2XNXC

Bc1 fragment of streptococcal m1 protein in complex with human fibrinogen
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
302
structure length
302
Chain Sequence
EEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
pubmed doi rcsb
molecule tags Cell adhesion
source organism Streptococcus pyogenes
molecule keywords FIBRINOGEN ALPHA CHAIN
total genus 75
structure length 302
sequence length 302
chains with identical sequence F, I, L
ec nomenclature
pdb deposition date 2010-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2xnxC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2xnxC02
2WNPF 2Z4EB 1FZGC 2J61B 1N86C 1FZCB 1RE4B 2OYHC 2FFDB 2Q9IC 2JHMF 3H32C 3BVHC 2H43C 3GHGC 2J3OA 2J0GA 1LWUB 1FZBB 1FZEB 2J1GA 4JZCA 2J3GA 3E1IB 2HLOB 2FIBA 2J3FD 1RF1B 4R9JA 2OYHB 1FZFB 1LT9B 1RF0C 4M7FA 1M1JC 1FIBA 2HODC 2J3UA 1N73B 2XNXB 1LTJB 2J60A 3HUSC 2OYIB 2JHLF 1RE4C 4R9TA 1FZAB 2J0YA 2J2PA 1FZGB 4JYOX 1Z3UA 1N86B 2JHKF 2HPCC 2JHIF 4NYTA 2Q9IB 1RE3C 1FIDA 1RF0B 3H32B 2J5ZA 3BVHB 2H43B 2J0HA 2Z4EC 2D39A 1FZCC 1FICA 3HUSB 1RF1C 2FFDC 4ZFGA 3FIBA 1FZDA 1Z3SA 2JHHC 1FZFC 1LT9C 2J64A 4EPUA 1JC9A 2J3FA 4M7HA 2J61A 1N73C 2XNXC 1LTJC 2HPCB 2GY7A 1LWUC 2OYIC 1RE3B 1FZBC 1FZEC 1M1JB 2HODB 1FZAC 3E1IC 2HLOC
chains in the Genus database with same CATH superfamily
2WNPF 2Z4EB 1FZGC 2J61B 1N86C 1FZCB 1RE4B 2OYHC 2FFDB 2Q9IC 2JHMF 3H32C 3BVHC 2H43C 3GHGC 2J3OA 2J0GA 1LWUB 1FZBB 1FZEB 2J1GA 4JZCA 2J3GA 3E1IB 2HLOB 2FIBA 2J3FD 1RF1B 4R9JA 2OYHB 1FZFB 1LT9B 1RF0C 4M7FA 1M1JC 1FIBA 2HODC 2J3UA 1N73B 2XNXB 1LTJB 2J60A 3HUSC 2OYIB 2JHLF 1RE4C 4R9TA 1FZAB 2J0YA 2J2PA 1FZGB 4JYOX 1Z3UA 1N86B 2JHKF 2HPCC 2JHIF 4NYTA 2Q9IB 1RE3C 1FIDA 1RF0B 3H32B 2J5ZA 3BVHB 2H43B 3GHGB 2J0HA 2Z4EC 2D39A 1FZCC 1FICA 3HUSB 1RF1C 2FFDC 4ZFGA 3FIBA 1FZDA 1Z3SA 2JHHC 1FZFC 1LT9C 2J64A 4EPUA 1JC9A 2J3FA 4M7HA 2J61A 1N73C 2XNXC 1LTJC 2HPCB 2GY7A 1LWUC 2OYIC 1RE3B 1FZBC 1FZEC 1M1JB 2HODB 1FZAC 3E1IC 2HLOC
chains in the Genus database with same CATH topology
2WNPF 2Z4EB 1FZGC 2J61B 1N86C 1FZCB 1RE4B 2OYHC 2FFDB 2Q9IC 2JHMF 3H32C 3BVHC 2H43C 3GHGC 2J3OA 2J0GA 1LWUB 1FZBB 1FZEB 2J1GA 4JZCA 2J3GA 3E1IB 2HLOB 2FIBA 2J3FD 1RF1B 4R9JA 2OYHB 1FZFB 1LT9B 1RF0C 4M7FA 1M1JC 1FIBA 2HODC 2J3UA 1N73B 2XNXB 1LTJB 2J60A 3HUSC 2OYIB 2JHLF 1RE4C 4R9TA 1FZAB 2J0YA 2J2PA 1FZGB 4JYOX 1Z3UA 1N86B 2JHKF 2HPCC 2JHIF 4NYTA 2Q9IB 1RE3C 1FIDA 1RF0B 3H32B 2J5ZA 3BVHB 2H43B 2J0HA 2Z4EC 2D39A 1FZCC 1FICA 3HUSB 1RF1C 2FFDC 4ZFGA 3FIBA 1FZDA 1Z3SA 2JHHC 1FZFC 1LT9C 2J64A 4EPUA 1JC9A 2J3FA 4M7HA 2J61A 1N73C 2XNXC 1LTJC 2HPCB 2GY7A 1LWUC 2OYIC 1RE3B 1FZBC 1FZEC 1M1JB 2HODB 1FZAC 3E1IC 2HLOC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WNP F;  2Z4E B;  1FZG C;  2J61 B;  1N86 C;  1FZC B;  1RE4 B;  2OYH C;  2FFD B;  2Q9I C;  2JHM F;  3H32 C;  3BVH C;  2H43 C;  3GHG C;  2J3O A;  2J0G A;  1LWU B;  1FZB B;  1FZE B;  2J1G A;  4JZC A;  2J3G A;  3E1I B;  2HLO B;  2FIB A;  2J3F D;  1RF1 B;  4R9J A;  2OYH B;  1FZF B;  1LT9 B;  1RF0 C;  4M7F A;  1M1J C;  1FIB A;  2HOD C;  2J3U A;  1N73 B;  2XNX B;  1LTJ B;  2J60 A;  3HUS C;  2OYI B;  2JHL F;  1RE4 C;  4R9T A;  1FZA B;  2J0Y A;  2J2P A;  1FZG B;  4JYO X;  1Z3U A;  1N86 B;  2JHK F;  2HPC C;  2JHI F;  4NYT A;  2Q9I B;  1RE3 C;  1FID A;  1RF0 B;  3H32 B;  2J5Z A;  3BVH B;  2H43 B;  2J0H A;  2Z4E C;  2D39 A;  1FZC C;  1FIC A;  3HUS B;  1RF1 C;  2FFD C;  4ZFG A;  3FIB A;  1FZD A;  1Z3S A;  2JHH C;  1FZF C;  1LT9 C;  2J64 A;  4EPU A;  1JC9 A;  2J3F A;  4M7H A;  2J61 A;  1N73 C;  2XNX C;  1LTJ C;  2HPC B;  2GY7 A;  1LWU C;  2OYI C;  1RE3 B;  1FZB C;  1FZE C;  1M1J B;  2HOD B;  1FZA C;  3E1I C;  2HLO C; 
#chains in the Genus database with same CATH topology
 2WNP F;  2Z4E B;  1FZG C;  2J61 B;  1N86 C;  1FZC B;  1RE4 B;  2OYH C;  2FFD B;  2Q9I C;  2JHM F;  3H32 C;  3BVH C;  2H43 C;  3GHG C;  2J3O A;  2J0G A;  1LWU B;  1FZB B;  1FZE B;  2J1G A;  4JZC A;  2J3G A;  3E1I B;  2HLO B;  2FIB A;  2J3F D;  1RF1 B;  4R9J A;  2OYH B;  1FZF B;  1LT9 B;  1RF0 C;  4M7F A;  1M1J C;  1FIB A;  2HOD C;  2J3U A;  1N73 B;  2XNX B;  1LTJ B;  2J60 A;  3HUS C;  2OYI B;  2JHL F;  1RE4 C;  4R9T A;  1FZA B;  2J0Y A;  2J2P A;  1FZG B;  4JYO X;  1Z3U A;  1N86 B;  2JHK F;  2HPC C;  2JHI F;  4NYT A;  2Q9I B;  1RE3 C;  1FID A;  1RF0 B;  3H32 B;  2J5Z A;  3BVH B;  2H43 B;  3GHG B;  2J0H A;  2Z4E C;  2D39 A;  1FZC C;  1FIC A;  3HUS B;  1RF1 C;  2FFD C;  4ZFG A;  3FIB A;  1FZD A;  1Z3S A;  2JHH C;  1FZF C;  1LT9 C;  2J64 A;  4EPU A;  1JC9 A;  2J3F A;  4M7H A;  2J61 A;  1N73 C;  2XNX C;  1LTJ C;  2HPC B;  2GY7 A;  1LWU C;  2OYI C;  1RE3 B;  1FZB C;  1FZE C;  1M1J B;  2HOD B;  1FZA C;  3E1I C;  2HLO C; 
#chains in the Genus database with same CATH homology
 2WNP F;  2Z4E B;  1FZG C;  2J61 B;  1N86 C;  1FZC B;  1RE4 B;  2OYH C;  2FFD B;  2Q9I C;  2JHM F;  3H32 C;  3BVH C;  2H43 C;  3GHG C;  2J3O A;  2J0G A;  1LWU B;  1FZB B;  1FZE B;  2J1G A;  4JZC A;  2J3G A;  3E1I B;  2HLO B;  2FIB A;  2J3F D;  1RF1 B;  4R9J A;  2OYH B;  1FZF B;  1LT9 B;  1RF0 C;  4M7F A;  1M1J C;  1FIB A;  2HOD C;  2J3U A;  1N73 B;  2XNX B;  1LTJ B;  2J60 A;  3HUS C;  2OYI B;  2JHL F;  1RE4 C;  4R9T A;  1FZA B;  2J0Y A;  2J2P A;  1FZG B;  4JYO X;  1Z3U A;  1N86 B;  2JHK F;  2HPC C;  2JHI F;  4NYT A;  2Q9I B;  1RE3 C;  1FID A;  1RF0 B;  3H32 B;  2J5Z A;  3BVH B;  2H43 B;  2J0H A;  2Z4E C;  2D39 A;  1FZC C;  1FIC A;  3HUS B;  1RF1 C;  2FFD C;  4ZFG A;  3FIB A;  1FZD A;  1Z3S A;  2JHH C;  1FZF C;  1LT9 C;  2J64 A;  4EPU A;  1JC9 A;  2J3F A;  4M7H A;  2J61 A;  1N73 C;  2XNX C;  1LTJ C;  2HPC B;  2GY7 A;  1LWU C;  2OYI C;  1RE3 B;  1FZB C;  1FZE C;  1M1J B;  2HOD B;  1FZA C;  3E1I C;  2HLO C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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