2JHLF

Structure of globular heads of m-ficolin complexed with sialic acid
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Sugar binding protein
source organism Homo sapiens
publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule keywords FICOLIN-1
total genus 75
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhlF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhlF02
4NYTA 3E1IB 2J0GA 4ZFGA 1N73B 4M7HA 2HODB 3E1IC 4JYOX 2OYIC 1N73C 1LT9B 2JHIF 2OYHC 2HODC 1FZFC 2HPCB 2J64A 1LT9C 2J3GA 4R9JA 1FIDA 2FIBA 1RF0B 1Z3SA 2J60A 2JHKF 2WNPF 1FZCC 1FICA 1RF0C 2XNXB 1FZGC 2H43C 1FIBA 2Z4EB 1FZAC 2J3FD 2XNXC 1FZBB 2J5ZA 2HLOB 1LWUB 1RF1B 2J0HA 2Q9IB 2HLOC 2J3OA 2FFDB 3H32B 2HPCC 4M7FA 1M1JB 2J2PA 3GHGC 2Q9IC 1RE4B 1FZEB 3H32C 1M1JC 2J61B 1RE3B 2Z4EC 2J1GA 3FIBA 2D39A 3HUSB 2GY7A 3BVHB 1Z3UA 1FZBC 1LTJB 1FZDA 2J0YA 1LWUC 1N86B 2OYIB 2JHMF 3HUSC 1RF1C 2OYHB 4R9TA 3BVHC 1LTJC 2FFDC 2JHHC 1N86C 2J61A 1FZFB 2JHLF 1RE4C 1FZEC 4EPUA 1FZCB 2J3FA 4JZCA 1FZGB 2J3UA 2H43B 1RE3C 1JC9A 1FZAB
chains in the Genus database with same CATH superfamily
4NYTA 3E1IB 2J0GA 4ZFGA 1N73B 4M7HA 2HODB 3E1IC 4JYOX 2OYIC 1N73C 1LT9B 2JHIF 2OYHC 2HODC 1FZFC 2HPCB 2J64A 1LT9C 2J3GA 4R9JA 1FIDA 2FIBA 1RF0B 1Z3SA 2J60A 2JHKF 2WNPF 1FZCC 1FICA 1RF0C 2XNXB 1FZGC 2H43C 1FIBA 2Z4EB 1FZAC 2J3FD 2XNXC 1FZBB 2J5ZA 2HLOB 1LWUB 1RF1B 2J0HA 3GHGB 2Q9IB 2HLOC 2J3OA 2FFDB 3H32B 2HPCC 4M7FA 1M1JB 2J2PA 3GHGC 2Q9IC 1RE4B 1FZEB 3H32C 1M1JC 2J61B 1RE3B 2Z4EC 2J1GA 3FIBA 2D39A 3HUSB 2GY7A 3BVHB 1Z3UA 1FZBC 1LTJB 1FZDA 2J0YA 1LWUC 1N86B 2OYIB 2JHMF 3HUSC 1RF1C 2OYHB 4R9TA 3BVHC 1LTJC 2FFDC 2JHHC 1N86C 2J61A 1FZFB 2JHLF 1RE4C 1FZEC 4EPUA 1FZCB 2J3FA 4JZCA 1FZGB 2J3UA 2H43B 1RE3C 1JC9A 1FZAB
chains in the Genus database with same CATH topology
4NYTA 3E1IB 2J0GA 4ZFGA 1N73B 4M7HA 2HODB 3E1IC 4JYOX 2OYIC 1N73C 1LT9B 2JHIF 2OYHC 2HODC 1FZFC 2HPCB 2J64A 1LT9C 2J3GA 4R9JA 1FIDA 2FIBA 1RF0B 1Z3SA 2J60A 2JHKF 2WNPF 1FZCC 1FICA 1RF0C 2XNXB 1FZGC 2H43C 1FIBA 2Z4EB 1FZAC 2J3FD 2XNXC 1FZBB 2J5ZA 2HLOB 1LWUB 1RF1B 2J0HA 2Q9IB 2HLOC 2J3OA 2FFDB 3H32B 2HPCC 4M7FA 1M1JB 2J2PA 3GHGC 2Q9IC 1RE4B 1FZEB 3H32C 1M1JC 2J61B 1RE3B 2Z4EC 2J1GA 3FIBA 2D39A 3HUSB 2GY7A 3BVHB 1Z3UA 1FZBC 1LTJB 1FZDA 2J0YA 1LWUC 1N86B 2OYIB 2JHMF 3HUSC 1RF1C 2OYHB 4R9TA 3BVHC 1LTJC 2FFDC 2JHHC 1N86C 2J61A 1FZFB 2JHLF 1RE4C 1FZEC 4EPUA 1FZCB 2J3FA 4JZCA 1FZGB 2J3UA 2H43B 1RE3C 1JC9A 1FZAB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NYT A;  3E1I B;  2J0G A;  4ZFG A;  1N73 B;  4M7H A;  2HOD B;  3E1I C;  4JYO X;  2OYI C;  1N73 C;  1LT9 B;  2JHI F;  2OYH C;  2HOD C;  1FZF C;  2HPC B;  2J64 A;  1LT9 C;  2J3G A;  4R9J A;  1FID A;  2FIB A;  1RF0 B;  1Z3S A;  2J60 A;  2JHK F;  2WNP F;  1FZC C;  1FIC A;  1RF0 C;  2XNX B;  1FZG C;  2H43 C;  1FIB A;  2Z4E B;  1FZA C;  2J3F D;  2XNX C;  1FZB B;  2J5Z A;  2HLO B;  1LWU B;  1RF1 B;  2J0H A;  2Q9I B;  2HLO C;  2J3O A;  2FFD B;  3H32 B;  2HPC C;  4M7F A;  1M1J B;  2J2P A;  3GHG C;  2Q9I C;  1RE4 B;  1FZE B;  3H32 C;  1M1J C;  2J61 B;  1RE3 B;  2Z4E C;  2J1G A;  3FIB A;  2D39 A;  3HUS B;  2GY7 A;  3BVH B;  1Z3U A;  1FZB C;  1LTJ B;  1FZD A;  2J0Y A;  1LWU C;  1N86 B;  2OYI B;  2JHM F;  3HUS C;  1RF1 C;  2OYH B;  4R9T A;  3BVH C;  1LTJ C;  2FFD C;  2JHH C;  1N86 C;  2J61 A;  1FZF B;  2JHL F;  1RE4 C;  1FZE C;  4EPU A;  1FZC B;  2J3F A;  4JZC A;  1FZG B;  2J3U A;  2H43 B;  1RE3 C;  1JC9 A;  1FZA B; 
#chains in the Genus database with same CATH topology
 4NYT A;  3E1I B;  2J0G A;  4ZFG A;  1N73 B;  4M7H A;  2HOD B;  3E1I C;  4JYO X;  2OYI C;  1N73 C;  1LT9 B;  2JHI F;  2OYH C;  2HOD C;  1FZF C;  2HPC B;  2J64 A;  1LT9 C;  2J3G A;  4R9J A;  1FID A;  2FIB A;  1RF0 B;  1Z3S A;  2J60 A;  2JHK F;  2WNP F;  1FZC C;  1FIC A;  1RF0 C;  2XNX B;  1FZG C;  2H43 C;  1FIB A;  2Z4E B;  1FZA C;  2J3F D;  2XNX C;  1FZB B;  2J5Z A;  2HLO B;  1LWU B;  1RF1 B;  2J0H A;  3GHG B;  2Q9I B;  2HLO C;  2J3O A;  2FFD B;  3H32 B;  2HPC C;  4M7F A;  1M1J B;  2J2P A;  3GHG C;  2Q9I C;  1RE4 B;  1FZE B;  3H32 C;  1M1J C;  2J61 B;  1RE3 B;  2Z4E C;  2J1G A;  3FIB A;  2D39 A;  3HUS B;  2GY7 A;  3BVH B;  1Z3U A;  1FZB C;  1LTJ B;  1FZD A;  2J0Y A;  1LWU C;  1N86 B;  2OYI B;  2JHM F;  3HUS C;  1RF1 C;  2OYH B;  4R9T A;  3BVH C;  1LTJ C;  2FFD C;  2JHH C;  1N86 C;  2J61 A;  1FZF B;  2JHL F;  1RE4 C;  1FZE C;  4EPU A;  1FZC B;  2J3F A;  4JZC A;  1FZG B;  2J3U A;  2H43 B;  1RE3 C;  1JC9 A;  1FZA B; 
#chains in the Genus database with same CATH homology
 4NYT A;  3E1I B;  2J0G A;  4ZFG A;  1N73 B;  4M7H A;  2HOD B;  3E1I C;  4JYO X;  2OYI C;  1N73 C;  1LT9 B;  2JHI F;  2OYH C;  2HOD C;  1FZF C;  2HPC B;  2J64 A;  1LT9 C;  2J3G A;  4R9J A;  1FID A;  2FIB A;  1RF0 B;  1Z3S A;  2J60 A;  2JHK F;  2WNP F;  1FZC C;  1FIC A;  1RF0 C;  2XNX B;  1FZG C;  2H43 C;  1FIB A;  2Z4E B;  1FZA C;  2J3F D;  2XNX C;  1FZB B;  2J5Z A;  2HLO B;  1LWU B;  1RF1 B;  2J0H A;  2Q9I B;  2HLO C;  2J3O A;  2FFD B;  3H32 B;  2HPC C;  4M7F A;  1M1J B;  2J2P A;  3GHG C;  2Q9I C;  1RE4 B;  1FZE B;  3H32 C;  1M1J C;  2J61 B;  1RE3 B;  2Z4E C;  2J1G A;  3FIB A;  2D39 A;  3HUS B;  2GY7 A;  3BVH B;  1Z3U A;  1FZB C;  1LTJ B;  1FZD A;  2J0Y A;  1LWU C;  1N86 B;  2OYI B;  2JHM F;  3HUS C;  1RF1 C;  2OYH B;  4R9T A;  3BVH C;  1LTJ C;  2FFD C;  2JHH C;  1N86 C;  2J61 A;  1FZF B;  2JHL F;  1RE4 C;  1FZE C;  4EPU A;  1FZC B;  2J3F A;  4JZC A;  1FZG B;  2J3U A;  2H43 B;  1RE3 C;  1JC9 A;  1FZA B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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