2HPC | Genus

Total Genus 51

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	51
sequence length	305
structure length	305
Chain Sequence	EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 305 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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305 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Blood clotting
molecule keywords	Fibrinogen alpha chain
total genus	51
structure length	305
sequence length	305
chains with identical sequence	F, I, L
ec nomenclature
pdb deposition date	2006-07-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF00147	Fibrinogen_C	Fibrinogen beta and gamma chains, C-terminal globular domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.215.10	Alpha Beta	Alpha-Beta Complex	Gamma Fibrinogen; Chain A, domain 1	Gamma Fibrinogen, chain A, domain 1	2hpcC01
4.10.530.10	Few Secondary Structures	Irregular	Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2	Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2	2hpcC02

3HUSC 2OYHB 2J61A 1N73B 1Z3UA 1N73C 4R9TA 2J61B 2Q9IC 2H43B 2J0HA 2H43C 1FZDA 1FZFB 1FZFC 1RF0B 2GY7A 1RF0C 2J1GA 1LWUB 1LWUC 4JYOX 3BVHB 1LT9B 3HUSB 3BVHC 1LT9C 3FIBA 1FZBB 2Q9IB 2J3UA 1FZBC 1JC9A 2J60A 2J3OA 2J3FD 1FIDA 2HODC 1RE4B 1RE4C 2J0GA 2Z4EB 1Z3SA 1FZCC 1LTJC 2Z4EC 2J5ZA 2J2PA 2JHHC 2WNPF 1N86B 1N86C 2OYIB 2OYIC 2FIBA 1M1JC 2JHKF 2JHLF 1FZAC 3GHGC 3H32C 4NYTA 2D39A 2XNXB 2XNXC 4JZCA 2HODB 1FZEB 2J3FA 1FZEC 1FIBA 4M7FA 1RF1C 1FZCB 1LTJB 4M7HA 2HPCB 2OYHC 2HPCC 2J3GA 1RE3B 1M1JB 4ZFGA 2JHIF 3E1IB 1RE3C 2J0YA 1FZAB 3E1IC 1FICA 3H32B 2J64A 2JHMF 1FZGB 1FZGC 2FFDB 1RF1B 2FFDC 2HLOB 2HLOC 4R9JA 4EPUA
chains in the Genus database with same CATH superfamily

3HUSC 2OYHB 2J61A 1N73B 1Z3UA 1N73C 4R9TA 2J61B 2Q9IC 2H43B 2J0HA 2H43C 1FZDA 1FZFB 1FZFC 1RF0B 2GY7A 1RF0C 2J1GA 1LWUB 1LWUC 4JYOX 3BVHB 1LT9B 3HUSB 3BVHC 1LT9C 3FIBA 1FZBB 2Q9IB 2J3UA 1FZBC 1JC9A 2J60A 2J3OA 2J3FD 1FIDA 2HODC 1RE4B 1RE4C 2J0GA 2Z4EB 1Z3SA 1FZCC 1LTJC 2Z4EC 2J5ZA 2J2PA 2JHHC 2WNPF 1N86B 1N86C 2OYIB 2OYIC 2FIBA 1M1JC 2JHKF 3GHGB 2JHLF 1FZAC 3GHGC 3H32C 4NYTA 2D39A 2XNXB 2XNXC 4JZCA 2HODB 1FZEB 2J3FA 1FZEC 1FIBA 4M7FA 1RF1C 1FZCB 1LTJB 4M7HA 2HPCB 2OYHC 2HPCC 2J3GA 1RE3B 1M1JB 4ZFGA 2JHIF 3E1IB 1RE3C 2J0YA 1FZAB 3E1IC 1FICA 3H32B 2J64A 2JHMF 1FZGB 1FZGC 2FFDB 1RF1B 2FFDC 2HLOB 2HLOC 4R9JA 4EPUA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3HUS C;  2OYH B;  2J61 A;  1N73 B;  1Z3U A;  1N73 C;  4R9T A;  2J61 B;  2Q9I C;  2H43 B;  2J0H A;  2H43 C;  1FZD A;  1FZF B;  1FZF C;  1RF0 B;  2GY7 A;  1RF0 C;  2J1G A;  1LWU B;  1LWU C;  4JYO X;  3BVH B;  1LT9 B;  3HUS B;  3BVH C;  1LT9 C;  3FIB A;  1FZB B;  2Q9I B;  2J3U A;  1FZB C;  1JC9 A;  2J60 A;  2J3O A;  2J3F D;  1FID A;  2HOD C;  1RE4 B;  1RE4 C;  2J0G A;  2Z4E B;  1Z3S A;  1FZC C;  1LTJ C;  2Z4E C;  2J5Z A;  2J2P A;  2JHH C;  2WNP F;  1N86 B;  1N86 C;  2OYI B;  2OYI C;  2FIB A;  1M1J C;  2JHK F;  2JHL F;  1FZA C;  3GHG C;  3H32 C;  4NYT A;  2D39 A;  2XNX B;  2XNX C;  4JZC A;  2HOD B;  1FZE B;  2J3F A;  1FZE C;  1FIB A;  4M7F A;  1RF1 C;  1FZC B;  1LTJ B;  4M7H A;  2HPC B;  2OYH C;  2HPC C;  2J3G A;  1RE3 B;  1M1J B;  4ZFG A;  2JHI F;  3E1I B;  1RE3 C;  2J0Y A;  1FZA B;  3E1I C;  1FIC A;  3H32 B;  2J64 A;  2JHM F;  1FZG B;  1FZG C;  2FFD B;  1RF1 B;  2FFD C;  2HLO B;  2HLO C;  4R9J A;  4EPU A; 
#chains in the Genus database with same CATH topology
 3HUS C;  2OYH B;  2J61 A;  1N73 B;  1Z3U A;  1N73 C;  4R9T A;  2J61 B;  2Q9I C;  2H43 B;  2J0H A;  2H43 C;  1FZD A;  1FZF B;  1FZF C;  1RF0 B;  2GY7 A;  1RF0 C;  2J1G A;  1LWU B;  1LWU C;  4JYO X;  3BVH B;  1LT9 B;  3HUS B;  3BVH C;  1LT9 C;  3FIB A;  1FZB B;  2Q9I B;  2J3U A;  1FZB C;  1JC9 A;  2J60 A;  2J3O A;  2J3F D;  1FID A;  2HOD C;  1RE4 B;  1RE4 C;  2J0G A;  2Z4E B;  1Z3S A;  1FZC C;  1LTJ C;  2Z4E C;  2J5Z A;  2J2P A;  2JHH C;  2WNP F;  1N86 B;  1N86 C;  2OYI B;  2OYI C;  2FIB A;  1M1J C;  2JHK F;  3GHG B;  2JHL F;  1FZA C;  3GHG C;  3H32 C;  4NYT A;  2D39 A;  2XNX B;  2XNX C;  4JZC A;  2HOD B;  1FZE B;  2J3F A;  1FZE C;  1FIB A;  4M7F A;  1RF1 C;  1FZC B;  1LTJ B;  4M7H A;  2HPC B;  2OYH C;  2HPC C;  2J3G A;  1RE3 B;  1M1J B;  4ZFG A;  2JHI F;  3E1I B;  1RE3 C;  2J0Y A;  1FZA B;  3E1I C;  1FIC A;  3H32 B;  2J64 A;  2JHM F;  1FZG B;  1FZG C;  2FFD B;  1RF1 B;  2FFD C;  2HLO B;  2HLO C;  4R9J A;  4EPU A; 
#chains in the Genus database with same CATH homology
 3HUS C;  2OYH B;  2J61 A;  1N73 B;  1Z3U A;  1N73 C;  4R9T A;  2J61 B;  2Q9I C;  2H43 B;  2J0H A;  2H43 C;  1FZD A;  1FZF B;  1FZF C;  1RF0 B;  2GY7 A;  1RF0 C;  2J1G A;  1LWU B;  1LWU C;  4JYO X;  3BVH B;  1LT9 B;  3HUS B;  3BVH C;  1LT9 C;  3FIB A;  1FZB B;  2Q9I B;  2J3U A;  1FZB C;  1JC9 A;  2J60 A;  2J3O A;  2J3F D;  1FID A;  2HOD C;  1RE4 B;  1RE4 C;  2J0G A;  2Z4E B;  1Z3S A;  1FZC C;  1LTJ C;  2Z4E C;  2J5Z A;  2J2P A;  2JHH C;  2WNP F;  1N86 B;  1N86 C;  2OYI B;  2OYI C;  2FIB A;  1M1J C;  2JHK F;  2JHL F;  1FZA C;  3GHG C;  3H32 C;  4NYT A;  2D39 A;  2XNX B;  2XNX C;  4JZC A;  2HOD B;  1FZE B;  2J3F A;  1FZE C;  1FIB A;  4M7F A;  1RF1 C;  1FZC B;  1LTJ B;  4M7H A;  2HPC B;  2OYH C;  2HPC C;  2J3G A;  1RE3 B;  1M1J B;  4ZFG A;  2JHI F;  3E1I B;  1RE3 C;  2J0Y A;  1FZA B;  3E1I C;  1FIC A;  3H32 B;  2J64 A;  2JHM F;  1FZG B;  1FZG C;  2FFD B;  1RF1 B;  2FFD C;  2HLO B;  2HLO C;  4R9J A;  4EPU A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2HPCC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations