2J2PA

L-ficolin complexed to n-acetyl-cystein (150mm)
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
214
structure length
214
Chain Sequence
TGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRTDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHTSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
pubmed doi rcsb
molecule tags Lectin
source organism Homo sapiens
molecule keywords FICOLIN-2
total genus 65
structure length 214
sequence length 214
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2006-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2j2pA01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2j2pA02
1FZEC 2HLOB 1FZBC 1RE4C 2XNXB 2J3FA 3HUSB 2JHMF 3GHGC 2OYIB 2J0GA 1FZCC 2J3OA 1FZFC 1N73B 2H43C 2GY7A 2OYHC 2J0YA 1N86C 1Z3SA 2J3UA 4R9TA 1Z3UA 3E1IC 1M1JC 1RF1B 2J1GA 1LT9B 1FZAC 2HODC 1RE3C 3H32B 4JZCA 3BVHC 2JHLF 2HPCC 1FZGC 2FFDB 1LWUC 1FZBB 2J3FD 1FIBA 2J2PA 1FICA 2J0HA 4NYTA 2HLOC 4R9JA 2H43B 1RF0B 2Z4EB 2Q9IB 1FIDA 2JHKF 1N73C 1FZAB 1FZEB 2FIBA 2J5ZA 2J3GA 2J61A 1RE4B 1FZDA 1LTJC 1LT9C 1LWUB 1JC9A 2JHHC 1FZCB 2J60A 3H32C 1FZFB 4M7FA 2XNXC 2OYHB 2WNPF 3HUSC 4ZFGA 4JYOX 2FFDC 1N86B 2OYIC 2D39A 3E1IB 1M1JB 2HODB 1RE3B 3FIBA 2J64A 1RF0C 4M7HA 3BVHB 2Z4EC 2HPCB 1FZGB 4EPUA 1RF1C 2Q9IC 2J61B 2JHIF 1LTJB
chains in the Genus database with same CATH superfamily
1FZEC 2HLOB 1FZBC 1RE4C 2XNXB 2J3FA 3HUSB 2JHMF 3GHGC 2OYIB 2J0GA 1FZCC 2J3OA 1FZFC 1N73B 2H43C 2GY7A 2OYHC 2J0YA 1N86C 1Z3SA 2J3UA 4R9TA 1Z3UA 3E1IC 1M1JC 1RF1B 2J1GA 1LT9B 1FZAC 2HODC 1RE3C 3H32B 4JZCA 3BVHC 2JHLF 2HPCC 1FZGC 2FFDB 1LWUC 1FZBB 2J3FD 1FIBA 2J2PA 1FICA 2J0HA 4NYTA 2HLOC 4R9JA 2H43B 1RF0B 2Z4EB 2Q9IB 1FIDA 2JHKF 1N73C 1FZAB 1FZEB 2FIBA 2J5ZA 2J3GA 2J61A 1RE4B 1FZDA 1LTJC 3GHGB 1LT9C 1LWUB 1JC9A 2JHHC 1FZCB 2J60A 3H32C 1FZFB 4M7FA 2XNXC 2OYHB 2WNPF 3HUSC 4ZFGA 4JYOX 2FFDC 1N86B 2OYIC 2D39A 3E1IB 1M1JB 2HODB 1RE3B 3FIBA 2J64A 1RF0C 4M7HA 3BVHB 2Z4EC 2HPCB 1FZGB 4EPUA 1RF1C 2Q9IC 2J61B 2JHIF 1LTJB
chains in the Genus database with same CATH topology
1FZEC 2HLOB 1FZBC 1RE4C 2XNXB 2J3FA 3HUSB 2JHMF 3GHGC 2OYIB 2J0GA 1FZCC 2J3OA 1FZFC 1N73B 2H43C 2GY7A 2OYHC 2J0YA 1N86C 1Z3SA 2J3UA 4R9TA 1Z3UA 3E1IC 1M1JC 1RF1B 2J1GA 1LT9B 1FZAC 2HODC 1RE3C 3H32B 4JZCA 3BVHC 2JHLF 2HPCC 1FZGC 2FFDB 1LWUC 1FZBB 2J3FD 1FIBA 2J2PA 1FICA 2J0HA 4NYTA 2HLOC 4R9JA 2H43B 1RF0B 2Z4EB 2Q9IB 1FIDA 2JHKF 1N73C 1FZAB 1FZEB 2FIBA 2J5ZA 2J3GA 2J61A 1RE4B 1FZDA 1LTJC 1LT9C 1LWUB 1JC9A 2JHHC 1FZCB 2J60A 3H32C 1FZFB 4M7FA 2XNXC 2OYHB 2WNPF 3HUSC 4ZFGA 4JYOX 2FFDC 1N86B 2OYIC 2D39A 3E1IB 1M1JB 2HODB 1RE3B 3FIBA 2J64A 1RF0C 4M7HA 3BVHB 2Z4EC 2HPCB 1FZGB 4EPUA 1RF1C 2Q9IC 2J61B 2JHIF 1LTJB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZE C;  2HLO B;  1FZB C;  1RE4 C;  2XNX B;  2J3F A;  3HUS B;  2JHM F;  3GHG C;  2OYI B;  2J0G A;  1FZC C;  2J3O A;  1FZF C;  1N73 B;  2H43 C;  2GY7 A;  2OYH C;  2J0Y A;  1N86 C;  1Z3S A;  2J3U A;  4R9T A;  1Z3U A;  3E1I C;  1M1J C;  1RF1 B;  2J1G A;  1LT9 B;  1FZA C;  2HOD C;  1RE3 C;  3H32 B;  4JZC A;  3BVH C;  2JHL F;  2HPC C;  1FZG C;  2FFD B;  1LWU C;  1FZB B;  2J3F D;  1FIB A;  2J2P A;  1FIC A;  2J0H A;  4NYT A;  2HLO C;  4R9J A;  2H43 B;  1RF0 B;  2Z4E B;  2Q9I B;  1FID A;  2JHK F;  1N73 C;  1FZA B;  1FZE B;  2FIB A;  2J5Z A;  2J3G A;  2J61 A;  1RE4 B;  1FZD A;  1LTJ C;  1LT9 C;  1LWU B;  1JC9 A;  2JHH C;  1FZC B;  2J60 A;  3H32 C;  1FZF B;  4M7F A;  2XNX C;  2OYH B;  2WNP F;  3HUS C;  4ZFG A;  4JYO X;  2FFD C;  1N86 B;  2OYI C;  2D39 A;  3E1I B;  1M1J B;  2HOD B;  1RE3 B;  3FIB A;  2J64 A;  1RF0 C;  4M7H A;  3BVH B;  2Z4E C;  2HPC B;  1FZG B;  4EPU A;  1RF1 C;  2Q9I C;  2J61 B;  2JHI F;  1LTJ B; 
#chains in the Genus database with same CATH topology
 1FZE C;  2HLO B;  1FZB C;  1RE4 C;  2XNX B;  2J3F A;  3HUS B;  2JHM F;  3GHG C;  2OYI B;  2J0G A;  1FZC C;  2J3O A;  1FZF C;  1N73 B;  2H43 C;  2GY7 A;  2OYH C;  2J0Y A;  1N86 C;  1Z3S A;  2J3U A;  4R9T A;  1Z3U A;  3E1I C;  1M1J C;  1RF1 B;  2J1G A;  1LT9 B;  1FZA C;  2HOD C;  1RE3 C;  3H32 B;  4JZC A;  3BVH C;  2JHL F;  2HPC C;  1FZG C;  2FFD B;  1LWU C;  1FZB B;  2J3F D;  1FIB A;  2J2P A;  1FIC A;  2J0H A;  4NYT A;  2HLO C;  4R9J A;  2H43 B;  1RF0 B;  2Z4E B;  2Q9I B;  1FID A;  2JHK F;  1N73 C;  1FZA B;  1FZE B;  2FIB A;  2J5Z A;  2J3G A;  2J61 A;  1RE4 B;  1FZD A;  1LTJ C;  3GHG B;  1LT9 C;  1LWU B;  1JC9 A;  2JHH C;  1FZC B;  2J60 A;  3H32 C;  1FZF B;  4M7F A;  2XNX C;  2OYH B;  2WNP F;  3HUS C;  4ZFG A;  4JYO X;  2FFD C;  1N86 B;  2OYI C;  2D39 A;  3E1I B;  1M1J B;  2HOD B;  1RE3 B;  3FIB A;  2J64 A;  1RF0 C;  4M7H A;  3BVH B;  2Z4E C;  2HPC B;  1FZG B;  4EPU A;  1RF1 C;  2Q9I C;  2J61 B;  2JHI F;  1LTJ B; 
#chains in the Genus database with same CATH homology
 1FZE C;  2HLO B;  1FZB C;  1RE4 C;  2XNX B;  2J3F A;  3HUS B;  2JHM F;  3GHG C;  2OYI B;  2J0G A;  1FZC C;  2J3O A;  1FZF C;  1N73 B;  2H43 C;  2GY7 A;  2OYH C;  2J0Y A;  1N86 C;  1Z3S A;  2J3U A;  4R9T A;  1Z3U A;  3E1I C;  1M1J C;  1RF1 B;  2J1G A;  1LT9 B;  1FZA C;  2HOD C;  1RE3 C;  3H32 B;  4JZC A;  3BVH C;  2JHL F;  2HPC C;  1FZG C;  2FFD B;  1LWU C;  1FZB B;  2J3F D;  1FIB A;  2J2P A;  1FIC A;  2J0H A;  4NYT A;  2HLO C;  4R9J A;  2H43 B;  1RF0 B;  2Z4E B;  2Q9I B;  1FID A;  2JHK F;  1N73 C;  1FZA B;  1FZE B;  2FIB A;  2J5Z A;  2J3G A;  2J61 A;  1RE4 B;  1FZD A;  1LTJ C;  1LT9 C;  1LWU B;  1JC9 A;  2JHH C;  1FZC B;  2J60 A;  3H32 C;  1FZF B;  4M7F A;  2XNX C;  2OYH B;  2WNP F;  3HUS C;  4ZFG A;  4JYO X;  2FFD C;  1N86 B;  2OYI C;  2D39 A;  3E1I B;  1M1J B;  2HOD B;  1RE3 B;  3FIB A;  2J64 A;  1RF0 C;  4M7H A;  3BVH B;  2Z4E C;  2HPC B;  1FZG B;  4EPU A;  1RF1 C;  2Q9I C;  2J61 B;  2JHI F;  1LTJ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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