2HPCC

Crystal structure of fragment d from human fibrinogen complexed with gly-pro-arg-pro-amide.
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
305
structure length
305
Chain Sequence
EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 51
structure length 305
sequence length 305
chains with identical sequence F, I, L
ec nomenclature
pdb deposition date 2006-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2hpcC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2hpcC02
1FZBB 3FIBA 3GHGC 2HODC 3H32C 1FZEC 2J3UA 2WNPF 2H43B 2Q9IB 1LT9B 1JC9A 1M1JB 2FFDB 1FZFC 1FZAC 2OYIB 2J3GA 2J3OA 1N86C 1N73B 1LTJB 1FIDA 3BVHB 1RE4C 4JYOX 2FIBA 2JHIF 2J3FD 3E1IC 4R9JA 2HODB 3H32B 1FZEB 2Z4EC 2HLOC 2JHHC 2GY7A 2HPCC 2J5ZA 1FZAB 1FZFB 2OYHC 1RF1C 1N86B 1Z3SA 1RE4B 2J0GA 1FICA 2J64A 2XNXC 3E1IB 4EPUA 3HUSC 2JHLF 1LWUC 2J1GA 2J0HA 2JHKF 1Z3UA 1FZCC 2Z4EB 1RE3C 2OYIC 2J60A 2HLOB 1RF0C 2HPCB 1LTJC 4ZFGA 2OYHB 1RF1B 2J61B 2XNXB 4R9TA 3HUSB 1FZGC 1LWUB 4JZCA 1FZBC 2H43C 2Q9IC 1LT9C 1M1JC 2JHMF 1FZCB 2FFDC 1FIBA 1RE3B 2J0YA 4M7HA 1RF0B 1N73C 2J2PA 3BVHC 2J61A 4M7FA 4NYTA 2J3FA 2D39A 1FZDA 1FZGB
chains in the Genus database with same CATH superfamily
1FZBB 3FIBA 3GHGC 2HODC 3H32C 1FZEC 2J3UA 2WNPF 2H43B 2Q9IB 1LT9B 1JC9A 1M1JB 2FFDB 1FZFC 1FZAC 2OYIB 2J3GA 2J3OA 1N86C 1N73B 1LTJB 1FIDA 3BVHB 1RE4C 4JYOX 2FIBA 2JHIF 2J3FD 3E1IC 4R9JA 3GHGB 2HODB 3H32B 1FZEB 2Z4EC 2HLOC 2JHHC 2GY7A 2HPCC 2J5ZA 1FZAB 1FZFB 2OYHC 1RF1C 1N86B 1Z3SA 1RE4B 2J0GA 1FICA 2J64A 2XNXC 3E1IB 4EPUA 3HUSC 2JHLF 1LWUC 2J1GA 2J0HA 2JHKF 1Z3UA 1FZCC 2Z4EB 1RE3C 2OYIC 2J60A 2HLOB 1RF0C 2HPCB 1LTJC 4ZFGA 2OYHB 1RF1B 2J61B 2XNXB 4R9TA 3HUSB 1FZGC 1LWUB 4JZCA 1FZBC 2H43C 2Q9IC 1LT9C 1M1JC 2JHMF 1FZCB 2FFDC 1FIBA 1RE3B 2J0YA 4M7HA 1RF0B 1N73C 2J2PA 3BVHC 2J61A 4M7FA 4NYTA 2J3FA 2D39A 1FZDA 1FZGB
chains in the Genus database with same CATH topology
1FZBB 3FIBA 3GHGC 2HODC 3H32C 1FZEC 2J3UA 2WNPF 2H43B 2Q9IB 1LT9B 1JC9A 1M1JB 2FFDB 1FZFC 1FZAC 2OYIB 2J3GA 2J3OA 1N86C 1N73B 1LTJB 1FIDA 3BVHB 1RE4C 4JYOX 2FIBA 2JHIF 2J3FD 3E1IC 4R9JA 2HODB 3H32B 1FZEB 2Z4EC 2HLOC 2JHHC 2GY7A 2HPCC 2J5ZA 1FZAB 1FZFB 2OYHC 1RF1C 1N86B 1Z3SA 1RE4B 2J0GA 1FICA 2J64A 2XNXC 3E1IB 4EPUA 3HUSC 2JHLF 1LWUC 2J1GA 2J0HA 2JHKF 1Z3UA 1FZCC 2Z4EB 1RE3C 2OYIC 2J60A 2HLOB 1RF0C 2HPCB 1LTJC 4ZFGA 2OYHB 1RF1B 2J61B 2XNXB 4R9TA 3HUSB 1FZGC 1LWUB 4JZCA 1FZBC 2H43C 2Q9IC 1LT9C 1M1JC 2JHMF 1FZCB 2FFDC 1FIBA 1RE3B 2J0YA 4M7HA 1RF0B 1N73C 2J2PA 3BVHC 2J61A 4M7FA 4NYTA 2J3FA 2D39A 1FZDA 1FZGB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZB B;  3FIB A;  3GHG C;  2HOD C;  3H32 C;  1FZE C;  2J3U A;  2WNP F;  2H43 B;  2Q9I B;  1LT9 B;  1JC9 A;  1M1J B;  2FFD B;  1FZF C;  1FZA C;  2OYI B;  2J3G A;  2J3O A;  1N86 C;  1N73 B;  1LTJ B;  1FID A;  3BVH B;  1RE4 C;  4JYO X;  2FIB A;  2JHI F;  2J3F D;  3E1I C;  4R9J A;  2HOD B;  3H32 B;  1FZE B;  2Z4E C;  2HLO C;  2JHH C;  2GY7 A;  2HPC C;  2J5Z A;  1FZA B;  1FZF B;  2OYH C;  1RF1 C;  1N86 B;  1Z3S A;  1RE4 B;  2J0G A;  1FIC A;  2J64 A;  2XNX C;  3E1I B;  4EPU A;  3HUS C;  2JHL F;  1LWU C;  2J1G A;  2J0H A;  2JHK F;  1Z3U A;  1FZC C;  2Z4E B;  1RE3 C;  2OYI C;  2J60 A;  2HLO B;  1RF0 C;  2HPC B;  1LTJ C;  4ZFG A;  2OYH B;  1RF1 B;  2J61 B;  2XNX B;  4R9T A;  3HUS B;  1FZG C;  1LWU B;  4JZC A;  1FZB C;  2H43 C;  2Q9I C;  1LT9 C;  1M1J C;  2JHM F;  1FZC B;  2FFD C;  1FIB A;  1RE3 B;  2J0Y A;  4M7H A;  1RF0 B;  1N73 C;  2J2P A;  3BVH C;  2J61 A;  4M7F A;  4NYT A;  2J3F A;  2D39 A;  1FZD A;  1FZG B; 
#chains in the Genus database with same CATH topology
 1FZB B;  3FIB A;  3GHG C;  2HOD C;  3H32 C;  1FZE C;  2J3U A;  2WNP F;  2H43 B;  2Q9I B;  1LT9 B;  1JC9 A;  1M1J B;  2FFD B;  1FZF C;  1FZA C;  2OYI B;  2J3G A;  2J3O A;  1N86 C;  1N73 B;  1LTJ B;  1FID A;  3BVH B;  1RE4 C;  4JYO X;  2FIB A;  2JHI F;  2J3F D;  3E1I C;  4R9J A;  3GHG B;  2HOD B;  3H32 B;  1FZE B;  2Z4E C;  2HLO C;  2JHH C;  2GY7 A;  2HPC C;  2J5Z A;  1FZA B;  1FZF B;  2OYH C;  1RF1 C;  1N86 B;  1Z3S A;  1RE4 B;  2J0G A;  1FIC A;  2J64 A;  2XNX C;  3E1I B;  4EPU A;  3HUS C;  2JHL F;  1LWU C;  2J1G A;  2J0H A;  2JHK F;  1Z3U A;  1FZC C;  2Z4E B;  1RE3 C;  2OYI C;  2J60 A;  2HLO B;  1RF0 C;  2HPC B;  1LTJ C;  4ZFG A;  2OYH B;  1RF1 B;  2J61 B;  2XNX B;  4R9T A;  3HUS B;  1FZG C;  1LWU B;  4JZC A;  1FZB C;  2H43 C;  2Q9I C;  1LT9 C;  1M1J C;  2JHM F;  1FZC B;  2FFD C;  1FIB A;  1RE3 B;  2J0Y A;  4M7H A;  1RF0 B;  1N73 C;  2J2P A;  3BVH C;  2J61 A;  4M7F A;  4NYT A;  2J3F A;  2D39 A;  1FZD A;  1FZG B; 
#chains in the Genus database with same CATH homology
 1FZB B;  3FIB A;  3GHG C;  2HOD C;  3H32 C;  1FZE C;  2J3U A;  2WNP F;  2H43 B;  2Q9I B;  1LT9 B;  1JC9 A;  1M1J B;  2FFD B;  1FZF C;  1FZA C;  2OYI B;  2J3G A;  2J3O A;  1N86 C;  1N73 B;  1LTJ B;  1FID A;  3BVH B;  1RE4 C;  4JYO X;  2FIB A;  2JHI F;  2J3F D;  3E1I C;  4R9J A;  2HOD B;  3H32 B;  1FZE B;  2Z4E C;  2HLO C;  2JHH C;  2GY7 A;  2HPC C;  2J5Z A;  1FZA B;  1FZF B;  2OYH C;  1RF1 C;  1N86 B;  1Z3S A;  1RE4 B;  2J0G A;  1FIC A;  2J64 A;  2XNX C;  3E1I B;  4EPU A;  3HUS C;  2JHL F;  1LWU C;  2J1G A;  2J0H A;  2JHK F;  1Z3U A;  1FZC C;  2Z4E B;  1RE3 C;  2OYI C;  2J60 A;  2HLO B;  1RF0 C;  2HPC B;  1LTJ C;  4ZFG A;  2OYH B;  1RF1 B;  2J61 B;  2XNX B;  4R9T A;  3HUS B;  1FZG C;  1LWU B;  4JZC A;  1FZB C;  2H43 C;  2Q9I C;  1LT9 C;  1M1J C;  2JHM F;  1FZC B;  2FFD C;  1FIB A;  1RE3 B;  2J0Y A;  4M7H A;  1RF0 B;  1N73 C;  2J2P A;  3BVH C;  2J61 A;  4M7F A;  4NYT A;  2J3F A;  2D39 A;  1FZD A;  1FZG B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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