2Q9IC

Crystal structure of d-dimer from human fibrin complexed with met-his-arg-pro-tyr-amide.
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 80
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2q9iC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2q9iC02
1M1JB 2XNXC 1FZCB 2H43B 2Q9IC 3GHGC 2J60A 2OYIC 2XNXB 4M7FA 2WNPF 1RE4C 2Q9IB 2J3OA 1FIDA 2JHIF 1FZCC 3H32B 2OYIB 2J64A 1RE4B 1FZFB 2OYHC 1FZGC 2J3GA 1N73C 3HUSC 2HODB 2OYHB 4JZCA 2Z4EC 1FZEC 1FZGB 3H32C 2HPCC 1N73B 2HLOC 1FZFC 4JYOX 3HUSB 4NYTA 2Z4EB 1Z3SA 1FZEB 2D39A 2J1GA 2HODC 2HPCB 2HLOB 2JHHC 1LTJC 2J61A 2J5ZA 3BVHC 1Z3UA 1N86C 1FZBC 2J3UA 2J61B 1LWUC 1FZAC 1LTJB 1LT9B 1FICA 1RF1C 2FFDC 2JHMF 3BVHB 1N86B 1FZBB 1LWUB 1FZAB 1RF1B 4M7HA 2GY7A 4R9JA 2FFDB 4ZFGA 2J0YA 2J3FA 1LT9C 2J3FD 3FIBA 2J0HA 3E1IC 1JC9A 2J0GA 1RE3C 2FIBA 2JHKF 1RF0C 2JHLF 4R9TA 1FIBA 1FZDA 2J2PA 3E1IB 1M1JC 2H43C 1RE3B 1RF0B 4EPUA
chains in the Genus database with same CATH superfamily
1M1JB 2XNXC 1FZCB 2H43B 2Q9IC 3GHGC 2J60A 2OYIC 2XNXB 4M7FA 2WNPF 1RE4C 2Q9IB 2J3OA 3GHGB 1FIDA 2JHIF 1FZCC 3H32B 2OYIB 2J64A 1RE4B 1FZFB 2OYHC 1FZGC 2J3GA 1N73C 3HUSC 2HODB 2OYHB 4JZCA 2Z4EC 1FZEC 1FZGB 3H32C 2HPCC 1N73B 2HLOC 1FZFC 4JYOX 3HUSB 4NYTA 2Z4EB 1Z3SA 1FZEB 2D39A 2J1GA 2HODC 2HPCB 2HLOB 2JHHC 1LTJC 2J61A 2J5ZA 3BVHC 1Z3UA 1N86C 1FZBC 2J3UA 2J61B 1LWUC 1FZAC 1LTJB 1LT9B 1FICA 1RF1C 2FFDC 2JHMF 3BVHB 1N86B 1FZBB 1LWUB 1FZAB 1RF1B 4M7HA 2GY7A 4R9JA 2FFDB 4ZFGA 2J0YA 2J3FA 1LT9C 2J3FD 3FIBA 2J0HA 3E1IC 1JC9A 2J0GA 1RE3C 2FIBA 2JHKF 1RF0C 2JHLF 4R9TA 1FIBA 1FZDA 2J2PA 3E1IB 1M1JC 2H43C 1RE3B 1RF0B 4EPUA
chains in the Genus database with same CATH topology
1M1JB 2XNXC 1FZCB 2H43B 2Q9IC 3GHGC 2J60A 2OYIC 2XNXB 4M7FA 2WNPF 1RE4C 2Q9IB 2J3OA 1FIDA 2JHIF 1FZCC 3H32B 2OYIB 2J64A 1RE4B 1FZFB 2OYHC 1FZGC 2J3GA 1N73C 3HUSC 2HODB 2OYHB 4JZCA 2Z4EC 1FZEC 1FZGB 3H32C 2HPCC 1N73B 2HLOC 1FZFC 4JYOX 3HUSB 4NYTA 2Z4EB 1Z3SA 1FZEB 2D39A 2J1GA 2HODC 2HPCB 2HLOB 2JHHC 1LTJC 2J61A 2J5ZA 3BVHC 1Z3UA 1N86C 1FZBC 2J3UA 2J61B 1LWUC 1FZAC 1LTJB 1LT9B 1FICA 1RF1C 2FFDC 2JHMF 3BVHB 1N86B 1FZBB 1LWUB 1FZAB 1RF1B 4M7HA 2GY7A 4R9JA 2FFDB 4ZFGA 2J0YA 2J3FA 1LT9C 2J3FD 3FIBA 2J0HA 3E1IC 1JC9A 2J0GA 1RE3C 2FIBA 2JHKF 1RF0C 2JHLF 4R9TA 1FIBA 1FZDA 2J2PA 3E1IB 1M1JC 2H43C 1RE3B 1RF0B 4EPUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M1J B;  2XNX C;  1FZC B;  2H43 B;  2Q9I C;  3GHG C;  2J60 A;  2OYI C;  2XNX B;  4M7F A;  2WNP F;  1RE4 C;  2Q9I B;  2J3O A;  1FID A;  2JHI F;  1FZC C;  3H32 B;  2OYI B;  2J64 A;  1RE4 B;  1FZF B;  2OYH C;  1FZG C;  2J3G A;  1N73 C;  3HUS C;  2HOD B;  2OYH B;  4JZC A;  2Z4E C;  1FZE C;  1FZG B;  3H32 C;  2HPC C;  1N73 B;  2HLO C;  1FZF C;  4JYO X;  3HUS B;  4NYT A;  2Z4E B;  1Z3S A;  1FZE B;  2D39 A;  2J1G A;  2HOD C;  2HPC B;  2HLO B;  2JHH C;  1LTJ C;  2J61 A;  2J5Z A;  3BVH C;  1Z3U A;  1N86 C;  1FZB C;  2J3U A;  2J61 B;  1LWU C;  1FZA C;  1LTJ B;  1LT9 B;  1FIC A;  1RF1 C;  2FFD C;  2JHM F;  3BVH B;  1N86 B;  1FZB B;  1LWU B;  1FZA B;  1RF1 B;  4M7H A;  2GY7 A;  4R9J A;  2FFD B;  4ZFG A;  2J0Y A;  2J3F A;  1LT9 C;  2J3F D;  3FIB A;  2J0H A;  3E1I C;  1JC9 A;  2J0G A;  1RE3 C;  2FIB A;  2JHK F;  1RF0 C;  2JHL F;  4R9T A;  1FIB A;  1FZD A;  2J2P A;  3E1I B;  1M1J C;  2H43 C;  1RE3 B;  1RF0 B;  4EPU A; 
#chains in the Genus database with same CATH topology
 1M1J B;  2XNX C;  1FZC B;  2H43 B;  2Q9I C;  3GHG C;  2J60 A;  2OYI C;  2XNX B;  4M7F A;  2WNP F;  1RE4 C;  2Q9I B;  2J3O A;  3GHG B;  1FID A;  2JHI F;  1FZC C;  3H32 B;  2OYI B;  2J64 A;  1RE4 B;  1FZF B;  2OYH C;  1FZG C;  2J3G A;  1N73 C;  3HUS C;  2HOD B;  2OYH B;  4JZC A;  2Z4E C;  1FZE C;  1FZG B;  3H32 C;  2HPC C;  1N73 B;  2HLO C;  1FZF C;  4JYO X;  3HUS B;  4NYT A;  2Z4E B;  1Z3S A;  1FZE B;  2D39 A;  2J1G A;  2HOD C;  2HPC B;  2HLO B;  2JHH C;  1LTJ C;  2J61 A;  2J5Z A;  3BVH C;  1Z3U A;  1N86 C;  1FZB C;  2J3U A;  2J61 B;  1LWU C;  1FZA C;  1LTJ B;  1LT9 B;  1FIC A;  1RF1 C;  2FFD C;  2JHM F;  3BVH B;  1N86 B;  1FZB B;  1LWU B;  1FZA B;  1RF1 B;  4M7H A;  2GY7 A;  4R9J A;  2FFD B;  4ZFG A;  2J0Y A;  2J3F A;  1LT9 C;  2J3F D;  3FIB A;  2J0H A;  3E1I C;  1JC9 A;  2J0G A;  1RE3 C;  2FIB A;  2JHK F;  1RF0 C;  2JHL F;  4R9T A;  1FIB A;  1FZD A;  2J2P A;  3E1I B;  1M1J C;  2H43 C;  1RE3 B;  1RF0 B;  4EPU A; 
#chains in the Genus database with same CATH homology
 1M1J B;  2XNX C;  1FZC B;  2H43 B;  2Q9I C;  3GHG C;  2J60 A;  2OYI C;  2XNX B;  4M7F A;  2WNP F;  1RE4 C;  2Q9I B;  2J3O A;  1FID A;  2JHI F;  1FZC C;  3H32 B;  2OYI B;  2J64 A;  1RE4 B;  1FZF B;  2OYH C;  1FZG C;  2J3G A;  1N73 C;  3HUS C;  2HOD B;  2OYH B;  4JZC A;  2Z4E C;  1FZE C;  1FZG B;  3H32 C;  2HPC C;  1N73 B;  2HLO C;  1FZF C;  4JYO X;  3HUS B;  4NYT A;  2Z4E B;  1Z3S A;  1FZE B;  2D39 A;  2J1G A;  2HOD C;  2HPC B;  2HLO B;  2JHH C;  1LTJ C;  2J61 A;  2J5Z A;  3BVH C;  1Z3U A;  1N86 C;  1FZB C;  2J3U A;  2J61 B;  1LWU C;  1FZA C;  1LTJ B;  1LT9 B;  1FIC A;  1RF1 C;  2FFD C;  2JHM F;  3BVH B;  1N86 B;  1FZB B;  1LWU B;  1FZA B;  1RF1 B;  4M7H A;  2GY7 A;  4R9J A;  2FFD B;  4ZFG A;  2J0Y A;  2J3F A;  1LT9 C;  2J3F D;  3FIB A;  2J0H A;  3E1I C;  1JC9 A;  2J0G A;  1RE3 C;  2FIB A;  2JHK F;  1RF0 C;  2JHL F;  4R9T A;  1FIB A;  1FZD A;  2J2P A;  3E1I B;  1M1J C;  2H43 C;  1RE3 B;  1RF0 B;  4EPU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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