1FZGC

Crystal structure of fragment d from human fibrinogen with the peptide ligand gly-his-arg-pro-amide
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 87
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 1999-01-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzgC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzgC02
1N73B 1FZDA 1FIDA 2J3FD 2XNXC 1LT9B 3BVHC 3HUSC 1LTJC 2J3OA 4NYTA 1FZAB 1FZFC 3E1IC 2J3UA 1M1JC 3H32C 1FIBA 1JC9A 2J61B 2Z4EB 1RF0B 1FZGC 4ZFGA 2J3GA 3GHGC 2J2PA 1RE4B 4JYOX 1FICA 1FZFB 1M1JB 2J5ZA 1FZEC 1N86C 2HODC 1RF1C 2D39A 2Q9IC 2JHKF 2J0YA 2HPCC 2OYIC 2FFDC 2JHHC 2XNXB 1FZEB 1FZBC 1RF1B 1RE3C 3BVHB 3HUSB 2J1GA 1LTJB 2OYIB 2J60A 3FIBA 2J3FA 3E1IB 1FZBB 4M7HA 2J64A 3H32B 1FZCC 4JZCA 2OYHC 2FIBA 1FZGB 2JHLF 2J0GA 1N73C 2WNPF 1FZCB 2JHIF 1N86B 2HODB 1Z3UA 4M7FA 2Q9IB 2GY7A 1FZAC 2HLOC 2J61A 2HPCB 2FFDB 2Z4EC 1LWUC 1RE3B 1RF0C 4EPUA 2H43C 2J0HA 4R9TA 1RE4C 2HLOB 4R9JA 2JHMF 1Z3SA 1LWUB 1LT9C 2H43B 2OYHB
chains in the Genus database with same CATH superfamily
1N73B 1FZDA 1FIDA 2J3FD 2XNXC 1LT9B 3BVHC 3HUSC 1LTJC 2J3OA 4NYTA 1FZAB 1FZFC 3E1IC 2J3UA 1M1JC 3H32C 1FIBA 1JC9A 2J61B 2Z4EB 1RF0B 1FZGC 4ZFGA 2J3GA 3GHGC 2J2PA 1RE4B 4JYOX 1FICA 1FZFB 1M1JB 2J5ZA 1FZEC 1N86C 2HODC 1RF1C 2D39A 2Q9IC 2JHKF 2J0YA 2HPCC 2OYIC 2FFDC 2JHHC 2XNXB 1FZEB 1FZBC 1RF1B 1RE3C 3BVHB 3HUSB 2J1GA 1LTJB 2OYIB 2J60A 3FIBA 2J3FA 3E1IB 1FZBB 4M7HA 2J64A 3H32B 1FZCC 4JZCA 2OYHC 2FIBA 1FZGB 2JHLF 3GHGB 2J0GA 1N73C 2WNPF 1FZCB 2JHIF 1N86B 2HODB 1Z3UA 4M7FA 2Q9IB 2GY7A 1FZAC 2HLOC 2J61A 2HPCB 2FFDB 2Z4EC 1LWUC 1RE3B 1RF0C 4EPUA 2H43C 2J0HA 4R9TA 1RE4C 2HLOB 4R9JA 2JHMF 1Z3SA 1LWUB 1LT9C 2H43B 2OYHB
chains in the Genus database with same CATH topology
1N73B 1FZDA 1FIDA 2J3FD 2XNXC 1LT9B 3BVHC 3HUSC 1LTJC 2J3OA 4NYTA 1FZAB 1FZFC 3E1IC 2J3UA 1M1JC 3H32C 1FIBA 1JC9A 2J61B 2Z4EB 1RF0B 1FZGC 4ZFGA 2J3GA 3GHGC 2J2PA 1RE4B 4JYOX 1FICA 1FZFB 1M1JB 2J5ZA 1FZEC 1N86C 2HODC 1RF1C 2D39A 2Q9IC 2JHKF 2J0YA 2HPCC 2OYIC 2FFDC 2JHHC 2XNXB 1FZEB 1FZBC 1RF1B 1RE3C 3BVHB 3HUSB 2J1GA 1LTJB 2OYIB 2J60A 3FIBA 2J3FA 3E1IB 1FZBB 4M7HA 2J64A 3H32B 1FZCC 4JZCA 2OYHC 2FIBA 1FZGB 2JHLF 2J0GA 1N73C 2WNPF 1FZCB 2JHIF 1N86B 2HODB 1Z3UA 4M7FA 2Q9IB 2GY7A 1FZAC 2HLOC 2J61A 2HPCB 2FFDB 2Z4EC 1LWUC 1RE3B 1RF0C 4EPUA 2H43C 2J0HA 4R9TA 1RE4C 2HLOB 4R9JA 2JHMF 1Z3SA 1LWUB 1LT9C 2H43B 2OYHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N73 B;  1FZD A;  1FID A;  2J3F D;  2XNX C;  1LT9 B;  3BVH C;  3HUS C;  1LTJ C;  2J3O A;  4NYT A;  1FZA B;  1FZF C;  3E1I C;  2J3U A;  1M1J C;  3H32 C;  1FIB A;  1JC9 A;  2J61 B;  2Z4E B;  1RF0 B;  1FZG C;  4ZFG A;  2J3G A;  3GHG C;  2J2P A;  1RE4 B;  4JYO X;  1FIC A;  1FZF B;  1M1J B;  2J5Z A;  1FZE C;  1N86 C;  2HOD C;  1RF1 C;  2D39 A;  2Q9I C;  2JHK F;  2J0Y A;  2HPC C;  2OYI C;  2FFD C;  2JHH C;  2XNX B;  1FZE B;  1FZB C;  1RF1 B;  1RE3 C;  3BVH B;  3HUS B;  2J1G A;  1LTJ B;  2OYI B;  2J60 A;  3FIB A;  2J3F A;  3E1I B;  1FZB B;  4M7H A;  2J64 A;  3H32 B;  1FZC C;  4JZC A;  2OYH C;  2FIB A;  1FZG B;  2JHL F;  2J0G A;  1N73 C;  2WNP F;  1FZC B;  2JHI F;  1N86 B;  2HOD B;  1Z3U A;  4M7F A;  2Q9I B;  2GY7 A;  1FZA C;  2HLO C;  2J61 A;  2HPC B;  2FFD B;  2Z4E C;  1LWU C;  1RE3 B;  1RF0 C;  4EPU A;  2H43 C;  2J0H A;  4R9T A;  1RE4 C;  2HLO B;  4R9J A;  2JHM F;  1Z3S A;  1LWU B;  1LT9 C;  2H43 B;  2OYH B; 
#chains in the Genus database with same CATH topology
 1N73 B;  1FZD A;  1FID A;  2J3F D;  2XNX C;  1LT9 B;  3BVH C;  3HUS C;  1LTJ C;  2J3O A;  4NYT A;  1FZA B;  1FZF C;  3E1I C;  2J3U A;  1M1J C;  3H32 C;  1FIB A;  1JC9 A;  2J61 B;  2Z4E B;  1RF0 B;  1FZG C;  4ZFG A;  2J3G A;  3GHG C;  2J2P A;  1RE4 B;  4JYO X;  1FIC A;  1FZF B;  1M1J B;  2J5Z A;  1FZE C;  1N86 C;  2HOD C;  1RF1 C;  2D39 A;  2Q9I C;  2JHK F;  2J0Y A;  2HPC C;  2OYI C;  2FFD C;  2JHH C;  2XNX B;  1FZE B;  1FZB C;  1RF1 B;  1RE3 C;  3BVH B;  3HUS B;  2J1G A;  1LTJ B;  2OYI B;  2J60 A;  3FIB A;  2J3F A;  3E1I B;  1FZB B;  4M7H A;  2J64 A;  3H32 B;  1FZC C;  4JZC A;  2OYH C;  2FIB A;  1FZG B;  2JHL F;  3GHG B;  2J0G A;  1N73 C;  2WNP F;  1FZC B;  2JHI F;  1N86 B;  2HOD B;  1Z3U A;  4M7F A;  2Q9I B;  2GY7 A;  1FZA C;  2HLO C;  2J61 A;  2HPC B;  2FFD B;  2Z4E C;  1LWU C;  1RE3 B;  1RF0 C;  4EPU A;  2H43 C;  2J0H A;  4R9T A;  1RE4 C;  2HLO B;  4R9J A;  2JHM F;  1Z3S A;  1LWU B;  1LT9 C;  2H43 B;  2OYH B; 
#chains in the Genus database with same CATH homology
 1N73 B;  1FZD A;  1FID A;  2J3F D;  2XNX C;  1LT9 B;  3BVH C;  3HUS C;  1LTJ C;  2J3O A;  4NYT A;  1FZA B;  1FZF C;  3E1I C;  2J3U A;  1M1J C;  3H32 C;  1FIB A;  1JC9 A;  2J61 B;  2Z4E B;  1RF0 B;  1FZG C;  4ZFG A;  2J3G A;  3GHG C;  2J2P A;  1RE4 B;  4JYO X;  1FIC A;  1FZF B;  1M1J B;  2J5Z A;  1FZE C;  1N86 C;  2HOD C;  1RF1 C;  2D39 A;  2Q9I C;  2JHK F;  2J0Y A;  2HPC C;  2OYI C;  2FFD C;  2JHH C;  2XNX B;  1FZE B;  1FZB C;  1RF1 B;  1RE3 C;  3BVH B;  3HUS B;  2J1G A;  1LTJ B;  2OYI B;  2J60 A;  3FIB A;  2J3F A;  3E1I B;  1FZB B;  4M7H A;  2J64 A;  3H32 B;  1FZC C;  4JZC A;  2OYH C;  2FIB A;  1FZG B;  2JHL F;  2J0G A;  1N73 C;  2WNP F;  1FZC B;  2JHI F;  1N86 B;  2HOD B;  1Z3U A;  4M7F A;  2Q9I B;  2GY7 A;  1FZA C;  2HLO C;  2J61 A;  2HPC B;  2FFD B;  2Z4E C;  1LWU C;  1RE3 B;  1RF0 C;  4EPU A;  2H43 C;  2J0H A;  4R9T A;  1RE4 C;  2HLO B;  4R9J A;  2JHM F;  1Z3S A;  1LWU B;  1LT9 C;  2H43 B;  2OYH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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