2Z4EB

Crystal structure of d-dimer from human fibrin complexed with gly-his-arg-pro-tyr-amide
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule keywords Fibrinogen alpha chain
total genus 94
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 2007-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2z4eB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2z4eB02
4M7HA 2Z4EB 2HODB 1N86C 1FZBB 4ZFGA 2FIBA 1FZAC 2H43C 2FFDC 3BVHB 2J64A 2XNXB 1FZDA 2J0GA 2J3GA 2J61B 1FZFC 2HLOB 4R9TA 1LT9B 2JHLF 1FZCB 2J1GA 1M1JC 1LTJC 2JHHC 2OYIB 2JHMF 2OYHB 2J2PA 3FIBA 4EPUA 4NYTA 1RE3B 1RF1C 1LWUC 1N73C 1FZCC 2J5ZA 2Q9IB 3HUSB 3E1IC 1FZGB 2J0YA 2GY7A 1RE4C 2J60A 2Z4EC 2HPCB 2HODC 3H32B 1Z3SA 1FZBC 1RE3C 2J3UA 3BVHC 2XNXC 2J3OA 2J3FD 1FZEB 2J61A 1RF0B 2WNPF 4M7FA 4JZCA 2HLOC 1LT9C 1N86B 4JYOX 1FZAB 2FFDB 2OYIC 2OYHC 2JHIF 1FZFB 3GHGC 2J3FA 1M1JB 2Q9IC 1LTJB 3HUSC 1FZGC 1Z3UA 2J0HA 1FIBA 1JC9A 2HPCC 2D39A 3H32C 1RF1B 1LWUB 2H43B 4R9JA 1FIDA 1FZEC 1N73B 1RF0C 1FICA 3E1IB 2JHKF 1RE4B
chains in the Genus database with same CATH superfamily
4M7HA 2Z4EB 2HODB 1N86C 1FZBB 4ZFGA 2FIBA 1FZAC 2H43C 2FFDC 3BVHB 2J64A 2XNXB 1FZDA 2J0GA 2J3GA 2J61B 1FZFC 2HLOB 4R9TA 1LT9B 2JHLF 1FZCB 2J1GA 1M1JC 1LTJC 2JHHC 2OYIB 2JHMF 2OYHB 2J2PA 3FIBA 4EPUA 4NYTA 1RE3B 1RF1C 1LWUC 1N73C 1FZCC 2J5ZA 2Q9IB 3HUSB 3E1IC 1FZGB 2J0YA 2GY7A 1RE4C 2J60A 2Z4EC 2HPCB 2HODC 3H32B 1Z3SA 1FZBC 1RE3C 2J3UA 3BVHC 2XNXC 2J3OA 2J3FD 1FZEB 2J61A 1RF0B 2WNPF 4M7FA 4JZCA 3GHGB 2HLOC 1LT9C 1N86B 4JYOX 1FZAB 2FFDB 2OYIC 2OYHC 2JHIF 1FZFB 3GHGC 2J3FA 1M1JB 2Q9IC 1LTJB 3HUSC 1FZGC 1Z3UA 2J0HA 1FIBA 1JC9A 2HPCC 2D39A 3H32C 1RF1B 1LWUB 2H43B 4R9JA 1FIDA 1FZEC 1N73B 1RF0C 1FICA 3E1IB 2JHKF 1RE4B
chains in the Genus database with same CATH topology
4M7HA 2Z4EB 2HODB 1N86C 1FZBB 4ZFGA 2FIBA 1FZAC 2H43C 2FFDC 3BVHB 2J64A 2XNXB 1FZDA 2J0GA 2J3GA 2J61B 1FZFC 2HLOB 4R9TA 1LT9B 2JHLF 1FZCB 2J1GA 1M1JC 1LTJC 2JHHC 2OYIB 2JHMF 2OYHB 2J2PA 3FIBA 4EPUA 4NYTA 1RE3B 1RF1C 1LWUC 1N73C 1FZCC 2J5ZA 2Q9IB 3HUSB 3E1IC 1FZGB 2J0YA 2GY7A 1RE4C 2J60A 2Z4EC 2HPCB 2HODC 3H32B 1Z3SA 1FZBC 1RE3C 2J3UA 3BVHC 2XNXC 2J3OA 2J3FD 1FZEB 2J61A 1RF0B 2WNPF 4M7FA 4JZCA 2HLOC 1LT9C 1N86B 4JYOX 1FZAB 2FFDB 2OYIC 2OYHC 2JHIF 1FZFB 3GHGC 2J3FA 1M1JB 2Q9IC 1LTJB 3HUSC 1FZGC 1Z3UA 2J0HA 1FIBA 1JC9A 2HPCC 2D39A 3H32C 1RF1B 1LWUB 2H43B 4R9JA 1FIDA 1FZEC 1N73B 1RF0C 1FICA 3E1IB 2JHKF 1RE4B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4M7H A;  2Z4E B;  2HOD B;  1N86 C;  1FZB B;  4ZFG A;  2FIB A;  1FZA C;  2H43 C;  2FFD C;  3BVH B;  2J64 A;  2XNX B;  1FZD A;  2J0G A;  2J3G A;  2J61 B;  1FZF C;  2HLO B;  4R9T A;  1LT9 B;  2JHL F;  1FZC B;  2J1G A;  1M1J C;  1LTJ C;  2JHH C;  2OYI B;  2JHM F;  2OYH B;  2J2P A;  3FIB A;  4EPU A;  4NYT A;  1RE3 B;  1RF1 C;  1LWU C;  1N73 C;  1FZC C;  2J5Z A;  2Q9I B;  3HUS B;  3E1I C;  1FZG B;  2J0Y A;  2GY7 A;  1RE4 C;  2J60 A;  2Z4E C;  2HPC B;  2HOD C;  3H32 B;  1Z3S A;  1FZB C;  1RE3 C;  2J3U A;  3BVH C;  2XNX C;  2J3O A;  2J3F D;  1FZE B;  2J61 A;  1RF0 B;  2WNP F;  4M7F A;  4JZC A;  2HLO C;  1LT9 C;  1N86 B;  4JYO X;  1FZA B;  2FFD B;  2OYI C;  2OYH C;  2JHI F;  1FZF B;  3GHG C;  2J3F A;  1M1J B;  2Q9I C;  1LTJ B;  3HUS C;  1FZG C;  1Z3U A;  2J0H A;  1FIB A;  1JC9 A;  2HPC C;  2D39 A;  3H32 C;  1RF1 B;  1LWU B;  2H43 B;  4R9J A;  1FID A;  1FZE C;  1N73 B;  1RF0 C;  1FIC A;  3E1I B;  2JHK F;  1RE4 B; 
#chains in the Genus database with same CATH topology
 4M7H A;  2Z4E B;  2HOD B;  1N86 C;  1FZB B;  4ZFG A;  2FIB A;  1FZA C;  2H43 C;  2FFD C;  3BVH B;  2J64 A;  2XNX B;  1FZD A;  2J0G A;  2J3G A;  2J61 B;  1FZF C;  2HLO B;  4R9T A;  1LT9 B;  2JHL F;  1FZC B;  2J1G A;  1M1J C;  1LTJ C;  2JHH C;  2OYI B;  2JHM F;  2OYH B;  2J2P A;  3FIB A;  4EPU A;  4NYT A;  1RE3 B;  1RF1 C;  1LWU C;  1N73 C;  1FZC C;  2J5Z A;  2Q9I B;  3HUS B;  3E1I C;  1FZG B;  2J0Y A;  2GY7 A;  1RE4 C;  2J60 A;  2Z4E C;  2HPC B;  2HOD C;  3H32 B;  1Z3S A;  1FZB C;  1RE3 C;  2J3U A;  3BVH C;  2XNX C;  2J3O A;  2J3F D;  1FZE B;  2J61 A;  1RF0 B;  2WNP F;  4M7F A;  4JZC A;  3GHG B;  2HLO C;  1LT9 C;  1N86 B;  4JYO X;  1FZA B;  2FFD B;  2OYI C;  2OYH C;  2JHI F;  1FZF B;  3GHG C;  2J3F A;  1M1J B;  2Q9I C;  1LTJ B;  3HUS C;  1FZG C;  1Z3U A;  2J0H A;  1FIB A;  1JC9 A;  2HPC C;  2D39 A;  3H32 C;  1RF1 B;  1LWU B;  2H43 B;  4R9J A;  1FID A;  1FZE C;  1N73 B;  1RF0 C;  1FIC A;  3E1I B;  2JHK F;  1RE4 B; 
#chains in the Genus database with same CATH homology
 4M7H A;  2Z4E B;  2HOD B;  1N86 C;  1FZB B;  4ZFG A;  2FIB A;  1FZA C;  2H43 C;  2FFD C;  3BVH B;  2J64 A;  2XNX B;  1FZD A;  2J0G A;  2J3G A;  2J61 B;  1FZF C;  2HLO B;  4R9T A;  1LT9 B;  2JHL F;  1FZC B;  2J1G A;  1M1J C;  1LTJ C;  2JHH C;  2OYI B;  2JHM F;  2OYH B;  2J2P A;  3FIB A;  4EPU A;  4NYT A;  1RE3 B;  1RF1 C;  1LWU C;  1N73 C;  1FZC C;  2J5Z A;  2Q9I B;  3HUS B;  3E1I C;  1FZG B;  2J0Y A;  2GY7 A;  1RE4 C;  2J60 A;  2Z4E C;  2HPC B;  2HOD C;  3H32 B;  1Z3S A;  1FZB C;  1RE3 C;  2J3U A;  3BVH C;  2XNX C;  2J3O A;  2J3F D;  1FZE B;  2J61 A;  1RF0 B;  2WNP F;  4M7F A;  4JZC A;  2HLO C;  1LT9 C;  1N86 B;  4JYO X;  1FZA B;  2FFD B;  2OYI C;  2OYH C;  2JHI F;  1FZF B;  3GHG C;  2J3F A;  1M1J B;  2Q9I C;  1LTJ B;  3HUS C;  1FZG C;  1Z3U A;  2J0H A;  1FIB A;  1JC9 A;  2HPC C;  2D39 A;  3H32 C;  1RF1 B;  1LWU B;  2H43 B;  4R9J A;  1FID A;  1FZE C;  1N73 B;  1RF0 C;  1FIC A;  3E1I B;  2JHK F;  1RE4 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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