2JHLF

Structure of globular heads of m-ficolin complexed with sialic acid
Total Genus 75

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTI3 (107-110)TI1 (81-84)TI2 (82-85)TIV2 (120-123)O4 (82-110)S2 (112-118)AH1 (89-95)TIV5 (217-220)TI6 (213-216)O5 (89-117)S1 (101-106)S9 (210-212)S8 (205-207)O1 (139-141)TI'1 (121-124)TIV1 (118-121)AH2 (143-148)TI4 (152-155)S3 (126-132)TIV3 (132-135)AH3 (161-169)S5 (157-158)S6 (173-180)TIV4 (201-204)TI5 (181-184)S7 (186-196)S4 (150-151)3H1 (199-201)Updating...
connected with : NaN
molecule tags Sugar binding protein
source organism Homo sapiens
publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule keywords FICOLIN-1
total genus 75
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhlF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhlF02
2JHIF 2JHKF 1RE4B 1RF0B 4NYTA 3HUSB 1FZEC 2XNXB 1LTJB 1Z3UA 2OYIB 1N73C 1LT9B 1RF1C 3E1IB 1FZAC 2Q9IC 3GHGC 1N86C 2J3GA 1FZBC 3H32C 1LWUB 2H43C 2FFDC 1FZCB 1FICA 2J61B 2J61A 2J0HA 2JHMF 2HODC 2FIBA 2J0GA 2HLOC 2HPCC 1FZDA 4JZCA 1M1JB 4ZFGA 2J60A 2OYHB 1FIDA 1RE4C 1RF0C 1FZFB 1FIBA 2J64A 1Z3SA 3HUSC 1RE3B 2J3OA 2XNXC 2J3FD 2J2PA 1LTJC 3BVHB 2OYIC 1LT9C 3E1IC 2J3UA 1FZGB 2Z4EB 1LWUC 4EPUA 2JHHC 1FZCC 4M7FA 3FIBA 2Z4EC 2GY7A 1JC9A 1FZEB 2J0YA 4R9TA 1M1JC 2OYHC 2D39A 2JHLF 2WNPF 1N73B 2J1GA 1FZFC 1RF1B 1FZAB 2Q9IB 2J5ZA 4R9JA 1N86B 1RE3C 1FZBB 3H32B 3BVHC 2H43B 2FFDB 4M7HA 2J3FA 1FZGC 2HODB 4JYOX 2HLOB 2HPCB
chains in the Genus database with same CATH superfamily
2JHIF 2JHKF 1RE4B 1RF0B 4NYTA 3HUSB 1FZEC 2XNXB 1LTJB 1Z3UA 2OYIB 1N73C 1LT9B 1RF1C 3E1IB 1FZAC 2Q9IC 3GHGC 1N86C 2J3GA 1FZBC 3H32C 1LWUB 2H43C 2FFDC 1FZCB 1FICA 2J61B 2J61A 2J0HA 2JHMF 2HODC 2FIBA 2J0GA 2HLOC 2HPCC 1FZDA 4JZCA 1M1JB 4ZFGA 2J60A 2OYHB 1FIDA 1RE4C 1RF0C 1FZFB 1FIBA 2J64A 1Z3SA 3HUSC 1RE3B 2J3OA 2XNXC 2J3FD 2J2PA 1LTJC 3BVHB 2OYIC 1LT9C 3E1IC 2J3UA 1FZGB 2Z4EB 1LWUC 4EPUA 2JHHC 1FZCC 4M7FA 3FIBA 2Z4EC 2GY7A 1JC9A 1FZEB 2J0YA 4R9TA 1M1JC 2OYHC 2D39A 2JHLF 2WNPF 1N73B 2J1GA 1FZFC 1RF1B 1FZAB 2Q9IB 3GHGB 2J5ZA 4R9JA 1N86B 1RE3C 1FZBB 3H32B 3BVHC 2H43B 2FFDB 4M7HA 2J3FA 1FZGC 2HODB 4JYOX 2HLOB 2HPCB
chains in the Genus database with same CATH topology
2JHIF 2JHKF 1RE4B 1RF0B 4NYTA 3HUSB 1FZEC 2XNXB 1LTJB 1Z3UA 2OYIB 1N73C 1LT9B 1RF1C 3E1IB 1FZAC 2Q9IC 3GHGC 1N86C 2J3GA 1FZBC 3H32C 1LWUB 2H43C 2FFDC 1FZCB 1FICA 2J61B 2J61A 2J0HA 2JHMF 2HODC 2FIBA 2J0GA 2HLOC 2HPCC 1FZDA 4JZCA 1M1JB 4ZFGA 2J60A 2OYHB 1FIDA 1RE4C 1RF0C 1FZFB 1FIBA 2J64A 1Z3SA 3HUSC 1RE3B 2J3OA 2XNXC 2J3FD 2J2PA 1LTJC 3BVHB 2OYIC 1LT9C 3E1IC 2J3UA 1FZGB 2Z4EB 1LWUC 4EPUA 2JHHC 1FZCC 4M7FA 3FIBA 2Z4EC 2GY7A 1JC9A 1FZEB 2J0YA 4R9TA 1M1JC 2OYHC 2D39A 2JHLF 2WNPF 1N73B 2J1GA 1FZFC 1RF1B 1FZAB 2Q9IB 2J5ZA 4R9JA 1N86B 1RE3C 1FZBB 3H32B 3BVHC 2H43B 2FFDB 4M7HA 2J3FA 1FZGC 2HODB 4JYOX 2HLOB 2HPCB
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2JHI F;  2JHK F;  1RE4 B;  1RF0 B;  4NYT A;  3HUS B;  1FZE C;  2XNX B;  1LTJ B;  1Z3U A;  2OYI B;  1N73 C;  1LT9 B;  1RF1 C;  3E1I B;  1FZA C;  2Q9I C;  3GHG C;  1N86 C;  2J3G A;  1FZB C;  3H32 C;  1LWU B;  2H43 C;  2FFD C;  1FZC B;  1FIC A;  2J61 B;  2J61 A;  2J0H A;  2JHM F;  2HOD C;  2FIB A;  2J0G A;  2HLO C;  2HPC C;  1FZD A;  4JZC A;  1M1J B;  4ZFG A;  2J60 A;  2OYH B;  1FID A;  1RE4 C;  1RF0 C;  1FZF B;  1FIB A;  2J64 A;  1Z3S A;  3HUS C;  1RE3 B;  2J3O A;  2XNX C;  2J3F D;  2J2P A;  1LTJ C;  3BVH B;  2OYI C;  1LT9 C;  3E1I C;  2J3U A;  1FZG B;  2Z4E B;  1LWU C;  4EPU A;  2JHH C;  1FZC C;  4M7F A;  3FIB A;  2Z4E C;  2GY7 A;  1JC9 A;  1FZE B;  2J0Y A;  4R9T A;  1M1J C;  2OYH C;  2D39 A;  2JHL F;  2WNP F;  1N73 B;  2J1G A;  1FZF C;  1RF1 B;  1FZA B;  2Q9I B;  2J5Z A;  4R9J A;  1N86 B;  1RE3 C;  1FZB B;  3H32 B;  3BVH C;  2H43 B;  2FFD B;  4M7H A;  2J3F A;  1FZG C;  2HOD B;  4JYO X;  2HLO B;  2HPC B; 
#chains in the Genus database with same CATH topology
 2JHI F;  2JHK F;  1RE4 B;  1RF0 B;  4NYT A;  3HUS B;  1FZE C;  2XNX B;  1LTJ B;  1Z3U A;  2OYI B;  1N73 C;  1LT9 B;  1RF1 C;  3E1I B;  1FZA C;  2Q9I C;  3GHG C;  1N86 C;  2J3G A;  1FZB C;  3H32 C;  1LWU B;  2H43 C;  2FFD C;  1FZC B;  1FIC A;  2J61 B;  2J61 A;  2J0H A;  2JHM F;  2HOD C;  2FIB A;  2J0G A;  2HLO C;  2HPC C;  1FZD A;  4JZC A;  1M1J B;  4ZFG A;  2J60 A;  2OYH B;  1FID A;  1RE4 C;  1RF0 C;  1FZF B;  1FIB A;  2J64 A;  1Z3S A;  3HUS C;  1RE3 B;  2J3O A;  2XNX C;  2J3F D;  2J2P A;  1LTJ C;  3BVH B;  2OYI C;  1LT9 C;  3E1I C;  2J3U A;  1FZG B;  2Z4E B;  1LWU C;  4EPU A;  2JHH C;  1FZC C;  4M7F A;  3FIB A;  2Z4E C;  2GY7 A;  1JC9 A;  1FZE B;  2J0Y A;  4R9T A;  1M1J C;  2OYH C;  2D39 A;  2JHL F;  2WNP F;  1N73 B;  2J1G A;  1FZF C;  1RF1 B;  1FZA B;  2Q9I B;  3GHG B;  2J5Z A;  4R9J A;  1N86 B;  1RE3 C;  1FZB B;  3H32 B;  3BVH C;  2H43 B;  2FFD B;  4M7H A;  2J3F A;  1FZG C;  2HOD B;  4JYO X;  2HLO B;  2HPC B; 
#chains in the Genus database with same CATH homology
 2JHI F;  2JHK F;  1RE4 B;  1RF0 B;  4NYT A;  3HUS B;  1FZE C;  2XNX B;  1LTJ B;  1Z3U A;  2OYI B;  1N73 C;  1LT9 B;  1RF1 C;  3E1I B;  1FZA C;  2Q9I C;  3GHG C;  1N86 C;  2J3G A;  1FZB C;  3H32 C;  1LWU B;  2H43 C;  2FFD C;  1FZC B;  1FIC A;  2J61 B;  2J61 A;  2J0H A;  2JHM F;  2HOD C;  2FIB A;  2J0G A;  2HLO C;  2HPC C;  1FZD A;  4JZC A;  1M1J B;  4ZFG A;  2J60 A;  2OYH B;  1FID A;  1RE4 C;  1RF0 C;  1FZF B;  1FIB A;  2J64 A;  1Z3S A;  3HUS C;  1RE3 B;  2J3O A;  2XNX C;  2J3F D;  2J2P A;  1LTJ C;  3BVH B;  2OYI C;  1LT9 C;  3E1I C;  2J3U A;  1FZG B;  2Z4E B;  1LWU C;  4EPU A;  2JHH C;  1FZC C;  4M7F A;  3FIB A;  2Z4E C;  2GY7 A;  1JC9 A;  1FZE B;  2J0Y A;  4R9T A;  1M1J C;  2OYH C;  2D39 A;  2JHL F;  2WNP F;  1N73 B;  2J1G A;  1FZF C;  1RF1 B;  1FZA B;  2Q9I B;  2J5Z A;  4R9J A;  1N86 B;  1RE3 C;  1FZB B;  3H32 B;  3BVH C;  2H43 B;  2FFD B;  4M7H A;  2J3F A;  1FZG C;  2HOD B;  4JYO X;  2HLO B;  2HPC B;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite
Application loaded.