2JHHC

Structure of globular heads of m-ficolin at acidic ph
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
217
structure length
208
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 59
structure length 208
sequence length 217
chains with identical sequence F
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhhC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhhC02
4R9TA 2H43C 1FZGC 2OYIC 2JHMF 3BVHC 3H32C 1FZBB 1FIDA 1RF0B 2HODB 4M7FA 1RE4C 2J0YA 1FIBA 1FZCC 2J60A 1FZGB 2H43B 2OYIB 2J64A 1N73C 2HLOC 1Z3SA 3BVHB 2WNPF 3H32B 3E1IC 1RE4B 1FZEC 1LTJC 2J3GA 1FZCB 1FZDA 2JHHC 1N73B 2HLOB 1RE3C 1N86C 2FFDC 4NYTA 2Z4EC 3E1IB 4R9JA 2Q9IC 1FZEB 1LTJB 3GHGC 3FIBA 4ZFGA 2OYHC 2J61A 1RE3B 1RF1C 1N86B 2FFDB 2J2PA 2J3UA 2Z4EB 1FICA 2GY7A 2Q9IB 2FIBA 1LWUC 2JHKF 3HUSC 2HPCC 1Z3UA 2JHLF 2J0GA 2OYHB 2XNXC 1RF1B 2J1GA 2J3FD 2JHIF 1M1JC 2J3OA 1LWUB 3HUSB 4M7HA 4JZCA 2HPCB 2J0HA 1FZFC 2J5ZA 1FZAC 2XNXB 4JYOX 1LT9C 1M1JB 4EPUA 2J61B 1FZFB 1FZBC 1FZAB 2D39A 1LT9B 1RF0C 2HODC 2J3FA 1JC9A
chains in the Genus database with same CATH superfamily
4R9TA 2H43C 1FZGC 2OYIC 2JHMF 3BVHC 3H32C 1FZBB 1FIDA 1RF0B 2HODB 4M7FA 1RE4C 2J0YA 1FIBA 1FZCC 2J60A 1FZGB 2H43B 2OYIB 2J64A 1N73C 2HLOC 1Z3SA 3BVHB 2WNPF 3H32B 3E1IC 1RE4B 1FZEC 1LTJC 2J3GA 1FZCB 1FZDA 3GHGB 2JHHC 1N73B 2HLOB 1RE3C 1N86C 2FFDC 4NYTA 2Z4EC 3E1IB 4R9JA 2Q9IC 1FZEB 1LTJB 3GHGC 3FIBA 4ZFGA 2OYHC 2J61A 1RE3B 1RF1C 1N86B 2FFDB 2J2PA 2J3UA 2Z4EB 1FICA 2GY7A 2Q9IB 2FIBA 1LWUC 2JHKF 3HUSC 2HPCC 1Z3UA 2JHLF 2J0GA 2OYHB 2XNXC 1RF1B 2J1GA 2J3FD 2JHIF 1M1JC 2J3OA 1LWUB 3HUSB 4M7HA 4JZCA 2HPCB 2J0HA 1FZFC 2J5ZA 1FZAC 2XNXB 4JYOX 1LT9C 1M1JB 4EPUA 2J61B 1FZFB 1FZBC 1FZAB 2D39A 1LT9B 1RF0C 2HODC 2J3FA 1JC9A
chains in the Genus database with same CATH topology
4R9TA 2H43C 1FZGC 2OYIC 2JHMF 3BVHC 3H32C 1FZBB 1FIDA 1RF0B 2HODB 4M7FA 1RE4C 2J0YA 1FIBA 1FZCC 2J60A 1FZGB 2H43B 2OYIB 2J64A 1N73C 2HLOC 1Z3SA 3BVHB 2WNPF 3H32B 3E1IC 1RE4B 1FZEC 1LTJC 2J3GA 1FZCB 1FZDA 2JHHC 1N73B 2HLOB 1RE3C 1N86C 2FFDC 4NYTA 2Z4EC 3E1IB 4R9JA 2Q9IC 1FZEB 1LTJB 3GHGC 3FIBA 4ZFGA 2OYHC 2J61A 1RE3B 1RF1C 1N86B 2FFDB 2J2PA 2J3UA 2Z4EB 1FICA 2GY7A 2Q9IB 2FIBA 1LWUC 2JHKF 3HUSC 2HPCC 1Z3UA 2JHLF 2J0GA 2OYHB 2XNXC 1RF1B 2J1GA 2J3FD 2JHIF 1M1JC 2J3OA 1LWUB 3HUSB 4M7HA 4JZCA 2HPCB 2J0HA 1FZFC 2J5ZA 1FZAC 2XNXB 4JYOX 1LT9C 1M1JB 4EPUA 2J61B 1FZFB 1FZBC 1FZAB 2D39A 1LT9B 1RF0C 2HODC 2J3FA 1JC9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R9T A;  2H43 C;  1FZG C;  2OYI C;  2JHM F;  3BVH C;  3H32 C;  1FZB B;  1FID A;  1RF0 B;  2HOD B;  4M7F A;  1RE4 C;  2J0Y A;  1FIB A;  1FZC C;  2J60 A;  1FZG B;  2H43 B;  2OYI B;  2J64 A;  1N73 C;  2HLO C;  1Z3S A;  3BVH B;  2WNP F;  3H32 B;  3E1I C;  1RE4 B;  1FZE C;  1LTJ C;  2J3G A;  1FZC B;  1FZD A;  2JHH C;  1N73 B;  2HLO B;  1RE3 C;  1N86 C;  2FFD C;  4NYT A;  2Z4E C;  3E1I B;  4R9J A;  2Q9I C;  1FZE B;  1LTJ B;  3GHG C;  3FIB A;  4ZFG A;  2OYH C;  2J61 A;  1RE3 B;  1RF1 C;  1N86 B;  2FFD B;  2J2P A;  2J3U A;  2Z4E B;  1FIC A;  2GY7 A;  2Q9I B;  2FIB A;  1LWU C;  2JHK F;  3HUS C;  2HPC C;  1Z3U A;  2JHL F;  2J0G A;  2OYH B;  2XNX C;  1RF1 B;  2J1G A;  2J3F D;  2JHI F;  1M1J C;  2J3O A;  1LWU B;  3HUS B;  4M7H A;  4JZC A;  2HPC B;  2J0H A;  1FZF C;  2J5Z A;  1FZA C;  2XNX B;  4JYO X;  1LT9 C;  1M1J B;  4EPU A;  2J61 B;  1FZF B;  1FZB C;  1FZA B;  2D39 A;  1LT9 B;  1RF0 C;  2HOD C;  2J3F A;  1JC9 A; 
#chains in the Genus database with same CATH topology
 4R9T A;  2H43 C;  1FZG C;  2OYI C;  2JHM F;  3BVH C;  3H32 C;  1FZB B;  1FID A;  1RF0 B;  2HOD B;  4M7F A;  1RE4 C;  2J0Y A;  1FIB A;  1FZC C;  2J60 A;  1FZG B;  2H43 B;  2OYI B;  2J64 A;  1N73 C;  2HLO C;  1Z3S A;  3BVH B;  2WNP F;  3H32 B;  3E1I C;  1RE4 B;  1FZE C;  1LTJ C;  2J3G A;  1FZC B;  1FZD A;  3GHG B;  2JHH C;  1N73 B;  2HLO B;  1RE3 C;  1N86 C;  2FFD C;  4NYT A;  2Z4E C;  3E1I B;  4R9J A;  2Q9I C;  1FZE B;  1LTJ B;  3GHG C;  3FIB A;  4ZFG A;  2OYH C;  2J61 A;  1RE3 B;  1RF1 C;  1N86 B;  2FFD B;  2J2P A;  2J3U A;  2Z4E B;  1FIC A;  2GY7 A;  2Q9I B;  2FIB A;  1LWU C;  2JHK F;  3HUS C;  2HPC C;  1Z3U A;  2JHL F;  2J0G A;  2OYH B;  2XNX C;  1RF1 B;  2J1G A;  2J3F D;  2JHI F;  1M1J C;  2J3O A;  1LWU B;  3HUS B;  4M7H A;  4JZC A;  2HPC B;  2J0H A;  1FZF C;  2J5Z A;  1FZA C;  2XNX B;  4JYO X;  1LT9 C;  1M1J B;  4EPU A;  2J61 B;  1FZF B;  1FZB C;  1FZA B;  2D39 A;  1LT9 B;  1RF0 C;  2HOD C;  2J3F A;  1JC9 A; 
#chains in the Genus database with same CATH homology
 4R9T A;  2H43 C;  1FZG C;  2OYI C;  2JHM F;  3BVH C;  3H32 C;  1FZB B;  1FID A;  1RF0 B;  2HOD B;  4M7F A;  1RE4 C;  2J0Y A;  1FIB A;  1FZC C;  2J60 A;  1FZG B;  2H43 B;  2OYI B;  2J64 A;  1N73 C;  2HLO C;  1Z3S A;  3BVH B;  2WNP F;  3H32 B;  3E1I C;  1RE4 B;  1FZE C;  1LTJ C;  2J3G A;  1FZC B;  1FZD A;  2JHH C;  1N73 B;  2HLO B;  1RE3 C;  1N86 C;  2FFD C;  4NYT A;  2Z4E C;  3E1I B;  4R9J A;  2Q9I C;  1FZE B;  1LTJ B;  3GHG C;  3FIB A;  4ZFG A;  2OYH C;  2J61 A;  1RE3 B;  1RF1 C;  1N86 B;  2FFD B;  2J2P A;  2J3U A;  2Z4E B;  1FIC A;  2GY7 A;  2Q9I B;  2FIB A;  1LWU C;  2JHK F;  3HUS C;  2HPC C;  1Z3U A;  2JHL F;  2J0G A;  2OYH B;  2XNX C;  1RF1 B;  2J1G A;  2J3F D;  2JHI F;  1M1J C;  2J3O A;  1LWU B;  3HUS B;  4M7H A;  4JZC A;  2HPC B;  2J0H A;  1FZF C;  2J5Z A;  1FZA C;  2XNX B;  4JYO X;  1LT9 C;  1M1J B;  4EPU A;  2J61 B;  1FZF B;  1FZB C;  1FZA B;  2D39 A;  1LT9 B;  1RF0 C;  2HOD C;  2J3F A;  1JC9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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