2JHLF

Structure of globular heads of m-ficolin complexed with sialic acid
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 75
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhlF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhlF02
1FICA 2J0YA 1FZBB 4R9TA 1RF0C 2J3GA 2HODC 1LTJC 2Q9IB 2Z4EC 2J0GA 2JHLF 4M7FA 2J3OA 2OYIC 1N73B 4JZCA 1FZBC 1FZGB 2J1GA 2Q9IC 1FZCB 2HLOB 2Z4EB 3H32B 3E1IB 2OYIB 2J3FA 2J0HA 1FZGC 1LT9C 1RE4B 3GHGC 1FZCC 2HLOC 2JHMF 3H32C 1FIDA 2J61A 3E1IC 1M1JC 4NYTA 4M7HA 3HUSC 2J2PA 1LT9B 1RE4C 2JHKF 3FIBA 1RE3B 1FZAC 1Z3UA 2JHHC 1M1JB 2D39A 2XNXB 2WNPF 3HUSB 4JYOX 2GY7A 3BVHC 1FZDA 1FZEC 2JHIF 1RE3C 2J60A 1FZAB 2HPCB 2OYHC 2XNXC 1RF1C 1LWUB 2FIBA 1FZFC 2FFDC 2J3FD 1JC9A 3BVHB 2H43C 1FZEB 2J3UA 2HPCC 2OYHB 1N86B 2J61B 4EPUA 1LWUC 1RF1B 1FZFB 1Z3SA 2FFDB 4R9JA 2H43B 2J5ZA 1RF0B 1N86C 2J64A 2HODB 1LTJB 4ZFGA 1FIBA 1N73C
chains in the Genus database with same CATH superfamily
1FICA 2J0YA 1FZBB 4R9TA 1RF0C 2J3GA 2HODC 1LTJC 2Q9IB 2Z4EC 2J0GA 2JHLF 4M7FA 2J3OA 2OYIC 1N73B 4JZCA 1FZBC 1FZGB 2J1GA 2Q9IC 3GHGB 1FZCB 2HLOB 2Z4EB 3H32B 3E1IB 2OYIB 2J3FA 2J0HA 1FZGC 1LT9C 1RE4B 3GHGC 1FZCC 2HLOC 2JHMF 3H32C 1FIDA 2J61A 3E1IC 1M1JC 4NYTA 4M7HA 3HUSC 2J2PA 1LT9B 1RE4C 2JHKF 3FIBA 1RE3B 1FZAC 1Z3UA 2JHHC 1M1JB 2D39A 2XNXB 2WNPF 3HUSB 4JYOX 2GY7A 3BVHC 1FZDA 1FZEC 2JHIF 1RE3C 2J60A 1FZAB 2HPCB 2OYHC 2XNXC 1RF1C 1LWUB 2FIBA 1FZFC 2FFDC 2J3FD 1JC9A 3BVHB 2H43C 1FZEB 2J3UA 2HPCC 2OYHB 1N86B 2J61B 4EPUA 1LWUC 1RF1B 1FZFB 1Z3SA 2FFDB 4R9JA 2H43B 2J5ZA 1RF0B 1N86C 2J64A 2HODB 1LTJB 4ZFGA 1FIBA 1N73C
chains in the Genus database with same CATH topology
1FICA 2J0YA 1FZBB 4R9TA 1RF0C 2J3GA 2HODC 1LTJC 2Q9IB 2Z4EC 2J0GA 2JHLF 4M7FA 2J3OA 2OYIC 1N73B 4JZCA 1FZBC 1FZGB 2J1GA 2Q9IC 1FZCB 2HLOB 2Z4EB 3H32B 3E1IB 2OYIB 2J3FA 2J0HA 1FZGC 1LT9C 1RE4B 3GHGC 1FZCC 2HLOC 2JHMF 3H32C 1FIDA 2J61A 3E1IC 1M1JC 4NYTA 4M7HA 3HUSC 2J2PA 1LT9B 1RE4C 2JHKF 3FIBA 1RE3B 1FZAC 1Z3UA 2JHHC 1M1JB 2D39A 2XNXB 2WNPF 3HUSB 4JYOX 2GY7A 3BVHC 1FZDA 1FZEC 2JHIF 1RE3C 2J60A 1FZAB 2HPCB 2OYHC 2XNXC 1RF1C 1LWUB 2FIBA 1FZFC 2FFDC 2J3FD 1JC9A 3BVHB 2H43C 1FZEB 2J3UA 2HPCC 2OYHB 1N86B 2J61B 4EPUA 1LWUC 1RF1B 1FZFB 1Z3SA 2FFDB 4R9JA 2H43B 2J5ZA 1RF0B 1N86C 2J64A 2HODB 1LTJB 4ZFGA 1FIBA 1N73C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FIC A;  2J0Y A;  1FZB B;  4R9T A;  1RF0 C;  2J3G A;  2HOD C;  1LTJ C;  2Q9I B;  2Z4E C;  2J0G A;  2JHL F;  4M7F A;  2J3O A;  2OYI C;  1N73 B;  4JZC A;  1FZB C;  1FZG B;  2J1G A;  2Q9I C;  1FZC B;  2HLO B;  2Z4E B;  3H32 B;  3E1I B;  2OYI B;  2J3F A;  2J0H A;  1FZG C;  1LT9 C;  1RE4 B;  3GHG C;  1FZC C;  2HLO C;  2JHM F;  3H32 C;  1FID A;  2J61 A;  3E1I C;  1M1J C;  4NYT A;  4M7H A;  3HUS C;  2J2P A;  1LT9 B;  1RE4 C;  2JHK F;  3FIB A;  1RE3 B;  1FZA C;  1Z3U A;  2JHH C;  1M1J B;  2D39 A;  2XNX B;  2WNP F;  3HUS B;  4JYO X;  2GY7 A;  3BVH C;  1FZD A;  1FZE C;  2JHI F;  1RE3 C;  2J60 A;  1FZA B;  2HPC B;  2OYH C;  2XNX C;  1RF1 C;  1LWU B;  2FIB A;  1FZF C;  2FFD C;  2J3F D;  1JC9 A;  3BVH B;  2H43 C;  1FZE B;  2J3U A;  2HPC C;  2OYH B;  1N86 B;  2J61 B;  4EPU A;  1LWU C;  1RF1 B;  1FZF B;  1Z3S A;  2FFD B;  4R9J A;  2H43 B;  2J5Z A;  1RF0 B;  1N86 C;  2J64 A;  2HOD B;  1LTJ B;  4ZFG A;  1FIB A;  1N73 C; 
#chains in the Genus database with same CATH topology
 1FIC A;  2J0Y A;  1FZB B;  4R9T A;  1RF0 C;  2J3G A;  2HOD C;  1LTJ C;  2Q9I B;  2Z4E C;  2J0G A;  2JHL F;  4M7F A;  2J3O A;  2OYI C;  1N73 B;  4JZC A;  1FZB C;  1FZG B;  2J1G A;  2Q9I C;  3GHG B;  1FZC B;  2HLO B;  2Z4E B;  3H32 B;  3E1I B;  2OYI B;  2J3F A;  2J0H A;  1FZG C;  1LT9 C;  1RE4 B;  3GHG C;  1FZC C;  2HLO C;  2JHM F;  3H32 C;  1FID A;  2J61 A;  3E1I C;  1M1J C;  4NYT A;  4M7H A;  3HUS C;  2J2P A;  1LT9 B;  1RE4 C;  2JHK F;  3FIB A;  1RE3 B;  1FZA C;  1Z3U A;  2JHH C;  1M1J B;  2D39 A;  2XNX B;  2WNP F;  3HUS B;  4JYO X;  2GY7 A;  3BVH C;  1FZD A;  1FZE C;  2JHI F;  1RE3 C;  2J60 A;  1FZA B;  2HPC B;  2OYH C;  2XNX C;  1RF1 C;  1LWU B;  2FIB A;  1FZF C;  2FFD C;  2J3F D;  1JC9 A;  3BVH B;  2H43 C;  1FZE B;  2J3U A;  2HPC C;  2OYH B;  1N86 B;  2J61 B;  4EPU A;  1LWU C;  1RF1 B;  1FZF B;  1Z3S A;  2FFD B;  4R9J A;  2H43 B;  2J5Z A;  1RF0 B;  1N86 C;  2J64 A;  2HOD B;  1LTJ B;  4ZFG A;  1FIB A;  1N73 C; 
#chains in the Genus database with same CATH homology
 1FIC A;  2J0Y A;  1FZB B;  4R9T A;  1RF0 C;  2J3G A;  2HOD C;  1LTJ C;  2Q9I B;  2Z4E C;  2J0G A;  2JHL F;  4M7F A;  2J3O A;  2OYI C;  1N73 B;  4JZC A;  1FZB C;  1FZG B;  2J1G A;  2Q9I C;  1FZC B;  2HLO B;  2Z4E B;  3H32 B;  3E1I B;  2OYI B;  2J3F A;  2J0H A;  1FZG C;  1LT9 C;  1RE4 B;  3GHG C;  1FZC C;  2HLO C;  2JHM F;  3H32 C;  1FID A;  2J61 A;  3E1I C;  1M1J C;  4NYT A;  4M7H A;  3HUS C;  2J2P A;  1LT9 B;  1RE4 C;  2JHK F;  3FIB A;  1RE3 B;  1FZA C;  1Z3U A;  2JHH C;  1M1J B;  2D39 A;  2XNX B;  2WNP F;  3HUS B;  4JYO X;  2GY7 A;  3BVH C;  1FZD A;  1FZE C;  2JHI F;  1RE3 C;  2J60 A;  1FZA B;  2HPC B;  2OYH C;  2XNX C;  1RF1 C;  1LWU B;  2FIB A;  1FZF C;  2FFD C;  2J3F D;  1JC9 A;  3BVH B;  2H43 C;  1FZE B;  2J3U A;  2HPC C;  2OYH B;  1N86 B;  2J61 B;  4EPU A;  1LWU C;  1RF1 B;  1FZF B;  1Z3S A;  2FFD B;  4R9J A;  2H43 B;  2J5Z A;  1RF0 B;  1N86 C;  2J64 A;  2HOD B;  1LTJ B;  4ZFG A;  1FIB A;  1N73 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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