2JHKF

Structure of globular heads of m-ficolin complexed with n-acetyl-d- glucosamine
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 76
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhkF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhkF02
4M7FA 2JHIF 1FZAB 2J3FA 2JHKF 2WNPF 2OYHC 1RE3B 4JZCA 1N73C 1JC9A 1Z3UA 2J2PA 1FIDA 3E1IB 1FIBA 3HUSB 1Z3SA 1LTJB 2HPCC 2FFDC 1FZBC 2Z4EC 2J61B 1RF1B 1FZGB 2JHHC 1LT9C 2H43C 2HODB 1RF0C 1M1JC 1RE4B 1FZFC 2J60A 2XNXB 1FZCC 2HLOC 1FZEB 4R9JA 1FZAC 3H32B 2J1GA 2J3GA 2Q9IB 2J5ZA 1N86B 2D39A 1RE3C 4EPUA 2OYIB 3BVHB 2JHLF 2FIBA 2J0HA 2J61A 3E1IC 3HUSC 2J0YA 1LTJC 1LWUB 1FZDA 3FIBA 2J64A 1RF1C 1FZGC 3GHGC 2OYHB 2HODC 1RE4C 4M7HA 1N73B 4ZFGA 2XNXC 4R9TA 4NYTA 1FZEC 2HPCB 2FFDB 1FZBB 3H32C 1FICA 2Z4EB 1LT9B 2Q9IC 2JHMF 1N86C 2H43B 1RF0B 2J3FD 1M1JB 1FZFB 2J3UA 3BVHC 2OYIC 2GY7A 1FZCB 2J0GA 2J3OA 4JYOX 2HLOB 1LWUC
chains in the Genus database with same CATH superfamily
4M7FA 2JHIF 1FZAB 2J3FA 2JHKF 2WNPF 2OYHC 1RE3B 4JZCA 1N73C 1JC9A 1Z3UA 2J2PA 1FIDA 3E1IB 1FIBA 3HUSB 1Z3SA 1LTJB 2HPCC 2FFDC 1FZBC 2Z4EC 2J61B 1RF1B 1FZGB 2JHHC 1LT9C 3GHGB 2H43C 2HODB 1RF0C 1M1JC 1RE4B 1FZFC 2J60A 2XNXB 1FZCC 2HLOC 1FZEB 4R9JA 1FZAC 3H32B 2J1GA 2J3GA 2Q9IB 2J5ZA 1N86B 2D39A 1RE3C 4EPUA 2OYIB 3BVHB 2JHLF 2FIBA 2J0HA 2J61A 3E1IC 3HUSC 2J0YA 1LTJC 1LWUB 1FZDA 3FIBA 2J64A 1RF1C 1FZGC 3GHGC 2OYHB 2HODC 1RE4C 4M7HA 1N73B 4ZFGA 2XNXC 4R9TA 4NYTA 1FZEC 2HPCB 2FFDB 1FZBB 3H32C 1FICA 2Z4EB 1LT9B 2Q9IC 2JHMF 1N86C 2H43B 1RF0B 2J3FD 1M1JB 1FZFB 2J3UA 3BVHC 2OYIC 2GY7A 1FZCB 2J0GA 2J3OA 4JYOX 2HLOB 1LWUC
chains in the Genus database with same CATH topology
4M7FA 2JHIF 1FZAB 2J3FA 2JHKF 2WNPF 2OYHC 1RE3B 4JZCA 1N73C 1JC9A 1Z3UA 2J2PA 1FIDA 3E1IB 1FIBA 3HUSB 1Z3SA 1LTJB 2HPCC 2FFDC 1FZBC 2Z4EC 2J61B 1RF1B 1FZGB 2JHHC 1LT9C 2H43C 2HODB 1RF0C 1M1JC 1RE4B 1FZFC 2J60A 2XNXB 1FZCC 2HLOC 1FZEB 4R9JA 1FZAC 3H32B 2J1GA 2J3GA 2Q9IB 2J5ZA 1N86B 2D39A 1RE3C 4EPUA 2OYIB 3BVHB 2JHLF 2FIBA 2J0HA 2J61A 3E1IC 3HUSC 2J0YA 1LTJC 1LWUB 1FZDA 3FIBA 2J64A 1RF1C 1FZGC 3GHGC 2OYHB 2HODC 1RE4C 4M7HA 1N73B 4ZFGA 2XNXC 4R9TA 4NYTA 1FZEC 2HPCB 2FFDB 1FZBB 3H32C 1FICA 2Z4EB 1LT9B 2Q9IC 2JHMF 1N86C 2H43B 1RF0B 2J3FD 1M1JB 1FZFB 2J3UA 3BVHC 2OYIC 2GY7A 1FZCB 2J0GA 2J3OA 4JYOX 2HLOB 1LWUC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4M7F A;  2JHI F;  1FZA B;  2J3F A;  2JHK F;  2WNP F;  2OYH C;  1RE3 B;  4JZC A;  1N73 C;  1JC9 A;  1Z3U A;  2J2P A;  1FID A;  3E1I B;  1FIB A;  3HUS B;  1Z3S A;  1LTJ B;  2HPC C;  2FFD C;  1FZB C;  2Z4E C;  2J61 B;  1RF1 B;  1FZG B;  2JHH C;  1LT9 C;  2H43 C;  2HOD B;  1RF0 C;  1M1J C;  1RE4 B;  1FZF C;  2J60 A;  2XNX B;  1FZC C;  2HLO C;  1FZE B;  4R9J A;  1FZA C;  3H32 B;  2J1G A;  2J3G A;  2Q9I B;  2J5Z A;  1N86 B;  2D39 A;  1RE3 C;  4EPU A;  2OYI B;  3BVH B;  2JHL F;  2FIB A;  2J0H A;  2J61 A;  3E1I C;  3HUS C;  2J0Y A;  1LTJ C;  1LWU B;  1FZD A;  3FIB A;  2J64 A;  1RF1 C;  1FZG C;  3GHG C;  2OYH B;  2HOD C;  1RE4 C;  4M7H A;  1N73 B;  4ZFG A;  2XNX C;  4R9T A;  4NYT A;  1FZE C;  2HPC B;  2FFD B;  1FZB B;  3H32 C;  1FIC A;  2Z4E B;  1LT9 B;  2Q9I C;  2JHM F;  1N86 C;  2H43 B;  1RF0 B;  2J3F D;  1M1J B;  1FZF B;  2J3U A;  3BVH C;  2OYI C;  2GY7 A;  1FZC B;  2J0G A;  2J3O A;  4JYO X;  2HLO B;  1LWU C; 
#chains in the Genus database with same CATH topology
 4M7F A;  2JHI F;  1FZA B;  2J3F A;  2JHK F;  2WNP F;  2OYH C;  1RE3 B;  4JZC A;  1N73 C;  1JC9 A;  1Z3U A;  2J2P A;  1FID A;  3E1I B;  1FIB A;  3HUS B;  1Z3S A;  1LTJ B;  2HPC C;  2FFD C;  1FZB C;  2Z4E C;  2J61 B;  1RF1 B;  1FZG B;  2JHH C;  1LT9 C;  3GHG B;  2H43 C;  2HOD B;  1RF0 C;  1M1J C;  1RE4 B;  1FZF C;  2J60 A;  2XNX B;  1FZC C;  2HLO C;  1FZE B;  4R9J A;  1FZA C;  3H32 B;  2J1G A;  2J3G A;  2Q9I B;  2J5Z A;  1N86 B;  2D39 A;  1RE3 C;  4EPU A;  2OYI B;  3BVH B;  2JHL F;  2FIB A;  2J0H A;  2J61 A;  3E1I C;  3HUS C;  2J0Y A;  1LTJ C;  1LWU B;  1FZD A;  3FIB A;  2J64 A;  1RF1 C;  1FZG C;  3GHG C;  2OYH B;  2HOD C;  1RE4 C;  4M7H A;  1N73 B;  4ZFG A;  2XNX C;  4R9T A;  4NYT A;  1FZE C;  2HPC B;  2FFD B;  1FZB B;  3H32 C;  1FIC A;  2Z4E B;  1LT9 B;  2Q9I C;  2JHM F;  1N86 C;  2H43 B;  1RF0 B;  2J3F D;  1M1J B;  1FZF B;  2J3U A;  3BVH C;  2OYI C;  2GY7 A;  1FZC B;  2J0G A;  2J3O A;  4JYO X;  2HLO B;  1LWU C; 
#chains in the Genus database with same CATH homology
 4M7F A;  2JHI F;  1FZA B;  2J3F A;  2JHK F;  2WNP F;  2OYH C;  1RE3 B;  4JZC A;  1N73 C;  1JC9 A;  1Z3U A;  2J2P A;  1FID A;  3E1I B;  1FIB A;  3HUS B;  1Z3S A;  1LTJ B;  2HPC C;  2FFD C;  1FZB C;  2Z4E C;  2J61 B;  1RF1 B;  1FZG B;  2JHH C;  1LT9 C;  2H43 C;  2HOD B;  1RF0 C;  1M1J C;  1RE4 B;  1FZF C;  2J60 A;  2XNX B;  1FZC C;  2HLO C;  1FZE B;  4R9J A;  1FZA C;  3H32 B;  2J1G A;  2J3G A;  2Q9I B;  2J5Z A;  1N86 B;  2D39 A;  1RE3 C;  4EPU A;  2OYI B;  3BVH B;  2JHL F;  2FIB A;  2J0H A;  2J61 A;  3E1I C;  3HUS C;  2J0Y A;  1LTJ C;  1LWU B;  1FZD A;  3FIB A;  2J64 A;  1RF1 C;  1FZG C;  3GHG C;  2OYH B;  2HOD C;  1RE4 C;  4M7H A;  1N73 B;  4ZFG A;  2XNX C;  4R9T A;  4NYT A;  1FZE C;  2HPC B;  2FFD B;  1FZB B;  3H32 C;  1FIC A;  2Z4E B;  1LT9 B;  2Q9I C;  2JHM F;  1N86 C;  2H43 B;  1RF0 B;  2J3F D;  1M1J B;  1FZF B;  2J3U A;  3BVH C;  2OYI C;  2GY7 A;  1FZC B;  2J0G A;  2J3O A;  4JYO X;  2HLO B;  1LWU C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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