3H32 | Genus

Total Genus 59

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	59
sequence length	301
structure length	301
Chain Sequence	EASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5cff05dc1936631c2ed1eb93/pdb.gz

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The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5cff05dc1936631c2ed1eb93/pdb.gz): 1063 ms

reading 301 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

301 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 25 ms

Adding embedded #jmolscript: select ({0:300});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Blood clotting
publication title	Two families of synthetic peptides that enhance fibrin turbidity and delay fibrinolysis by different mechanisms. pubmed doi rcsb
molecule keywords	Fibrinogen alpha chain
total genus	59
structure length	301
sequence length	301
chains with identical sequence	F
ec nomenclature
pdb deposition date	2009-04-15

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF00147	Fibrinogen_C	Fibrinogen beta and gamma chains, C-terminal globular domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.215.10	Alpha Beta	Alpha-Beta Complex	Gamma Fibrinogen; Chain A, domain 1	Gamma Fibrinogen, chain A, domain 1	3h32C01
4.10.530.10	Few Secondary Structures	Irregular	Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2	Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2	3h32C02

1FZEB 2Q9IB 2D39A 2XNXB 1N73C 1RE3C 1FZCB 1LWUC 4JZCA 4M7FA 1LT9C 3H32B 2J0YA 2HODC 2H43C 1M1JC 1N73B 1RE3B 1N86C 1LWUB 2OYIC 2J3OA 1LT9B 2HPCC 2HODB 3E1IC 3FIBA 1FZGC 4R9JA 2J3FA 1N86B 2J61A 1FZFC 2Z4EB 2FIBA 2J0GA 2OYHB 1RF0C 2HPCB 3E1IB 1FZGB 2J61B 2J60A 1FZFB 2J3FD 1FIBA 1FIDA 2WNPF 3GHGC 4M7HA 1FZDA 2J0HA 2J3GA 2H43B 4ZFGA 2JHKF 1M1JB 4R9TA 2HLOC 2FFDC 1RF1C 3BVHC 2OYIB 3HUSC 1Z3SA 1RE4C 2Q9IC 1LTJC 2XNXC 2JHIF 2FFDB 4JYOX 1RF1B 3BVHB 4EPUA 1FZBC 3HUSB 2J1GA 2JHLF 1RF0B 1RE4B 1LTJB 2GY7A 1FZAC 2J64A 1FICA 1Z3UA 2J2PA 1FZBB 2J3UA 1FZEC 2JHHC 1FZAB 4NYTA 1JC9A 2HLOB 2J5ZA 1FZCC 2Z4EC 2JHMF 2OYHC 3H32C
chains in the Genus database with same CATH superfamily

1FZEB 2Q9IB 2D39A 2XNXB 1N73C 1RE3C 1FZCB 1LWUC 4JZCA 4M7FA 1LT9C 3H32B 2J0YA 2HODC 2H43C 1M1JC 1N73B 1RE3B 1N86C 1LWUB 2OYIC 2J3OA 1LT9B 2HPCC 2HODB 3E1IC 3FIBA 1FZGC 4R9JA 2J3FA 1N86B 2J61A 1FZFC 2Z4EB 2FIBA 2J0GA 2OYHB 1RF0C 2HPCB 3E1IB 1FZGB 2J61B 2J60A 1FZFB 2J3FD 1FIBA 1FIDA 2WNPF 3GHGC 4M7HA 1FZDA 2J0HA 2J3GA 2H43B 4ZFGA 2JHKF 1M1JB 4R9TA 2HLOC 2FFDC 1RF1C 3BVHC 2OYIB 3HUSC 1Z3SA 3GHGB 1RE4C 2Q9IC 1LTJC 2XNXC 2JHIF 2FFDB 4JYOX 1RF1B 3BVHB 4EPUA 1FZBC 3HUSB 2J1GA 2JHLF 1RF0B 1RE4B 1LTJB 2GY7A 1FZAC 2J64A 1FICA 1Z3UA 2J2PA 1FZBB 2J3UA 1FZEC 2JHHC 1FZAB 4NYTA 1JC9A 2HLOB 2J5ZA 1FZCC 2Z4EC 2JHMF 2OYHC 3H32C
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1FZE B;  2Q9I B;  2D39 A;  2XNX B;  1N73 C;  1RE3 C;  1FZC B;  1LWU C;  4JZC A;  4M7F A;  1LT9 C;  3H32 B;  2J0Y A;  2HOD C;  2H43 C;  1M1J C;  1N73 B;  1RE3 B;  1N86 C;  1LWU B;  2OYI C;  2J3O A;  1LT9 B;  2HPC C;  2HOD B;  3E1I C;  3FIB A;  1FZG C;  4R9J A;  2J3F A;  1N86 B;  2J61 A;  1FZF C;  2Z4E B;  2FIB A;  2J0G A;  2OYH B;  1RF0 C;  2HPC B;  3E1I B;  1FZG B;  2J61 B;  2J60 A;  1FZF B;  2J3F D;  1FIB A;  1FID A;  2WNP F;  3GHG C;  4M7H A;  1FZD A;  2J0H A;  2J3G A;  2H43 B;  4ZFG A;  2JHK F;  1M1J B;  4R9T A;  2HLO C;  2FFD C;  1RF1 C;  3BVH C;  2OYI B;  3HUS C;  1Z3S A;  1RE4 C;  2Q9I C;  1LTJ C;  2XNX C;  2JHI F;  2FFD B;  4JYO X;  1RF1 B;  3BVH B;  4EPU A;  1FZB C;  3HUS B;  2J1G A;  2JHL F;  1RF0 B;  1RE4 B;  1LTJ B;  2GY7 A;  1FZA C;  2J64 A;  1FIC A;  1Z3U A;  2J2P A;  1FZB B;  2J3U A;  1FZE C;  2JHH C;  1FZA B;  4NYT A;  1JC9 A;  2HLO B;  2J5Z A;  1FZC C;  2Z4E C;  2JHM F;  2OYH C;  3H32 C; 
#chains in the Genus database with same CATH topology
 1FZE B;  2Q9I B;  2D39 A;  2XNX B;  1N73 C;  1RE3 C;  1FZC B;  1LWU C;  4JZC A;  4M7F A;  1LT9 C;  3H32 B;  2J0Y A;  2HOD C;  2H43 C;  1M1J C;  1N73 B;  1RE3 B;  1N86 C;  1LWU B;  2OYI C;  2J3O A;  1LT9 B;  2HPC C;  2HOD B;  3E1I C;  3FIB A;  1FZG C;  4R9J A;  2J3F A;  1N86 B;  2J61 A;  1FZF C;  2Z4E B;  2FIB A;  2J0G A;  2OYH B;  1RF0 C;  2HPC B;  3E1I B;  1FZG B;  2J61 B;  2J60 A;  1FZF B;  2J3F D;  1FIB A;  1FID A;  2WNP F;  3GHG C;  4M7H A;  1FZD A;  2J0H A;  2J3G A;  2H43 B;  4ZFG A;  2JHK F;  1M1J B;  4R9T A;  2HLO C;  2FFD C;  1RF1 C;  3BVH C;  2OYI B;  3HUS C;  1Z3S A;  3GHG B;  1RE4 C;  2Q9I C;  1LTJ C;  2XNX C;  2JHI F;  2FFD B;  4JYO X;  1RF1 B;  3BVH B;  4EPU A;  1FZB C;  3HUS B;  2J1G A;  2JHL F;  1RF0 B;  1RE4 B;  1LTJ B;  2GY7 A;  1FZA C;  2J64 A;  1FIC A;  1Z3U A;  2J2P A;  1FZB B;  2J3U A;  1FZE C;  2JHH C;  1FZA B;  4NYT A;  1JC9 A;  2HLO B;  2J5Z A;  1FZC C;  2Z4E C;  2JHM F;  2OYH C;  3H32 C; 
#chains in the Genus database with same CATH homology
 1FZE B;  2Q9I B;  2D39 A;  2XNX B;  1N73 C;  1RE3 C;  1FZC B;  1LWU C;  4JZC A;  4M7F A;  1LT9 C;  3H32 B;  2J0Y A;  2HOD C;  2H43 C;  1M1J C;  1N73 B;  1RE3 B;  1N86 C;  1LWU B;  2OYI C;  2J3O A;  1LT9 B;  2HPC C;  2HOD B;  3E1I C;  3FIB A;  1FZG C;  4R9J A;  2J3F A;  1N86 B;  2J61 A;  1FZF C;  2Z4E B;  2FIB A;  2J0G A;  2OYH B;  1RF0 C;  2HPC B;  3E1I B;  1FZG B;  2J61 B;  2J60 A;  1FZF B;  2J3F D;  1FIB A;  1FID A;  2WNP F;  3GHG C;  4M7H A;  1FZD A;  2J0H A;  2J3G A;  2H43 B;  4ZFG A;  2JHK F;  1M1J B;  4R9T A;  2HLO C;  2FFD C;  1RF1 C;  3BVH C;  2OYI B;  3HUS C;  1Z3S A;  1RE4 C;  2Q9I C;  1LTJ C;  2XNX C;  2JHI F;  2FFD B;  4JYO X;  1RF1 B;  3BVH B;  4EPU A;  1FZB C;  3HUS B;  2J1G A;  2JHL F;  1RF0 B;  1RE4 B;  1LTJ B;  2GY7 A;  1FZA C;  2J64 A;  1FIC A;  1Z3U A;  2J2P A;  1FZB B;  2J3U A;  1FZE C;  2JHH C;  1FZA B;  4NYT A;  1JC9 A;  2HLO B;  2J5Z A;  1FZC C;  2Z4E C;  2JHM F;  2OYH C;  3H32 C;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3H32C

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations