2H43B

Crystal structure of human fragment d complexed with ala-his-arg-pro-amide
Total Genus 88
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
302
structure length
302
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Differences in Binding Specificity for the Homologous gamma- and beta-Chain "Holes" on Fibrinogen: Exclusive Binding of Ala-His-Arg-Pro-amide by the beta-Chain Hole.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 88
structure length 302
sequence length 302
chains with identical sequence E
ec nomenclature
pdb deposition date 2006-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2h43B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2h43B02
2WNPF 2JHMF 1FIBA 2OYIB 1RE4C 1N73C 1Z3SA 2J3OA 1M1JC 2J0GA 2JHKF 1RF1C 2J2PA 1FIDA 2J3FA 1JC9A 1LT9C 2J60A 1FZFC 1RE4B 1N73B 1LTJC 3HUSC 2XNXC 1RF0C 1RF1B 2OYHC 1Z3UA 3H32B 2J3UA 1FZCC 1FZAB 1LT9B 3GHGC 3E1IC 1FZFB 4M7FA 4EPUA 3BVHC 2Q9IC 2JHHC 3H32C 4R9TA 1FZAC 4R9JA 2FIBA 1LTJB 2HLOB 1FZGC 2FFDC 3HUSB 2J0YA 2XNXB 1RF0B 2J1GA 2JHLF 2OYHB 1FICA 1FZCB 2D39A 2HLOC 3E1IB 4M7HA 1FZBC 3BVHB 2Q9IB 2J5ZA 2J61B 2H43C 4JZCA 1FZGB 2FFDB 2HPCC 4ZFGA 2JHIF 1N86C 2J3GA 2Z4EC 1FZBB 1RE3C 1FZEC 2HODC 4NYTA 2H43B 2GY7A 2J64A 2HPCB 1N86B 2OYIC 1LWUB 2J61A 2Z4EB 2J3FD 3FIBA 4JYOX 1RE3B 1FZEB 2HODB 1LWUC 2J0HA 1FZDA 1M1JB
chains in the Genus database with same CATH superfamily
2WNPF 2JHMF 1FIBA 2OYIB 1RE4C 1N73C 1Z3SA 2J3OA 1M1JC 2J0GA 2JHKF 1RF1C 2J2PA 1FIDA 2J3FA 1JC9A 1LT9C 2J60A 1FZFC 1RE4B 1N73B 1LTJC 3HUSC 2XNXC 1RF0C 1RF1B 2OYHC 1Z3UA 3H32B 2J3UA 1FZCC 1FZAB 1LT9B 3GHGC 3E1IC 1FZFB 4M7FA 4EPUA 3BVHC 2Q9IC 2JHHC 3H32C 4R9TA 1FZAC 4R9JA 2FIBA 1LTJB 2HLOB 1FZGC 2FFDC 3HUSB 2J0YA 2XNXB 1RF0B 2J1GA 2JHLF 2OYHB 1FICA 1FZCB 2D39A 2HLOC 3GHGB 3E1IB 4M7HA 1FZBC 3BVHB 2Q9IB 2J5ZA 2J61B 2H43C 4JZCA 1FZGB 2FFDB 2HPCC 4ZFGA 2JHIF 1N86C 2J3GA 2Z4EC 1FZBB 1RE3C 1FZEC 2HODC 4NYTA 2H43B 2GY7A 2J64A 2HPCB 1N86B 2OYIC 1LWUB 2J61A 2Z4EB 2J3FD 3FIBA 4JYOX 1RE3B 1FZEB 2HODB 1LWUC 2J0HA 1FZDA 1M1JB
chains in the Genus database with same CATH topology
2WNPF 2JHMF 1FIBA 2OYIB 1RE4C 1N73C 1Z3SA 2J3OA 1M1JC 2J0GA 2JHKF 1RF1C 2J2PA 1FIDA 2J3FA 1JC9A 1LT9C 2J60A 1FZFC 1RE4B 1N73B 1LTJC 3HUSC 2XNXC 1RF0C 1RF1B 2OYHC 1Z3UA 3H32B 2J3UA 1FZCC 1FZAB 1LT9B 3GHGC 3E1IC 1FZFB 4M7FA 4EPUA 3BVHC 2Q9IC 2JHHC 3H32C 4R9TA 1FZAC 4R9JA 2FIBA 1LTJB 2HLOB 1FZGC 2FFDC 3HUSB 2J0YA 2XNXB 1RF0B 2J1GA 2JHLF 2OYHB 1FICA 1FZCB 2D39A 2HLOC 3E1IB 4M7HA 1FZBC 3BVHB 2Q9IB 2J5ZA 2J61B 2H43C 4JZCA 1FZGB 2FFDB 2HPCC 4ZFGA 2JHIF 1N86C 2J3GA 2Z4EC 1FZBB 1RE3C 1FZEC 2HODC 4NYTA 2H43B 2GY7A 2J64A 2HPCB 1N86B 2OYIC 1LWUB 2J61A 2Z4EB 2J3FD 3FIBA 4JYOX 1RE3B 1FZEB 2HODB 1LWUC 2J0HA 1FZDA 1M1JB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WNP F;  2JHM F;  1FIB A;  2OYI B;  1RE4 C;  1N73 C;  1Z3S A;  2J3O A;  1M1J C;  2J0G A;  2JHK F;  1RF1 C;  2J2P A;  1FID A;  2J3F A;  1JC9 A;  1LT9 C;  2J60 A;  1FZF C;  1RE4 B;  1N73 B;  1LTJ C;  3HUS C;  2XNX C;  1RF0 C;  1RF1 B;  2OYH C;  1Z3U A;  3H32 B;  2J3U A;  1FZC C;  1FZA B;  1LT9 B;  3GHG C;  3E1I C;  1FZF B;  4M7F A;  4EPU A;  3BVH C;  2Q9I C;  2JHH C;  3H32 C;  4R9T A;  1FZA C;  4R9J A;  2FIB A;  1LTJ B;  2HLO B;  1FZG C;  2FFD C;  3HUS B;  2J0Y A;  2XNX B;  1RF0 B;  2J1G A;  2JHL F;  2OYH B;  1FIC A;  1FZC B;  2D39 A;  2HLO C;  3E1I B;  4M7H A;  1FZB C;  3BVH B;  2Q9I B;  2J5Z A;  2J61 B;  2H43 C;  4JZC A;  1FZG B;  2FFD B;  2HPC C;  4ZFG A;  2JHI F;  1N86 C;  2J3G A;  2Z4E C;  1FZB B;  1RE3 C;  1FZE C;  2HOD C;  4NYT A;  2H43 B;  2GY7 A;  2J64 A;  2HPC B;  1N86 B;  2OYI C;  1LWU B;  2J61 A;  2Z4E B;  2J3F D;  3FIB A;  4JYO X;  1RE3 B;  1FZE B;  2HOD B;  1LWU C;  2J0H A;  1FZD A;  1M1J B; 
#chains in the Genus database with same CATH topology
 2WNP F;  2JHM F;  1FIB A;  2OYI B;  1RE4 C;  1N73 C;  1Z3S A;  2J3O A;  1M1J C;  2J0G A;  2JHK F;  1RF1 C;  2J2P A;  1FID A;  2J3F A;  1JC9 A;  1LT9 C;  2J60 A;  1FZF C;  1RE4 B;  1N73 B;  1LTJ C;  3HUS C;  2XNX C;  1RF0 C;  1RF1 B;  2OYH C;  1Z3U A;  3H32 B;  2J3U A;  1FZC C;  1FZA B;  1LT9 B;  3GHG C;  3E1I C;  1FZF B;  4M7F A;  4EPU A;  3BVH C;  2Q9I C;  2JHH C;  3H32 C;  4R9T A;  1FZA C;  4R9J A;  2FIB A;  1LTJ B;  2HLO B;  1FZG C;  2FFD C;  3HUS B;  2J0Y A;  2XNX B;  1RF0 B;  2J1G A;  2JHL F;  2OYH B;  1FIC A;  1FZC B;  2D39 A;  2HLO C;  3GHG B;  3E1I B;  4M7H A;  1FZB C;  3BVH B;  2Q9I B;  2J5Z A;  2J61 B;  2H43 C;  4JZC A;  1FZG B;  2FFD B;  2HPC C;  4ZFG A;  2JHI F;  1N86 C;  2J3G A;  2Z4E C;  1FZB B;  1RE3 C;  1FZE C;  2HOD C;  4NYT A;  2H43 B;  2GY7 A;  2J64 A;  2HPC B;  1N86 B;  2OYI C;  1LWU B;  2J61 A;  2Z4E B;  2J3F D;  3FIB A;  4JYO X;  1RE3 B;  1FZE B;  2HOD B;  1LWU C;  2J0H A;  1FZD A;  1M1J B; 
#chains in the Genus database with same CATH homology
 2WNP F;  2JHM F;  1FIB A;  2OYI B;  1RE4 C;  1N73 C;  1Z3S A;  2J3O A;  1M1J C;  2J0G A;  2JHK F;  1RF1 C;  2J2P A;  1FID A;  2J3F A;  1JC9 A;  1LT9 C;  2J60 A;  1FZF C;  1RE4 B;  1N73 B;  1LTJ C;  3HUS C;  2XNX C;  1RF0 C;  1RF1 B;  2OYH C;  1Z3U A;  3H32 B;  2J3U A;  1FZC C;  1FZA B;  1LT9 B;  3GHG C;  3E1I C;  1FZF B;  4M7F A;  4EPU A;  3BVH C;  2Q9I C;  2JHH C;  3H32 C;  4R9T A;  1FZA C;  4R9J A;  2FIB A;  1LTJ B;  2HLO B;  1FZG C;  2FFD C;  3HUS B;  2J0Y A;  2XNX B;  1RF0 B;  2J1G A;  2JHL F;  2OYH B;  1FIC A;  1FZC B;  2D39 A;  2HLO C;  3E1I B;  4M7H A;  1FZB C;  3BVH B;  2Q9I B;  2J5Z A;  2J61 B;  2H43 C;  4JZC A;  1FZG B;  2FFD B;  2HPC C;  4ZFG A;  2JHI F;  1N86 C;  2J3G A;  2Z4E C;  1FZB B;  1RE3 C;  1FZE C;  2HOD C;  4NYT A;  2H43 B;  2GY7 A;  2J64 A;  2HPC B;  1N86 B;  2OYI C;  1LWU B;  2J61 A;  2Z4E B;  2J3F D;  3FIB A;  4JYO X;  1RE3 B;  1FZE B;  2HOD B;  1LWU C;  2J0H A;  1FZD A;  1M1J B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...