2JHLF

Structure of globular heads of m-ficolin complexed with sialic acid
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 75
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhlF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhlF02
3E1IB 1M1JB 1FZAC 1N73B 2D39A 1RF0C 4M7FA 1RF1B 1FZCC 2J2PA 3H32C 1FZBC 1FIBA 2FFDC 4NYTA 1LWUB 2OYIC 1RE3B 2Q9IB 2JHHC 3BVHB 2HPCC 4JZCA 2XNXC 2JHLF 1FZBB 1FZEB 2OYHC 2HODB 1LT9C 2J1GA 2J3FD 4M7HA 1FZFC 3FIBA 1FICA 2J3UA 2WNPF 2JHIF 1FZGB 2J64A 2OYHB 1LT9B 2J3FA 1FZAB 1RE4C 1N86C 4EPUA 2J3GA 4R9TA 1RF0B 1LTJC 1FIDA 1FZDA 1FZCB 3H32B 3HUSC 4JYOX 1RE4B 2J3OA 2FFDB 1Z3UA 2J60A 2OYIB 2HLOC 3E1IC 2GY7A 2HPCB 1M1JC 2XNXB 4ZFGA 2J0HA 1FZFB 1RF1C 2J61B 2J61A 2J0GA 2FIBA 1N86B 4R9JA 2H43C 1LWUC 1Z3SA 2Z4EC 1LTJB 3GHGC 1RE3C 2Q9IC 1JC9A 3BVHC 2JHKF 3HUSB 1FZEC 2HODC 2J0YA 2JHMF 1N73C 2H43B 2Z4EB 2HLOB 1FZGC 2J5ZA
chains in the Genus database with same CATH superfamily
3E1IB 1M1JB 1FZAC 1N73B 2D39A 1RF0C 4M7FA 1RF1B 1FZCC 2J2PA 3H32C 1FZBC 1FIBA 2FFDC 4NYTA 1LWUB 2OYIC 3GHGB 1RE3B 2Q9IB 2JHHC 3BVHB 2HPCC 4JZCA 2XNXC 2JHLF 1FZBB 1FZEB 2OYHC 2HODB 1LT9C 2J1GA 2J3FD 4M7HA 1FZFC 3FIBA 1FICA 2J3UA 2WNPF 2JHIF 1FZGB 2J64A 2OYHB 1LT9B 2J3FA 1FZAB 1RE4C 1N86C 4EPUA 2J3GA 4R9TA 1RF0B 1LTJC 1FIDA 1FZDA 1FZCB 3H32B 3HUSC 4JYOX 1RE4B 2J3OA 2FFDB 1Z3UA 2J60A 2OYIB 2HLOC 3E1IC 2GY7A 2HPCB 1M1JC 2XNXB 4ZFGA 2J0HA 1FZFB 1RF1C 2J61B 2J61A 2J0GA 2FIBA 1N86B 4R9JA 2H43C 1LWUC 1Z3SA 2Z4EC 1LTJB 3GHGC 1RE3C 2Q9IC 1JC9A 3BVHC 2JHKF 3HUSB 1FZEC 2HODC 2J0YA 2JHMF 1N73C 2H43B 2Z4EB 2HLOB 1FZGC 2J5ZA
chains in the Genus database with same CATH topology
3E1IB 1M1JB 1FZAC 1N73B 2D39A 1RF0C 4M7FA 1RF1B 1FZCC 2J2PA 3H32C 1FZBC 1FIBA 2FFDC 4NYTA 1LWUB 2OYIC 1RE3B 2Q9IB 2JHHC 3BVHB 2HPCC 4JZCA 2XNXC 2JHLF 1FZBB 1FZEB 2OYHC 2HODB 1LT9C 2J1GA 2J3FD 4M7HA 1FZFC 3FIBA 1FICA 2J3UA 2WNPF 2JHIF 1FZGB 2J64A 2OYHB 1LT9B 2J3FA 1FZAB 1RE4C 1N86C 4EPUA 2J3GA 4R9TA 1RF0B 1LTJC 1FIDA 1FZDA 1FZCB 3H32B 3HUSC 4JYOX 1RE4B 2J3OA 2FFDB 1Z3UA 2J60A 2OYIB 2HLOC 3E1IC 2GY7A 2HPCB 1M1JC 2XNXB 4ZFGA 2J0HA 1FZFB 1RF1C 2J61B 2J61A 2J0GA 2FIBA 1N86B 4R9JA 2H43C 1LWUC 1Z3SA 2Z4EC 1LTJB 3GHGC 1RE3C 2Q9IC 1JC9A 3BVHC 2JHKF 3HUSB 1FZEC 2HODC 2J0YA 2JHMF 1N73C 2H43B 2Z4EB 2HLOB 1FZGC 2J5ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E1I B;  1M1J B;  1FZA C;  1N73 B;  2D39 A;  1RF0 C;  4M7F A;  1RF1 B;  1FZC C;  2J2P A;  3H32 C;  1FZB C;  1FIB A;  2FFD C;  4NYT A;  1LWU B;  2OYI C;  1RE3 B;  2Q9I B;  2JHH C;  3BVH B;  2HPC C;  4JZC A;  2XNX C;  2JHL F;  1FZB B;  1FZE B;  2OYH C;  2HOD B;  1LT9 C;  2J1G A;  2J3F D;  4M7H A;  1FZF C;  3FIB A;  1FIC A;  2J3U A;  2WNP F;  2JHI F;  1FZG B;  2J64 A;  2OYH B;  1LT9 B;  2J3F A;  1FZA B;  1RE4 C;  1N86 C;  4EPU A;  2J3G A;  4R9T A;  1RF0 B;  1LTJ C;  1FID A;  1FZD A;  1FZC B;  3H32 B;  3HUS C;  4JYO X;  1RE4 B;  2J3O A;  2FFD B;  1Z3U A;  2J60 A;  2OYI B;  2HLO C;  3E1I C;  2GY7 A;  2HPC B;  1M1J C;  2XNX B;  4ZFG A;  2J0H A;  1FZF B;  1RF1 C;  2J61 B;  2J61 A;  2J0G A;  2FIB A;  1N86 B;  4R9J A;  2H43 C;  1LWU C;  1Z3S A;  2Z4E C;  1LTJ B;  3GHG C;  1RE3 C;  2Q9I C;  1JC9 A;  3BVH C;  2JHK F;  3HUS B;  1FZE C;  2HOD C;  2J0Y A;  2JHM F;  1N73 C;  2H43 B;  2Z4E B;  2HLO B;  1FZG C;  2J5Z A; 
#chains in the Genus database with same CATH topology
 3E1I B;  1M1J B;  1FZA C;  1N73 B;  2D39 A;  1RF0 C;  4M7F A;  1RF1 B;  1FZC C;  2J2P A;  3H32 C;  1FZB C;  1FIB A;  2FFD C;  4NYT A;  1LWU B;  2OYI C;  3GHG B;  1RE3 B;  2Q9I B;  2JHH C;  3BVH B;  2HPC C;  4JZC A;  2XNX C;  2JHL F;  1FZB B;  1FZE B;  2OYH C;  2HOD B;  1LT9 C;  2J1G A;  2J3F D;  4M7H A;  1FZF C;  3FIB A;  1FIC A;  2J3U A;  2WNP F;  2JHI F;  1FZG B;  2J64 A;  2OYH B;  1LT9 B;  2J3F A;  1FZA B;  1RE4 C;  1N86 C;  4EPU A;  2J3G A;  4R9T A;  1RF0 B;  1LTJ C;  1FID A;  1FZD A;  1FZC B;  3H32 B;  3HUS C;  4JYO X;  1RE4 B;  2J3O A;  2FFD B;  1Z3U A;  2J60 A;  2OYI B;  2HLO C;  3E1I C;  2GY7 A;  2HPC B;  1M1J C;  2XNX B;  4ZFG A;  2J0H A;  1FZF B;  1RF1 C;  2J61 B;  2J61 A;  2J0G A;  2FIB A;  1N86 B;  4R9J A;  2H43 C;  1LWU C;  1Z3S A;  2Z4E C;  1LTJ B;  3GHG C;  1RE3 C;  2Q9I C;  1JC9 A;  3BVH C;  2JHK F;  3HUS B;  1FZE C;  2HOD C;  2J0Y A;  2JHM F;  1N73 C;  2H43 B;  2Z4E B;  2HLO B;  1FZG C;  2J5Z A; 
#chains in the Genus database with same CATH homology
 3E1I B;  1M1J B;  1FZA C;  1N73 B;  2D39 A;  1RF0 C;  4M7F A;  1RF1 B;  1FZC C;  2J2P A;  3H32 C;  1FZB C;  1FIB A;  2FFD C;  4NYT A;  1LWU B;  2OYI C;  1RE3 B;  2Q9I B;  2JHH C;  3BVH B;  2HPC C;  4JZC A;  2XNX C;  2JHL F;  1FZB B;  1FZE B;  2OYH C;  2HOD B;  1LT9 C;  2J1G A;  2J3F D;  4M7H A;  1FZF C;  3FIB A;  1FIC A;  2J3U A;  2WNP F;  2JHI F;  1FZG B;  2J64 A;  2OYH B;  1LT9 B;  2J3F A;  1FZA B;  1RE4 C;  1N86 C;  4EPU A;  2J3G A;  4R9T A;  1RF0 B;  1LTJ C;  1FID A;  1FZD A;  1FZC B;  3H32 B;  3HUS C;  4JYO X;  1RE4 B;  2J3O A;  2FFD B;  1Z3U A;  2J60 A;  2OYI B;  2HLO C;  3E1I C;  2GY7 A;  2HPC B;  1M1J C;  2XNX B;  4ZFG A;  2J0H A;  1FZF B;  1RF1 C;  2J61 B;  2J61 A;  2J0G A;  2FIB A;  1N86 B;  4R9J A;  2H43 C;  1LWU C;  1Z3S A;  2Z4E C;  1LTJ B;  3GHG C;  1RE3 C;  2Q9I C;  1JC9 A;  3BVH C;  2JHK F;  3HUS B;  1FZE C;  2HOD C;  2J0Y A;  2JHM F;  1N73 C;  2H43 B;  2Z4E B;  2HLO B;  1FZG C;  2J5Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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