2GY7A

Angiopoietin-2/tie2 complex crystal structure
Total Genus 46

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
216
structure length
216
Chain Sequence
EFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
O8 (44-102)O9 (211-220)EMPTYUpdating...
connected with : NaN
molecule tags Signaling protein
source organism Homo sapiens
publication title Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
pubmed doi rcsb
molecule keywords Angiopoietin-2
total genus 46
structure length 216
sequence length 216
ec nomenclature
pdb deposition date 2006-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2gy7A01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2gy7A02
2J5ZA 2J1GA 1N86B 2FFDB 4JYOX 4NYTA 2J3GA 1RE3B 3BVHC 1FZEB 2Z4EC 1N86C 2HLOC 1N73C 2FIBA 3H32B 2JHMF 1FZDA 2H43B 1RE3C 1Z3UA 1FZEC 3HUSC 1RF0C 4ZFGA 4EPUA 2J3UA 2OYIC 1Z3SA 1FZCB 1FZFB 2Q9IB 2J3FD 2FFDC 1LWUB 1LT9B 4M7FA 1FZCC 1FZGB 1M1JB 3E1IB 1FZBB 3H32C 2J3FA 2J60A 2H43C 1FZAB 2HODB 2OYHB 3FIBA 4JZCA 1LTJB 2WNPF 1RF1B 2J0YA 2HODC 2JHKF 3GHGC 2JHHC 1FZFC 2XNXB 2Q9IC 3BVHB 4M7HA 2Z4EB 1FIDA 2HLOB 1N73B 2J64A 2J61A 1LWUC 4R9TA 1LT9C 1RE4B 4R9JA 2XNXC 1FZGC 2J0HA 2JHIF 2J3OA 1M1JC 2D39A 3HUSB 3E1IC 2GY7A 1FZBC 2HPCB 1JC9A 1RF0B 1FIBA 1FZAC 2J61B 1RE4C 2OYHC 2J0GA 2J2PA 1FICA 1LTJC 2OYIB 2JHLF 1RF1C 2HPCC
chains in the Genus database with same CATH superfamily
2J5ZA 2J1GA 1N86B 2FFDB 4JYOX 4NYTA 2J3GA 1RE3B 3BVHC 1FZEB 2Z4EC 1N86C 2HLOC 1N73C 2FIBA 3H32B 2JHMF 1FZDA 2H43B 1RE3C 1Z3UA 1FZEC 3HUSC 1RF0C 4ZFGA 4EPUA 2J3UA 2OYIC 1Z3SA 1FZCB 1FZFB 2Q9IB 2J3FD 2FFDC 1LWUB 1LT9B 4M7FA 1FZCC 1FZGB 1M1JB 3E1IB 1FZBB 3H32C 2J3FA 2J60A 2H43C 1FZAB 2HODB 2OYHB 3FIBA 4JZCA 1LTJB 3GHGB 2WNPF 1RF1B 2J0YA 2HODC 2JHKF 3GHGC 2JHHC 1FZFC 2XNXB 2Q9IC 3BVHB 4M7HA 2Z4EB 1FIDA 2HLOB 1N73B 2J64A 2J61A 1LWUC 4R9TA 1LT9C 1RE4B 4R9JA 2XNXC 1FZGC 2J0HA 2JHIF 2J3OA 1M1JC 2D39A 3HUSB 3E1IC 2GY7A 1FZBC 2HPCB 1JC9A 1RF0B 1FIBA 1FZAC 2J61B 1RE4C 2OYHC 2J0GA 2J2PA 1FICA 1LTJC 2OYIB 2JHLF 1RF1C 2HPCC
chains in the Genus database with same CATH topology
2J5ZA 2J1GA 1N86B 2FFDB 4JYOX 4NYTA 2J3GA 1RE3B 3BVHC 1FZEB 2Z4EC 1N86C 2HLOC 1N73C 2FIBA 3H32B 2JHMF 1FZDA 2H43B 1RE3C 1Z3UA 1FZEC 3HUSC 1RF0C 4ZFGA 4EPUA 2J3UA 2OYIC 1Z3SA 1FZCB 1FZFB 2Q9IB 2J3FD 2FFDC 1LWUB 1LT9B 4M7FA 1FZCC 1FZGB 1M1JB 3E1IB 1FZBB 3H32C 2J3FA 2J60A 2H43C 1FZAB 2HODB 2OYHB 3FIBA 4JZCA 1LTJB 2WNPF 1RF1B 2J0YA 2HODC 2JHKF 3GHGC 2JHHC 1FZFC 2XNXB 2Q9IC 3BVHB 4M7HA 2Z4EB 1FIDA 2HLOB 1N73B 2J64A 2J61A 1LWUC 4R9TA 1LT9C 1RE4B 4R9JA 2XNXC 1FZGC 2J0HA 2JHIF 2J3OA 1M1JC 2D39A 3HUSB 3E1IC 2GY7A 1FZBC 2HPCB 1JC9A 1RF0B 1FIBA 1FZAC 2J61B 1RE4C 2OYHC 2J0GA 2J2PA 1FICA 1LTJC 2OYIB 2JHLF 1RF1C 2HPCC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2J5Z A;  2J1G A;  1N86 B;  2FFD B;  4JYO X;  4NYT A;  2J3G A;  1RE3 B;  3BVH C;  1FZE B;  2Z4E C;  1N86 C;  2HLO C;  1N73 C;  2FIB A;  3H32 B;  2JHM F;  1FZD A;  2H43 B;  1RE3 C;  1Z3U A;  1FZE C;  3HUS C;  1RF0 C;  4ZFG A;  4EPU A;  2J3U A;  2OYI C;  1Z3S A;  1FZC B;  1FZF B;  2Q9I B;  2J3F D;  2FFD C;  1LWU B;  1LT9 B;  4M7F A;  1FZC C;  1FZG B;  1M1J B;  3E1I B;  1FZB B;  3H32 C;  2J3F A;  2J60 A;  2H43 C;  1FZA B;  2HOD B;  2OYH B;  3FIB A;  4JZC A;  1LTJ B;  2WNP F;  1RF1 B;  2J0Y A;  2HOD C;  2JHK F;  3GHG C;  2JHH C;  1FZF C;  2XNX B;  2Q9I C;  3BVH B;  4M7H A;  2Z4E B;  1FID A;  2HLO B;  1N73 B;  2J64 A;  2J61 A;  1LWU C;  4R9T A;  1LT9 C;  1RE4 B;  4R9J A;  2XNX C;  1FZG C;  2J0H A;  2JHI F;  2J3O A;  1M1J C;  2D39 A;  3HUS B;  3E1I C;  2GY7 A;  1FZB C;  2HPC B;  1JC9 A;  1RF0 B;  1FIB A;  1FZA C;  2J61 B;  1RE4 C;  2OYH C;  2J0G A;  2J2P A;  1FIC A;  1LTJ C;  2OYI B;  2JHL F;  1RF1 C;  2HPC C; 
#chains in the Genus database with same CATH topology
 2J5Z A;  2J1G A;  1N86 B;  2FFD B;  4JYO X;  4NYT A;  2J3G A;  1RE3 B;  3BVH C;  1FZE B;  2Z4E C;  1N86 C;  2HLO C;  1N73 C;  2FIB A;  3H32 B;  2JHM F;  1FZD A;  2H43 B;  1RE3 C;  1Z3U A;  1FZE C;  3HUS C;  1RF0 C;  4ZFG A;  4EPU A;  2J3U A;  2OYI C;  1Z3S A;  1FZC B;  1FZF B;  2Q9I B;  2J3F D;  2FFD C;  1LWU B;  1LT9 B;  4M7F A;  1FZC C;  1FZG B;  1M1J B;  3E1I B;  1FZB B;  3H32 C;  2J3F A;  2J60 A;  2H43 C;  1FZA B;  2HOD B;  2OYH B;  3FIB A;  4JZC A;  1LTJ B;  3GHG B;  2WNP F;  1RF1 B;  2J0Y A;  2HOD C;  2JHK F;  3GHG C;  2JHH C;  1FZF C;  2XNX B;  2Q9I C;  3BVH B;  4M7H A;  2Z4E B;  1FID A;  2HLO B;  1N73 B;  2J64 A;  2J61 A;  1LWU C;  4R9T A;  1LT9 C;  1RE4 B;  4R9J A;  2XNX C;  1FZG C;  2J0H A;  2JHI F;  2J3O A;  1M1J C;  2D39 A;  3HUS B;  3E1I C;  2GY7 A;  1FZB C;  2HPC B;  1JC9 A;  1RF0 B;  1FIB A;  1FZA C;  2J61 B;  1RE4 C;  2OYH C;  2J0G A;  2J2P A;  1FIC A;  1LTJ C;  2OYI B;  2JHL F;  1RF1 C;  2HPC C; 
#chains in the Genus database with same CATH homology
 2J5Z A;  2J1G A;  1N86 B;  2FFD B;  4JYO X;  4NYT A;  2J3G A;  1RE3 B;  3BVH C;  1FZE B;  2Z4E C;  1N86 C;  2HLO C;  1N73 C;  2FIB A;  3H32 B;  2JHM F;  1FZD A;  2H43 B;  1RE3 C;  1Z3U A;  1FZE C;  3HUS C;  1RF0 C;  4ZFG A;  4EPU A;  2J3U A;  2OYI C;  1Z3S A;  1FZC B;  1FZF B;  2Q9I B;  2J3F D;  2FFD C;  1LWU B;  1LT9 B;  4M7F A;  1FZC C;  1FZG B;  1M1J B;  3E1I B;  1FZB B;  3H32 C;  2J3F A;  2J60 A;  2H43 C;  1FZA B;  2HOD B;  2OYH B;  3FIB A;  4JZC A;  1LTJ B;  2WNP F;  1RF1 B;  2J0Y A;  2HOD C;  2JHK F;  3GHG C;  2JHH C;  1FZF C;  2XNX B;  2Q9I C;  3BVH B;  4M7H A;  2Z4E B;  1FID A;  2HLO B;  1N73 B;  2J64 A;  2J61 A;  1LWU C;  4R9T A;  1LT9 C;  1RE4 B;  4R9J A;  2XNX C;  1FZG C;  2J0H A;  2JHI F;  2J3O A;  1M1J C;  2D39 A;  3HUS B;  3E1I C;  2GY7 A;  1FZB C;  2HPC B;  1JC9 A;  1RF0 B;  1FIB A;  1FZA C;  2J61 B;  1RE4 C;  2OYH C;  2J0G A;  2J2P A;  1FIC A;  1LTJ C;  2OYI B;  2JHL F;  1RF1 C;  2HPC C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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