1FZGB

Crystal structure of fragment d from human fibrinogen with the peptide ligand gly-his-arg-pro-amide
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 92
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 1999-01-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzgB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzgB02
4R9TA 3BVHB 2JHLF 3FIBA 2FIBA 2HODB 2J0HA 2HPCB 3E1IB 2J0YA 1FIDA 2Q9IC 2JHIF 1FZCB 2HODC 2Z4EC 2HPCC 2J3FA 3E1IC 2OYHB 1FZBC 1N73C 4M7FA 4ZFGA 2Q9IB 4R9JA 1LT9C 1FZCC 2D39A 1Z3UA 2Z4EB 1LTJC 1FZFB 1FZGB 2JHHC 2OYHC 2XNXC 2H43C 1FZBB 1N73B 1LT9B 1FZEC 1RE4C 1LTJB 1FZFC 1FZGC 1LWUC 1FIBA 4NYTA 1M1JC 2WNPF 2XNXB 2J60A 2H43B 1FICA 2JHMF 2J2PA 1FZEB 1RE4B 2J3FD 2J3UA 1LWUB 2HLOC 1M1JB 1RE3B 2FFDB 1N86C 1Z3SA 1RF0B 3HUSC 2J1GA 2HLOB 2J3GA 1FZAC 1RE3C 2FFDC 1N86B 2J61B 3H32C 1RF0C 3GHGC 3HUSB 2J0GA 2JHKF 1RF1C 4JZCA 2J61A 4JYOX 1JC9A 4M7HA 2OYIB 2J64A 3BVHC 1FZAB 2J5ZA 3H32B 4EPUA 2J3OA 1RF1B 2GY7A 2OYIC 1FZDA
chains in the Genus database with same CATH superfamily
4R9TA 3BVHB 2JHLF 3FIBA 2FIBA 2HODB 2J0HA 2HPCB 3E1IB 2J0YA 1FIDA 2Q9IC 2JHIF 1FZCB 2HODC 2Z4EC 2HPCC 2J3FA 3E1IC 2OYHB 1FZBC 1N73C 4M7FA 4ZFGA 2Q9IB 4R9JA 1LT9C 1FZCC 2D39A 1Z3UA 2Z4EB 1LTJC 1FZFB 1FZGB 2JHHC 2OYHC 2XNXC 2H43C 1FZBB 1N73B 1LT9B 1FZEC 1RE4C 1LTJB 1FZFC 1FZGC 1LWUC 1FIBA 4NYTA 1M1JC 2WNPF 2XNXB 2J60A 2H43B 1FICA 2JHMF 2J2PA 1FZEB 1RE4B 2J3FD 2J3UA 1LWUB 2HLOC 1M1JB 1RE3B 2FFDB 1N86C 1Z3SA 1RF0B 3HUSC 3GHGB 2J1GA 2HLOB 2J3GA 1FZAC 1RE3C 2FFDC 1N86B 2J61B 3H32C 1RF0C 3GHGC 3HUSB 2J0GA 2JHKF 1RF1C 4JZCA 2J61A 4JYOX 1JC9A 4M7HA 2OYIB 2J64A 3BVHC 1FZAB 2J5ZA 3H32B 4EPUA 2J3OA 1RF1B 2GY7A 2OYIC 1FZDA
chains in the Genus database with same CATH topology
4R9TA 3BVHB 2JHLF 3FIBA 2FIBA 2HODB 2J0HA 2HPCB 3E1IB 2J0YA 1FIDA 2Q9IC 2JHIF 1FZCB 2HODC 2Z4EC 2HPCC 2J3FA 3E1IC 2OYHB 1FZBC 1N73C 4M7FA 4ZFGA 2Q9IB 4R9JA 1LT9C 1FZCC 2D39A 1Z3UA 2Z4EB 1LTJC 1FZFB 1FZGB 2JHHC 2OYHC 2XNXC 2H43C 1FZBB 1N73B 1LT9B 1FZEC 1RE4C 1LTJB 1FZFC 1FZGC 1LWUC 1FIBA 4NYTA 1M1JC 2WNPF 2XNXB 2J60A 2H43B 1FICA 2JHMF 2J2PA 1FZEB 1RE4B 2J3FD 2J3UA 1LWUB 2HLOC 1M1JB 1RE3B 2FFDB 1N86C 1Z3SA 1RF0B 3HUSC 2J1GA 2HLOB 2J3GA 1FZAC 1RE3C 2FFDC 1N86B 2J61B 3H32C 1RF0C 3GHGC 3HUSB 2J0GA 2JHKF 1RF1C 4JZCA 2J61A 4JYOX 1JC9A 4M7HA 2OYIB 2J64A 3BVHC 1FZAB 2J5ZA 3H32B 4EPUA 2J3OA 1RF1B 2GY7A 2OYIC 1FZDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R9T A;  3BVH B;  2JHL F;  3FIB A;  2FIB A;  2HOD B;  2J0H A;  2HPC B;  3E1I B;  2J0Y A;  1FID A;  2Q9I C;  2JHI F;  1FZC B;  2HOD C;  2Z4E C;  2HPC C;  2J3F A;  3E1I C;  2OYH B;  1FZB C;  1N73 C;  4M7F A;  4ZFG A;  2Q9I B;  4R9J A;  1LT9 C;  1FZC C;  2D39 A;  1Z3U A;  2Z4E B;  1LTJ C;  1FZF B;  1FZG B;  2JHH C;  2OYH C;  2XNX C;  2H43 C;  1FZB B;  1N73 B;  1LT9 B;  1FZE C;  1RE4 C;  1LTJ B;  1FZF C;  1FZG C;  1LWU C;  1FIB A;  4NYT A;  1M1J C;  2WNP F;  2XNX B;  2J60 A;  2H43 B;  1FIC A;  2JHM F;  2J2P A;  1FZE B;  1RE4 B;  2J3F D;  2J3U A;  1LWU B;  2HLO C;  1M1J B;  1RE3 B;  2FFD B;  1N86 C;  1Z3S A;  1RF0 B;  3HUS C;  2J1G A;  2HLO B;  2J3G A;  1FZA C;  1RE3 C;  2FFD C;  1N86 B;  2J61 B;  3H32 C;  1RF0 C;  3GHG C;  3HUS B;  2J0G A;  2JHK F;  1RF1 C;  4JZC A;  2J61 A;  4JYO X;  1JC9 A;  4M7H A;  2OYI B;  2J64 A;  3BVH C;  1FZA B;  2J5Z A;  3H32 B;  4EPU A;  2J3O A;  1RF1 B;  2GY7 A;  2OYI C;  1FZD A; 
#chains in the Genus database with same CATH topology
 4R9T A;  3BVH B;  2JHL F;  3FIB A;  2FIB A;  2HOD B;  2J0H A;  2HPC B;  3E1I B;  2J0Y A;  1FID A;  2Q9I C;  2JHI F;  1FZC B;  2HOD C;  2Z4E C;  2HPC C;  2J3F A;  3E1I C;  2OYH B;  1FZB C;  1N73 C;  4M7F A;  4ZFG A;  2Q9I B;  4R9J A;  1LT9 C;  1FZC C;  2D39 A;  1Z3U A;  2Z4E B;  1LTJ C;  1FZF B;  1FZG B;  2JHH C;  2OYH C;  2XNX C;  2H43 C;  1FZB B;  1N73 B;  1LT9 B;  1FZE C;  1RE4 C;  1LTJ B;  1FZF C;  1FZG C;  1LWU C;  1FIB A;  4NYT A;  1M1J C;  2WNP F;  2XNX B;  2J60 A;  2H43 B;  1FIC A;  2JHM F;  2J2P A;  1FZE B;  1RE4 B;  2J3F D;  2J3U A;  1LWU B;  2HLO C;  1M1J B;  1RE3 B;  2FFD B;  1N86 C;  1Z3S A;  1RF0 B;  3HUS C;  3GHG B;  2J1G A;  2HLO B;  2J3G A;  1FZA C;  1RE3 C;  2FFD C;  1N86 B;  2J61 B;  3H32 C;  1RF0 C;  3GHG C;  3HUS B;  2J0G A;  2JHK F;  1RF1 C;  4JZC A;  2J61 A;  4JYO X;  1JC9 A;  4M7H A;  2OYI B;  2J64 A;  3BVH C;  1FZA B;  2J5Z A;  3H32 B;  4EPU A;  2J3O A;  1RF1 B;  2GY7 A;  2OYI C;  1FZD A; 
#chains in the Genus database with same CATH homology
 4R9T A;  3BVH B;  2JHL F;  3FIB A;  2FIB A;  2HOD B;  2J0H A;  2HPC B;  3E1I B;  2J0Y A;  1FID A;  2Q9I C;  2JHI F;  1FZC B;  2HOD C;  2Z4E C;  2HPC C;  2J3F A;  3E1I C;  2OYH B;  1FZB C;  1N73 C;  4M7F A;  4ZFG A;  2Q9I B;  4R9J A;  1LT9 C;  1FZC C;  2D39 A;  1Z3U A;  2Z4E B;  1LTJ C;  1FZF B;  1FZG B;  2JHH C;  2OYH C;  2XNX C;  2H43 C;  1FZB B;  1N73 B;  1LT9 B;  1FZE C;  1RE4 C;  1LTJ B;  1FZF C;  1FZG C;  1LWU C;  1FIB A;  4NYT A;  1M1J C;  2WNP F;  2XNX B;  2J60 A;  2H43 B;  1FIC A;  2JHM F;  2J2P A;  1FZE B;  1RE4 B;  2J3F D;  2J3U A;  1LWU B;  2HLO C;  1M1J B;  1RE3 B;  2FFD B;  1N86 C;  1Z3S A;  1RF0 B;  3HUS C;  2J1G A;  2HLO B;  2J3G A;  1FZA C;  1RE3 C;  2FFD C;  1N86 B;  2J61 B;  3H32 C;  1RF0 C;  3GHG C;  3HUS B;  2J0G A;  2JHK F;  1RF1 C;  4JZC A;  2J61 A;  4JYO X;  1JC9 A;  4M7H A;  2OYI B;  2J64 A;  3BVH C;  1FZA B;  2J5Z A;  3H32 B;  4EPU A;  2J3O A;  1RF1 B;  2GY7 A;  2OYI C;  1FZD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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