2XNXB

Bc1 fragment of streptococcal m1 protein in complex with human fibrinogen
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
312
structure length
312
Chain Sequence
HQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
pubmed doi rcsb
molecule tags Cell adhesion
source organism Streptococcus pyogenes
molecule keywords FIBRINOGEN ALPHA CHAIN
total genus 72
structure length 312
sequence length 312
chains with identical sequence E, H, K
ec nomenclature
pdb deposition date 2010-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2xnxB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2xnxB02
1FZBB 3BVHC 2OYHC 2J60A 1FZFB 2Z4EB 1LT9C 1FICA 2HLOC 1LTJB 2J61A 1RF1B 1LWUB 1M1JC 2J1GA 1RF0B 1Z3SA 4JZCA 1RE3B 3HUSC 1FZDA 2OYIC 3GHGC 4NYTA 3FIBA 1N73C 3E1IC 4ZFGA 2J3UA 2Q9IB 1FZBC 1Z3UA 2H43B 1N86B 1FIBA 2JHIF 2WNPF 1FZFC 2Z4EC 4R9TA 1FIDA 2J3GA 2J3OA 2J64A 2FIBA 4M7HA 1RF1C 1LWUC 2XNXB 4EPUA 1FZCC 1FZEB 2J61B 3H32B 1RF0C 1RE4B 2HPCB 2HODB 1RE3C 4M7FA 4R9JA 1FZAB 1FZGB 2FFDB 2Q9IC 3BVHB 2OYHB 2JHMF 2H43C 2J5ZA 1LTJC 1N86C 1LT9B 4JYOX 2HLOB 2GY7A 2JHLF 2J3FD 2JHHC 2J2PA 2XNXC 1M1JB 2J0YA 1FZEC 3H32C 1RE4C 2HPCC 2J0GA 1JC9A 2HODC 1FZCB 1FZAC 1FZGC 2JHKF 2FFDC 3HUSB 2D39A 2OYIB 2J0HA 2J3FA 1N73B 3E1IB
chains in the Genus database with same CATH superfamily
1FZBB 3BVHC 2OYHC 2J60A 1FZFB 2Z4EB 1LT9C 1FICA 2HLOC 1LTJB 2J61A 1RF1B 1LWUB 1M1JC 2J1GA 1RF0B 1Z3SA 4JZCA 1RE3B 3HUSC 1FZDA 2OYIC 3GHGC 4NYTA 3FIBA 1N73C 3E1IC 4ZFGA 2J3UA 2Q9IB 1FZBC 1Z3UA 2H43B 1N86B 1FIBA 2JHIF 2WNPF 1FZFC 2Z4EC 4R9TA 1FIDA 2J3GA 2J3OA 2J64A 2FIBA 4M7HA 1RF1C 1LWUC 2XNXB 4EPUA 1FZCC 1FZEB 2J61B 3H32B 1RF0C 1RE4B 2HPCB 2HODB 1RE3C 4M7FA 4R9JA 1FZAB 1FZGB 2FFDB 2Q9IC 3BVHB 2OYHB 2JHMF 2H43C 2J5ZA 1LTJC 1N86C 1LT9B 4JYOX 2HLOB 2GY7A 2JHLF 2J3FD 2JHHC 2J2PA 2XNXC 1M1JB 2J0YA 1FZEC 3H32C 1RE4C 2HPCC 2J0GA 1JC9A 2HODC 1FZCB 1FZAC 1FZGC 2JHKF 2FFDC 3HUSB 2D39A 2OYIB 3GHGB 2J0HA 2J3FA 1N73B 3E1IB
chains in the Genus database with same CATH topology
1FZBB 3BVHC 2OYHC 2J60A 1FZFB 2Z4EB 1LT9C 1FICA 2HLOC 1LTJB 2J61A 1RF1B 1LWUB 1M1JC 2J1GA 1RF0B 1Z3SA 4JZCA 1RE3B 3HUSC 1FZDA 2OYIC 3GHGC 4NYTA 3FIBA 1N73C 3E1IC 4ZFGA 2J3UA 2Q9IB 1FZBC 1Z3UA 2H43B 1N86B 1FIBA 2JHIF 2WNPF 1FZFC 2Z4EC 4R9TA 1FIDA 2J3GA 2J3OA 2J64A 2FIBA 4M7HA 1RF1C 1LWUC 2XNXB 4EPUA 1FZCC 1FZEB 2J61B 3H32B 1RF0C 1RE4B 2HPCB 2HODB 1RE3C 4M7FA 4R9JA 1FZAB 1FZGB 2FFDB 2Q9IC 3BVHB 2OYHB 2JHMF 2H43C 2J5ZA 1LTJC 1N86C 1LT9B 4JYOX 2HLOB 2GY7A 2JHLF 2J3FD 2JHHC 2J2PA 2XNXC 1M1JB 2J0YA 1FZEC 3H32C 1RE4C 2HPCC 2J0GA 1JC9A 2HODC 1FZCB 1FZAC 1FZGC 2JHKF 2FFDC 3HUSB 2D39A 2OYIB 2J0HA 2J3FA 1N73B 3E1IB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZB B;  3BVH C;  2OYH C;  2J60 A;  1FZF B;  2Z4E B;  1LT9 C;  1FIC A;  2HLO C;  1LTJ B;  2J61 A;  1RF1 B;  1LWU B;  1M1J C;  2J1G A;  1RF0 B;  1Z3S A;  4JZC A;  1RE3 B;  3HUS C;  1FZD A;  2OYI C;  3GHG C;  4NYT A;  3FIB A;  1N73 C;  3E1I C;  4ZFG A;  2J3U A;  2Q9I B;  1FZB C;  1Z3U A;  2H43 B;  1N86 B;  1FIB A;  2JHI F;  2WNP F;  1FZF C;  2Z4E C;  4R9T A;  1FID A;  2J3G A;  2J3O A;  2J64 A;  2FIB A;  4M7H A;  1RF1 C;  1LWU C;  2XNX B;  4EPU A;  1FZC C;  1FZE B;  2J61 B;  3H32 B;  1RF0 C;  1RE4 B;  2HPC B;  2HOD B;  1RE3 C;  4M7F A;  4R9J A;  1FZA B;  1FZG B;  2FFD B;  2Q9I C;  3BVH B;  2OYH B;  2JHM F;  2H43 C;  2J5Z A;  1LTJ C;  1N86 C;  1LT9 B;  4JYO X;  2HLO B;  2GY7 A;  2JHL F;  2J3F D;  2JHH C;  2J2P A;  2XNX C;  1M1J B;  2J0Y A;  1FZE C;  3H32 C;  1RE4 C;  2HPC C;  2J0G A;  1JC9 A;  2HOD C;  1FZC B;  1FZA C;  1FZG C;  2JHK F;  2FFD C;  3HUS B;  2D39 A;  2OYI B;  2J0H A;  2J3F A;  1N73 B;  3E1I B; 
#chains in the Genus database with same CATH topology
 1FZB B;  3BVH C;  2OYH C;  2J60 A;  1FZF B;  2Z4E B;  1LT9 C;  1FIC A;  2HLO C;  1LTJ B;  2J61 A;  1RF1 B;  1LWU B;  1M1J C;  2J1G A;  1RF0 B;  1Z3S A;  4JZC A;  1RE3 B;  3HUS C;  1FZD A;  2OYI C;  3GHG C;  4NYT A;  3FIB A;  1N73 C;  3E1I C;  4ZFG A;  2J3U A;  2Q9I B;  1FZB C;  1Z3U A;  2H43 B;  1N86 B;  1FIB A;  2JHI F;  2WNP F;  1FZF C;  2Z4E C;  4R9T A;  1FID A;  2J3G A;  2J3O A;  2J64 A;  2FIB A;  4M7H A;  1RF1 C;  1LWU C;  2XNX B;  4EPU A;  1FZC C;  1FZE B;  2J61 B;  3H32 B;  1RF0 C;  1RE4 B;  2HPC B;  2HOD B;  1RE3 C;  4M7F A;  4R9J A;  1FZA B;  1FZG B;  2FFD B;  2Q9I C;  3BVH B;  2OYH B;  2JHM F;  2H43 C;  2J5Z A;  1LTJ C;  1N86 C;  1LT9 B;  4JYO X;  2HLO B;  2GY7 A;  2JHL F;  2J3F D;  2JHH C;  2J2P A;  2XNX C;  1M1J B;  2J0Y A;  1FZE C;  3H32 C;  1RE4 C;  2HPC C;  2J0G A;  1JC9 A;  2HOD C;  1FZC B;  1FZA C;  1FZG C;  2JHK F;  2FFD C;  3HUS B;  2D39 A;  2OYI B;  3GHG B;  2J0H A;  2J3F A;  1N73 B;  3E1I B; 
#chains in the Genus database with same CATH homology
 1FZB B;  3BVH C;  2OYH C;  2J60 A;  1FZF B;  2Z4E B;  1LT9 C;  1FIC A;  2HLO C;  1LTJ B;  2J61 A;  1RF1 B;  1LWU B;  1M1J C;  2J1G A;  1RF0 B;  1Z3S A;  4JZC A;  1RE3 B;  3HUS C;  1FZD A;  2OYI C;  3GHG C;  4NYT A;  3FIB A;  1N73 C;  3E1I C;  4ZFG A;  2J3U A;  2Q9I B;  1FZB C;  1Z3U A;  2H43 B;  1N86 B;  1FIB A;  2JHI F;  2WNP F;  1FZF C;  2Z4E C;  4R9T A;  1FID A;  2J3G A;  2J3O A;  2J64 A;  2FIB A;  4M7H A;  1RF1 C;  1LWU C;  2XNX B;  4EPU A;  1FZC C;  1FZE B;  2J61 B;  3H32 B;  1RF0 C;  1RE4 B;  2HPC B;  2HOD B;  1RE3 C;  4M7F A;  4R9J A;  1FZA B;  1FZG B;  2FFD B;  2Q9I C;  3BVH B;  2OYH B;  2JHM F;  2H43 C;  2J5Z A;  1LTJ C;  1N86 C;  1LT9 B;  4JYO X;  2HLO B;  2GY7 A;  2JHL F;  2J3F D;  2JHH C;  2J2P A;  2XNX C;  1M1J B;  2J0Y A;  1FZE C;  3H32 C;  1RE4 C;  2HPC C;  2J0G A;  1JC9 A;  2HOD C;  1FZC B;  1FZA C;  1FZG C;  2JHK F;  2FFD C;  3HUS B;  2D39 A;  2OYI B;  2J0H A;  2J3F A;  1N73 B;  3E1I B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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