2Q9IC

Crystal structure of d-dimer from human fibrin complexed with met-his-arg-pro-tyr-amide.
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 80
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2q9iC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2q9iC02
4ZFGA 2Q9IB 2J61B 1RE4B 4M7FA 3HUSB 1FZAB 1N86C 3FIBA 4JYOX 2J5ZA 1Z3UA 2Z4EB 2J0GA 2FIBA 3GHGC 2JHIF 4R9TA 1LT9B 1LWUB 1FZFB 2HPCB 2J3FD 1FIDA 3BVHC 4M7HA 2FFDB 1FIBA 1FZGC 2XNXC 2JHMF 4NYTA 2J0HA 1RF0C 1RE3C 1Z3SA 4EPUA 2OYHC 2OYIC 3H32C 1FZGB 2J1GA 1JC9A 2HLOC 2JHHC 2H43C 1N73C 1FZBC 2J3UA 2J61A 1FZDA 1RF0B 2GY7A 2J64A 2J3FA 1FZEC 1N86B 1RF1C 1LTJC 3H32B 2JHLF 2HLOB 1FZCC 2Q9IC 1RF1B 1LTJB 1FICA 1RE4C 3BVHB 2J0YA 3HUSC 1FZCB 2XNXB 1FZAC 2HODC 2WNPF 3E1IC 4R9JA 1RE3B 2JHKF 2OYHB 2J3GA 2Z4EC 2OYIB 1M1JC 2J60A 2HODB 2H43B 1LT9C 1N73B 3E1IB 1FZBB 1LWUC 4JZCA 2HPCC 1FZFC 2J3OA 2D39A 1FZEB 1M1JB 2FFDC 2J2PA
chains in the Genus database with same CATH superfamily
4ZFGA 2Q9IB 2J61B 1RE4B 4M7FA 3HUSB 1FZAB 1N86C 3FIBA 4JYOX 2J5ZA 1Z3UA 2Z4EB 2J0GA 2FIBA 3GHGC 2JHIF 4R9TA 1LT9B 1LWUB 1FZFB 2HPCB 2J3FD 1FIDA 3BVHC 3GHGB 4M7HA 2FFDB 1FIBA 1FZGC 2XNXC 2JHMF 4NYTA 2J0HA 1RF0C 1RE3C 1Z3SA 4EPUA 2OYHC 2OYIC 3H32C 1FZGB 2J1GA 1JC9A 2HLOC 2JHHC 2H43C 1N73C 1FZBC 2J3UA 2J61A 1FZDA 1RF0B 2GY7A 2J64A 2J3FA 1FZEC 1N86B 1RF1C 1LTJC 3H32B 2JHLF 2HLOB 1FZCC 2Q9IC 1RF1B 1LTJB 1FICA 1RE4C 3BVHB 2J0YA 3HUSC 1FZCB 2XNXB 1FZAC 2HODC 2WNPF 3E1IC 4R9JA 1RE3B 2JHKF 2OYHB 2J3GA 2Z4EC 2OYIB 1M1JC 2J60A 2HODB 2H43B 1LT9C 1N73B 3E1IB 1FZBB 1LWUC 4JZCA 2HPCC 1FZFC 2J3OA 2D39A 1FZEB 1M1JB 2FFDC 2J2PA
chains in the Genus database with same CATH topology
4ZFGA 2Q9IB 2J61B 1RE4B 4M7FA 3HUSB 1FZAB 1N86C 3FIBA 4JYOX 2J5ZA 1Z3UA 2Z4EB 2J0GA 2FIBA 3GHGC 2JHIF 4R9TA 1LT9B 1LWUB 1FZFB 2HPCB 2J3FD 1FIDA 3BVHC 4M7HA 2FFDB 1FIBA 1FZGC 2XNXC 2JHMF 4NYTA 2J0HA 1RF0C 1RE3C 1Z3SA 4EPUA 2OYHC 2OYIC 3H32C 1FZGB 2J1GA 1JC9A 2HLOC 2JHHC 2H43C 1N73C 1FZBC 2J3UA 2J61A 1FZDA 1RF0B 2GY7A 2J64A 2J3FA 1FZEC 1N86B 1RF1C 1LTJC 3H32B 2JHLF 2HLOB 1FZCC 2Q9IC 1RF1B 1LTJB 1FICA 1RE4C 3BVHB 2J0YA 3HUSC 1FZCB 2XNXB 1FZAC 2HODC 2WNPF 3E1IC 4R9JA 1RE3B 2JHKF 2OYHB 2J3GA 2Z4EC 2OYIB 1M1JC 2J60A 2HODB 2H43B 1LT9C 1N73B 3E1IB 1FZBB 1LWUC 4JZCA 2HPCC 1FZFC 2J3OA 2D39A 1FZEB 1M1JB 2FFDC 2J2PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZFG A;  2Q9I B;  2J61 B;  1RE4 B;  4M7F A;  3HUS B;  1FZA B;  1N86 C;  3FIB A;  4JYO X;  2J5Z A;  1Z3U A;  2Z4E B;  2J0G A;  2FIB A;  3GHG C;  2JHI F;  4R9T A;  1LT9 B;  1LWU B;  1FZF B;  2HPC B;  2J3F D;  1FID A;  3BVH C;  4M7H A;  2FFD B;  1FIB A;  1FZG C;  2XNX C;  2JHM F;  4NYT A;  2J0H A;  1RF0 C;  1RE3 C;  1Z3S A;  4EPU A;  2OYH C;  2OYI C;  3H32 C;  1FZG B;  2J1G A;  1JC9 A;  2HLO C;  2JHH C;  2H43 C;  1N73 C;  1FZB C;  2J3U A;  2J61 A;  1FZD A;  1RF0 B;  2GY7 A;  2J64 A;  2J3F A;  1FZE C;  1N86 B;  1RF1 C;  1LTJ C;  3H32 B;  2JHL F;  2HLO B;  1FZC C;  2Q9I C;  1RF1 B;  1LTJ B;  1FIC A;  1RE4 C;  3BVH B;  2J0Y A;  3HUS C;  1FZC B;  2XNX B;  1FZA C;  2HOD C;  2WNP F;  3E1I C;  4R9J A;  1RE3 B;  2JHK F;  2OYH B;  2J3G A;  2Z4E C;  2OYI B;  1M1J C;  2J60 A;  2HOD B;  2H43 B;  1LT9 C;  1N73 B;  3E1I B;  1FZB B;  1LWU C;  4JZC A;  2HPC C;  1FZF C;  2J3O A;  2D39 A;  1FZE B;  1M1J B;  2FFD C;  2J2P A; 
#chains in the Genus database with same CATH topology
 4ZFG A;  2Q9I B;  2J61 B;  1RE4 B;  4M7F A;  3HUS B;  1FZA B;  1N86 C;  3FIB A;  4JYO X;  2J5Z A;  1Z3U A;  2Z4E B;  2J0G A;  2FIB A;  3GHG C;  2JHI F;  4R9T A;  1LT9 B;  1LWU B;  1FZF B;  2HPC B;  2J3F D;  1FID A;  3BVH C;  3GHG B;  4M7H A;  2FFD B;  1FIB A;  1FZG C;  2XNX C;  2JHM F;  4NYT A;  2J0H A;  1RF0 C;  1RE3 C;  1Z3S A;  4EPU A;  2OYH C;  2OYI C;  3H32 C;  1FZG B;  2J1G A;  1JC9 A;  2HLO C;  2JHH C;  2H43 C;  1N73 C;  1FZB C;  2J3U A;  2J61 A;  1FZD A;  1RF0 B;  2GY7 A;  2J64 A;  2J3F A;  1FZE C;  1N86 B;  1RF1 C;  1LTJ C;  3H32 B;  2JHL F;  2HLO B;  1FZC C;  2Q9I C;  1RF1 B;  1LTJ B;  1FIC A;  1RE4 C;  3BVH B;  2J0Y A;  3HUS C;  1FZC B;  2XNX B;  1FZA C;  2HOD C;  2WNP F;  3E1I C;  4R9J A;  1RE3 B;  2JHK F;  2OYH B;  2J3G A;  2Z4E C;  2OYI B;  1M1J C;  2J60 A;  2HOD B;  2H43 B;  1LT9 C;  1N73 B;  3E1I B;  1FZB B;  1LWU C;  4JZC A;  2HPC C;  1FZF C;  2J3O A;  2D39 A;  1FZE B;  1M1J B;  2FFD C;  2J2P A; 
#chains in the Genus database with same CATH homology
 4ZFG A;  2Q9I B;  2J61 B;  1RE4 B;  4M7F A;  3HUS B;  1FZA B;  1N86 C;  3FIB A;  4JYO X;  2J5Z A;  1Z3U A;  2Z4E B;  2J0G A;  2FIB A;  3GHG C;  2JHI F;  4R9T A;  1LT9 B;  1LWU B;  1FZF B;  2HPC B;  2J3F D;  1FID A;  3BVH C;  4M7H A;  2FFD B;  1FIB A;  1FZG C;  2XNX C;  2JHM F;  4NYT A;  2J0H A;  1RF0 C;  1RE3 C;  1Z3S A;  4EPU A;  2OYH C;  2OYI C;  3H32 C;  1FZG B;  2J1G A;  1JC9 A;  2HLO C;  2JHH C;  2H43 C;  1N73 C;  1FZB C;  2J3U A;  2J61 A;  1FZD A;  1RF0 B;  2GY7 A;  2J64 A;  2J3F A;  1FZE C;  1N86 B;  1RF1 C;  1LTJ C;  3H32 B;  2JHL F;  2HLO B;  1FZC C;  2Q9I C;  1RF1 B;  1LTJ B;  1FIC A;  1RE4 C;  3BVH B;  2J0Y A;  3HUS C;  1FZC B;  2XNX B;  1FZA C;  2HOD C;  2WNP F;  3E1I C;  4R9J A;  1RE3 B;  2JHK F;  2OYH B;  2J3G A;  2Z4E C;  2OYI B;  1M1J C;  2J60 A;  2HOD B;  2H43 B;  1LT9 C;  1N73 B;  3E1I B;  1FZB B;  1LWU C;  4JZC A;  2HPC C;  1FZF C;  2J3O A;  2D39 A;  1FZE B;  1M1J B;  2FFD C;  2J2P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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