3BVHB

Crystal structure of recombinant gammad364a fibrinogen fragment d with the peptide ligand gly-pro-arg-pro-amide
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
298
structure length
298
Chain Sequence
IPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
source organism Homo sapiens
publication title Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.
pubmed doi rcsb
molecule keywords Fibrinogen alpha chain
total genus 93
structure length 298
sequence length 298
chains with identical sequence E
ec nomenclature
pdb deposition date 2008-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 3bvhB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 3bvhB02
1FZGB 3BVHC 1FZCC 2J3OA 3BVHB 1FZCB 2JHIF 2J60A 2J2PA 1FZEC 2OYHC 1FZEB 2OYHB 2JHHC 2J5ZA 4R9TA 1FICA 1Z3UA 2WNPF 1LT9C 1LT9B 1FZAC 2J0HA 2H43C 1FZAB 2H43B 1RF0C 2J1GA 1RF0B 1FZBC 1FZBB 1FZFC 1FZFB 4NYTA 4JYOX 1FIDA 2Z4EB 4M7HA 2J0YA 4JZCA 4EPUA 3E1IC 3E1IB 4ZFGA 4M7FA 1RE3C 1RE3B 3H32C 1RF1C 3H32B 1RF1B 2J3FA 2Q9IC 2OYIC 2Q9IB 2J3FD 1N73C 2OYIB 1FIBA 1N73B 2JHLF 2Z4EC 2HODC 2HODB 2J3UA 2XNXC 1LWUC 2XNXB 2FIBA 1JC9A 1LWUB 3HUSC 3HUSB 2HLOB 2JHKF 2J64A 2FFDC 2FFDB 1FZDA 3FIBA 1M1JC 1Z3SA 2HPCC 1M1JB 1RE4C 2HPCB 2J61A 2D39A 1RE4B 2J3GA 1LTJC 1LTJB 1N86C 3GHGC 2JHMF 1N86B 2GY7A 2J61B 4R9JA 2HLOC 1FZGC 2J0GA
chains in the Genus database with same CATH superfamily
1FZGB 3BVHC 1FZCC 2J3OA 3BVHB 1FZCB 2JHIF 2J60A 2J2PA 1FZEC 2OYHC 1FZEB 2OYHB 2JHHC 2J5ZA 4R9TA 1FICA 1Z3UA 2WNPF 1LT9C 1LT9B 1FZAC 2J0HA 2H43C 1FZAB 2H43B 1RF0C 2J1GA 1RF0B 1FZBC 1FZBB 1FZFC 1FZFB 4NYTA 4JYOX 1FIDA 2Z4EB 4M7HA 2J0YA 4JZCA 4EPUA 3E1IC 3E1IB 4ZFGA 4M7FA 1RE3C 1RE3B 3H32C 1RF1C 3H32B 1RF1B 2J3FA 2Q9IC 2OYIC 2Q9IB 2J3FD 1N73C 2OYIB 1FIBA 1N73B 2JHLF 2Z4EC 2HODC 3GHGB 2HODB 2J3UA 2XNXC 1LWUC 2XNXB 2FIBA 1JC9A 1LWUB 3HUSC 3HUSB 2HLOB 2JHKF 2J64A 2FFDC 2FFDB 1FZDA 3FIBA 1M1JC 1Z3SA 2HPCC 1M1JB 1RE4C 2HPCB 2J61A 2D39A 1RE4B 2J3GA 1LTJC 1LTJB 1N86C 3GHGC 2JHMF 1N86B 2GY7A 2J61B 4R9JA 2HLOC 1FZGC 2J0GA
chains in the Genus database with same CATH topology
1FZGB 3BVHC 1FZCC 2J3OA 3BVHB 1FZCB 2JHIF 2J60A 2J2PA 1FZEC 2OYHC 1FZEB 2OYHB 2JHHC 2J5ZA 4R9TA 1FICA 1Z3UA 2WNPF 1LT9C 1LT9B 1FZAC 2J0HA 2H43C 1FZAB 2H43B 1RF0C 2J1GA 1RF0B 1FZBC 1FZBB 1FZFC 1FZFB 4NYTA 4JYOX 1FIDA 2Z4EB 4M7HA 2J0YA 4JZCA 4EPUA 3E1IC 3E1IB 4ZFGA 4M7FA 1RE3C 1RE3B 3H32C 1RF1C 3H32B 1RF1B 2J3FA 2Q9IC 2OYIC 2Q9IB 2J3FD 1N73C 2OYIB 1FIBA 1N73B 2JHLF 2Z4EC 2HODC 2HODB 2J3UA 2XNXC 1LWUC 2XNXB 2FIBA 1JC9A 1LWUB 3HUSC 3HUSB 2HLOB 2JHKF 2J64A 2FFDC 2FFDB 1FZDA 3FIBA 1M1JC 1Z3SA 2HPCC 1M1JB 1RE4C 2HPCB 2J61A 2D39A 1RE4B 2J3GA 1LTJC 1LTJB 1N86C 3GHGC 2JHMF 1N86B 2GY7A 2J61B 4R9JA 2HLOC 1FZGC 2J0GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZG B;  3BVH C;  1FZC C;  2J3O A;  3BVH B;  1FZC B;  2JHI F;  2J60 A;  2J2P A;  1FZE C;  2OYH C;  1FZE B;  2OYH B;  2JHH C;  2J5Z A;  4R9T A;  1FIC A;  1Z3U A;  2WNP F;  1LT9 C;  1LT9 B;  1FZA C;  2J0H A;  2H43 C;  1FZA B;  2H43 B;  1RF0 C;  2J1G A;  1RF0 B;  1FZB C;  1FZB B;  1FZF C;  1FZF B;  4NYT A;  4JYO X;  1FID A;  2Z4E B;  4M7H A;  2J0Y A;  4JZC A;  4EPU A;  3E1I C;  3E1I B;  4ZFG A;  4M7F A;  1RE3 C;  1RE3 B;  3H32 C;  1RF1 C;  3H32 B;  1RF1 B;  2J3F A;  2Q9I C;  2OYI C;  2Q9I B;  2J3F D;  1N73 C;  2OYI B;  1FIB A;  1N73 B;  2JHL F;  2Z4E C;  2HOD C;  2HOD B;  2J3U A;  2XNX C;  1LWU C;  2XNX B;  2FIB A;  1JC9 A;  1LWU B;  3HUS C;  3HUS B;  2HLO B;  2JHK F;  2J64 A;  2FFD C;  2FFD B;  1FZD A;  3FIB A;  1M1J C;  1Z3S A;  2HPC C;  1M1J B;  1RE4 C;  2HPC B;  2J61 A;  2D39 A;  1RE4 B;  2J3G A;  1LTJ C;  1LTJ B;  1N86 C;  3GHG C;  2JHM F;  1N86 B;  2GY7 A;  2J61 B;  4R9J A;  2HLO C;  1FZG C;  2J0G A; 
#chains in the Genus database with same CATH topology
 1FZG B;  3BVH C;  1FZC C;  2J3O A;  3BVH B;  1FZC B;  2JHI F;  2J60 A;  2J2P A;  1FZE C;  2OYH C;  1FZE B;  2OYH B;  2JHH C;  2J5Z A;  4R9T A;  1FIC A;  1Z3U A;  2WNP F;  1LT9 C;  1LT9 B;  1FZA C;  2J0H A;  2H43 C;  1FZA B;  2H43 B;  1RF0 C;  2J1G A;  1RF0 B;  1FZB C;  1FZB B;  1FZF C;  1FZF B;  4NYT A;  4JYO X;  1FID A;  2Z4E B;  4M7H A;  2J0Y A;  4JZC A;  4EPU A;  3E1I C;  3E1I B;  4ZFG A;  4M7F A;  1RE3 C;  1RE3 B;  3H32 C;  1RF1 C;  3H32 B;  1RF1 B;  2J3F A;  2Q9I C;  2OYI C;  2Q9I B;  2J3F D;  1N73 C;  2OYI B;  1FIB A;  1N73 B;  2JHL F;  2Z4E C;  2HOD C;  3GHG B;  2HOD B;  2J3U A;  2XNX C;  1LWU C;  2XNX B;  2FIB A;  1JC9 A;  1LWU B;  3HUS C;  3HUS B;  2HLO B;  2JHK F;  2J64 A;  2FFD C;  2FFD B;  1FZD A;  3FIB A;  1M1J C;  1Z3S A;  2HPC C;  1M1J B;  1RE4 C;  2HPC B;  2J61 A;  2D39 A;  1RE4 B;  2J3G A;  1LTJ C;  1LTJ B;  1N86 C;  3GHG C;  2JHM F;  1N86 B;  2GY7 A;  2J61 B;  4R9J A;  2HLO C;  1FZG C;  2J0G A; 
#chains in the Genus database with same CATH homology
 1FZG B;  3BVH C;  1FZC C;  2J3O A;  3BVH B;  1FZC B;  2JHI F;  2J60 A;  2J2P A;  1FZE C;  2OYH C;  1FZE B;  2OYH B;  2JHH C;  2J5Z A;  4R9T A;  1FIC A;  1Z3U A;  2WNP F;  1LT9 C;  1LT9 B;  1FZA C;  2J0H A;  2H43 C;  1FZA B;  2H43 B;  1RF0 C;  2J1G A;  1RF0 B;  1FZB C;  1FZB B;  1FZF C;  1FZF B;  4NYT A;  4JYO X;  1FID A;  2Z4E B;  4M7H A;  2J0Y A;  4JZC A;  4EPU A;  3E1I C;  3E1I B;  4ZFG A;  4M7F A;  1RE3 C;  1RE3 B;  3H32 C;  1RF1 C;  3H32 B;  1RF1 B;  2J3F A;  2Q9I C;  2OYI C;  2Q9I B;  2J3F D;  1N73 C;  2OYI B;  1FIB A;  1N73 B;  2JHL F;  2Z4E C;  2HOD C;  2HOD B;  2J3U A;  2XNX C;  1LWU C;  2XNX B;  2FIB A;  1JC9 A;  1LWU B;  3HUS C;  3HUS B;  2HLO B;  2JHK F;  2J64 A;  2FFD C;  2FFD B;  1FZD A;  3FIB A;  1M1J C;  1Z3S A;  2HPC C;  1M1J B;  1RE4 C;  2HPC B;  2J61 A;  2D39 A;  1RE4 B;  2J3G A;  1LTJ C;  1LTJ B;  1N86 C;  3GHG C;  2JHM F;  1N86 B;  2GY7 A;  2J61 B;  4R9J A;  2HLO C;  1FZG C;  2J0G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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