2JHIF

Structure of globular heads of m-ficolin complexed with n-acetyl-d- galactosamine
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 75
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhiF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhiF02
2OYHC 2FFDB 1LWUB 1RE4B 3E1IB 1RE3C 2J3UA 1FZAC 2J0HA 2JHLF 1N86B 2Z4EB 2J3FA 3H32C 2J1GA 2JHIF 1FZGC 4NYTA 1FZCC 1RF0C 2JHKF 4R9JA 2FIBA 2HODC 4ZFGA 3GHGC 1RF1C 1M1JB 1FZBB 2J0YA 2FFDC 1FZEB 2Q9IB 3HUSB 1RE4C 3E1IC 2GY7A 2OYIC 1LTJB 1N86C 2Z4EC 2JHHC 1FZFB 2XNXB 2OYHB 1FIBA 2J61A 2J64A 1Z3UA 1FICA 1N73B 1M1JC 2HLOB 1JC9A 1FZBC 1LWUC 1FZEC 1LT9B 4M7FA 2Q9IC 3HUSC 2D39A 4EPUA 2WNPF 4JZCA 3BVHB 1Z3SA 1LTJC 2HPCB 2H43B 1FZFC 2XNXC 2J5ZA 2J3FD 2J61B 2J0GA 2J3GA 1RE3B 1N73C 2HLOC 1FZAB 3FIBA 2OYIB 1FIDA 2JHMF 4JYOX 2J60A 2J3OA 3H32B 4R9TA 1LT9C 1FZGB 1FZCB 1RF0B 4M7HA 2HODB 3BVHC 2J2PA 2HPCC 1RF1B 1FZDA 2H43C
chains in the Genus database with same CATH superfamily
2OYHC 2FFDB 1LWUB 1RE4B 3E1IB 1RE3C 2J3UA 1FZAC 2J0HA 2JHLF 1N86B 2Z4EB 2J3FA 3H32C 2J1GA 2JHIF 1FZGC 4NYTA 1FZCC 1RF0C 2JHKF 4R9JA 2FIBA 2HODC 4ZFGA 3GHGC 1RF1C 1M1JB 1FZBB 2J0YA 2FFDC 1FZEB 2Q9IB 3HUSB 1RE4C 3E1IC 2GY7A 2OYIC 1LTJB 1N86C 2Z4EC 2JHHC 1FZFB 2XNXB 2OYHB 1FIBA 2J61A 2J64A 1Z3UA 1FICA 1N73B 1M1JC 2HLOB 1JC9A 1FZBC 1LWUC 1FZEC 1LT9B 4M7FA 2Q9IC 3HUSC 2D39A 4EPUA 2WNPF 4JZCA 3BVHB 1Z3SA 1LTJC 2HPCB 2H43B 1FZFC 2XNXC 2J5ZA 2J3FD 2J61B 2J0GA 2J3GA 1RE3B 1N73C 2HLOC 1FZAB 3FIBA 2OYIB 1FIDA 2JHMF 4JYOX 2J60A 2J3OA 3H32B 4R9TA 1LT9C 1FZGB 1FZCB 1RF0B 4M7HA 2HODB 3GHGB 3BVHC 2J2PA 2HPCC 1RF1B 1FZDA 2H43C
chains in the Genus database with same CATH topology
2OYHC 2FFDB 1LWUB 1RE4B 3E1IB 1RE3C 2J3UA 1FZAC 2J0HA 2JHLF 1N86B 2Z4EB 2J3FA 3H32C 2J1GA 2JHIF 1FZGC 4NYTA 1FZCC 1RF0C 2JHKF 4R9JA 2FIBA 2HODC 4ZFGA 3GHGC 1RF1C 1M1JB 1FZBB 2J0YA 2FFDC 1FZEB 2Q9IB 3HUSB 1RE4C 3E1IC 2GY7A 2OYIC 1LTJB 1N86C 2Z4EC 2JHHC 1FZFB 2XNXB 2OYHB 1FIBA 2J61A 2J64A 1Z3UA 1FICA 1N73B 1M1JC 2HLOB 1JC9A 1FZBC 1LWUC 1FZEC 1LT9B 4M7FA 2Q9IC 3HUSC 2D39A 4EPUA 2WNPF 4JZCA 3BVHB 1Z3SA 1LTJC 2HPCB 2H43B 1FZFC 2XNXC 2J5ZA 2J3FD 2J61B 2J0GA 2J3GA 1RE3B 1N73C 2HLOC 1FZAB 3FIBA 2OYIB 1FIDA 2JHMF 4JYOX 2J60A 2J3OA 3H32B 4R9TA 1LT9C 1FZGB 1FZCB 1RF0B 4M7HA 2HODB 3BVHC 2J2PA 2HPCC 1RF1B 1FZDA 2H43C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OYH C;  2FFD B;  1LWU B;  1RE4 B;  3E1I B;  1RE3 C;  2J3U A;  1FZA C;  2J0H A;  2JHL F;  1N86 B;  2Z4E B;  2J3F A;  3H32 C;  2J1G A;  2JHI F;  1FZG C;  4NYT A;  1FZC C;  1RF0 C;  2JHK F;  4R9J A;  2FIB A;  2HOD C;  4ZFG A;  3GHG C;  1RF1 C;  1M1J B;  1FZB B;  2J0Y A;  2FFD C;  1FZE B;  2Q9I B;  3HUS B;  1RE4 C;  3E1I C;  2GY7 A;  2OYI C;  1LTJ B;  1N86 C;  2Z4E C;  2JHH C;  1FZF B;  2XNX B;  2OYH B;  1FIB A;  2J61 A;  2J64 A;  1Z3U A;  1FIC A;  1N73 B;  1M1J C;  2HLO B;  1JC9 A;  1FZB C;  1LWU C;  1FZE C;  1LT9 B;  4M7F A;  2Q9I C;  3HUS C;  2D39 A;  4EPU A;  2WNP F;  4JZC A;  3BVH B;  1Z3S A;  1LTJ C;  2HPC B;  2H43 B;  1FZF C;  2XNX C;  2J5Z A;  2J3F D;  2J61 B;  2J0G A;  2J3G A;  1RE3 B;  1N73 C;  2HLO C;  1FZA B;  3FIB A;  2OYI B;  1FID A;  2JHM F;  4JYO X;  2J60 A;  2J3O A;  3H32 B;  4R9T A;  1LT9 C;  1FZG B;  1FZC B;  1RF0 B;  4M7H A;  2HOD B;  3BVH C;  2J2P A;  2HPC C;  1RF1 B;  1FZD A;  2H43 C; 
#chains in the Genus database with same CATH topology
 2OYH C;  2FFD B;  1LWU B;  1RE4 B;  3E1I B;  1RE3 C;  2J3U A;  1FZA C;  2J0H A;  2JHL F;  1N86 B;  2Z4E B;  2J3F A;  3H32 C;  2J1G A;  2JHI F;  1FZG C;  4NYT A;  1FZC C;  1RF0 C;  2JHK F;  4R9J A;  2FIB A;  2HOD C;  4ZFG A;  3GHG C;  1RF1 C;  1M1J B;  1FZB B;  2J0Y A;  2FFD C;  1FZE B;  2Q9I B;  3HUS B;  1RE4 C;  3E1I C;  2GY7 A;  2OYI C;  1LTJ B;  1N86 C;  2Z4E C;  2JHH C;  1FZF B;  2XNX B;  2OYH B;  1FIB A;  2J61 A;  2J64 A;  1Z3U A;  1FIC A;  1N73 B;  1M1J C;  2HLO B;  1JC9 A;  1FZB C;  1LWU C;  1FZE C;  1LT9 B;  4M7F A;  2Q9I C;  3HUS C;  2D39 A;  4EPU A;  2WNP F;  4JZC A;  3BVH B;  1Z3S A;  1LTJ C;  2HPC B;  2H43 B;  1FZF C;  2XNX C;  2J5Z A;  2J3F D;  2J61 B;  2J0G A;  2J3G A;  1RE3 B;  1N73 C;  2HLO C;  1FZA B;  3FIB A;  2OYI B;  1FID A;  2JHM F;  4JYO X;  2J60 A;  2J3O A;  3H32 B;  4R9T A;  1LT9 C;  1FZG B;  1FZC B;  1RF0 B;  4M7H A;  2HOD B;  3GHG B;  3BVH C;  2J2P A;  2HPC C;  1RF1 B;  1FZD A;  2H43 C; 
#chains in the Genus database with same CATH homology
 2OYH C;  2FFD B;  1LWU B;  1RE4 B;  3E1I B;  1RE3 C;  2J3U A;  1FZA C;  2J0H A;  2JHL F;  1N86 B;  2Z4E B;  2J3F A;  3H32 C;  2J1G A;  2JHI F;  1FZG C;  4NYT A;  1FZC C;  1RF0 C;  2JHK F;  4R9J A;  2FIB A;  2HOD C;  4ZFG A;  3GHG C;  1RF1 C;  1M1J B;  1FZB B;  2J0Y A;  2FFD C;  1FZE B;  2Q9I B;  3HUS B;  1RE4 C;  3E1I C;  2GY7 A;  2OYI C;  1LTJ B;  1N86 C;  2Z4E C;  2JHH C;  1FZF B;  2XNX B;  2OYH B;  1FIB A;  2J61 A;  2J64 A;  1Z3U A;  1FIC A;  1N73 B;  1M1J C;  2HLO B;  1JC9 A;  1FZB C;  1LWU C;  1FZE C;  1LT9 B;  4M7F A;  2Q9I C;  3HUS C;  2D39 A;  4EPU A;  2WNP F;  4JZC A;  3BVH B;  1Z3S A;  1LTJ C;  2HPC B;  2H43 B;  1FZF C;  2XNX C;  2J5Z A;  2J3F D;  2J61 B;  2J0G A;  2J3G A;  1RE3 B;  1N73 C;  2HLO C;  1FZA B;  3FIB A;  2OYI B;  1FID A;  2JHM F;  4JYO X;  2J60 A;  2J3O A;  3H32 B;  4R9T A;  1LT9 C;  1FZG B;  1FZC B;  1RF0 B;  4M7H A;  2HOD B;  3BVH C;  2J2P A;  2HPC C;  1RF1 B;  1FZD A;  2H43 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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