2WNPF

M-ficolin mutant y271f
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESFANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Carbohydrate Recognition Properties of Human Ficolins: Glycan Array Screening Reveals the Sialic Acid Binding Specificity of M-Ficolin.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 76
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2009-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2wnpF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2wnpF02
1LT9C 3FIBA 2XNXB 1FZCC 2J3FD 1FZEC 1LWUB 2JHHC 1RF1C 1FZEB 4JYOX 1LTJB 1RE4B 2GY7A 2J5ZA 2Q9IC 1RE3B 3BVHC 1Z3SA 4M7HA 2HODC 3HUSC 2Q9IB 3BVHB 2D39A 2HODB 2JHMF 3HUSB 2JHLF 1N86B 4R9JA 4M7FA 1LWUC 2FIBA 1LTJC 1RE4C 1FIBA 2J0YA 1FZBC 2FFDB 2J1GA 1JC9A 3E1IC 1FZBB 1FZGB 2J64A 1FZFC 1RE3C 3E1IB 4ZFGA 2J0GA 2HPCB 1FZFB 2Z4EB 2OYHC 3GHGC 2J61A 1RF0C 1N86C 2OYHB 4R9TA 1RF0B 4JZCA 2JHIF 1FICA 1N73C 2FFDC 2WNPF 1N73B 3H32C 1FZGC 2OYIB 2HLOC 3H32B 2J3GA 2HPCC 2Z4EC 1M1JC 2J3OA 2H43C 2J2PA 2HLOB 2J0HA 1M1JB 2H43B 1Z3UA 1FZDA 1LT9B 1FIDA 1FZCB 4NYTA 1RF1B 2J61B 2JHKF 2OYIC 2J3FA 1FZAC 1FZAB 4EPUA 2J60A 2XNXC 2J3UA
chains in the Genus database with same CATH superfamily
1LT9C 3FIBA 2XNXB 1FZCC 2J3FD 1FZEC 1LWUB 2JHHC 1RF1C 1FZEB 4JYOX 1LTJB 1RE4B 2GY7A 2J5ZA 2Q9IC 1RE3B 3BVHC 1Z3SA 4M7HA 2HODC 3HUSC 2Q9IB 3BVHB 2D39A 2HODB 2JHMF 3GHGB 3HUSB 2JHLF 1N86B 4R9JA 4M7FA 1LWUC 2FIBA 1LTJC 1RE4C 1FIBA 2J0YA 1FZBC 2FFDB 2J1GA 1JC9A 3E1IC 1FZBB 1FZGB 2J64A 1FZFC 1RE3C 3E1IB 4ZFGA 2J0GA 2HPCB 1FZFB 2Z4EB 2OYHC 3GHGC 2J61A 1RF0C 1N86C 2OYHB 4R9TA 1RF0B 4JZCA 2JHIF 1FICA 1N73C 2FFDC 2WNPF 1N73B 3H32C 1FZGC 2OYIB 2HLOC 3H32B 2J3GA 2HPCC 2Z4EC 1M1JC 2J3OA 2H43C 2J2PA 2HLOB 2J0HA 1M1JB 2H43B 1Z3UA 1FZDA 1LT9B 1FIDA 1FZCB 4NYTA 1RF1B 2J61B 2JHKF 2OYIC 2J3FA 1FZAC 1FZAB 4EPUA 2J60A 2XNXC 2J3UA
chains in the Genus database with same CATH topology
1LT9C 3FIBA 2XNXB 1FZCC 2J3FD 1FZEC 1LWUB 2JHHC 1RF1C 1FZEB 4JYOX 1LTJB 1RE4B 2GY7A 2J5ZA 2Q9IC 1RE3B 3BVHC 1Z3SA 4M7HA 2HODC 3HUSC 2Q9IB 3BVHB 2D39A 2HODB 2JHMF 3HUSB 2JHLF 1N86B 4R9JA 4M7FA 1LWUC 2FIBA 1LTJC 1RE4C 1FIBA 2J0YA 1FZBC 2FFDB 2J1GA 1JC9A 3E1IC 1FZBB 1FZGB 2J64A 1FZFC 1RE3C 3E1IB 4ZFGA 2J0GA 2HPCB 1FZFB 2Z4EB 2OYHC 3GHGC 2J61A 1RF0C 1N86C 2OYHB 4R9TA 1RF0B 4JZCA 2JHIF 1FICA 1N73C 2FFDC 2WNPF 1N73B 3H32C 1FZGC 2OYIB 2HLOC 3H32B 2J3GA 2HPCC 2Z4EC 1M1JC 2J3OA 2H43C 2J2PA 2HLOB 2J0HA 1M1JB 2H43B 1Z3UA 1FZDA 1LT9B 1FIDA 1FZCB 4NYTA 1RF1B 2J61B 2JHKF 2OYIC 2J3FA 1FZAC 1FZAB 4EPUA 2J60A 2XNXC 2J3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LT9 C;  3FIB A;  2XNX B;  1FZC C;  2J3F D;  1FZE C;  1LWU B;  2JHH C;  1RF1 C;  1FZE B;  4JYO X;  1LTJ B;  1RE4 B;  2GY7 A;  2J5Z A;  2Q9I C;  1RE3 B;  3BVH C;  1Z3S A;  4M7H A;  2HOD C;  3HUS C;  2Q9I B;  3BVH B;  2D39 A;  2HOD B;  2JHM F;  3HUS B;  2JHL F;  1N86 B;  4R9J A;  4M7F A;  1LWU C;  2FIB A;  1LTJ C;  1RE4 C;  1FIB A;  2J0Y A;  1FZB C;  2FFD B;  2J1G A;  1JC9 A;  3E1I C;  1FZB B;  1FZG B;  2J64 A;  1FZF C;  1RE3 C;  3E1I B;  4ZFG A;  2J0G A;  2HPC B;  1FZF B;  2Z4E B;  2OYH C;  3GHG C;  2J61 A;  1RF0 C;  1N86 C;  2OYH B;  4R9T A;  1RF0 B;  4JZC A;  2JHI F;  1FIC A;  1N73 C;  2FFD C;  2WNP F;  1N73 B;  3H32 C;  1FZG C;  2OYI B;  2HLO C;  3H32 B;  2J3G A;  2HPC C;  2Z4E C;  1M1J C;  2J3O A;  2H43 C;  2J2P A;  2HLO B;  2J0H A;  1M1J B;  2H43 B;  1Z3U A;  1FZD A;  1LT9 B;  1FID A;  1FZC B;  4NYT A;  1RF1 B;  2J61 B;  2JHK F;  2OYI C;  2J3F A;  1FZA C;  1FZA B;  4EPU A;  2J60 A;  2XNX C;  2J3U A; 
#chains in the Genus database with same CATH topology
 1LT9 C;  3FIB A;  2XNX B;  1FZC C;  2J3F D;  1FZE C;  1LWU B;  2JHH C;  1RF1 C;  1FZE B;  4JYO X;  1LTJ B;  1RE4 B;  2GY7 A;  2J5Z A;  2Q9I C;  1RE3 B;  3BVH C;  1Z3S A;  4M7H A;  2HOD C;  3HUS C;  2Q9I B;  3BVH B;  2D39 A;  2HOD B;  2JHM F;  3GHG B;  3HUS B;  2JHL F;  1N86 B;  4R9J A;  4M7F A;  1LWU C;  2FIB A;  1LTJ C;  1RE4 C;  1FIB A;  2J0Y A;  1FZB C;  2FFD B;  2J1G A;  1JC9 A;  3E1I C;  1FZB B;  1FZG B;  2J64 A;  1FZF C;  1RE3 C;  3E1I B;  4ZFG A;  2J0G A;  2HPC B;  1FZF B;  2Z4E B;  2OYH C;  3GHG C;  2J61 A;  1RF0 C;  1N86 C;  2OYH B;  4R9T A;  1RF0 B;  4JZC A;  2JHI F;  1FIC A;  1N73 C;  2FFD C;  2WNP F;  1N73 B;  3H32 C;  1FZG C;  2OYI B;  2HLO C;  3H32 B;  2J3G A;  2HPC C;  2Z4E C;  1M1J C;  2J3O A;  2H43 C;  2J2P A;  2HLO B;  2J0H A;  1M1J B;  2H43 B;  1Z3U A;  1FZD A;  1LT9 B;  1FID A;  1FZC B;  4NYT A;  1RF1 B;  2J61 B;  2JHK F;  2OYI C;  2J3F A;  1FZA C;  1FZA B;  4EPU A;  2J60 A;  2XNX C;  2J3U A; 
#chains in the Genus database with same CATH homology
 1LT9 C;  3FIB A;  2XNX B;  1FZC C;  2J3F D;  1FZE C;  1LWU B;  2JHH C;  1RF1 C;  1FZE B;  4JYO X;  1LTJ B;  1RE4 B;  2GY7 A;  2J5Z A;  2Q9I C;  1RE3 B;  3BVH C;  1Z3S A;  4M7H A;  2HOD C;  3HUS C;  2Q9I B;  3BVH B;  2D39 A;  2HOD B;  2JHM F;  3HUS B;  2JHL F;  1N86 B;  4R9J A;  4M7F A;  1LWU C;  2FIB A;  1LTJ C;  1RE4 C;  1FIB A;  2J0Y A;  1FZB C;  2FFD B;  2J1G A;  1JC9 A;  3E1I C;  1FZB B;  1FZG B;  2J64 A;  1FZF C;  1RE3 C;  3E1I B;  4ZFG A;  2J0G A;  2HPC B;  1FZF B;  2Z4E B;  2OYH C;  3GHG C;  2J61 A;  1RF0 C;  1N86 C;  2OYH B;  4R9T A;  1RF0 B;  4JZC A;  2JHI F;  1FIC A;  1N73 C;  2FFD C;  2WNP F;  1N73 B;  3H32 C;  1FZG C;  2OYI B;  2HLO C;  3H32 B;  2J3G A;  2HPC C;  2Z4E C;  1M1J C;  2J3O A;  2H43 C;  2J2P A;  2HLO B;  2J0H A;  1M1J B;  2H43 B;  1Z3U A;  1FZD A;  1LT9 B;  1FID A;  1FZC B;  4NYT A;  1RF1 B;  2J61 B;  2JHK F;  2OYI C;  2J3F A;  1FZA C;  1FZA B;  4EPU A;  2J60 A;  2XNX C;  2J3U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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