2Q9IC

Crystal structure of d-dimer from human fibrin complexed with met-his-arg-pro-tyr-amide.
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 80
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2q9iC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2q9iC02
1LTJB 1LT9C 1LWUB 2FFDC 1RE4B 2J0YA 1FZCC 2FFDB 1FZGB 1JC9A 1FZAC 1FZAB 3BVHC 2J3OA 2HLOC 3BVHB 2OYIC 2OYIB 3E1IB 1RE3C 4NYTA 2JHKF 2GY7A 1Z3SA 2J61A 2XNXC 3FIBA 2JHIF 1LT9B 2J2PA 1RF0C 1FZCB 1N86C 2J61B 1RF0B 4M7FA 1FZFC 3GHGC 2JHLF 1FZFB 2JHHC 3H32C 2J1GA 3H32B 2OYHC 4ZFGA 2HPCC 2OYHB 2J0HA 2HLOB 1FZBC 2J3FD 2HPCB 1FZBB 1RE3B 2H43C 1FIDA 2XNXB 2H43B 4EPUA 4JZCA 2JHMF 1RF1C 1N86B 2J64A 2Q9IC 1RF1B 2J3GA 2Z4EC 2Q9IB 2Z4EB 1FICA 3HUSC 4M7HA 2J3FA 3HUSB 1FZEC 1LTJC 1FIBA 1LWUC 4R9JA 1RE4C 2D39A 2J3UA 2WNPF 1FZGC 4JYOX 2J60A 1FZDA 2FIBA 2HODC 1N73C 2HODB 1N73B 3E1IC 2J5ZA 1Z3UA 4R9TA 1M1JC 2J0GA 1M1JB 1FZEB
chains in the Genus database with same CATH superfamily
1LTJB 1LT9C 1LWUB 2FFDC 1RE4B 2J0YA 1FZCC 2FFDB 1FZGB 1JC9A 1FZAC 1FZAB 3BVHC 2J3OA 2HLOC 3BVHB 2OYIC 2OYIB 3E1IB 1RE3C 4NYTA 2JHKF 2GY7A 1Z3SA 2J61A 2XNXC 3FIBA 2JHIF 1LT9B 2J2PA 1RF0C 1FZCB 1N86C 2J61B 1RF0B 4M7FA 1FZFC 3GHGC 2JHLF 1FZFB 2JHHC 3H32C 2J1GA 3H32B 2OYHC 4ZFGA 2HPCC 2OYHB 2J0HA 2HLOB 1FZBC 2J3FD 2HPCB 1FZBB 1RE3B 2H43C 1FIDA 2XNXB 2H43B 4EPUA 4JZCA 2JHMF 1RF1C 1N86B 2J64A 2Q9IC 1RF1B 2J3GA 2Z4EC 2Q9IB 2Z4EB 1FICA 3GHGB 3HUSC 4M7HA 2J3FA 3HUSB 1FZEC 1LTJC 1FIBA 1LWUC 4R9JA 1RE4C 2D39A 2J3UA 2WNPF 1FZGC 4JYOX 2J60A 1FZDA 2FIBA 2HODC 1N73C 2HODB 1N73B 3E1IC 2J5ZA 1Z3UA 4R9TA 1M1JC 2J0GA 1M1JB 1FZEB
chains in the Genus database with same CATH topology
1LTJB 1LT9C 1LWUB 2FFDC 1RE4B 2J0YA 1FZCC 2FFDB 1FZGB 1JC9A 1FZAC 1FZAB 3BVHC 2J3OA 2HLOC 3BVHB 2OYIC 2OYIB 3E1IB 1RE3C 4NYTA 2JHKF 2GY7A 1Z3SA 2J61A 2XNXC 3FIBA 2JHIF 1LT9B 2J2PA 1RF0C 1FZCB 1N86C 2J61B 1RF0B 4M7FA 1FZFC 3GHGC 2JHLF 1FZFB 2JHHC 3H32C 2J1GA 3H32B 2OYHC 4ZFGA 2HPCC 2OYHB 2J0HA 2HLOB 1FZBC 2J3FD 2HPCB 1FZBB 1RE3B 2H43C 1FIDA 2XNXB 2H43B 4EPUA 4JZCA 2JHMF 1RF1C 1N86B 2J64A 2Q9IC 1RF1B 2J3GA 2Z4EC 2Q9IB 2Z4EB 1FICA 3HUSC 4M7HA 2J3FA 3HUSB 1FZEC 1LTJC 1FIBA 1LWUC 4R9JA 1RE4C 2D39A 2J3UA 2WNPF 1FZGC 4JYOX 2J60A 1FZDA 2FIBA 2HODC 1N73C 2HODB 1N73B 3E1IC 2J5ZA 1Z3UA 4R9TA 1M1JC 2J0GA 1M1JB 1FZEB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LTJ B;  1LT9 C;  1LWU B;  2FFD C;  1RE4 B;  2J0Y A;  1FZC C;  2FFD B;  1FZG B;  1JC9 A;  1FZA C;  1FZA B;  3BVH C;  2J3O A;  2HLO C;  3BVH B;  2OYI C;  2OYI B;  3E1I B;  1RE3 C;  4NYT A;  2JHK F;  2GY7 A;  1Z3S A;  2J61 A;  2XNX C;  3FIB A;  2JHI F;  1LT9 B;  2J2P A;  1RF0 C;  1FZC B;  1N86 C;  2J61 B;  1RF0 B;  4M7F A;  1FZF C;  3GHG C;  2JHL F;  1FZF B;  2JHH C;  3H32 C;  2J1G A;  3H32 B;  2OYH C;  4ZFG A;  2HPC C;  2OYH B;  2J0H A;  2HLO B;  1FZB C;  2J3F D;  2HPC B;  1FZB B;  1RE3 B;  2H43 C;  1FID A;  2XNX B;  2H43 B;  4EPU A;  4JZC A;  2JHM F;  1RF1 C;  1N86 B;  2J64 A;  2Q9I C;  1RF1 B;  2J3G A;  2Z4E C;  2Q9I B;  2Z4E B;  1FIC A;  3HUS C;  4M7H A;  2J3F A;  3HUS B;  1FZE C;  1LTJ C;  1FIB A;  1LWU C;  4R9J A;  1RE4 C;  2D39 A;  2J3U A;  2WNP F;  1FZG C;  4JYO X;  2J60 A;  1FZD A;  2FIB A;  2HOD C;  1N73 C;  2HOD B;  1N73 B;  3E1I C;  2J5Z A;  1Z3U A;  4R9T A;  1M1J C;  2J0G A;  1M1J B;  1FZE B; 
#chains in the Genus database with same CATH topology
 1LTJ B;  1LT9 C;  1LWU B;  2FFD C;  1RE4 B;  2J0Y A;  1FZC C;  2FFD B;  1FZG B;  1JC9 A;  1FZA C;  1FZA B;  3BVH C;  2J3O A;  2HLO C;  3BVH B;  2OYI C;  2OYI B;  3E1I B;  1RE3 C;  4NYT A;  2JHK F;  2GY7 A;  1Z3S A;  2J61 A;  2XNX C;  3FIB A;  2JHI F;  1LT9 B;  2J2P A;  1RF0 C;  1FZC B;  1N86 C;  2J61 B;  1RF0 B;  4M7F A;  1FZF C;  3GHG C;  2JHL F;  1FZF B;  2JHH C;  3H32 C;  2J1G A;  3H32 B;  2OYH C;  4ZFG A;  2HPC C;  2OYH B;  2J0H A;  2HLO B;  1FZB C;  2J3F D;  2HPC B;  1FZB B;  1RE3 B;  2H43 C;  1FID A;  2XNX B;  2H43 B;  4EPU A;  4JZC A;  2JHM F;  1RF1 C;  1N86 B;  2J64 A;  2Q9I C;  1RF1 B;  2J3G A;  2Z4E C;  2Q9I B;  2Z4E B;  1FIC A;  3GHG B;  3HUS C;  4M7H A;  2J3F A;  3HUS B;  1FZE C;  1LTJ C;  1FIB A;  1LWU C;  4R9J A;  1RE4 C;  2D39 A;  2J3U A;  2WNP F;  1FZG C;  4JYO X;  2J60 A;  1FZD A;  2FIB A;  2HOD C;  1N73 C;  2HOD B;  1N73 B;  3E1I C;  2J5Z A;  1Z3U A;  4R9T A;  1M1J C;  2J0G A;  1M1J B;  1FZE B; 
#chains in the Genus database with same CATH homology
 1LTJ B;  1LT9 C;  1LWU B;  2FFD C;  1RE4 B;  2J0Y A;  1FZC C;  2FFD B;  1FZG B;  1JC9 A;  1FZA C;  1FZA B;  3BVH C;  2J3O A;  2HLO C;  3BVH B;  2OYI C;  2OYI B;  3E1I B;  1RE3 C;  4NYT A;  2JHK F;  2GY7 A;  1Z3S A;  2J61 A;  2XNX C;  3FIB A;  2JHI F;  1LT9 B;  2J2P A;  1RF0 C;  1FZC B;  1N86 C;  2J61 B;  1RF0 B;  4M7F A;  1FZF C;  3GHG C;  2JHL F;  1FZF B;  2JHH C;  3H32 C;  2J1G A;  3H32 B;  2OYH C;  4ZFG A;  2HPC C;  2OYH B;  2J0H A;  2HLO B;  1FZB C;  2J3F D;  2HPC B;  1FZB B;  1RE3 B;  2H43 C;  1FID A;  2XNX B;  2H43 B;  4EPU A;  4JZC A;  2JHM F;  1RF1 C;  1N86 B;  2J64 A;  2Q9I C;  1RF1 B;  2J3G A;  2Z4E C;  2Q9I B;  2Z4E B;  1FIC A;  3HUS C;  4M7H A;  2J3F A;  3HUS B;  1FZE C;  1LTJ C;  1FIB A;  1LWU C;  4R9J A;  1RE4 C;  2D39 A;  2J3U A;  2WNP F;  1FZG C;  4JYO X;  2J60 A;  1FZD A;  2FIB A;  2HOD C;  1N73 C;  2HOD B;  1N73 B;  3E1I C;  2J5Z A;  1Z3U A;  4R9T A;  1M1J C;  2J0G A;  1M1J B;  1FZE B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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