2HLOC

Crystal structure of fragment d-dimer from human fibrin complexed with gly-hydroxypro-arg-pro-amide
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Fibrin alpha chain
total genus 81
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 2006-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2hloC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2hloC02
1FICA 2JHMF 2Q9IB 4NYTA 2HODC 1FZGB 1M1JB 1LT9C 4ZFGA 2FFDC 2OYHB 1RE4C 1FZCB 2J2PA 1RE3B 1LTJC 1FIBA 3E1IB 1FZEB 4EPUA 1RF1C 2XNXC 2HODB 2HLOC 1RF0C 2J0GA 1FZFB 2J1GA 1LT9B 2J60A 4M7FA 2FFDB 1RE4B 4M7HA 2J61B 3BVHC 2J5ZA 4JYOX 1Z3UA 1LTJB 2HPCB 2JHIF 1RF1B 2XNXB 1FZAC 2OYIC 2J64A 1RF0B 3GHGC 1LWUC 2JHKF 1N73C 2J0HA 1FIDA 3H32C 3BVHB 2GY7A 2J3FA 3FIBA 1N86C 2FIBA 2Z4EC 4R9JA 1JC9A 2J3UA 1Z3SA 1FZAB 2OYIB 1LWUB 1FZGC 3HUSC 4R9TA 1N73B 2WNPF 2HLOB 3H32B 1FZDA 1N86B 2H43C 3E1IC 2Z4EB 2J3GA 1FZBC 2J0YA 2J61A 3HUSB 1FZFC 2Q9IC 4JZCA 1FZEC 2JHHC 2H43B 1M1JC 2OYHC 1FZBB 2HPCC 1FZCC 2D39A 1RE3C 2J3OA 2JHLF 2J3FD
chains in the Genus database with same CATH superfamily
1FICA 2JHMF 2Q9IB 4NYTA 2HODC 1FZGB 1M1JB 1LT9C 4ZFGA 2FFDC 2OYHB 1RE4C 1FZCB 2J2PA 1RE3B 1LTJC 1FIBA 3E1IB 1FZEB 4EPUA 1RF1C 2XNXC 2HODB 2HLOC 1RF0C 2J0GA 1FZFB 2J1GA 1LT9B 2J60A 4M7FA 2FFDB 1RE4B 4M7HA 2J61B 3BVHC 2J5ZA 4JYOX 1Z3UA 1LTJB 2HPCB 2JHIF 1RF1B 2XNXB 1FZAC 2OYIC 2J64A 1RF0B 3GHGC 1LWUC 2JHKF 1N73C 2J0HA 1FIDA 3H32C 3BVHB 2GY7A 2J3FA 3FIBA 1N86C 2FIBA 2Z4EC 4R9JA 1JC9A 2J3UA 1Z3SA 1FZAB 2OYIB 3GHGB 1LWUB 1FZGC 3HUSC 4R9TA 1N73B 2WNPF 2HLOB 3H32B 1FZDA 1N86B 2H43C 3E1IC 2Z4EB 2J3GA 1FZBC 2J0YA 2J61A 3HUSB 1FZFC 2Q9IC 4JZCA 1FZEC 2JHHC 2H43B 1M1JC 2OYHC 1FZBB 2HPCC 1FZCC 2D39A 1RE3C 2J3OA 2JHLF 2J3FD
chains in the Genus database with same CATH topology
1FICA 2JHMF 2Q9IB 4NYTA 2HODC 1FZGB 1M1JB 1LT9C 4ZFGA 2FFDC 2OYHB 1RE4C 1FZCB 2J2PA 1RE3B 1LTJC 1FIBA 3E1IB 1FZEB 4EPUA 1RF1C 2XNXC 2HODB 2HLOC 1RF0C 2J0GA 1FZFB 2J1GA 1LT9B 2J60A 4M7FA 2FFDB 1RE4B 4M7HA 2J61B 3BVHC 2J5ZA 4JYOX 1Z3UA 1LTJB 2HPCB 2JHIF 1RF1B 2XNXB 1FZAC 2OYIC 2J64A 1RF0B 3GHGC 1LWUC 2JHKF 1N73C 2J0HA 1FIDA 3H32C 3BVHB 2GY7A 2J3FA 3FIBA 1N86C 2FIBA 2Z4EC 4R9JA 1JC9A 2J3UA 1Z3SA 1FZAB 2OYIB 1LWUB 1FZGC 3HUSC 4R9TA 1N73B 2WNPF 2HLOB 3H32B 1FZDA 1N86B 2H43C 3E1IC 2Z4EB 2J3GA 1FZBC 2J0YA 2J61A 3HUSB 1FZFC 2Q9IC 4JZCA 1FZEC 2JHHC 2H43B 1M1JC 2OYHC 1FZBB 2HPCC 1FZCC 2D39A 1RE3C 2J3OA 2JHLF 2J3FD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FIC A;  2JHM F;  2Q9I B;  4NYT A;  2HOD C;  1FZG B;  1M1J B;  1LT9 C;  4ZFG A;  2FFD C;  2OYH B;  1RE4 C;  1FZC B;  2J2P A;  1RE3 B;  1LTJ C;  1FIB A;  3E1I B;  1FZE B;  4EPU A;  1RF1 C;  2XNX C;  2HOD B;  2HLO C;  1RF0 C;  2J0G A;  1FZF B;  2J1G A;  1LT9 B;  2J60 A;  4M7F A;  2FFD B;  1RE4 B;  4M7H A;  2J61 B;  3BVH C;  2J5Z A;  4JYO X;  1Z3U A;  1LTJ B;  2HPC B;  2JHI F;  1RF1 B;  2XNX B;  1FZA C;  2OYI C;  2J64 A;  1RF0 B;  3GHG C;  1LWU C;  2JHK F;  1N73 C;  2J0H A;  1FID A;  3H32 C;  3BVH B;  2GY7 A;  2J3F A;  3FIB A;  1N86 C;  2FIB A;  2Z4E C;  4R9J A;  1JC9 A;  2J3U A;  1Z3S A;  1FZA B;  2OYI B;  1LWU B;  1FZG C;  3HUS C;  4R9T A;  1N73 B;  2WNP F;  2HLO B;  3H32 B;  1FZD A;  1N86 B;  2H43 C;  3E1I C;  2Z4E B;  2J3G A;  1FZB C;  2J0Y A;  2J61 A;  3HUS B;  1FZF C;  2Q9I C;  4JZC A;  1FZE C;  2JHH C;  2H43 B;  1M1J C;  2OYH C;  1FZB B;  2HPC C;  1FZC C;  2D39 A;  1RE3 C;  2J3O A;  2JHL F;  2J3F D; 
#chains in the Genus database with same CATH topology
 1FIC A;  2JHM F;  2Q9I B;  4NYT A;  2HOD C;  1FZG B;  1M1J B;  1LT9 C;  4ZFG A;  2FFD C;  2OYH B;  1RE4 C;  1FZC B;  2J2P A;  1RE3 B;  1LTJ C;  1FIB A;  3E1I B;  1FZE B;  4EPU A;  1RF1 C;  2XNX C;  2HOD B;  2HLO C;  1RF0 C;  2J0G A;  1FZF B;  2J1G A;  1LT9 B;  2J60 A;  4M7F A;  2FFD B;  1RE4 B;  4M7H A;  2J61 B;  3BVH C;  2J5Z A;  4JYO X;  1Z3U A;  1LTJ B;  2HPC B;  2JHI F;  1RF1 B;  2XNX B;  1FZA C;  2OYI C;  2J64 A;  1RF0 B;  3GHG C;  1LWU C;  2JHK F;  1N73 C;  2J0H A;  1FID A;  3H32 C;  3BVH B;  2GY7 A;  2J3F A;  3FIB A;  1N86 C;  2FIB A;  2Z4E C;  4R9J A;  1JC9 A;  2J3U A;  1Z3S A;  1FZA B;  2OYI B;  3GHG B;  1LWU B;  1FZG C;  3HUS C;  4R9T A;  1N73 B;  2WNP F;  2HLO B;  3H32 B;  1FZD A;  1N86 B;  2H43 C;  3E1I C;  2Z4E B;  2J3G A;  1FZB C;  2J0Y A;  2J61 A;  3HUS B;  1FZF C;  2Q9I C;  4JZC A;  1FZE C;  2JHH C;  2H43 B;  1M1J C;  2OYH C;  1FZB B;  2HPC C;  1FZC C;  2D39 A;  1RE3 C;  2J3O A;  2JHL F;  2J3F D; 
#chains in the Genus database with same CATH homology
 1FIC A;  2JHM F;  2Q9I B;  4NYT A;  2HOD C;  1FZG B;  1M1J B;  1LT9 C;  4ZFG A;  2FFD C;  2OYH B;  1RE4 C;  1FZC B;  2J2P A;  1RE3 B;  1LTJ C;  1FIB A;  3E1I B;  1FZE B;  4EPU A;  1RF1 C;  2XNX C;  2HOD B;  2HLO C;  1RF0 C;  2J0G A;  1FZF B;  2J1G A;  1LT9 B;  2J60 A;  4M7F A;  2FFD B;  1RE4 B;  4M7H A;  2J61 B;  3BVH C;  2J5Z A;  4JYO X;  1Z3U A;  1LTJ B;  2HPC B;  2JHI F;  1RF1 B;  2XNX B;  1FZA C;  2OYI C;  2J64 A;  1RF0 B;  3GHG C;  1LWU C;  2JHK F;  1N73 C;  2J0H A;  1FID A;  3H32 C;  3BVH B;  2GY7 A;  2J3F A;  3FIB A;  1N86 C;  2FIB A;  2Z4E C;  4R9J A;  1JC9 A;  2J3U A;  1Z3S A;  1FZA B;  2OYI B;  1LWU B;  1FZG C;  3HUS C;  4R9T A;  1N73 B;  2WNP F;  2HLO B;  3H32 B;  1FZD A;  1N86 B;  2H43 C;  3E1I C;  2Z4E B;  2J3G A;  1FZB C;  2J0Y A;  2J61 A;  3HUS B;  1FZF C;  2Q9I C;  4JZC A;  1FZE C;  2JHH C;  2H43 B;  1M1J C;  2OYH C;  1FZB B;  2HPC C;  1FZC C;  2D39 A;  1RE3 C;  2J3O A;  2JHL F;  2J3F D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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