2FIBA

Recombinant human gamma-fibrinogen carboxyl terminal fragment (residues 143-411) complexed to the peptide gly-pro-arg-pro at ph 6.0
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
250
structure length
250
Chain Sequence
VQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
pubmed doi rcsb
molecule tags Complex (blood coagulation/peptide)
source organism Homo sapiens
molecule keywords FIBRINOGEN
total genus 73
structure length 250
sequence length 250
ec nomenclature
pdb deposition date 1997-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2fibA01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2fibA02
3FIBA 1FZCC 2J0GA 2FFDC 1RF0C 1FZAC 1RE3B 1LT9C 2H43C 1N73C 3E1IC 3HUSC 2JHMF 2J3FD 4M7HA 2OYIC 1RE4C 2JHIF 4R9TA 1FZEC 1N86C 2HLOC 1FZGB 1FZFB 4JYOX 2Q9IB 2JHHC 1M1JB 1LWUC 2D39A 1FZCB 2HODC 2FFDB 3GHGC 2GY7A 1RF1C 4NYTA 1FZAB 4JZCA 2WNPF 2XNXC 1LT9B 2H43B 1N73B 3E1IB 3HUSB 2JHKF 1FZBC 2OYIB 1LTJC 1RE4B 1FICA 1FIBA 2J61B 3H32B 2HPCB 2Z4EC 1JC9A 2J60A 2J3FA 1LWUB 4ZFGA 2J3GA 2HODB 1RE3C 1RF0B 2J3UA 2J0YA 1RF1B 2J1GA 2J0HA 1Z3SA 2J5ZA 2XNXB 2OYHC 1FZDA 3BVHC 1FZBB 1LTJB 1FZEB 1N86B 2J64A 2Z4EB 2HLOB 4M7FA 4R9JA 2J2PA 2J3OA 1Z3UA 4EPUA 2FIBA 2JHLF 3H32C 2HPCC 2J61A 1FZGC 1FZFC 2OYHB 1FIDA 2Q9IC 3BVHB 1M1JC
chains in the Genus database with same CATH superfamily
3FIBA 1FZCC 2J0GA 2FFDC 1RF0C 1FZAC 1RE3B 1LT9C 2H43C 1N73C 3E1IC 3HUSC 2JHMF 2J3FD 4M7HA 2OYIC 1RE4C 2JHIF 4R9TA 1FZEC 1N86C 2HLOC 1FZGB 1FZFB 4JYOX 2Q9IB 2JHHC 1M1JB 1LWUC 2D39A 1FZCB 2HODC 2FFDB 3GHGC 2GY7A 1RF1C 4NYTA 1FZAB 4JZCA 2WNPF 2XNXC 1LT9B 2H43B 1N73B 3E1IB 3HUSB 2JHKF 1FZBC 2OYIB 1LTJC 1RE4B 1FICA 1FIBA 2J61B 3H32B 2HPCB 2Z4EC 1JC9A 2J60A 2J3FA 1LWUB 4ZFGA 2J3GA 2HODB 3GHGB 1RE3C 1RF0B 2J3UA 2J0YA 1RF1B 2J1GA 2J0HA 1Z3SA 2J5ZA 2XNXB 2OYHC 1FZDA 3BVHC 1FZBB 1LTJB 1FZEB 1N86B 2J64A 2Z4EB 2HLOB 4M7FA 4R9JA 2J2PA 2J3OA 1Z3UA 4EPUA 2FIBA 2JHLF 3H32C 2HPCC 2J61A 1FZGC 1FZFC 2OYHB 1FIDA 2Q9IC 3BVHB 1M1JC
chains in the Genus database with same CATH topology
3FIBA 1FZCC 2J0GA 2FFDC 1RF0C 1FZAC 1RE3B 1LT9C 2H43C 1N73C 3E1IC 3HUSC 2JHMF 2J3FD 4M7HA 2OYIC 1RE4C 2JHIF 4R9TA 1FZEC 1N86C 2HLOC 1FZGB 1FZFB 4JYOX 2Q9IB 2JHHC 1M1JB 1LWUC 2D39A 1FZCB 2HODC 2FFDB 3GHGC 2GY7A 1RF1C 4NYTA 1FZAB 4JZCA 2WNPF 2XNXC 1LT9B 2H43B 1N73B 3E1IB 3HUSB 2JHKF 1FZBC 2OYIB 1LTJC 1RE4B 1FICA 1FIBA 2J61B 3H32B 2HPCB 2Z4EC 1JC9A 2J60A 2J3FA 1LWUB 4ZFGA 2J3GA 2HODB 1RE3C 1RF0B 2J3UA 2J0YA 1RF1B 2J1GA 2J0HA 1Z3SA 2J5ZA 2XNXB 2OYHC 1FZDA 3BVHC 1FZBB 1LTJB 1FZEB 1N86B 2J64A 2Z4EB 2HLOB 4M7FA 4R9JA 2J2PA 2J3OA 1Z3UA 4EPUA 2FIBA 2JHLF 3H32C 2HPCC 2J61A 1FZGC 1FZFC 2OYHB 1FIDA 2Q9IC 3BVHB 1M1JC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FIB A;  1FZC C;  2J0G A;  2FFD C;  1RF0 C;  1FZA C;  1RE3 B;  1LT9 C;  2H43 C;  1N73 C;  3E1I C;  3HUS C;  2JHM F;  2J3F D;  4M7H A;  2OYI C;  1RE4 C;  2JHI F;  4R9T A;  1FZE C;  1N86 C;  2HLO C;  1FZG B;  1FZF B;  4JYO X;  2Q9I B;  2JHH C;  1M1J B;  1LWU C;  2D39 A;  1FZC B;  2HOD C;  2FFD B;  3GHG C;  2GY7 A;  1RF1 C;  4NYT A;  1FZA B;  4JZC A;  2WNP F;  2XNX C;  1LT9 B;  2H43 B;  1N73 B;  3E1I B;  3HUS B;  2JHK F;  1FZB C;  2OYI B;  1LTJ C;  1RE4 B;  1FIC A;  1FIB A;  2J61 B;  3H32 B;  2HPC B;  2Z4E C;  1JC9 A;  2J60 A;  2J3F A;  1LWU B;  4ZFG A;  2J3G A;  2HOD B;  1RE3 C;  1RF0 B;  2J3U A;  2J0Y A;  1RF1 B;  2J1G A;  2J0H A;  1Z3S A;  2J5Z A;  2XNX B;  2OYH C;  1FZD A;  3BVH C;  1FZB B;  1LTJ B;  1FZE B;  1N86 B;  2J64 A;  2Z4E B;  2HLO B;  4M7F A;  4R9J A;  2J2P A;  2J3O A;  1Z3U A;  4EPU A;  2FIB A;  2JHL F;  3H32 C;  2HPC C;  2J61 A;  1FZG C;  1FZF C;  2OYH B;  1FID A;  2Q9I C;  3BVH B;  1M1J C; 
#chains in the Genus database with same CATH topology
 3FIB A;  1FZC C;  2J0G A;  2FFD C;  1RF0 C;  1FZA C;  1RE3 B;  1LT9 C;  2H43 C;  1N73 C;  3E1I C;  3HUS C;  2JHM F;  2J3F D;  4M7H A;  2OYI C;  1RE4 C;  2JHI F;  4R9T A;  1FZE C;  1N86 C;  2HLO C;  1FZG B;  1FZF B;  4JYO X;  2Q9I B;  2JHH C;  1M1J B;  1LWU C;  2D39 A;  1FZC B;  2HOD C;  2FFD B;  3GHG C;  2GY7 A;  1RF1 C;  4NYT A;  1FZA B;  4JZC A;  2WNP F;  2XNX C;  1LT9 B;  2H43 B;  1N73 B;  3E1I B;  3HUS B;  2JHK F;  1FZB C;  2OYI B;  1LTJ C;  1RE4 B;  1FIC A;  1FIB A;  2J61 B;  3H32 B;  2HPC B;  2Z4E C;  1JC9 A;  2J60 A;  2J3F A;  1LWU B;  4ZFG A;  2J3G A;  2HOD B;  3GHG B;  1RE3 C;  1RF0 B;  2J3U A;  2J0Y A;  1RF1 B;  2J1G A;  2J0H A;  1Z3S A;  2J5Z A;  2XNX B;  2OYH C;  1FZD A;  3BVH C;  1FZB B;  1LTJ B;  1FZE B;  1N86 B;  2J64 A;  2Z4E B;  2HLO B;  4M7F A;  4R9J A;  2J2P A;  2J3O A;  1Z3U A;  4EPU A;  2FIB A;  2JHL F;  3H32 C;  2HPC C;  2J61 A;  1FZG C;  1FZF C;  2OYH B;  1FID A;  2Q9I C;  3BVH B;  1M1J C; 
#chains in the Genus database with same CATH homology
 3FIB A;  1FZC C;  2J0G A;  2FFD C;  1RF0 C;  1FZA C;  1RE3 B;  1LT9 C;  2H43 C;  1N73 C;  3E1I C;  3HUS C;  2JHM F;  2J3F D;  4M7H A;  2OYI C;  1RE4 C;  2JHI F;  4R9T A;  1FZE C;  1N86 C;  2HLO C;  1FZG B;  1FZF B;  4JYO X;  2Q9I B;  2JHH C;  1M1J B;  1LWU C;  2D39 A;  1FZC B;  2HOD C;  2FFD B;  3GHG C;  2GY7 A;  1RF1 C;  4NYT A;  1FZA B;  4JZC A;  2WNP F;  2XNX C;  1LT9 B;  2H43 B;  1N73 B;  3E1I B;  3HUS B;  2JHK F;  1FZB C;  2OYI B;  1LTJ C;  1RE4 B;  1FIC A;  1FIB A;  2J61 B;  3H32 B;  2HPC B;  2Z4E C;  1JC9 A;  2J60 A;  2J3F A;  1LWU B;  4ZFG A;  2J3G A;  2HOD B;  1RE3 C;  1RF0 B;  2J3U A;  2J0Y A;  1RF1 B;  2J1G A;  2J0H A;  1Z3S A;  2J5Z A;  2XNX B;  2OYH C;  1FZD A;  3BVH C;  1FZB B;  1LTJ B;  1FZE B;  1N86 B;  2J64 A;  2Z4E B;  2HLO B;  4M7F A;  4R9J A;  2J2P A;  2J3O A;  1Z3U A;  4EPU A;  2FIB A;  2JHL F;  3H32 C;  2HPC C;  2J61 A;  1FZG C;  1FZF C;  2OYH B;  1FID A;  2Q9I C;  3BVH B;  1M1J C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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