3BVHC

Crystal structure of recombinant gammad364a fibrinogen fragment d with the peptide ligand gly-pro-arg-pro-amide
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
293
structure length
293
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYANGIIWATWKTRWYSMKKTTMKIIPFNRLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords Fibrinogen alpha chain
total genus 88
structure length 293
sequence length 293
chains with identical sequence F
ec nomenclature
pdb deposition date 2008-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 3bvhC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 3bvhC02
3H32C 3HUSC 1FZCB 2JHKF 2OYHC 1FICA 1RF0C 2J61A 2HODC 2J2PA 2OYIC 1FZGB 1RE3B 1Z3UA 2GY7A 1N73B 2H43C 1FZBB 1LTJC 1FZFC 1FZEC 2J0YA 1M1JB 2J1GA 1LWUB 2FFDC 2Z4EC 3BVHB 2J3UA 2J3OA 3H32B 2J3FD 3FIBA 3HUSB 1Z3SA 1LT9C 1RF1C 2Q9IC 2J64A 2OYHB 4ZFGA 1RF0B 2HODB 4JZCA 2OYIB 4EPUA 2J60A 2J0GA 2H43B 1LTJB 1FZFB 1N86C 2JHHC 1RE4C 1FZEB 1JC9A 2HPCC 2J3FA 2J0HA 2D39A 2FFDB 2Z4EB 1FIBA 2FIBA 1FZAC 2HLOC 4R9JA 3E1IC 2XNXC 1FZDA 4M7FA 1LT9B 2J5ZA 1RF1B 2Q9IB 1FZCC 2JHLF 2JHMF 2WNPF 4M7HA 3GHGC 1FIDA 1FZGC 1RE3C 1N73C 1N86B 1FZBC 1RE4B 2J61B 4NYTA 2JHIF 2HPCB 1M1JC 1LWUC 4R9TA 1FZAB 2HLOB 4JYOX 2J3GA 3BVHC 3E1IB 2XNXB
chains in the Genus database with same CATH superfamily
3H32C 3HUSC 1FZCB 2JHKF 2OYHC 1FICA 1RF0C 2J61A 2HODC 2J2PA 3GHGB 2OYIC 1FZGB 1RE3B 1Z3UA 2GY7A 1N73B 2H43C 1FZBB 1LTJC 1FZFC 1FZEC 2J0YA 1M1JB 2J1GA 1LWUB 2FFDC 2Z4EC 3BVHB 2J3UA 2J3OA 3H32B 2J3FD 3FIBA 3HUSB 1Z3SA 1LT9C 1RF1C 2Q9IC 2J64A 2OYHB 4ZFGA 1RF0B 2HODB 4JZCA 2OYIB 4EPUA 2J60A 2J0GA 2H43B 1LTJB 1FZFB 1N86C 2JHHC 1RE4C 1FZEB 1JC9A 2HPCC 2J3FA 2J0HA 2D39A 2FFDB 2Z4EB 1FIBA 2FIBA 1FZAC 2HLOC 4R9JA 3E1IC 2XNXC 1FZDA 4M7FA 1LT9B 2J5ZA 1RF1B 2Q9IB 1FZCC 2JHLF 2JHMF 2WNPF 4M7HA 3GHGC 1FIDA 1FZGC 1RE3C 1N73C 1N86B 1FZBC 1RE4B 2J61B 4NYTA 2JHIF 2HPCB 1M1JC 1LWUC 4R9TA 1FZAB 2HLOB 4JYOX 2J3GA 3BVHC 3E1IB 2XNXB
chains in the Genus database with same CATH topology
3H32C 3HUSC 1FZCB 2JHKF 2OYHC 1FICA 1RF0C 2J61A 2HODC 2J2PA 2OYIC 1FZGB 1RE3B 1Z3UA 2GY7A 1N73B 2H43C 1FZBB 1LTJC 1FZFC 1FZEC 2J0YA 1M1JB 2J1GA 1LWUB 2FFDC 2Z4EC 3BVHB 2J3UA 2J3OA 3H32B 2J3FD 3FIBA 3HUSB 1Z3SA 1LT9C 1RF1C 2Q9IC 2J64A 2OYHB 4ZFGA 1RF0B 2HODB 4JZCA 2OYIB 4EPUA 2J60A 2J0GA 2H43B 1LTJB 1FZFB 1N86C 2JHHC 1RE4C 1FZEB 1JC9A 2HPCC 2J3FA 2J0HA 2D39A 2FFDB 2Z4EB 1FIBA 2FIBA 1FZAC 2HLOC 4R9JA 3E1IC 2XNXC 1FZDA 4M7FA 1LT9B 2J5ZA 1RF1B 2Q9IB 1FZCC 2JHLF 2JHMF 2WNPF 4M7HA 3GHGC 1FIDA 1FZGC 1RE3C 1N73C 1N86B 1FZBC 1RE4B 2J61B 4NYTA 2JHIF 2HPCB 1M1JC 1LWUC 4R9TA 1FZAB 2HLOB 4JYOX 2J3GA 3BVHC 3E1IB 2XNXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H32 C;  3HUS C;  1FZC B;  2JHK F;  2OYH C;  1FIC A;  1RF0 C;  2J61 A;  2HOD C;  2J2P A;  2OYI C;  1FZG B;  1RE3 B;  1Z3U A;  2GY7 A;  1N73 B;  2H43 C;  1FZB B;  1LTJ C;  1FZF C;  1FZE C;  2J0Y A;  1M1J B;  2J1G A;  1LWU B;  2FFD C;  2Z4E C;  3BVH B;  2J3U A;  2J3O A;  3H32 B;  2J3F D;  3FIB A;  3HUS B;  1Z3S A;  1LT9 C;  1RF1 C;  2Q9I C;  2J64 A;  2OYH B;  4ZFG A;  1RF0 B;  2HOD B;  4JZC A;  2OYI B;  4EPU A;  2J60 A;  2J0G A;  2H43 B;  1LTJ B;  1FZF B;  1N86 C;  2JHH C;  1RE4 C;  1FZE B;  1JC9 A;  2HPC C;  2J3F A;  2J0H A;  2D39 A;  2FFD B;  2Z4E B;  1FIB A;  2FIB A;  1FZA C;  2HLO C;  4R9J A;  3E1I C;  2XNX C;  1FZD A;  4M7F A;  1LT9 B;  2J5Z A;  1RF1 B;  2Q9I B;  1FZC C;  2JHL F;  2JHM F;  2WNP F;  4M7H A;  3GHG C;  1FID A;  1FZG C;  1RE3 C;  1N73 C;  1N86 B;  1FZB C;  1RE4 B;  2J61 B;  4NYT A;  2JHI F;  2HPC B;  1M1J C;  1LWU C;  4R9T A;  1FZA B;  2HLO B;  4JYO X;  2J3G A;  3BVH C;  3E1I B;  2XNX B; 
#chains in the Genus database with same CATH topology
 3H32 C;  3HUS C;  1FZC B;  2JHK F;  2OYH C;  1FIC A;  1RF0 C;  2J61 A;  2HOD C;  2J2P A;  3GHG B;  2OYI C;  1FZG B;  1RE3 B;  1Z3U A;  2GY7 A;  1N73 B;  2H43 C;  1FZB B;  1LTJ C;  1FZF C;  1FZE C;  2J0Y A;  1M1J B;  2J1G A;  1LWU B;  2FFD C;  2Z4E C;  3BVH B;  2J3U A;  2J3O A;  3H32 B;  2J3F D;  3FIB A;  3HUS B;  1Z3S A;  1LT9 C;  1RF1 C;  2Q9I C;  2J64 A;  2OYH B;  4ZFG A;  1RF0 B;  2HOD B;  4JZC A;  2OYI B;  4EPU A;  2J60 A;  2J0G A;  2H43 B;  1LTJ B;  1FZF B;  1N86 C;  2JHH C;  1RE4 C;  1FZE B;  1JC9 A;  2HPC C;  2J3F A;  2J0H A;  2D39 A;  2FFD B;  2Z4E B;  1FIB A;  2FIB A;  1FZA C;  2HLO C;  4R9J A;  3E1I C;  2XNX C;  1FZD A;  4M7F A;  1LT9 B;  2J5Z A;  1RF1 B;  2Q9I B;  1FZC C;  2JHL F;  2JHM F;  2WNP F;  4M7H A;  3GHG C;  1FID A;  1FZG C;  1RE3 C;  1N73 C;  1N86 B;  1FZB C;  1RE4 B;  2J61 B;  4NYT A;  2JHI F;  2HPC B;  1M1J C;  1LWU C;  4R9T A;  1FZA B;  2HLO B;  4JYO X;  2J3G A;  3BVH C;  3E1I B;  2XNX B; 
#chains in the Genus database with same CATH homology
 3H32 C;  3HUS C;  1FZC B;  2JHK F;  2OYH C;  1FIC A;  1RF0 C;  2J61 A;  2HOD C;  2J2P A;  2OYI C;  1FZG B;  1RE3 B;  1Z3U A;  2GY7 A;  1N73 B;  2H43 C;  1FZB B;  1LTJ C;  1FZF C;  1FZE C;  2J0Y A;  1M1J B;  2J1G A;  1LWU B;  2FFD C;  2Z4E C;  3BVH B;  2J3U A;  2J3O A;  3H32 B;  2J3F D;  3FIB A;  3HUS B;  1Z3S A;  1LT9 C;  1RF1 C;  2Q9I C;  2J64 A;  2OYH B;  4ZFG A;  1RF0 B;  2HOD B;  4JZC A;  2OYI B;  4EPU A;  2J60 A;  2J0G A;  2H43 B;  1LTJ B;  1FZF B;  1N86 C;  2JHH C;  1RE4 C;  1FZE B;  1JC9 A;  2HPC C;  2J3F A;  2J0H A;  2D39 A;  2FFD B;  2Z4E B;  1FIB A;  2FIB A;  1FZA C;  2HLO C;  4R9J A;  3E1I C;  2XNX C;  1FZD A;  4M7F A;  1LT9 B;  2J5Z A;  1RF1 B;  2Q9I B;  1FZC C;  2JHL F;  2JHM F;  2WNP F;  4M7H A;  3GHG C;  1FID A;  1FZG C;  1RE3 C;  1N73 C;  1N86 B;  1FZB C;  1RE4 B;  2J61 B;  4NYT A;  2JHI F;  2HPC B;  1M1J C;  1LWU C;  4R9T A;  1FZA B;  2HLO B;  4JYO X;  2J3G A;  3BVH C;  3E1I B;  2XNX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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