2Q9IB

Crystal structure of d-dimer from human fibrin complexed with met-his-arg-pro-tyr-amide.
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 90
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2q9iB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2q9iB02
1RE4C 1FZGB 2OYIB 3E1IB 2J3FA 1LTJC 1FZFB 2J61B 2J3OA 2J61A 4M7FA 1FZAB 1FZCC 1FZEB 3HUSB 2JHKF 1RE4B 1FZDA 2FFDB 4M7HA 4EPUA 2FFDC 2WNPF 2FIBA 1LTJB 2HODC 2J0HA 1RF0C 4JYOX 1RE3C 2J60A 2JHLF 1FZCB 2Q9IB 3GHGC 4NYTA 3H32C 2HLOC 2J2PA 2Q9IC 2J3FD 2JHMF 2JHHC 1N73B 2JHIF 2OYHC 2HODB 2Z4EC 1LT9C 1FIBA 1N73C 1FZBC 1RF0B 1RE3B 1Z3UA 1FICA 1N86C 1RF1C 3BVHC 2J3GA 1JC9A 3H32B 2HLOB 2J0GA 2J3UA 2XNXC 3FIBA 2D39A 2OYHB 4R9TA 2Z4EB 1LT9B 1FIDA 2GY7A 1M1JB 2H43B 1FZBB 1LWUB 1N86B 1FZGC 1RF1B 2J64A 4JZCA 3BVHB 2J5ZA 1M1JC 2OYIC 2H43C 3E1IC 2HPCB 1LWUC 4R9JA 1FZFC 2HPCC 1Z3SA 2J0YA 2XNXB 1FZAC 1FZEC 3HUSC 4ZFGA 2J1GA
chains in the Genus database with same CATH superfamily
1RE4C 1FZGB 2OYIB 3E1IB 2J3FA 1LTJC 1FZFB 2J61B 2J3OA 2J61A 4M7FA 1FZAB 1FZCC 1FZEB 3HUSB 2JHKF 1RE4B 1FZDA 2FFDB 4M7HA 4EPUA 2FFDC 2WNPF 2FIBA 1LTJB 2HODC 2J0HA 1RF0C 4JYOX 1RE3C 2J60A 2JHLF 1FZCB 2Q9IB 3GHGC 4NYTA 3H32C 2HLOC 2J2PA 2Q9IC 2J3FD 2JHMF 2JHHC 1N73B 2JHIF 2OYHC 2HODB 2Z4EC 1LT9C 1FIBA 1N73C 1FZBC 1RF0B 1RE3B 1Z3UA 1FICA 1N86C 1RF1C 3BVHC 2J3GA 3GHGB 1JC9A 3H32B 2HLOB 2J0GA 2J3UA 2XNXC 3FIBA 2D39A 2OYHB 4R9TA 2Z4EB 1LT9B 1FIDA 2GY7A 1M1JB 2H43B 1FZBB 1LWUB 1N86B 1FZGC 1RF1B 2J64A 4JZCA 3BVHB 2J5ZA 1M1JC 2OYIC 2H43C 3E1IC 2HPCB 1LWUC 4R9JA 1FZFC 2HPCC 1Z3SA 2J0YA 2XNXB 1FZAC 1FZEC 3HUSC 4ZFGA 2J1GA
chains in the Genus database with same CATH topology
1RE4C 1FZGB 2OYIB 3E1IB 2J3FA 1LTJC 1FZFB 2J61B 2J3OA 2J61A 4M7FA 1FZAB 1FZCC 1FZEB 3HUSB 2JHKF 1RE4B 1FZDA 2FFDB 4M7HA 4EPUA 2FFDC 2WNPF 2FIBA 1LTJB 2HODC 2J0HA 1RF0C 4JYOX 1RE3C 2J60A 2JHLF 1FZCB 2Q9IB 3GHGC 4NYTA 3H32C 2HLOC 2J2PA 2Q9IC 2J3FD 2JHMF 2JHHC 1N73B 2JHIF 2OYHC 2HODB 2Z4EC 1LT9C 1FIBA 1N73C 1FZBC 1RF0B 1RE3B 1Z3UA 1FICA 1N86C 1RF1C 3BVHC 2J3GA 1JC9A 3H32B 2HLOB 2J0GA 2J3UA 2XNXC 3FIBA 2D39A 2OYHB 4R9TA 2Z4EB 1LT9B 1FIDA 2GY7A 1M1JB 2H43B 1FZBB 1LWUB 1N86B 1FZGC 1RF1B 2J64A 4JZCA 3BVHB 2J5ZA 1M1JC 2OYIC 2H43C 3E1IC 2HPCB 1LWUC 4R9JA 1FZFC 2HPCC 1Z3SA 2J0YA 2XNXB 1FZAC 1FZEC 3HUSC 4ZFGA 2J1GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RE4 C;  1FZG B;  2OYI B;  3E1I B;  2J3F A;  1LTJ C;  1FZF B;  2J61 B;  2J3O A;  2J61 A;  4M7F A;  1FZA B;  1FZC C;  1FZE B;  3HUS B;  2JHK F;  1RE4 B;  1FZD A;  2FFD B;  4M7H A;  4EPU A;  2FFD C;  2WNP F;  2FIB A;  1LTJ B;  2HOD C;  2J0H A;  1RF0 C;  4JYO X;  1RE3 C;  2J60 A;  2JHL F;  1FZC B;  2Q9I B;  3GHG C;  4NYT A;  3H32 C;  2HLO C;  2J2P A;  2Q9I C;  2J3F D;  2JHM F;  2JHH C;  1N73 B;  2JHI F;  2OYH C;  2HOD B;  2Z4E C;  1LT9 C;  1FIB A;  1N73 C;  1FZB C;  1RF0 B;  1RE3 B;  1Z3U A;  1FIC A;  1N86 C;  1RF1 C;  3BVH C;  2J3G A;  1JC9 A;  3H32 B;  2HLO B;  2J0G A;  2J3U A;  2XNX C;  3FIB A;  2D39 A;  2OYH B;  4R9T A;  2Z4E B;  1LT9 B;  1FID A;  2GY7 A;  1M1J B;  2H43 B;  1FZB B;  1LWU B;  1N86 B;  1FZG C;  1RF1 B;  2J64 A;  4JZC A;  3BVH B;  2J5Z A;  1M1J C;  2OYI C;  2H43 C;  3E1I C;  2HPC B;  1LWU C;  4R9J A;  1FZF C;  2HPC C;  1Z3S A;  2J0Y A;  2XNX B;  1FZA C;  1FZE C;  3HUS C;  4ZFG A;  2J1G A; 
#chains in the Genus database with same CATH topology
 1RE4 C;  1FZG B;  2OYI B;  3E1I B;  2J3F A;  1LTJ C;  1FZF B;  2J61 B;  2J3O A;  2J61 A;  4M7F A;  1FZA B;  1FZC C;  1FZE B;  3HUS B;  2JHK F;  1RE4 B;  1FZD A;  2FFD B;  4M7H A;  4EPU A;  2FFD C;  2WNP F;  2FIB A;  1LTJ B;  2HOD C;  2J0H A;  1RF0 C;  4JYO X;  1RE3 C;  2J60 A;  2JHL F;  1FZC B;  2Q9I B;  3GHG C;  4NYT A;  3H32 C;  2HLO C;  2J2P A;  2Q9I C;  2J3F D;  2JHM F;  2JHH C;  1N73 B;  2JHI F;  2OYH C;  2HOD B;  2Z4E C;  1LT9 C;  1FIB A;  1N73 C;  1FZB C;  1RF0 B;  1RE3 B;  1Z3U A;  1FIC A;  1N86 C;  1RF1 C;  3BVH C;  2J3G A;  3GHG B;  1JC9 A;  3H32 B;  2HLO B;  2J0G A;  2J3U A;  2XNX C;  3FIB A;  2D39 A;  2OYH B;  4R9T A;  2Z4E B;  1LT9 B;  1FID A;  2GY7 A;  1M1J B;  2H43 B;  1FZB B;  1LWU B;  1N86 B;  1FZG C;  1RF1 B;  2J64 A;  4JZC A;  3BVH B;  2J5Z A;  1M1J C;  2OYI C;  2H43 C;  3E1I C;  2HPC B;  1LWU C;  4R9J A;  1FZF C;  2HPC C;  1Z3S A;  2J0Y A;  2XNX B;  1FZA C;  1FZE C;  3HUS C;  4ZFG A;  2J1G A; 
#chains in the Genus database with same CATH homology
 1RE4 C;  1FZG B;  2OYI B;  3E1I B;  2J3F A;  1LTJ C;  1FZF B;  2J61 B;  2J3O A;  2J61 A;  4M7F A;  1FZA B;  1FZC C;  1FZE B;  3HUS B;  2JHK F;  1RE4 B;  1FZD A;  2FFD B;  4M7H A;  4EPU A;  2FFD C;  2WNP F;  2FIB A;  1LTJ B;  2HOD C;  2J0H A;  1RF0 C;  4JYO X;  1RE3 C;  2J60 A;  2JHL F;  1FZC B;  2Q9I B;  3GHG C;  4NYT A;  3H32 C;  2HLO C;  2J2P A;  2Q9I C;  2J3F D;  2JHM F;  2JHH C;  1N73 B;  2JHI F;  2OYH C;  2HOD B;  2Z4E C;  1LT9 C;  1FIB A;  1N73 C;  1FZB C;  1RF0 B;  1RE3 B;  1Z3U A;  1FIC A;  1N86 C;  1RF1 C;  3BVH C;  2J3G A;  1JC9 A;  3H32 B;  2HLO B;  2J0G A;  2J3U A;  2XNX C;  3FIB A;  2D39 A;  2OYH B;  4R9T A;  2Z4E B;  1LT9 B;  1FID A;  2GY7 A;  1M1J B;  2H43 B;  1FZB B;  1LWU B;  1N86 B;  1FZG C;  1RF1 B;  2J64 A;  4JZC A;  3BVH B;  2J5Z A;  1M1J C;  2OYI C;  2H43 C;  3E1I C;  2HPC B;  1LWU C;  4R9J A;  1FZF C;  2HPC C;  1Z3S A;  2J0Y A;  2XNX B;  1FZA C;  1FZE C;  3HUS C;  4ZFG A;  2J1G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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