2HPCC

Crystal structure of fragment d from human fibrinogen complexed with gly-pro-arg-pro-amide.
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
305
structure length
305
Chain Sequence
EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 51
structure length 305
sequence length 305
chains with identical sequence F, I, L
ec nomenclature
pdb deposition date 2006-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2hpcC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2hpcC02
3HUSC 2FFDC 4ZFGA 1FZEB 1N86B 1RE3C 2OYIC 1FZGB 2J61B 1M1JB 2J60A 1RE4C 1RF1C 2Z4EC 2J3UA 4M7FA 1FZDA 2J0HA 1FZBC 1LWUC 1LTJB 3H32B 2J3FA 1RF0B 4R9TA 2Q9IB 2J2PA 2OYHB 2J3FD 2J0GA 4EPUA 3BVHB 4JZCA 3HUSB 2FFDB 2JHMF 2GY7A 1RE3B 2J64A 2OYIB 2JHIF 3E1IC 1RE4B 1RF1B 2Z4EB 1FIDA 1FZBB 1LWUB 1JC9A 1FZCC 3FIBA 1LT9C 2HLOB 4NYTA 2HLOC 1FZFC 1FICA 2H43C 1FZAB 1FZAC 1Z3SA 2HPCC 2JHLF 1N73C 2J3GA 3E1IB 2JHKF 4JYOX 2HODC 1FZCB 2J0YA 1LT9B 2JHHC 2WNPF 2J3OA 2XNXC 1Z3UA 1FZFB 1FIBA 2H43B 2FIBA 2J5ZA 1FZEC 2HPCB 1N86C 3GHGC 1N73B 1FZGC 1M1JC 2J61A 4M7HA 2HODB 1LTJC 3H32C 1RF0C 2XNXB 2Q9IC 2OYHC 2J1GA 4R9JA 3BVHC 2D39A
chains in the Genus database with same CATH superfamily
3HUSC 2FFDC 4ZFGA 1FZEB 1N86B 3GHGB 1RE3C 2OYIC 1FZGB 2J61B 1M1JB 2J60A 1RE4C 1RF1C 2Z4EC 2J3UA 4M7FA 1FZDA 2J0HA 1FZBC 1LWUC 1LTJB 3H32B 2J3FA 1RF0B 4R9TA 2Q9IB 2J2PA 2OYHB 2J3FD 2J0GA 4EPUA 3BVHB 4JZCA 3HUSB 2FFDB 2JHMF 2GY7A 1RE3B 2J64A 2OYIB 2JHIF 3E1IC 1RE4B 1RF1B 2Z4EB 1FIDA 1FZBB 1LWUB 1JC9A 1FZCC 3FIBA 1LT9C 2HLOB 4NYTA 2HLOC 1FZFC 1FICA 2H43C 1FZAB 1FZAC 1Z3SA 2HPCC 2JHLF 1N73C 2J3GA 3E1IB 2JHKF 4JYOX 2HODC 1FZCB 2J0YA 1LT9B 2JHHC 2WNPF 2J3OA 2XNXC 1Z3UA 1FZFB 1FIBA 2H43B 2FIBA 2J5ZA 1FZEC 2HPCB 1N86C 3GHGC 1N73B 1FZGC 1M1JC 2J61A 4M7HA 2HODB 1LTJC 3H32C 1RF0C 2XNXB 2Q9IC 2OYHC 2J1GA 4R9JA 3BVHC 2D39A
chains in the Genus database with same CATH topology
3HUSC 2FFDC 4ZFGA 1FZEB 1N86B 1RE3C 2OYIC 1FZGB 2J61B 1M1JB 2J60A 1RE4C 1RF1C 2Z4EC 2J3UA 4M7FA 1FZDA 2J0HA 1FZBC 1LWUC 1LTJB 3H32B 2J3FA 1RF0B 4R9TA 2Q9IB 2J2PA 2OYHB 2J3FD 2J0GA 4EPUA 3BVHB 4JZCA 3HUSB 2FFDB 2JHMF 2GY7A 1RE3B 2J64A 2OYIB 2JHIF 3E1IC 1RE4B 1RF1B 2Z4EB 1FIDA 1FZBB 1LWUB 1JC9A 1FZCC 3FIBA 1LT9C 2HLOB 4NYTA 2HLOC 1FZFC 1FICA 2H43C 1FZAB 1FZAC 1Z3SA 2HPCC 2JHLF 1N73C 2J3GA 3E1IB 2JHKF 4JYOX 2HODC 1FZCB 2J0YA 1LT9B 2JHHC 2WNPF 2J3OA 2XNXC 1Z3UA 1FZFB 1FIBA 2H43B 2FIBA 2J5ZA 1FZEC 2HPCB 1N86C 3GHGC 1N73B 1FZGC 1M1JC 2J61A 4M7HA 2HODB 1LTJC 3H32C 1RF0C 2XNXB 2Q9IC 2OYHC 2J1GA 4R9JA 3BVHC 2D39A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HUS C;  2FFD C;  4ZFG A;  1FZE B;  1N86 B;  1RE3 C;  2OYI C;  1FZG B;  2J61 B;  1M1J B;  2J60 A;  1RE4 C;  1RF1 C;  2Z4E C;  2J3U A;  4M7F A;  1FZD A;  2J0H A;  1FZB C;  1LWU C;  1LTJ B;  3H32 B;  2J3F A;  1RF0 B;  4R9T A;  2Q9I B;  2J2P A;  2OYH B;  2J3F D;  2J0G A;  4EPU A;  3BVH B;  4JZC A;  3HUS B;  2FFD B;  2JHM F;  2GY7 A;  1RE3 B;  2J64 A;  2OYI B;  2JHI F;  3E1I C;  1RE4 B;  1RF1 B;  2Z4E B;  1FID A;  1FZB B;  1LWU B;  1JC9 A;  1FZC C;  3FIB A;  1LT9 C;  2HLO B;  4NYT A;  2HLO C;  1FZF C;  1FIC A;  2H43 C;  1FZA B;  1FZA C;  1Z3S A;  2HPC C;  2JHL F;  1N73 C;  2J3G A;  3E1I B;  2JHK F;  4JYO X;  2HOD C;  1FZC B;  2J0Y A;  1LT9 B;  2JHH C;  2WNP F;  2J3O A;  2XNX C;  1Z3U A;  1FZF B;  1FIB A;  2H43 B;  2FIB A;  2J5Z A;  1FZE C;  2HPC B;  1N86 C;  3GHG C;  1N73 B;  1FZG C;  1M1J C;  2J61 A;  4M7H A;  2HOD B;  1LTJ C;  3H32 C;  1RF0 C;  2XNX B;  2Q9I C;  2OYH C;  2J1G A;  4R9J A;  3BVH C;  2D39 A; 
#chains in the Genus database with same CATH topology
 3HUS C;  2FFD C;  4ZFG A;  1FZE B;  1N86 B;  3GHG B;  1RE3 C;  2OYI C;  1FZG B;  2J61 B;  1M1J B;  2J60 A;  1RE4 C;  1RF1 C;  2Z4E C;  2J3U A;  4M7F A;  1FZD A;  2J0H A;  1FZB C;  1LWU C;  1LTJ B;  3H32 B;  2J3F A;  1RF0 B;  4R9T A;  2Q9I B;  2J2P A;  2OYH B;  2J3F D;  2J0G A;  4EPU A;  3BVH B;  4JZC A;  3HUS B;  2FFD B;  2JHM F;  2GY7 A;  1RE3 B;  2J64 A;  2OYI B;  2JHI F;  3E1I C;  1RE4 B;  1RF1 B;  2Z4E B;  1FID A;  1FZB B;  1LWU B;  1JC9 A;  1FZC C;  3FIB A;  1LT9 C;  2HLO B;  4NYT A;  2HLO C;  1FZF C;  1FIC A;  2H43 C;  1FZA B;  1FZA C;  1Z3S A;  2HPC C;  2JHL F;  1N73 C;  2J3G A;  3E1I B;  2JHK F;  4JYO X;  2HOD C;  1FZC B;  2J0Y A;  1LT9 B;  2JHH C;  2WNP F;  2J3O A;  2XNX C;  1Z3U A;  1FZF B;  1FIB A;  2H43 B;  2FIB A;  2J5Z A;  1FZE C;  2HPC B;  1N86 C;  3GHG C;  1N73 B;  1FZG C;  1M1J C;  2J61 A;  4M7H A;  2HOD B;  1LTJ C;  3H32 C;  1RF0 C;  2XNX B;  2Q9I C;  2OYH C;  2J1G A;  4R9J A;  3BVH C;  2D39 A; 
#chains in the Genus database with same CATH homology
 3HUS C;  2FFD C;  4ZFG A;  1FZE B;  1N86 B;  1RE3 C;  2OYI C;  1FZG B;  2J61 B;  1M1J B;  2J60 A;  1RE4 C;  1RF1 C;  2Z4E C;  2J3U A;  4M7F A;  1FZD A;  2J0H A;  1FZB C;  1LWU C;  1LTJ B;  3H32 B;  2J3F A;  1RF0 B;  4R9T A;  2Q9I B;  2J2P A;  2OYH B;  2J3F D;  2J0G A;  4EPU A;  3BVH B;  4JZC A;  3HUS B;  2FFD B;  2JHM F;  2GY7 A;  1RE3 B;  2J64 A;  2OYI B;  2JHI F;  3E1I C;  1RE4 B;  1RF1 B;  2Z4E B;  1FID A;  1FZB B;  1LWU B;  1JC9 A;  1FZC C;  3FIB A;  1LT9 C;  2HLO B;  4NYT A;  2HLO C;  1FZF C;  1FIC A;  2H43 C;  1FZA B;  1FZA C;  1Z3S A;  2HPC C;  2JHL F;  1N73 C;  2J3G A;  3E1I B;  2JHK F;  4JYO X;  2HOD C;  1FZC B;  2J0Y A;  1LT9 B;  2JHH C;  2WNP F;  2J3O A;  2XNX C;  1Z3U A;  1FZF B;  1FIB A;  2H43 B;  2FIB A;  2J5Z A;  1FZE C;  2HPC B;  1N86 C;  3GHG C;  1N73 B;  1FZG C;  1M1J C;  2J61 A;  4M7H A;  2HOD B;  1LTJ C;  3H32 C;  1RF0 C;  2XNX B;  2Q9I C;  2OYH C;  2J1G A;  4R9J A;  3BVH C;  2D39 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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