FFD B;  1FID A;  1RF0 C;  1N86 B;  2JHM F;  1RF0 B;  4EPU A;  2JHH C;  3FIB A;  3E1I C;  3HUS C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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