2HPCC

Crystal structure of fragment d from human fibrinogen complexed with gly-pro-arg-pro-amide.
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
305
structure length
305
Chain Sequence
EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 51
structure length 305
sequence length 305
chains with identical sequence F, I, L
ec nomenclature
pdb deposition date 2006-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2hpcC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2hpcC02
2J0GA 2GY7A 1N73C 1N86C 3HUSC 1LWUB 4R9TA 2J64A 3BVHC 4NYTA 4EPUA 4ZFGA 2Z4EC 3H32C 1N86B 3HUSB 1FIBA 3BVHB 2Z4EB 3H32B 2FFDC 4JZCA 1RF0C 2J5ZA 1FZDA 2D39A 2HODC 2FFDB 4R9JA 2J61B 1RF0B 1FZEC 1LTJC 2H43C 1LWUC 2HODB 1JC9A 2J61A 2JHHC 2JHIF 1FZEB 1FZAC 1LTJB 2H43B 2J60A 2J2PA 2HPCB 2OYIB 2J1GA 4JYOX 1RF1C 1RE4C 1RE3B 1FZAB 2WNPF 3E1IC 1M1JC 2J3FD 2XNXC 3GHGC 2JHLF 1FZGC 2HPCC 2J3GA 2OYIC 1RF1B 1RE4B 1FZCC 2HLOC 1LT9C 3E1IB 1M1JB 1Z3UA 2Q9IC 1FIDA 4M7HA 2XNXB 1RE3C 4M7FA 2JHKF 1FZGB 2J3UA 1FZCB 2HLOB 1Z3SA 1LT9B 1FZBC 2J3OA 2Q9IB 3FIBA 2J3FA 2FIBA 2J0YA 2OYHC 1FZFC 1N73B 2JHMF 1FICA 1FZBB 2OYHB 2J0HA 1FZFB
chains in the Genus database with same CATH superfamily
2J0GA 2GY7A 1N73C 1N86C 3HUSC 1LWUB 4R9TA 2J64A 3BVHC 4NYTA 4EPUA 4ZFGA 2Z4EC 3H32C 1N86B 3HUSB 1FIBA 3BVHB 2Z4EB 3H32B 2FFDC 4JZCA 1RF0C 2J5ZA 1FZDA 2D39A 2HODC 2FFDB 4R9JA 2J61B 1RF0B 1FZEC 1LTJC 2H43C 1LWUC 2HODB 1JC9A 2J61A 2JHHC 2JHIF 1FZEB 1FZAC 1LTJB 2H43B 2J60A 2J2PA 2HPCB 2OYIB 2J1GA 4JYOX 1RF1C 1RE4C 1RE3B 1FZAB 2WNPF 3E1IC 1M1JC 2J3FD 2XNXC 3GHGC 2JHLF 1FZGC 2HPCC 2J3GA 2OYIC 1RF1B 1RE4B 1FZCC 2HLOC 1LT9C 3E1IB 1M1JB 1Z3UA 2Q9IC 1FIDA 4M7HA 2XNXB 1RE3C 3GHGB 4M7FA 2JHKF 1FZGB 2J3UA 1FZCB 2HLOB 1Z3SA 1LT9B 1FZBC 2J3OA 2Q9IB 3FIBA 2J3FA 2FIBA 2J0YA 2OYHC 1FZFC 1N73B 2JHMF 1FICA 1FZBB 2OYHB 2J0HA 1FZFB
chains in the Genus database with same CATH topology
2J0GA 2GY7A 1N73C 1N86C 3HUSC 1LWUB 4R9TA 2J64A 3BVHC 4NYTA 4EPUA 4ZFGA 2Z4EC 3H32C 1N86B 3HUSB 1FIBA 3BVHB 2Z4EB 3H32B 2FFDC 4JZCA 1RF0C 2J5ZA 1FZDA 2D39A 2HODC 2FFDB 4R9JA 2J61B 1RF0B 1FZEC 1LTJC 2H43C 1LWUC 2HODB 1JC9A 2J61A 2JHHC 2JHIF 1FZEB 1FZAC 1LTJB 2H43B 2J60A 2J2PA 2HPCB 2OYIB 2J1GA 4JYOX 1RF1C 1RE4C 1RE3B 1FZAB 2WNPF 3E1IC 1M1JC 2J3FD 2XNXC 3GHGC 2JHLF 1FZGC 2HPCC 2J3GA 2OYIC 1RF1B 1RE4B 1FZCC 2HLOC 1LT9C 3E1IB 1M1JB 1Z3UA 2Q9IC 1FIDA 4M7HA 2XNXB 1RE3C 4M7FA 2JHKF 1FZGB 2J3UA 1FZCB 2HLOB 1Z3SA 1LT9B 1FZBC 2J3OA 2Q9IB 3FIBA 2J3FA 2FIBA 2J0YA 2OYHC 1FZFC 1N73B 2JHMF 1FICA 1FZBB 2OYHB 2J0HA 1FZFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J0G A;  2GY7 A;  1N73 C;  1N86 C;  3HUS C;  1LWU B;  4R9T A;  2J64 A;  3BVH C;  4NYT A;  4EPU A;  4ZFG A;  2Z4E C;  3H32 C;  1N86 B;  3HUS B;  1FIB A;  3BVH B;  2Z4E B;  3H32 B;  2FFD C;  4JZC A;  1RF0 C;  2J5Z A;  1FZD A;  2D39 A;  2HOD C;  2FFD B;  4R9J A;  2J61 B;  1RF0 B;  1FZE C;  1LTJ C;  2H43 C;  1LWU C;  2HOD B;  1JC9 A;  2J61 A;  2JHH C;  2JHI F;  1FZE B;  1FZA C;  1LTJ B;  2H43 B;  2J60 A;  2J2P A;  2HPC B;  2OYI B;  2J1G A;  4JYO X;  1RF1 C;  1RE4 C;  1RE3 B;  1FZA B;  2WNP F;  3E1I C;  1M1J C;  2J3F D;  2XNX C;  3GHG C;  2JHL F;  1FZG C;  2HPC C;  2J3G A;  2OYI C;  1RF1 B;  1RE4 B;  1FZC C;  2HLO C;  1LT9 C;  3E1I B;  1M1J B;  1Z3U A;  2Q9I C;  1FID A;  4M7H A;  2XNX B;  1RE3 C;  4M7F A;  2JHK F;  1FZG B;  2J3U A;  1FZC B;  2HLO B;  1Z3S A;  1LT9 B;  1FZB C;  2J3O A;  2Q9I B;  3FIB A;  2J3F A;  2FIB A;  2J0Y A;  2OYH C;  1FZF C;  1N73 B;  2JHM F;  1FIC A;  1FZB B;  2OYH B;  2J0H A;  1FZF B; 
#chains in the Genus database with same CATH topology
 2J0G A;  2GY7 A;  1N73 C;  1N86 C;  3HUS C;  1LWU B;  4R9T A;  2J64 A;  3BVH C;  4NYT A;  4EPU A;  4ZFG A;  2Z4E C;  3H32 C;  1N86 B;  3HUS B;  1FIB A;  3BVH B;  2Z4E B;  3H32 B;  2FFD C;  4JZC A;  1RF0 C;  2J5Z A;  1FZD A;  2D39 A;  2HOD C;  2FFD B;  4R9J A;  2J61 B;  1RF0 B;  1FZE C;  1LTJ C;  2H43 C;  1LWU C;  2HOD B;  1JC9 A;  2J61 A;  2JHH C;  2JHI F;  1FZE B;  1FZA C;  1LTJ B;  2H43 B;  2J60 A;  2J2P A;  2HPC B;  2OYI B;  2J1G A;  4JYO X;  1RF1 C;  1RE4 C;  1RE3 B;  1FZA B;  2WNP F;  3E1I C;  1M1J C;  2J3F D;  2XNX C;  3GHG C;  2JHL F;  1FZG C;  2HPC C;  2J3G A;  2OYI C;  1RF1 B;  1RE4 B;  1FZC C;  2HLO C;  1LT9 C;  3E1I B;  1M1J B;  1Z3U A;  2Q9I C;  1FID A;  4M7H A;  2XNX B;  1RE3 C;  3GHG B;  4M7F A;  2JHK F;  1FZG B;  2J3U A;  1FZC B;  2HLO B;  1Z3S A;  1LT9 B;  1FZB C;  2J3O A;  2Q9I B;  3FIB A;  2J3F A;  2FIB A;  2J0Y A;  2OYH C;  1FZF C;  1N73 B;  2JHM F;  1FIC A;  1FZB B;  2OYH B;  2J0H A;  1FZF B; 
#chains in the Genus database with same CATH homology
 2J0G A;  2GY7 A;  1N73 C;  1N86 C;  3HUS C;  1LWU B;  4R9T A;  2J64 A;  3BVH C;  4NYT A;  4EPU A;  4ZFG A;  2Z4E C;  3H32 C;  1N86 B;  3HUS B;  1FIB A;  3BVH B;  2Z4E B;  3H32 B;  2FFD C;  4JZC A;  1RF0 C;  2J5Z A;  1FZD A;  2D39 A;  2HOD C;  2FFD B;  4R9J A;  2J61 B;  1RF0 B;  1FZE C;  1LTJ C;  2H43 C;  1LWU C;  2HOD B;  1JC9 A;  2J61 A;  2JHH C;  2JHI F;  1FZE B;  1FZA C;  1LTJ B;  2H43 B;  2J60 A;  2J2P A;  2HPC B;  2OYI B;  2J1G A;  4JYO X;  1RF1 C;  1RE4 C;  1RE3 B;  1FZA B;  2WNP F;  3E1I C;  1M1J C;  2J3F D;  2XNX C;  3GHG C;  2JHL F;  1FZG C;  2HPC C;  2J3G A;  2OYI C;  1RF1 B;  1RE4 B;  1FZC C;  2HLO C;  1LT9 C;  3E1I B;  1M1J B;  1Z3U A;  2Q9I C;  1FID A;  4M7H A;  2XNX B;  1RE3 C;  4M7F A;  2JHK F;  1FZG B;  2J3U A;  1FZC B;  2HLO B;  1Z3S A;  1LT9 B;  1FZB C;  2J3O A;  2Q9I B;  3FIB A;  2J3F A;  2FIB A;  2J0Y A;  2OYH C;  1FZF C;  1N73 B;  2JHM F;  1FIC A;  1FZB B;  2OYH B;  2J0H A;  1FZF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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