2Z4EB

Crystal structure of d-dimer from human fibrin complexed with gly-his-arg-pro-tyr-amide
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrinogen alpha chain
total genus 94
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 2007-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2z4eB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2z4eB02
3FIBA 1RE4B 1FZGC 2JHIF 2JHLF 2Z4EB 1RF0C 2J3FD 2J0HA 1N86C 2GY7A 1LWUC 4R9JA 1FZDA 1FZAC 4JYOX 2Q9IC 3BVHC 4ZFGA 1FIBA 2HPCC 2FFDB 2XNXB 1FZCC 2J3GA 3H32C 2J60A 2J0GA 2H43B 4M7HA 1LT9B 2J61A 2J5ZA 1RF1B 2HLOB 2J1GA 1FZBB 1N73C 1RE3C 1RE4C 2J3FA 3HUSB 2Z4EC 2JHHC 2FIBA 1FICA 1LTJB 4M7FA 2JHKF 2FFDC 2XNXC 3E1IC 2HODB 1LWUB 2OYHB 2H43C 1M1JB 2J3OA 1FZEB 2HLOC 2OYIB 1FZFB 2J61B 2J0YA 3BVHB 4R9TA 3HUSC 2J2PA 2J3UA 1Z3SA 1FZGB 4JZCA 1LTJC 1N73B 1RE3B 1RF0B 1N86B 1FZAB 4EPUA 1LT9C 2Q9IB 2HODC 2WNPF 3GHGC 4NYTA 2OYHC 1Z3UA 2HPCB 1RF1C 1M1JC 1FZCB 1FZEC 1FZBC 2D39A 3H32B 2OYIC 1JC9A 2J64A 1FZFC 3E1IB 1FIDA 2JHMF
chains in the Genus database with same CATH superfamily
3FIBA 1RE4B 1FZGC 2JHIF 2JHLF 2Z4EB 1RF0C 2J3FD 2J0HA 1N86C 2GY7A 1LWUC 4R9JA 1FZDA 1FZAC 4JYOX 2Q9IC 3BVHC 4ZFGA 1FIBA 2HPCC 2FFDB 2XNXB 1FZCC 2J3GA 3H32C 2J60A 2J0GA 2H43B 4M7HA 1LT9B 2J61A 2J5ZA 1RF1B 2HLOB 2J1GA 1FZBB 1N73C 1RE3C 1RE4C 2J3FA 3HUSB 2Z4EC 2JHHC 2FIBA 1FICA 1LTJB 4M7FA 2JHKF 2FFDC 2XNXC 3E1IC 2HODB 1LWUB 3GHGB 2OYHB 2H43C 1M1JB 2J3OA 1FZEB 2HLOC 2OYIB 1FZFB 2J61B 2J0YA 3BVHB 4R9TA 3HUSC 2J2PA 2J3UA 1Z3SA 1FZGB 4JZCA 1LTJC 1N73B 1RE3B 1RF0B 1N86B 1FZAB 4EPUA 1LT9C 2Q9IB 2HODC 2WNPF 3GHGC 4NYTA 2OYHC 1Z3UA 2HPCB 1RF1C 1M1JC 1FZCB 1FZEC 1FZBC 2D39A 3H32B 2OYIC 1JC9A 2J64A 1FZFC 3E1IB 1FIDA 2JHMF
chains in the Genus database with same CATH topology
3FIBA 1RE4B 1FZGC 2JHIF 2JHLF 2Z4EB 1RF0C 2J3FD 2J0HA 1N86C 2GY7A 1LWUC 4R9JA 1FZDA 1FZAC 4JYOX 2Q9IC 3BVHC 4ZFGA 1FIBA 2HPCC 2FFDB 2XNXB 1FZCC 2J3GA 3H32C 2J60A 2J0GA 2H43B 4M7HA 1LT9B 2J61A 2J5ZA 1RF1B 2HLOB 2J1GA 1FZBB 1N73C 1RE3C 1RE4C 2J3FA 3HUSB 2Z4EC 2JHHC 2FIBA 1FICA 1LTJB 4M7FA 2JHKF 2FFDC 2XNXC 3E1IC 2HODB 1LWUB 2OYHB 2H43C 1M1JB 2J3OA 1FZEB 2HLOC 2OYIB 1FZFB 2J61B 2J0YA 3BVHB 4R9TA 3HUSC 2J2PA 2J3UA 1Z3SA 1FZGB 4JZCA 1LTJC 1N73B 1RE3B 1RF0B 1N86B 1FZAB 4EPUA 1LT9C 2Q9IB 2HODC 2WNPF 3GHGC 4NYTA 2OYHC 1Z3UA 2HPCB 1RF1C 1M1JC 1FZCB 1FZEC 1FZBC 2D39A 3H32B 2OYIC 1JC9A 2J64A 1FZFC 3E1IB 1FIDA 2JHMF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FIB A;  1RE4 B;  1FZG C;  2JHI F;  2JHL F;  2Z4E B;  1RF0 C;  2J3F D;  2J0H A;  1N86 C;  2GY7 A;  1LWU C;  4R9J A;  1FZD A;  1FZA C;  4JYO X;  2Q9I C;  3BVH C;  4ZFG A;  1FIB A;  2HPC C;  2FFD B;  2XNX B;  1FZC C;  2J3G A;  3H32 C;  2J60 A;  2J0G A;  2H43 B;  4M7H A;  1LT9 B;  2J61 A;  2J5Z A;  1RF1 B;  2HLO B;  2J1G A;  1FZB B;  1N73 C;  1RE3 C;  1RE4 C;  2J3F A;  3HUS B;  2Z4E C;  2JHH C;  2FIB A;  1FIC A;  1LTJ B;  4M7F A;  2JHK F;  2FFD C;  2XNX C;  3E1I C;  2HOD B;  1LWU B;  2OYH B;  2H43 C;  1M1J B;  2J3O A;  1FZE B;  2HLO C;  2OYI B;  1FZF B;  2J61 B;  2J0Y A;  3BVH B;  4R9T A;  3HUS C;  2J2P A;  2J3U A;  1Z3S A;  1FZG B;  4JZC A;  1LTJ C;  1N73 B;  1RE3 B;  1RF0 B;  1N86 B;  1FZA B;  4EPU A;  1LT9 C;  2Q9I B;  2HOD C;  2WNP F;  3GHG C;  4NYT A;  2OYH C;  1Z3U A;  2HPC B;  1RF1 C;  1M1J C;  1FZC B;  1FZE C;  1FZB C;  2D39 A;  3H32 B;  2OYI C;  1JC9 A;  2J64 A;  1FZF C;  3E1I B;  1FID A;  2JHM F; 
#chains in the Genus database with same CATH topology
 3FIB A;  1RE4 B;  1FZG C;  2JHI F;  2JHL F;  2Z4E B;  1RF0 C;  2J3F D;  2J0H A;  1N86 C;  2GY7 A;  1LWU C;  4R9J A;  1FZD A;  1FZA C;  4JYO X;  2Q9I C;  3BVH C;  4ZFG A;  1FIB A;  2HPC C;  2FFD B;  2XNX B;  1FZC C;  2J3G A;  3H32 C;  2J60 A;  2J0G A;  2H43 B;  4M7H A;  1LT9 B;  2J61 A;  2J5Z A;  1RF1 B;  2HLO B;  2J1G A;  1FZB B;  1N73 C;  1RE3 C;  1RE4 C;  2J3F A;  3HUS B;  2Z4E C;  2JHH C;  2FIB A;  1FIC A;  1LTJ B;  4M7F A;  2JHK F;  2FFD C;  2XNX C;  3E1I C;  2HOD B;  1LWU B;  3GHG B;  2OYH B;  2H43 C;  1M1J B;  2J3O A;  1FZE B;  2HLO C;  2OYI B;  1FZF B;  2J61 B;  2J0Y A;  3BVH B;  4R9T A;  3HUS C;  2J2P A;  2J3U A;  1Z3S A;  1FZG B;  4JZC A;  1LTJ C;  1N73 B;  1RE3 B;  1RF0 B;  1N86 B;  1FZA B;  4EPU A;  1LT9 C;  2Q9I B;  2HOD C;  2WNP F;  3GHG C;  4NYT A;  2OYH C;  1Z3U A;  2HPC B;  1RF1 C;  1M1J C;  1FZC B;  1FZE C;  1FZB C;  2D39 A;  3H32 B;  2OYI C;  1JC9 A;  2J64 A;  1FZF C;  3E1I B;  1FID A;  2JHM F; 
#chains in the Genus database with same CATH homology
 3FIB A;  1RE4 B;  1FZG C;  2JHI F;  2JHL F;  2Z4E B;  1RF0 C;  2J3F D;  2J0H A;  1N86 C;  2GY7 A;  1LWU C;  4R9J A;  1FZD A;  1FZA C;  4JYO X;  2Q9I C;  3BVH C;  4ZFG A;  1FIB A;  2HPC C;  2FFD B;  2XNX B;  1FZC C;  2J3G A;  3H32 C;  2J60 A;  2J0G A;  2H43 B;  4M7H A;  1LT9 B;  2J61 A;  2J5Z A;  1RF1 B;  2HLO B;  2J1G A;  1FZB B;  1N73 C;  1RE3 C;  1RE4 C;  2J3F A;  3HUS B;  2Z4E C;  2JHH C;  2FIB A;  1FIC A;  1LTJ B;  4M7F A;  2JHK F;  2FFD C;  2XNX C;  3E1I C;  2HOD B;  1LWU B;  2OYH B;  2H43 C;  1M1J B;  2J3O A;  1FZE B;  2HLO C;  2OYI B;  1FZF B;  2J61 B;  2J0Y A;  3BVH B;  4R9T A;  3HUS C;  2J2P A;  2J3U A;  1Z3S A;  1FZG B;  4JZC A;  1LTJ C;  1N73 B;  1RE3 B;  1RF0 B;  1N86 B;  1FZA B;  4EPU A;  1LT9 C;  2Q9I B;  2HOD C;  2WNP F;  3GHG C;  4NYT A;  2OYH C;  1Z3U A;  2HPC B;  1RF1 C;  1M1J C;  1FZC B;  1FZE C;  1FZB C;  2D39 A;  3H32 B;  2OYI C;  1JC9 A;  2J64 A;  1FZF C;  3E1I B;  1FID A;  2JHM F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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