The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
70
|
sequence length |
220
|
structure length |
220
|
Chain Sequence |
QISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADFG
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.
pubmed doi rcsb |
| molecule tags |
Signaling protein/immune system
|
| source organism |
Homo sapiens
|
| molecule keywords |
Angiopoietin-2
|
| total genus |
70
|
| structure length |
220
|
| sequence length |
220
|
| ec nomenclature | |
| pdb deposition date | 2015-04-21 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00147 | Fibrinogen_C | Fibrinogen beta and gamma chains, C-terminal globular domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Complex | Gamma Fibrinogen; Chain A, domain 1 | Gamma Fibrinogen, chain A, domain 1 | ||
| Few Secondary Structures | Irregular | Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 | Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 |
#chains in the Genus database with same CATH superfamily 2GY7 A; 1N86 C; 2HPC B; 2OYI C; 2HPC C; 4NYT A; 1Z3S A; 2HOD B; 2HOD C; 1M1J B; 1LWU B; 2JHK F; 4JZC A; 1M1J C; 1LWU C; 1RE3 B; 2FIB A; 1RE4 B; 2OYH B; 2J3O A; 1FZG B; 1FIB A; 1RE3 C; 1LT9 B; 1JC9 A; 1RE4 C; 2OYH C; 1FZG C; 2Q9I B; 2J3G A; 2HLO B; 2H43 B; 2XNX B; 1FZB B; 2WNP F; 2JHI F; 2HLO C; 4R9T A; 2H43 C; 2XNX C; 1FID A; 1FZB C; 2J1G A; 2J61 A; 4R9J A; 3GHG C; 3BVH B; 4M7F A; 2J0G A; 3FIB A; 3BVH C; 2J61 B; 2J0H A; 3H32 B; 4JYO X; 3H32 C; 1FZC B; 4M7H A; 1LT9 C; 1FZC C; 1FZE B; 2Q9I C; 3HUS B; 2FFD B; 1FZE C; 1LTJ B; 2J3U A; 3HUS C; 1FZF B; 2FFD C; 2J3F A; 1LTJ C; 1FIC A; 2J60 A; 1FZF C; 1FZA B; 1N73 B; 1FZA C; 4ZFG A; 2JHM F; 2J0Y A; 2Z4E B; 1N73 C; 2JHL F; 2JHH C; 1RF1 B; 2Z4E C; 2J3F D; 1RF1 C; 1RF0 B; 2J2P A; 1Z3U A; 2D39 A; 3E1I B; 1RF0 C; 2J5Z A; 3E1I C; 1FZD A; 2J64 A; 1N86 B; 2OYI B; 4EPU A; #chains in the Genus database with same CATH topology 2GY7 A; 1N86 C; 2HPC B; 2OYI C; 2HPC C; 4NYT A; 1Z3S A; 2HOD B; 2HOD C; 1M1J B; 1LWU B; 2JHK F; 4JZC A; 1M1J C; 1LWU C; 1RE3 B; 2FIB A; 1RE4 B; 2OYH B; 2J3O A; 1FZG B; 1FIB A; 1RE3 C; 1LT9 B; 1JC9 A; 1RE4 C; 2OYH C; 1FZG C; 2Q9I B; 2J3G A; 2HLO B; 2H43 B; 2XNX B; 1FZB B; 2WNP F; 2JHI F; 2HLO C; 4R9T A; 3GHG B; 2H43 C; 2XNX C; 1FID A; 1FZB C; 2J1G A; 2J61 A; 4R9J A; 3GHG C; 3BVH B; 4M7F A; 2J0G A; 3FIB A; 3BVH C; 2J61 B; 2J0H A; 3H32 B; 4JYO X; 3H32 C; 1FZC B; 4M7H A; 1LT9 C; 1FZC C; 1FZE B; 2Q9I C; 3HUS B; 2FFD B; 1FZE C; 1LTJ B; 2J3U A; 3HUS C; 1FZF B; 2FFD C; 2J3F A; 1LTJ C; 1FIC A; 2J60 A; 1FZF C; 1FZA B; 1N73 B; 1FZA C; 4ZFG A; 2JHM F; 2J0Y A; 2Z4E B; 1N73 C; 2JHL F; 2JHH C; 1RF1 B; 2Z4E C; 2J3F D; 1RF1 C; 1RF0 B; 2J2P A; 1Z3U A; 2D39 A; 3E1I B; 1RF0 C; 2J5Z A; 3E1I C; 1FZD A; 2J64 A; 1N86 B; 2OYI B; 4EPU A; #chains in the Genus database with same CATH homology 2GY7 A; 1N86 C; 2HPC B; 2OYI C; 2HPC C; 4NYT A; 1Z3S A; 2HOD B; 2HOD C; 1M1J B; 1LWU B; 2JHK F; 4JZC A; 1M1J C; 1LWU C; 1RE3 B; 2FIB A; 1RE4 B; 2OYH B; 2J3O A; 1FZG B; 1FIB A; 1RE3 C; 1LT9 B; 1JC9 A; 1RE4 C; 2OYH C; 1FZG C; 2Q9I B; 2J3G A; 2HLO B; 2H43 B; 2XNX B; 1FZB B; 2WNP F; 2JHI F; 2HLO C; 4R9T A; 2H43 C; 2XNX C; 1FID A; 1FZB C; 2J1G A; 2J61 A; 4R9J A; 3GHG C; 3BVH B; 4M7F A; 2J0G A; 3FIB A; 3BVH C; 2J61 B; 2J0H A; 3H32 B; 4JYO X; 3H32 C; 1FZC B; 4M7H A; 1LT9 C; 1FZC C; 1FZE B; 2Q9I C; 3HUS B; 2FFD B; 1FZE C; 1LTJ B; 2J3U A; 3HUS C; 1FZF B; 2FFD C; 2J3F A; 1LTJ C; 1FIC A; 2J60 A; 1FZF C; 1FZA B; 1N73 B; 1FZA C; 4ZFG A; 2JHM F; 2J0Y A; 2Z4E B; 1N73 C; 2JHL F; 2JHH C; 1RF1 B; 2Z4E C; 2J3F D; 1RF1 C; 1RF0 B; 2J2P A; 1Z3U A; 2D39 A; 3E1I B; 1RF0 C; 2J5Z A; 3E1I C; 1FZD A; 2J64 A; 1N86 B; 2OYI B; 4EPU A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
