2Q9IB

Crystal structure of d-dimer from human fibrin complexed with met-his-arg-pro-tyr-amide.
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 90
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2q9iB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2q9iB02
4NYTA 1LTJC 2HODC 1RE3B 1M1JC 1N86C 4ZFGA 4M7HA 3HUSB 1RF1C 1FZAC 2H43C 1LWUB 2J5ZA 2J60A 3H32B 1FZCC 1N73C 2J0YA 2OYIB 2OYHB 1FICA 1RF0B 2HLOB 2J1GA 3E1IB 2J2PA 2Z4EC 1Z3UA 2JHHC 1LT9C 2HPCC 1FZEB 2FFDC 1FZFC 2J0HA 1FZGC 3BVHB 1RE3C 1JC9A 3HUSC 1LWUC 2XNXB 2J0GA 2OYIC 2OYHC 2HLOC 1FZCB 1Z3SA 4JYOX 1RE4B 3E1IC 1FIBA 2FIBA 4M7FA 1FZBB 2D39A 2Q9IB 1FZEC 2Z4EB 2GY7A 2J3UA 4R9JA 2J61A 3FIBA 2JHIF 2JHMF 3H32C 2J64A 1FIDA 1LTJB 2HODB 3BVHC 1M1JB 1N86B 1RF1B 1FZAB 2J3FD 2JHLF 4R9TA 2H43B 2XNXC 1FZGB 1RF0C 1N73B 1FZDA 2J3OA 3GHGC 2J61B 2WNPF 1RE4C 1LT9B 1FZBC 2HPCB 2Q9IC 2J3GA 2J3FA 2FFDB 4EPUA 2JHKF 4JZCA 1FZFB
chains in the Genus database with same CATH superfamily
4NYTA 1LTJC 2HODC 1RE3B 1M1JC 1N86C 4ZFGA 4M7HA 3HUSB 1RF1C 1FZAC 2H43C 1LWUB 2J5ZA 2J60A 3H32B 1FZCC 1N73C 2J0YA 2OYIB 2OYHB 1FICA 1RF0B 2HLOB 2J1GA 3E1IB 2J2PA 2Z4EC 1Z3UA 2JHHC 1LT9C 2HPCC 1FZEB 2FFDC 1FZFC 2J0HA 1FZGC 3BVHB 1RE3C 1JC9A 3HUSC 1LWUC 2XNXB 2J0GA 2OYIC 3GHGB 2OYHC 2HLOC 1FZCB 1Z3SA 4JYOX 1RE4B 3E1IC 1FIBA 2FIBA 4M7FA 1FZBB 2D39A 2Q9IB 1FZEC 2Z4EB 2GY7A 2J3UA 4R9JA 2J61A 3FIBA 2JHIF 2JHMF 3H32C 2J64A 1FIDA 1LTJB 2HODB 3BVHC 1M1JB 1N86B 1RF1B 1FZAB 2J3FD 2JHLF 4R9TA 2H43B 2XNXC 1FZGB 1RF0C 1N73B 1FZDA 2J3OA 3GHGC 2J61B 2WNPF 1RE4C 1LT9B 1FZBC 2HPCB 2Q9IC 2J3GA 2J3FA 2FFDB 4EPUA 2JHKF 4JZCA 1FZFB
chains in the Genus database with same CATH topology
4NYTA 1LTJC 2HODC 1RE3B 1M1JC 1N86C 4ZFGA 4M7HA 3HUSB 1RF1C 1FZAC 2H43C 1LWUB 2J5ZA 2J60A 3H32B 1FZCC 1N73C 2J0YA 2OYIB 2OYHB 1FICA 1RF0B 2HLOB 2J1GA 3E1IB 2J2PA 2Z4EC 1Z3UA 2JHHC 1LT9C 2HPCC 1FZEB 2FFDC 1FZFC 2J0HA 1FZGC 3BVHB 1RE3C 1JC9A 3HUSC 1LWUC 2XNXB 2J0GA 2OYIC 2OYHC 2HLOC 1FZCB 1Z3SA 4JYOX 1RE4B 3E1IC 1FIBA 2FIBA 4M7FA 1FZBB 2D39A 2Q9IB 1FZEC 2Z4EB 2GY7A 2J3UA 4R9JA 2J61A 3FIBA 2JHIF 2JHMF 3H32C 2J64A 1FIDA 1LTJB 2HODB 3BVHC 1M1JB 1N86B 1RF1B 1FZAB 2J3FD 2JHLF 4R9TA 2H43B 2XNXC 1FZGB 1RF0C 1N73B 1FZDA 2J3OA 3GHGC 2J61B 2WNPF 1RE4C 1LT9B 1FZBC 2HPCB 2Q9IC 2J3GA 2J3FA 2FFDB 4EPUA 2JHKF 4JZCA 1FZFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NYT A;  1LTJ C;  2HOD C;  1RE3 B;  1M1J C;  1N86 C;  4ZFG A;  4M7H A;  3HUS B;  1RF1 C;  1FZA C;  2H43 C;  1LWU B;  2J5Z A;  2J60 A;  3H32 B;  1FZC C;  1N73 C;  2J0Y A;  2OYI B;  2OYH B;  1FIC A;  1RF0 B;  2HLO B;  2J1G A;  3E1I B;  2J2P A;  2Z4E C;  1Z3U A;  2JHH C;  1LT9 C;  2HPC C;  1FZE B;  2FFD C;  1FZF C;  2J0H A;  1FZG C;  3BVH B;  1RE3 C;  1JC9 A;  3HUS C;  1LWU C;  2XNX B;  2J0G A;  2OYI C;  2OYH C;  2HLO C;  1FZC B;  1Z3S A;  4JYO X;  1RE4 B;  3E1I C;  1FIB A;  2FIB A;  4M7F A;  1FZB B;  2D39 A;  2Q9I B;  1FZE C;  2Z4E B;  2GY7 A;  2J3U A;  4R9J A;  2J61 A;  3FIB A;  2JHI F;  2JHM F;  3H32 C;  2J64 A;  1FID A;  1LTJ B;  2HOD B;  3BVH C;  1M1J B;  1N86 B;  1RF1 B;  1FZA B;  2J3F D;  2JHL F;  4R9T A;  2H43 B;  2XNX C;  1FZG B;  1RF0 C;  1N73 B;  1FZD A;  2J3O A;  3GHG C;  2J61 B;  2WNP F;  1RE4 C;  1LT9 B;  1FZB C;  2HPC B;  2Q9I C;  2J3G A;  2J3F A;  2FFD B;  4EPU A;  2JHK F;  4JZC A;  1FZF B; 
#chains in the Genus database with same CATH topology
 4NYT A;  1LTJ C;  2HOD C;  1RE3 B;  1M1J C;  1N86 C;  4ZFG A;  4M7H A;  3HUS B;  1RF1 C;  1FZA C;  2H43 C;  1LWU B;  2J5Z A;  2J60 A;  3H32 B;  1FZC C;  1N73 C;  2J0Y A;  2OYI B;  2OYH B;  1FIC A;  1RF0 B;  2HLO B;  2J1G A;  3E1I B;  2J2P A;  2Z4E C;  1Z3U A;  2JHH C;  1LT9 C;  2HPC C;  1FZE B;  2FFD C;  1FZF C;  2J0H A;  1FZG C;  3BVH B;  1RE3 C;  1JC9 A;  3HUS C;  1LWU C;  2XNX B;  2J0G A;  2OYI C;  3GHG B;  2OYH C;  2HLO C;  1FZC B;  1Z3S A;  4JYO X;  1RE4 B;  3E1I C;  1FIB A;  2FIB A;  4M7F A;  1FZB B;  2D39 A;  2Q9I B;  1FZE C;  2Z4E B;  2GY7 A;  2J3U A;  4R9J A;  2J61 A;  3FIB A;  2JHI F;  2JHM F;  3H32 C;  2J64 A;  1FID A;  1LTJ B;  2HOD B;  3BVH C;  1M1J B;  1N86 B;  1RF1 B;  1FZA B;  2J3F D;  2JHL F;  4R9T A;  2H43 B;  2XNX C;  1FZG B;  1RF0 C;  1N73 B;  1FZD A;  2J3O A;  3GHG C;  2J61 B;  2WNP F;  1RE4 C;  1LT9 B;  1FZB C;  2HPC B;  2Q9I C;  2J3G A;  2J3F A;  2FFD B;  4EPU A;  2JHK F;  4JZC A;  1FZF B; 
#chains in the Genus database with same CATH homology
 4NYT A;  1LTJ C;  2HOD C;  1RE3 B;  1M1J C;  1N86 C;  4ZFG A;  4M7H A;  3HUS B;  1RF1 C;  1FZA C;  2H43 C;  1LWU B;  2J5Z A;  2J60 A;  3H32 B;  1FZC C;  1N73 C;  2J0Y A;  2OYI B;  2OYH B;  1FIC A;  1RF0 B;  2HLO B;  2J1G A;  3E1I B;  2J2P A;  2Z4E C;  1Z3U A;  2JHH C;  1LT9 C;  2HPC C;  1FZE B;  2FFD C;  1FZF C;  2J0H A;  1FZG C;  3BVH B;  1RE3 C;  1JC9 A;  3HUS C;  1LWU C;  2XNX B;  2J0G A;  2OYI C;  2OYH C;  2HLO C;  1FZC B;  1Z3S A;  4JYO X;  1RE4 B;  3E1I C;  1FIB A;  2FIB A;  4M7F A;  1FZB B;  2D39 A;  2Q9I B;  1FZE C;  2Z4E B;  2GY7 A;  2J3U A;  4R9J A;  2J61 A;  3FIB A;  2JHI F;  2JHM F;  3H32 C;  2J64 A;  1FID A;  1LTJ B;  2HOD B;  3BVH C;  1M1J B;  1N86 B;  1RF1 B;  1FZA B;  2J3F D;  2JHL F;  4R9T A;  2H43 B;  2XNX C;  1FZG B;  1RF0 C;  1N73 B;  1FZD A;  2J3O A;  3GHG C;  2J61 B;  2WNP F;  1RE4 C;  1LT9 B;  1FZB C;  2HPC B;  2Q9I C;  2J3G A;  2J3F A;  2FFD B;  4EPU A;  2JHK F;  4JZC A;  1FZF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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