2JHHC

Structure of globular heads of m-ficolin at acidic ph
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
217
structure length
208
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 59
structure length 208
sequence length 217
chains with identical sequence F
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhhC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhhC02
1FZDA 2J5ZA 2OYIC 2FFDC 2HLOC 3BVHB 4NYTA 2J3FD 1RE4B 2FIBA 2J0GA 3H32C 1LTJB 2J3UA 2JHMF 1RF1C 4M7FA 2HPCB 1LT9C 3E1IC 1M1JB 4JYOX 2JHIF 2WNPF 2XNXC 1FZBB 1FZCB 2OYHC 1FICA 1RE3C 1FZEC 1RF0C 1FZAB 2J61B 1FZFC 1FZGB 4M7HA 3HUSC 4R9TA 2Q9IC 1N86C 3FIBA 2JHLF 2J64A 2FFDB 2J61A 2OYIB 2J60A 2HLOB 2HODC 1N73C 1LWUC 3H32B 2J1GA 2J3OA 2J3FA 2H43C 2Z4EC 1Z3UA 1LT9B 4JZCA 4R9JA 2J0YA 2J3GA 3E1IB 1JC9A 3BVHC 1RE4C 2XNXB 2J0HA 1FIBA 1LTJC 2J2PA 2D39A 2HPCC 2OYHB 1RE3B 1FZEB 3GHGC 1RF0B 1FZFB 3HUSB 1M1JC 2Q9IB 2JHHC 1N86B 1RF1B 4EPUA 2JHKF 1FZBC 2GY7A 1FZCC 2HODB 1N73B 1LWUB 1FIDA 1Z3SA 1FZAC 1FZGC 2H43B 4ZFGA 2Z4EB
chains in the Genus database with same CATH superfamily
1FZDA 2J5ZA 2OYIC 2FFDC 2HLOC 3BVHB 4NYTA 2J3FD 1RE4B 2FIBA 2J0GA 3H32C 1LTJB 2J3UA 2JHMF 1RF1C 4M7FA 2HPCB 1LT9C 3GHGB 3E1IC 1M1JB 4JYOX 2JHIF 2WNPF 2XNXC 1FZBB 1FZCB 2OYHC 1FICA 1RE3C 1FZEC 1RF0C 1FZAB 2J61B 1FZFC 1FZGB 4M7HA 3HUSC 4R9TA 2Q9IC 1N86C 3FIBA 2JHLF 2J64A 2FFDB 2J61A 2OYIB 2J60A 2HLOB 2HODC 1N73C 1LWUC 3H32B 2J1GA 2J3OA 2J3FA 2H43C 2Z4EC 1Z3UA 1LT9B 4JZCA 4R9JA 2J0YA 2J3GA 3E1IB 1JC9A 3BVHC 1RE4C 2XNXB 2J0HA 1FIBA 1LTJC 2J2PA 2D39A 2HPCC 2OYHB 1RE3B 1FZEB 3GHGC 1RF0B 1FZFB 3HUSB 1M1JC 2Q9IB 2JHHC 1N86B 1RF1B 4EPUA 2JHKF 1FZBC 2GY7A 1FZCC 2HODB 1N73B 1LWUB 1FIDA 1Z3SA 1FZAC 1FZGC 2H43B 4ZFGA 2Z4EB
chains in the Genus database with same CATH topology
1FZDA 2J5ZA 2OYIC 2FFDC 2HLOC 3BVHB 4NYTA 2J3FD 1RE4B 2FIBA 2J0GA 3H32C 1LTJB 2J3UA 2JHMF 1RF1C 4M7FA 2HPCB 1LT9C 3E1IC 1M1JB 4JYOX 2JHIF 2WNPF 2XNXC 1FZBB 1FZCB 2OYHC 1FICA 1RE3C 1FZEC 1RF0C 1FZAB 2J61B 1FZFC 1FZGB 4M7HA 3HUSC 4R9TA 2Q9IC 1N86C 3FIBA 2JHLF 2J64A 2FFDB 2J61A 2OYIB 2J60A 2HLOB 2HODC 1N73C 1LWUC 3H32B 2J1GA 2J3OA 2J3FA 2H43C 2Z4EC 1Z3UA 1LT9B 4JZCA 4R9JA 2J0YA 2J3GA 3E1IB 1JC9A 3BVHC 1RE4C 2XNXB 2J0HA 1FIBA 1LTJC 2J2PA 2D39A 2HPCC 2OYHB 1RE3B 1FZEB 3GHGC 1RF0B 1FZFB 3HUSB 1M1JC 2Q9IB 2JHHC 1N86B 1RF1B 4EPUA 2JHKF 1FZBC 2GY7A 1FZCC 2HODB 1N73B 1LWUB 1FIDA 1Z3SA 1FZAC 1FZGC 2H43B 4ZFGA 2Z4EB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZD A;  2J5Z A;  2OYI C;  2FFD C;  2HLO C;  3BVH B;  4NYT A;  2J3F D;  1RE4 B;  2FIB A;  2J0G A;  3H32 C;  1LTJ B;  2J3U A;  2JHM F;  1RF1 C;  4M7F A;  2HPC B;  1LT9 C;  3E1I C;  1M1J B;  4JYO X;  2JHI F;  2WNP F;  2XNX C;  1FZB B;  1FZC B;  2OYH C;  1FIC A;  1RE3 C;  1FZE C;  1RF0 C;  1FZA B;  2J61 B;  1FZF C;  1FZG B;  4M7H A;  3HUS C;  4R9T A;  2Q9I C;  1N86 C;  3FIB A;  2JHL F;  2J64 A;  2FFD B;  2J61 A;  2OYI B;  2J60 A;  2HLO B;  2HOD C;  1N73 C;  1LWU C;  3H32 B;  2J1G A;  2J3O A;  2J3F A;  2H43 C;  2Z4E C;  1Z3U A;  1LT9 B;  4JZC A;  4R9J A;  2J0Y A;  2J3G A;  3E1I B;  1JC9 A;  3BVH C;  1RE4 C;  2XNX B;  2J0H A;  1FIB A;  1LTJ C;  2J2P A;  2D39 A;  2HPC C;  2OYH B;  1RE3 B;  1FZE B;  3GHG C;  1RF0 B;  1FZF B;  3HUS B;  1M1J C;  2Q9I B;  2JHH C;  1N86 B;  1RF1 B;  4EPU A;  2JHK F;  1FZB C;  2GY7 A;  1FZC C;  2HOD B;  1N73 B;  1LWU B;  1FID A;  1Z3S A;  1FZA C;  1FZG C;  2H43 B;  4ZFG A;  2Z4E B; 
#chains in the Genus database with same CATH topology
 1FZD A;  2J5Z A;  2OYI C;  2FFD C;  2HLO C;  3BVH B;  4NYT A;  2J3F D;  1RE4 B;  2FIB A;  2J0G A;  3H32 C;  1LTJ B;  2J3U A;  2JHM F;  1RF1 C;  4M7F A;  2HPC B;  1LT9 C;  3GHG B;  3E1I C;  1M1J B;  4JYO X;  2JHI F;  2WNP F;  2XNX C;  1FZB B;  1FZC B;  2OYH C;  1FIC A;  1RE3 C;  1FZE C;  1RF0 C;  1FZA B;  2J61 B;  1FZF C;  1FZG B;  4M7H A;  3HUS C;  4R9T A;  2Q9I C;  1N86 C;  3FIB A;  2JHL F;  2J64 A;  2FFD B;  2J61 A;  2OYI B;  2J60 A;  2HLO B;  2HOD C;  1N73 C;  1LWU C;  3H32 B;  2J1G A;  2J3O A;  2J3F A;  2H43 C;  2Z4E C;  1Z3U A;  1LT9 B;  4JZC A;  4R9J A;  2J0Y A;  2J3G A;  3E1I B;  1JC9 A;  3BVH C;  1RE4 C;  2XNX B;  2J0H A;  1FIB A;  1LTJ C;  2J2P A;  2D39 A;  2HPC C;  2OYH B;  1RE3 B;  1FZE B;  3GHG C;  1RF0 B;  1FZF B;  3HUS B;  1M1J C;  2Q9I B;  2JHH C;  1N86 B;  1RF1 B;  4EPU A;  2JHK F;  1FZB C;  2GY7 A;  1FZC C;  2HOD B;  1N73 B;  1LWU B;  1FID A;  1Z3S A;  1FZA C;  1FZG C;  2H43 B;  4ZFG A;  2Z4E B; 
#chains in the Genus database with same CATH homology
 1FZD A;  2J5Z A;  2OYI C;  2FFD C;  2HLO C;  3BVH B;  4NYT A;  2J3F D;  1RE4 B;  2FIB A;  2J0G A;  3H32 C;  1LTJ B;  2J3U A;  2JHM F;  1RF1 C;  4M7F A;  2HPC B;  1LT9 C;  3E1I C;  1M1J B;  4JYO X;  2JHI F;  2WNP F;  2XNX C;  1FZB B;  1FZC B;  2OYH C;  1FIC A;  1RE3 C;  1FZE C;  1RF0 C;  1FZA B;  2J61 B;  1FZF C;  1FZG B;  4M7H A;  3HUS C;  4R9T A;  2Q9I C;  1N86 C;  3FIB A;  2JHL F;  2J64 A;  2FFD B;  2J61 A;  2OYI B;  2J60 A;  2HLO B;  2HOD C;  1N73 C;  1LWU C;  3H32 B;  2J1G A;  2J3O A;  2J3F A;  2H43 C;  2Z4E C;  1Z3U A;  1LT9 B;  4JZC A;  4R9J A;  2J0Y A;  2J3G A;  3E1I B;  1JC9 A;  3BVH C;  1RE4 C;  2XNX B;  2J0H A;  1FIB A;  1LTJ C;  2J2P A;  2D39 A;  2HPC C;  2OYH B;  1RE3 B;  1FZE B;  3GHG C;  1RF0 B;  1FZF B;  3HUS B;  1M1J C;  2Q9I B;  2JHH C;  1N86 B;  1RF1 B;  4EPU A;  2JHK F;  1FZB C;  2GY7 A;  1FZC C;  2HOD B;  1N73 B;  1LWU B;  1FID A;  1Z3S A;  1FZA C;  1FZG C;  2H43 B;  4ZFG A;  2Z4E B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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