2HLOB

Crystal structure of fragment d-dimer from human fibrin complexed with gly-hydroxypro-arg-pro-amide
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Fibrin alpha chain
total genus 91
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 2006-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2hloB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2hloB02
2J61A 2JHLF 2HLOB 1RE3B 3BVHC 2XNXB 2GY7A 2Z4EC 1FZFC 3BVHB 1RF0C 1RF1C 1FIDA 2WNPF 1RF0B 1Z3UA 2Q9IC 4JYOX 1FZDA 2Q9IB 2OYHC 2OYHB 2J1GA 2FIBA 2J3OA 3E1IC 3HUSB 3H32C 2HLOC 1RE3C 2J3FA 3E1IB 2XNXC 3H32B 1M1JC 3FIBA 1JC9A 4R9JA 1M1JB 1FIBA 4JZCA 2FFDB 2J3GA 2D39A 3GHGC 1FZCB 1N86B 2J2PA 3HUSC 1FZGB 4NYTA 2J64A 4M7FA 1N73C 1LTJC 2J0HA 2JHIF 1N73B 2J0YA 1LTJB 1FZBC 1FZEC 1FZAB 2HPCC 2J61B 1FZBB 2FFDC 1LT9B 1FZEB 4EPUA 1FICA 2HPCB 2OYIB 1FZCC 4M7HA 4R9TA 1N86C 2HODC 1FZGC 2H43B 4ZFGA 2HODB 2J3FD 2J60A 1Z3SA 2JHKF 1FZAC 2J0GA 1FZFB 2Z4EB 1RF1B 1LT9C 2JHMF 1LWUC 2OYIC 2J3UA 1LWUB 1RE4C 2J5ZA 2JHHC 2H43C 1RE4B
chains in the Genus database with same CATH superfamily
2J61A 2JHLF 2HLOB 1RE3B 3BVHC 2XNXB 2GY7A 2Z4EC 1FZFC 3BVHB 1RF0C 1RF1C 1FIDA 2WNPF 1RF0B 1Z3UA 2Q9IC 4JYOX 1FZDA 2Q9IB 2OYHC 2OYHB 2J1GA 3GHGB 2FIBA 2J3OA 3E1IC 3HUSB 3H32C 2HLOC 1RE3C 2J3FA 3E1IB 2XNXC 3H32B 1M1JC 3FIBA 1JC9A 4R9JA 1M1JB 1FIBA 4JZCA 2FFDB 2J3GA 2D39A 3GHGC 1FZCB 1N86B 2J2PA 3HUSC 1FZGB 4NYTA 2J64A 4M7FA 1N73C 1LTJC 2J0HA 2JHIF 1N73B 2J0YA 1LTJB 1FZBC 1FZEC 1FZAB 2HPCC 2J61B 1FZBB 2FFDC 1LT9B 1FZEB 4EPUA 1FICA 2HPCB 2OYIB 1FZCC 4M7HA 4R9TA 1N86C 2HODC 1FZGC 2H43B 4ZFGA 2HODB 2J3FD 2J60A 1Z3SA 2JHKF 1FZAC 2J0GA 1FZFB 2Z4EB 1RF1B 1LT9C 2JHMF 1LWUC 2OYIC 2J3UA 1LWUB 1RE4C 2J5ZA 2JHHC 2H43C 1RE4B
chains in the Genus database with same CATH topology
2J61A 2JHLF 2HLOB 1RE3B 3BVHC 2XNXB 2GY7A 2Z4EC 1FZFC 3BVHB 1RF0C 1RF1C 1FIDA 2WNPF 1RF0B 1Z3UA 2Q9IC 4JYOX 1FZDA 2Q9IB 2OYHC 2OYHB 2J1GA 2FIBA 2J3OA 3E1IC 3HUSB 3H32C 2HLOC 1RE3C 2J3FA 3E1IB 2XNXC 3H32B 1M1JC 3FIBA 1JC9A 4R9JA 1M1JB 1FIBA 4JZCA 2FFDB 2J3GA 2D39A 3GHGC 1FZCB 1N86B 2J2PA 3HUSC 1FZGB 4NYTA 2J64A 4M7FA 1N73C 1LTJC 2J0HA 2JHIF 1N73B 2J0YA 1LTJB 1FZBC 1FZEC 1FZAB 2HPCC 2J61B 1FZBB 2FFDC 1LT9B 1FZEB 4EPUA 1FICA 2HPCB 2OYIB 1FZCC 4M7HA 4R9TA 1N86C 2HODC 1FZGC 2H43B 4ZFGA 2HODB 2J3FD 2J60A 1Z3SA 2JHKF 1FZAC 2J0GA 1FZFB 2Z4EB 1RF1B 1LT9C 2JHMF 1LWUC 2OYIC 2J3UA 1LWUB 1RE4C 2J5ZA 2JHHC 2H43C 1RE4B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J61 A;  2JHL F;  2HLO B;  1RE3 B;  3BVH C;  2XNX B;  2GY7 A;  2Z4E C;  1FZF C;  3BVH B;  1RF0 C;  1RF1 C;  1FID A;  2WNP F;  1RF0 B;  1Z3U A;  2Q9I C;  4JYO X;  1FZD A;  2Q9I B;  2OYH C;  2OYH B;  2J1G A;  2FIB A;  2J3O A;  3E1I C;  3HUS B;  3H32 C;  2HLO C;  1RE3 C;  2J3F A;  3E1I B;  2XNX C;  3H32 B;  1M1J C;  3FIB A;  1JC9 A;  4R9J A;  1M1J B;  1FIB A;  4JZC A;  2FFD B;  2J3G A;  2D39 A;  3GHG C;  1FZC B;  1N86 B;  2J2P A;  3HUS C;  1FZG B;  4NYT A;  2J64 A;  4M7F A;  1N73 C;  1LTJ C;  2J0H A;  2JHI F;  1N73 B;  2J0Y A;  1LTJ B;  1FZB C;  1FZE C;  1FZA B;  2HPC C;  2J61 B;  1FZB B;  2FFD C;  1LT9 B;  1FZE B;  4EPU A;  1FIC A;  2HPC B;  2OYI B;  1FZC C;  4M7H A;  4R9T A;  1N86 C;  2HOD C;  1FZG C;  2H43 B;  4ZFG A;  2HOD B;  2J3F D;  2J60 A;  1Z3S A;  2JHK F;  1FZA C;  2J0G A;  1FZF B;  2Z4E B;  1RF1 B;  1LT9 C;  2JHM F;  1LWU C;  2OYI C;  2J3U A;  1LWU B;  1RE4 C;  2J5Z A;  2JHH C;  2H43 C;  1RE4 B; 
#chains in the Genus database with same CATH topology
 2J61 A;  2JHL F;  2HLO B;  1RE3 B;  3BVH C;  2XNX B;  2GY7 A;  2Z4E C;  1FZF C;  3BVH B;  1RF0 C;  1RF1 C;  1FID A;  2WNP F;  1RF0 B;  1Z3U A;  2Q9I C;  4JYO X;  1FZD A;  2Q9I B;  2OYH C;  2OYH B;  2J1G A;  3GHG B;  2FIB A;  2J3O A;  3E1I C;  3HUS B;  3H32 C;  2HLO C;  1RE3 C;  2J3F A;  3E1I B;  2XNX C;  3H32 B;  1M1J C;  3FIB A;  1JC9 A;  4R9J A;  1M1J B;  1FIB A;  4JZC A;  2FFD B;  2J3G A;  2D39 A;  3GHG C;  1FZC B;  1N86 B;  2J2P A;  3HUS C;  1FZG B;  4NYT A;  2J64 A;  4M7F A;  1N73 C;  1LTJ C;  2J0H A;  2JHI F;  1N73 B;  2J0Y A;  1LTJ B;  1FZB C;  1FZE C;  1FZA B;  2HPC C;  2J61 B;  1FZB B;  2FFD C;  1LT9 B;  1FZE B;  4EPU A;  1FIC A;  2HPC B;  2OYI B;  1FZC C;  4M7H A;  4R9T A;  1N86 C;  2HOD C;  1FZG C;  2H43 B;  4ZFG A;  2HOD B;  2J3F D;  2J60 A;  1Z3S A;  2JHK F;  1FZA C;  2J0G A;  1FZF B;  2Z4E B;  1RF1 B;  1LT9 C;  2JHM F;  1LWU C;  2OYI C;  2J3U A;  1LWU B;  1RE4 C;  2J5Z A;  2JHH C;  2H43 C;  1RE4 B; 
#chains in the Genus database with same CATH homology
 2J61 A;  2JHL F;  2HLO B;  1RE3 B;  3BVH C;  2XNX B;  2GY7 A;  2Z4E C;  1FZF C;  3BVH B;  1RF0 C;  1RF1 C;  1FID A;  2WNP F;  1RF0 B;  1Z3U A;  2Q9I C;  4JYO X;  1FZD A;  2Q9I B;  2OYH C;  2OYH B;  2J1G A;  2FIB A;  2J3O A;  3E1I C;  3HUS B;  3H32 C;  2HLO C;  1RE3 C;  2J3F A;  3E1I B;  2XNX C;  3H32 B;  1M1J C;  3FIB A;  1JC9 A;  4R9J A;  1M1J B;  1FIB A;  4JZC A;  2FFD B;  2J3G A;  2D39 A;  3GHG C;  1FZC B;  1N86 B;  2J2P A;  3HUS C;  1FZG B;  4NYT A;  2J64 A;  4M7F A;  1N73 C;  1LTJ C;  2J0H A;  2JHI F;  1N73 B;  2J0Y A;  1LTJ B;  1FZB C;  1FZE C;  1FZA B;  2HPC C;  2J61 B;  1FZB B;  2FFD C;  1LT9 B;  1FZE B;  4EPU A;  1FIC A;  2HPC B;  2OYI B;  1FZC C;  4M7H A;  4R9T A;  1N86 C;  2HOD C;  1FZG C;  2H43 B;  4ZFG A;  2HOD B;  2J3F D;  2J60 A;  1Z3S A;  2JHK F;  1FZA C;  2J0G A;  1FZF B;  2Z4E B;  1RF1 B;  1LT9 C;  2JHM F;  1LWU C;  2OYI C;  2J3U A;  1LWU B;  1RE4 C;  2J5Z A;  2JHH C;  2H43 C;  1RE4 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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