2JHKF

Structure of globular heads of m-ficolin complexed with n-acetyl-d- glucosamine
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 76
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhkF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhkF02
1RF0C 1RE4B 1N86C 1RF1B 2J1GA 2J3FD 1RE4C 1LTJB 2JHHC 1FICA 2WNPF 2Q9IB 1FZDA 1LTJC 2Z4EB 2OYHB 4JYOX 2Z4EC 2OYHC 1Z3SA 2GY7A 2J60A 1FZGC 1FZEB 1LT9B 4EPUA 2J3FA 1FZEC 3HUSB 1LT9C 1FZAB 3HUSC 2D39A 3GHGC 1FZAC 2J3OA 3H32B 1RE3B 2FFDB 4JZCA 4M7HA 2J0HA 1FZBB 2J61A 3E1IB 1LWUC 2J64A 2J3GA 3H32C 1RE3C 2FFDC 1FZGB 1FZCB 1JC9A 1FZBC 1M1JC 3E1IC 2OYIC 2J2PA 1FZCC 2HODB 2XNXB 4R9JA 2HODC 2XNXC 2J5ZA 2H43C 2FIBA 1LWUB 2HPCB 1M1JB 2HLOC 4NYTA 2J3UA 2OYIB 2HPCC 1FIBA 2J0YA 1FZFB 1FZFC 1Z3UA 2H43B 1RF1C 2JHKF 1N73B 1FIDA 2JHMF 4R9TA 2JHIF 2Q9IC 3BVHB 2JHLF 2HLOB 3FIBA 4ZFGA 4M7FA 2J0GA 1N73C 3BVHC 1RF0B 2J61B 1N86B
chains in the Genus database with same CATH superfamily
1RF0C 1RE4B 1N86C 1RF1B 2J1GA 2J3FD 1RE4C 1LTJB 2JHHC 1FICA 2WNPF 2Q9IB 1FZDA 1LTJC 2Z4EB 2OYHB 4JYOX 2Z4EC 2OYHC 1Z3SA 2GY7A 2J60A 1FZGC 1FZEB 1LT9B 4EPUA 2J3FA 1FZEC 3HUSB 3GHGB 1LT9C 1FZAB 3HUSC 2D39A 3GHGC 1FZAC 2J3OA 3H32B 1RE3B 2FFDB 4JZCA 4M7HA 2J0HA 1FZBB 2J61A 3E1IB 1LWUC 2J64A 2J3GA 3H32C 1RE3C 2FFDC 1FZGB 1FZCB 1JC9A 1FZBC 1M1JC 3E1IC 2OYIC 2J2PA 1FZCC 2HODB 2XNXB 4R9JA 2HODC 2XNXC 2J5ZA 2H43C 2FIBA 1LWUB 2HPCB 1M1JB 2HLOC 4NYTA 2J3UA 2OYIB 1FIBA 2HPCC 2J0YA 1FZFB 1FZFC 1Z3UA 2H43B 1RF1C 2JHKF 1N73B 1FIDA 2JHMF 4R9TA 2JHIF 2Q9IC 3BVHB 2JHLF 2HLOB 3FIBA 4ZFGA 4M7FA 2J0GA 1N73C 3BVHC 1RF0B 2J61B 1N86B
chains in the Genus database with same CATH topology
1RF0C 1RE4B 1N86C 1RF1B 2J1GA 2J3FD 1RE4C 1LTJB 2JHHC 1FICA 2WNPF 2Q9IB 1FZDA 1LTJC 2Z4EB 2OYHB 4JYOX 2Z4EC 2OYHC 1Z3SA 2GY7A 2J60A 1FZGC 1FZEB 1LT9B 4EPUA 2J3FA 1FZEC 3HUSB 1LT9C 1FZAB 3HUSC 2D39A 3GHGC 1FZAC 2J3OA 3H32B 1RE3B 2FFDB 4JZCA 4M7HA 2J0HA 1FZBB 2J61A 3E1IB 1LWUC 2J64A 2J3GA 3H32C 1RE3C 2FFDC 1FZGB 1FZCB 1JC9A 1FZBC 1M1JC 3E1IC 2OYIC 2J2PA 1FZCC 2HODB 2XNXB 4R9JA 2HODC 2XNXC 2J5ZA 2H43C 2FIBA 1LWUB 2HPCB 1M1JB 2HLOC 4NYTA 2J3UA 2OYIB 2HPCC 1FIBA 2J0YA 1FZFB 1FZFC 1Z3UA 2H43B 1RF1C 2JHKF 1N73B 1FIDA 2JHMF 4R9TA 2JHIF 2Q9IC 3BVHB 2JHLF 2HLOB 3FIBA 4ZFGA 4M7FA 2J0GA 1N73C 3BVHC 1RF0B 2J61B 1N86B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF0 C;  1RE4 B;  1N86 C;  1RF1 B;  2J1G A;  2J3F D;  1RE4 C;  1LTJ B;  2JHH C;  1FIC A;  2WNP F;  2Q9I B;  1FZD A;  1LTJ C;  2Z4E B;  2OYH B;  4JYO X;  2Z4E C;  2OYH C;  1Z3S A;  2GY7 A;  2J60 A;  1FZG C;  1FZE B;  1LT9 B;  4EPU A;  2J3F A;  1FZE C;  3HUS B;  1LT9 C;  1FZA B;  3HUS C;  2D39 A;  3GHG C;  1FZA C;  2J3O A;  3H32 B;  1RE3 B;  2FFD B;  4JZC A;  4M7H A;  2J0H A;  1FZB B;  2J61 A;  3E1I B;  1LWU C;  2J64 A;  2J3G A;  3H32 C;  1RE3 C;  2FFD C;  1FZG B;  1FZC B;  1JC9 A;  1FZB C;  1M1J C;  3E1I C;  2OYI C;  2J2P A;  1FZC C;  2HOD B;  2XNX B;  4R9J A;  2HOD C;  2XNX C;  2J5Z A;  2H43 C;  2FIB A;  1LWU B;  2HPC B;  1M1J B;  2HLO C;  4NYT A;  2J3U A;  2OYI B;  2HPC C;  1FIB A;  2J0Y A;  1FZF B;  1FZF C;  1Z3U A;  2H43 B;  1RF1 C;  2JHK F;  1N73 B;  1FID A;  2JHM F;  4R9T A;  2JHI F;  2Q9I C;  3BVH B;  2JHL F;  2HLO B;  3FIB A;  4ZFG A;  4M7F A;  2J0G A;  1N73 C;  3BVH C;  1RF0 B;  2J61 B;  1N86 B; 
#chains in the Genus database with same CATH topology
 1RF0 C;  1RE4 B;  1N86 C;  1RF1 B;  2J1G A;  2J3F D;  1RE4 C;  1LTJ B;  2JHH C;  1FIC A;  2WNP F;  2Q9I B;  1FZD A;  1LTJ C;  2Z4E B;  2OYH B;  4JYO X;  2Z4E C;  2OYH C;  1Z3S A;  2GY7 A;  2J60 A;  1FZG C;  1FZE B;  1LT9 B;  4EPU A;  2J3F A;  1FZE C;  3HUS B;  3GHG B;  1LT9 C;  1FZA B;  3HUS C;  2D39 A;  3GHG C;  1FZA C;  2J3O A;  3H32 B;  1RE3 B;  2FFD B;  4JZC A;  4M7H A;  2J0H A;  1FZB B;  2J61 A;  3E1I B;  1LWU C;  2J64 A;  2J3G A;  3H32 C;  1RE3 C;  2FFD C;  1FZG B;  1FZC B;  1JC9 A;  1FZB C;  1M1J C;  3E1I C;  2OYI C;  2J2P A;  1FZC C;  2HOD B;  2XNX B;  4R9J A;  2HOD C;  2XNX C;  2J5Z A;  2H43 C;  2FIB A;  1LWU B;  2HPC B;  1M1J B;  2HLO C;  4NYT A;  2J3U A;  2OYI B;  1FIB A;  2HPC C;  2J0Y A;  1FZF B;  1FZF C;  1Z3U A;  2H43 B;  1RF1 C;  2JHK F;  1N73 B;  1FID A;  2JHM F;  4R9T A;  2JHI F;  2Q9I C;  3BVH B;  2JHL F;  2HLO B;  3FIB A;  4ZFG A;  4M7F A;  2J0G A;  1N73 C;  3BVH C;  1RF0 B;  2J61 B;  1N86 B; 
#chains in the Genus database with same CATH homology
 1RF0 C;  1RE4 B;  1N86 C;  1RF1 B;  2J1G A;  2J3F D;  1RE4 C;  1LTJ B;  2JHH C;  1FIC A;  2WNP F;  2Q9I B;  1FZD A;  1LTJ C;  2Z4E B;  2OYH B;  4JYO X;  2Z4E C;  2OYH C;  1Z3S A;  2GY7 A;  2J60 A;  1FZG C;  1FZE B;  1LT9 B;  4EPU A;  2J3F A;  1FZE C;  3HUS B;  1LT9 C;  1FZA B;  3HUS C;  2D39 A;  3GHG C;  1FZA C;  2J3O A;  3H32 B;  1RE3 B;  2FFD B;  4JZC A;  4M7H A;  2J0H A;  1FZB B;  2J61 A;  3E1I B;  1LWU C;  2J64 A;  2J3G A;  3H32 C;  1RE3 C;  2FFD C;  1FZG B;  1FZC B;  1JC9 A;  1FZB C;  1M1J C;  3E1I C;  2OYI C;  2J2P A;  1FZC C;  2HOD B;  2XNX B;  4R9J A;  2HOD C;  2XNX C;  2J5Z A;  2H43 C;  2FIB A;  1LWU B;  2HPC B;  1M1J B;  2HLO C;  4NYT A;  2J3U A;  2OYI B;  2HPC C;  1FIB A;  2J0Y A;  1FZF B;  1FZF C;  1Z3U A;  2H43 B;  1RF1 C;  2JHK F;  1N73 B;  1FID A;  2JHM F;  4R9T A;  2JHI F;  2Q9I C;  3BVH B;  2JHL F;  2HLO B;  3FIB A;  4ZFG A;  4M7F A;  2J0G A;  1N73 C;  3BVH C;  1RF0 B;  2J61 B;  1N86 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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