2XNXC

Bc1 fragment of streptococcal m1 protein in complex with human fibrinogen
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
302
structure length
302
Chain Sequence
EEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
pubmed doi rcsb
molecule tags Cell adhesion
source organism Streptococcus pyogenes
molecule keywords FIBRINOGEN ALPHA CHAIN
total genus 75
structure length 302
sequence length 302
chains with identical sequence F, I, L
ec nomenclature
pdb deposition date 2010-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2xnxC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2xnxC02
3E1IC 2J0HA 3HUSB 2J3GA 2XNXC 1LT9C 1FZCC 1LWUB 1FZFC 2OYHB 2J3UA 2D39A 2JHLF 2Q9IC 2J0GA 2OYIC 2J3FD 3H32B 1FZEC 1FZAC 3BVHC 3E1IB 2H43C 2J60A 1FZBB 1LT9B 2HODC 1FZFB 1LTJC 2FFDB 4JYOX 1N73B 2Q9IB 2HLOC 1FZGC 2J0YA 1RF1C 1Z3SA 4JZCA 2Z4EC 2H43B 1M1JC 1RE4C 2J3FA 2JHKF 3FIBA 1LTJB 1RF0C 2JHIF 2XNXB 2JHHC 1RE3C 1FZCB 2GY7A 2HPCC 1N86C 2Z4EB 2OYIB 2OYHC 1FZEB 1FZAB 3BVHB 1FZDA 3H32C 2FIBA 1RF0B 2JHMF 4ZFGA 2WNPF 2HODB 2J1GA 4M7HA 2J2PA 1FICA 4NYTA 1N86B 1FZBC 2HPCB 3GHGC 1JC9A 1FIDA 2HLOB 2FFDC 3HUSC 1FZGB 1RF1B 2J61B 1FIBA 4M7FA 1LWUC 2J3OA 4R9JA 1M1JB 4EPUA 1N73C 1RE4B 2J5ZA 2J64A 2J61A 1Z3UA 1RE3B 4R9TA
chains in the Genus database with same CATH superfamily
3E1IC 2J0HA 3HUSB 2J3GA 2XNXC 1LT9C 1FZCC 1LWUB 1FZFC 2OYHB 2J3UA 2D39A 2JHLF 2Q9IC 2J0GA 2OYIC 2J3FD 3H32B 1FZEC 1FZAC 3BVHC 3E1IB 2H43C 2J60A 1FZBB 1LT9B 3GHGB 2HODC 1FZFB 1LTJC 2FFDB 4JYOX 1N73B 2Q9IB 2HLOC 1FZGC 2J0YA 1RF1C 1Z3SA 4JZCA 2Z4EC 2H43B 1M1JC 1RE4C 2J3FA 2JHKF 3FIBA 1LTJB 1RF0C 2JHIF 2XNXB 2JHHC 1RE3C 1FZCB 2GY7A 2HPCC 1N86C 2Z4EB 2OYIB 2OYHC 1FZEB 1FZAB 3BVHB 1FZDA 3H32C 2FIBA 1RF0B 2JHMF 4ZFGA 2WNPF 2HODB 2J1GA 4M7HA 2J2PA 1FICA 4NYTA 1N86B 1FZBC 2HPCB 3GHGC 1JC9A 1FIDA 2HLOB 2FFDC 3HUSC 1FZGB 1RF1B 2J61B 1FIBA 4M7FA 1LWUC 2J3OA 4R9JA 1M1JB 4EPUA 1N73C 1RE4B 2J5ZA 2J64A 2J61A 1Z3UA 1RE3B 4R9TA
chains in the Genus database with same CATH topology
3E1IC 2J0HA 3HUSB 2J3GA 2XNXC 1LT9C 1FZCC 1LWUB 1FZFC 2OYHB 2J3UA 2D39A 2JHLF 2Q9IC 2J0GA 2OYIC 2J3FD 3H32B 1FZEC 1FZAC 3BVHC 3E1IB 2H43C 2J60A 1FZBB 1LT9B 2HODC 1FZFB 1LTJC 2FFDB 4JYOX 1N73B 2Q9IB 2HLOC 1FZGC 2J0YA 1RF1C 1Z3SA 4JZCA 2Z4EC 2H43B 1M1JC 1RE4C 2J3FA 2JHKF 3FIBA 1LTJB 1RF0C 2JHIF 2XNXB 2JHHC 1RE3C 1FZCB 2GY7A 2HPCC 1N86C 2Z4EB 2OYIB 2OYHC 1FZEB 1FZAB 3BVHB 1FZDA 3H32C 2FIBA 1RF0B 2JHMF 4ZFGA 2WNPF 2HODB 2J1GA 4M7HA 2J2PA 1FICA 4NYTA 1N86B 1FZBC 2HPCB 3GHGC 1JC9A 1FIDA 2HLOB 2FFDC 3HUSC 1FZGB 1RF1B 2J61B 1FIBA 4M7FA 1LWUC 2J3OA 4R9JA 1M1JB 4EPUA 1N73C 1RE4B 2J5ZA 2J64A 2J61A 1Z3UA 1RE3B 4R9TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E1I C;  2J0H A;  3HUS B;  2J3G A;  2XNX C;  1LT9 C;  1FZC C;  1LWU B;  1FZF C;  2OYH B;  2J3U A;  2D39 A;  2JHL F;  2Q9I C;  2J0G A;  2OYI C;  2J3F D;  3H32 B;  1FZE C;  1FZA C;  3BVH C;  3E1I B;  2H43 C;  2J60 A;  1FZB B;  1LT9 B;  2HOD C;  1FZF B;  1LTJ C;  2FFD B;  4JYO X;  1N73 B;  2Q9I B;  2HLO C;  1FZG C;  2J0Y A;  1RF1 C;  1Z3S A;  4JZC A;  2Z4E C;  2H43 B;  1M1J C;  1RE4 C;  2J3F A;  2JHK F;  3FIB A;  1LTJ B;  1RF0 C;  2JHI F;  2XNX B;  2JHH C;  1RE3 C;  1FZC B;  2GY7 A;  2HPC C;  1N86 C;  2Z4E B;  2OYI B;  2OYH C;  1FZE B;  1FZA B;  3BVH B;  1FZD A;  3H32 C;  2FIB A;  1RF0 B;  2JHM F;  4ZFG A;  2WNP F;  2HOD B;  2J1G A;  4M7H A;  2J2P A;  1FIC A;  4NYT A;  1N86 B;  1FZB C;  2HPC B;  3GHG C;  1JC9 A;  1FID A;  2HLO B;  2FFD C;  3HUS C;  1FZG B;  1RF1 B;  2J61 B;  1FIB A;  4M7F A;  1LWU C;  2J3O A;  4R9J A;  1M1J B;  4EPU A;  1N73 C;  1RE4 B;  2J5Z A;  2J64 A;  2J61 A;  1Z3U A;  1RE3 B;  4R9T A; 
#chains in the Genus database with same CATH topology
 3E1I C;  2J0H A;  3HUS B;  2J3G A;  2XNX C;  1LT9 C;  1FZC C;  1LWU B;  1FZF C;  2OYH B;  2J3U A;  2D39 A;  2JHL F;  2Q9I C;  2J0G A;  2OYI C;  2J3F D;  3H32 B;  1FZE C;  1FZA C;  3BVH C;  3E1I B;  2H43 C;  2J60 A;  1FZB B;  1LT9 B;  3GHG B;  2HOD C;  1FZF B;  1LTJ C;  2FFD B;  4JYO X;  1N73 B;  2Q9I B;  2HLO C;  1FZG C;  2J0Y A;  1RF1 C;  1Z3S A;  4JZC A;  2Z4E C;  2H43 B;  1M1J C;  1RE4 C;  2J3F A;  2JHK F;  3FIB A;  1LTJ B;  1RF0 C;  2JHI F;  2XNX B;  2JHH C;  1RE3 C;  1FZC B;  2GY7 A;  2HPC C;  1N86 C;  2Z4E B;  2OYI B;  2OYH C;  1FZE B;  1FZA B;  3BVH B;  1FZD A;  3H32 C;  2FIB A;  1RF0 B;  2JHM F;  4ZFG A;  2WNP F;  2HOD B;  2J1G A;  4M7H A;  2J2P A;  1FIC A;  4NYT A;  1N86 B;  1FZB C;  2HPC B;  3GHG C;  1JC9 A;  1FID A;  2HLO B;  2FFD C;  3HUS C;  1FZG B;  1RF1 B;  2J61 B;  1FIB A;  4M7F A;  1LWU C;  2J3O A;  4R9J A;  1M1J B;  4EPU A;  1N73 C;  1RE4 B;  2J5Z A;  2J64 A;  2J61 A;  1Z3U A;  1RE3 B;  4R9T A; 
#chains in the Genus database with same CATH homology
 3E1I C;  2J0H A;  3HUS B;  2J3G A;  2XNX C;  1LT9 C;  1FZC C;  1LWU B;  1FZF C;  2OYH B;  2J3U A;  2D39 A;  2JHL F;  2Q9I C;  2J0G A;  2OYI C;  2J3F D;  3H32 B;  1FZE C;  1FZA C;  3BVH C;  3E1I B;  2H43 C;  2J60 A;  1FZB B;  1LT9 B;  2HOD C;  1FZF B;  1LTJ C;  2FFD B;  4JYO X;  1N73 B;  2Q9I B;  2HLO C;  1FZG C;  2J0Y A;  1RF1 C;  1Z3S A;  4JZC A;  2Z4E C;  2H43 B;  1M1J C;  1RE4 C;  2J3F A;  2JHK F;  3FIB A;  1LTJ B;  1RF0 C;  2JHI F;  2XNX B;  2JHH C;  1RE3 C;  1FZC B;  2GY7 A;  2HPC C;  1N86 C;  2Z4E B;  2OYI B;  2OYH C;  1FZE B;  1FZA B;  3BVH B;  1FZD A;  3H32 C;  2FIB A;  1RF0 B;  2JHM F;  4ZFG A;  2WNP F;  2HOD B;  2J1G A;  4M7H A;  2J2P A;  1FIC A;  4NYT A;  1N86 B;  1FZB C;  2HPC B;  3GHG C;  1JC9 A;  1FID A;  2HLO B;  2FFD C;  3HUS C;  1FZG B;  1RF1 B;  2J61 B;  1FIB A;  4M7F A;  1LWU C;  2J3O A;  4R9J A;  1M1J B;  4EPU A;  1N73 C;  1RE4 B;  2J5Z A;  2J64 A;  2J61 A;  1Z3U A;  1RE3 B;  4R9T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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