2WNPF

M-ficolin mutant y271f
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESFANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Carbohydrate Recognition Properties of Human Ficolins: Glycan Array Screening Reveals the Sialic Acid Binding Specificity of M-Ficolin.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 76
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2009-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2wnpF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2wnpF02
1FZGC 1N86C 2J60A 2XNXB 2FFDC 1FZGB 1LTJC 1FZAC 2H43B 1LTJB 2WNPF 1FIDA 2OYHB 2FIBA 2Z4EC 2OYIC 1FIBA 2Z4EB 2J2PA 4JYOX 2OYIB 2J0HA 1RE4B 3HUSC 1FZBC 3E1IC 1FZFC 3HUSB 1FZEC 2HODC 4M7HA 1N86B 2FFDB 3BVHC 2HODB 4R9TA 3H32C 1FZAB 2JHHC 3H32B 2JHLF 1FZDA 1RE3C 2J0YA 4M7FA 2Q9IC 4EPUA 2J64A 2J3UA 1Z3UA 2J3OA 1FZCC 1RF1C 1FZCB 1M1JC 1LT9C 2JHKF 1FZBB 2HPCC 1RF1B 3E1IB 1LT9B 1FZFB 2J1GA 2HPCB 1FZEB 3BVHB 4NYTA 2J3FA 1JC9A 1Z3SA 1LWUC 2JHIF 2J61B 4JZCA 1RE3B 2HLOC 2Q9IB 2XNXC 2HLOB 4ZFGA 2J5ZA 1RF0C 3GHGC 2H43C 1RF0B 3FIBA 1M1JB 2OYHC 2JHMF 2GY7A 2J0GA 2D39A 2J3FD 1RE4C 1N73C 4R9JA 1LWUB 2J3GA 1N73B 1FICA 2J61A
chains in the Genus database with same CATH superfamily
1FZGC 1N86C 2J60A 2XNXB 2FFDC 1FZGB 1LTJC 1FZAC 3GHGB 2H43B 1LTJB 2WNPF 1FIDA 2OYHB 2FIBA 2Z4EC 2OYIC 1FIBA 2Z4EB 2J2PA 4JYOX 2OYIB 2J0HA 1RE4B 3HUSC 1FZBC 3E1IC 1FZFC 3HUSB 1FZEC 2HODC 4M7HA 1N86B 2FFDB 3BVHC 2HODB 4R9TA 3H32C 1FZAB 2JHHC 3H32B 2JHLF 1FZDA 1RE3C 2J0YA 4M7FA 2Q9IC 4EPUA 2J64A 2J3UA 1Z3UA 2J3OA 1FZCC 1RF1C 1FZCB 1M1JC 1LT9C 2JHKF 1FZBB 2HPCC 1RF1B 3E1IB 1LT9B 1FZFB 2J1GA 2HPCB 1FZEB 3BVHB 4NYTA 2J3FA 1JC9A 1Z3SA 1LWUC 2JHIF 2J61B 4JZCA 1RE3B 2HLOC 2Q9IB 2XNXC 2HLOB 4ZFGA 2J5ZA 1RF0C 3GHGC 2H43C 1RF0B 3FIBA 1M1JB 2OYHC 2JHMF 2GY7A 2J0GA 2D39A 2J3FD 1RE4C 1N73C 4R9JA 1LWUB 2J3GA 1N73B 1FICA 2J61A
chains in the Genus database with same CATH topology
1FZGC 1N86C 2J60A 2XNXB 2FFDC 1FZGB 1LTJC 1FZAC 2H43B 1LTJB 2WNPF 1FIDA 2OYHB 2FIBA 2Z4EC 2OYIC 1FIBA 2Z4EB 2J2PA 4JYOX 2OYIB 2J0HA 1RE4B 3HUSC 1FZBC 3E1IC 1FZFC 3HUSB 1FZEC 2HODC 4M7HA 1N86B 2FFDB 3BVHC 2HODB 4R9TA 3H32C 1FZAB 2JHHC 3H32B 2JHLF 1FZDA 1RE3C 2J0YA 4M7FA 2Q9IC 4EPUA 2J64A 2J3UA 1Z3UA 2J3OA 1FZCC 1RF1C 1FZCB 1M1JC 1LT9C 2JHKF 1FZBB 2HPCC 1RF1B 3E1IB 1LT9B 1FZFB 2J1GA 2HPCB 1FZEB 3BVHB 4NYTA 2J3FA 1JC9A 1Z3SA 1LWUC 2JHIF 2J61B 4JZCA 1RE3B 2HLOC 2Q9IB 2XNXC 2HLOB 4ZFGA 2J5ZA 1RF0C 3GHGC 2H43C 1RF0B 3FIBA 1M1JB 2OYHC 2JHMF 2GY7A 2J0GA 2D39A 2J3FD 1RE4C 1N73C 4R9JA 1LWUB 2J3GA 1N73B 1FICA 2J61A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZG C;  1N86 C;  2J60 A;  2XNX B;  2FFD C;  1FZG B;  1LTJ C;  1FZA C;  2H43 B;  1LTJ B;  2WNP F;  1FID A;  2OYH B;  2FIB A;  2Z4E C;  2OYI C;  1FIB A;  2Z4E B;  2J2P A;  4JYO X;  2OYI B;  2J0H A;  1RE4 B;  3HUS C;  1FZB C;  3E1I C;  1FZF C;  3HUS B;  1FZE C;  2HOD C;  4M7H A;  1N86 B;  2FFD B;  3BVH C;  2HOD B;  4R9T A;  3H32 C;  1FZA B;  2JHH C;  3H32 B;  2JHL F;  1FZD A;  1RE3 C;  2J0Y A;  4M7F A;  2Q9I C;  4EPU A;  2J64 A;  2J3U A;  1Z3U A;  2J3O A;  1FZC C;  1RF1 C;  1FZC B;  1M1J C;  1LT9 C;  2JHK F;  1FZB B;  2HPC C;  1RF1 B;  3E1I B;  1LT9 B;  1FZF B;  2J1G A;  2HPC B;  1FZE B;  3BVH B;  4NYT A;  2J3F A;  1JC9 A;  1Z3S A;  1LWU C;  2JHI F;  2J61 B;  4JZC A;  1RE3 B;  2HLO C;  2Q9I B;  2XNX C;  2HLO B;  4ZFG A;  2J5Z A;  1RF0 C;  3GHG C;  2H43 C;  1RF0 B;  3FIB A;  1M1J B;  2OYH C;  2JHM F;  2GY7 A;  2J0G A;  2D39 A;  2J3F D;  1RE4 C;  1N73 C;  4R9J A;  1LWU B;  2J3G A;  1N73 B;  1FIC A;  2J61 A; 
#chains in the Genus database with same CATH topology
 1FZG C;  1N86 C;  2J60 A;  2XNX B;  2FFD C;  1FZG B;  1LTJ C;  1FZA C;  3GHG B;  2H43 B;  1LTJ B;  2WNP F;  1FID A;  2OYH B;  2FIB A;  2Z4E C;  2OYI C;  1FIB A;  2Z4E B;  2J2P A;  4JYO X;  2OYI B;  2J0H A;  1RE4 B;  3HUS C;  1FZB C;  3E1I C;  1FZF C;  3HUS B;  1FZE C;  2HOD C;  4M7H A;  1N86 B;  2FFD B;  3BVH C;  2HOD B;  4R9T A;  3H32 C;  1FZA B;  2JHH C;  3H32 B;  2JHL F;  1FZD A;  1RE3 C;  2J0Y A;  4M7F A;  2Q9I C;  4EPU A;  2J64 A;  2J3U A;  1Z3U A;  2J3O A;  1FZC C;  1RF1 C;  1FZC B;  1M1J C;  1LT9 C;  2JHK F;  1FZB B;  2HPC C;  1RF1 B;  3E1I B;  1LT9 B;  1FZF B;  2J1G A;  2HPC B;  1FZE B;  3BVH B;  4NYT A;  2J3F A;  1JC9 A;  1Z3S A;  1LWU C;  2JHI F;  2J61 B;  4JZC A;  1RE3 B;  2HLO C;  2Q9I B;  2XNX C;  2HLO B;  4ZFG A;  2J5Z A;  1RF0 C;  3GHG C;  2H43 C;  1RF0 B;  3FIB A;  1M1J B;  2OYH C;  2JHM F;  2GY7 A;  2J0G A;  2D39 A;  2J3F D;  1RE4 C;  1N73 C;  4R9J A;  1LWU B;  2J3G A;  1N73 B;  1FIC A;  2J61 A; 
#chains in the Genus database with same CATH homology
 1FZG C;  1N86 C;  2J60 A;  2XNX B;  2FFD C;  1FZG B;  1LTJ C;  1FZA C;  2H43 B;  1LTJ B;  2WNP F;  1FID A;  2OYH B;  2FIB A;  2Z4E C;  2OYI C;  1FIB A;  2Z4E B;  2J2P A;  4JYO X;  2OYI B;  2J0H A;  1RE4 B;  3HUS C;  1FZB C;  3E1I C;  1FZF C;  3HUS B;  1FZE C;  2HOD C;  4M7H A;  1N86 B;  2FFD B;  3BVH C;  2HOD B;  4R9T A;  3H32 C;  1FZA B;  2JHH C;  3H32 B;  2JHL F;  1FZD A;  1RE3 C;  2J0Y A;  4M7F A;  2Q9I C;  4EPU A;  2J64 A;  2J3U A;  1Z3U A;  2J3O A;  1FZC C;  1RF1 C;  1FZC B;  1M1J C;  1LT9 C;  2JHK F;  1FZB B;  2HPC C;  1RF1 B;  3E1I B;  1LT9 B;  1FZF B;  2J1G A;  2HPC B;  1FZE B;  3BVH B;  4NYT A;  2J3F A;  1JC9 A;  1Z3S A;  1LWU C;  2JHI F;  2J61 B;  4JZC A;  1RE3 B;  2HLO C;  2Q9I B;  2XNX C;  2HLO B;  4ZFG A;  2J5Z A;  1RF0 C;  3GHG C;  2H43 C;  1RF0 B;  3FIB A;  1M1J B;  2OYH C;  2JHM F;  2GY7 A;  2J0G A;  2D39 A;  2J3F D;  1RE4 C;  1N73 C;  4R9J A;  1LWU B;  2J3G A;  1N73 B;  1FIC A;  2J61 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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