1PIV4

Binding of the antiviral drug win51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYKDSASNAASKQDYSQDPSKFTEPLKDVLIKTAPALN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
pubmed doi rcsb
molecule tags Virus
source organism Poliovirus type 3 (strains p3/leon/37 and p3/leon 12a[1]b)
molecule keywords POLIOVIRUS TYPE 3 (SUBUNIT VP1)
total genus 4
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1995-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1piv400
4Q4W4 1BEV4 3JD74 2RMU4 1HRV4 2RM24 1VRH4 1MQTD 1RUE4 2HWC4 1AR74 2RS54 4RHV4 1ASJ4 1H8TD 1RUG4 1VBD4 1RHI4 2PLV4 4GB34 1RMU4 1VBB4 1RUH4 1EAH4 3J8F4 1PVC4 1VBE4 4PDWD 1AR64 1EV14 2RR14 2RS14 1R084 1COV4 1Z7S4 1VBC4 1NCQD 1HRI4 1OOPD 1PIV4 1RVF4 1VBA4 4Q4V4 1D4M4 4Q4Y4 1RUI4 1RUD4 1PO24 1R094 4Q4X4 1RUF4 2R074 2R044 1AR84 1POV0 1RUC4 1RUJ4 1HXS4 1NA1D 2X5ID 2RS34 1PO14 3JBG4 2R064 1AL24 2HWB4 1AR94 1K5MD
chains in the Genus database with same CATH superfamily
3ABVA 1KF6A 1BEV4 4YTMA 2RM24 2WDVA 2PW9A 2WU5A 1AR74 1ASJ4 1RUG4 1VBD4 1RHI4 3AEBA 3VR9A 1XI1A 1XHZA 1RVF4 1ZOYA 1D4M4 1PO24 1RUF4 1ZP0A 3VRAA 1PO14 1YQ3A 3JBG4 2PYLA 1KFYA 1AR94 3GQHA 1K5MD 4Q4W4 3AEEA 3JD74 1HRV4 2PYJA 1VRH4 2B76A 1MQTD 3AEAA 3CIRA 3AE8A 3AE5A 2PY5A 1RUH4 3AECA 2RS14 1COV4 3VRBA 1Z7S4 3FI7A 2R7FA 4YSYA 1VBA4 3AE6A 4Q4Y4 1RUI4 2WP9A 3SUCA 4KX6A 1YQ4A 2R044 1L0VA 2X5ID 5C3JA 1AL24 3VR8A 2WS3A 3AE4A 1RUE4 4YT0A 4RHV4 1H8TD 4YTPA 4GB34 4YXDA 3GQKA 1PVC4 1EV14 1VBC4 2H88A 1OOPD 1NEKA 1XHXA 2H89A 1R094 2FBWA 3AE3A 1AR84 1RUC4 1HXS4 1NA1D 2RS34 3AE2A 2HWB4 1PIV4 4YSZA 2R064 2EX3A 3AE9A 2RMU4 2PZSA 1NENA 2HWC4 2RS54 3AEFA 2WU2A 3P4QA 2PLV4 2WDRA 3P4PA 4YSXA 1RMU4 3P4SA 1VBB4 3J8F4 1EAH4 4PDWD 1VBE4 1AR64 2RR14 2WDQA 3SFDA 1R084 3AE1A 1NCQD 1HRI4 2WQYA 3P4RA 4Q4V4 3AEGA 3AEDA 5C2TA 1RUD4 3AE7A 4Q4X4 2R074 1POV0 1RUJ4 4YTNA 3SFEA 2ACZA
chains in the Genus database with same CATH topology
4Q4W4 1BEV4 3JD74 2RMU4 1HRV4 2RM24 1VRH4 1MQTD 1RUE4 2HWC4 1AR74 2RS54 4RHV4 1ASJ4 1H8TD 1RUG4 1VBD4 1RHI4 2PLV4 4GB34 1RMU4 1VBB4 1RUH4 1EAH4 3J8F4 1PVC4 1VBE4 4PDWD 1AR64 1EV14 2RR14 2RS14 1R084 1COV4 1Z7S4 1VBC4 1NCQD 1HRI4 1OOPD 1PIV4 1RVF4 1VBA4 4Q4V4 1D4M4 4Q4Y4 1RUI4 1RUD4 1PO24 1R094 4Q4X4 1RUF4 2R074 2R044 1AR84 1POV0 1RUC4 1RUJ4 1HXS4 1NA1D 2X5ID 2RS34 1PO14 3JBG4 2R064 1AL24 2HWB4 1AR94 1K5MD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q4W 4;  1BEV 4;  3JD7 4;  2RMU 4;  1HRV 4;  2RM2 4;  1VRH 4;  1MQT D;  1RUE 4;  2HWC 4;  1AR7 4;  2RS5 4;  4RHV 4;  1ASJ 4;  1H8T D;  1RUG 4;  1VBD 4;  1RHI 4;  2PLV 4;  4GB3 4;  1RMU 4;  1VBB 4;  1RUH 4;  1EAH 4;  3J8F 4;  1PVC 4;  1VBE 4;  4PDW D;  1AR6 4;  1EV1 4;  2RR1 4;  2RS1 4;  1R08 4;  1COV 4;  1Z7S 4;  1VBC 4;  1NCQ D;  1HRI 4;  1OOP D;  1PIV 4;  1RVF 4;  1VBA 4;  4Q4V 4;  1D4M 4;  4Q4Y 4;  1RUI 4;  1RUD 4;  1PO2 4;  1R09 4;  4Q4X 4;  1RUF 4;  2R07 4;  2R04 4;  1AR8 4;  1POV 0;  1RUC 4;  1RUJ 4;  1HXS 4;  1NA1 D;  2X5I D;  2RS3 4;  1PO1 4;  3JBG 4;  2R06 4;  1AL2 4;  2HWB 4;  1AR9 4;  1K5M D; 
#chains in the Genus database with same CATH topology
 3ABV A;  1KF6 A;  1BEV 4;  4YTM A;  2RM2 4;  2WDV A;  2PW9 A;  2WU5 A;  1AR7 4;  1ASJ 4;  1RUG 4;  1VBD 4;  1RHI 4;  3AEB A;  3VR9 A;  1XI1 A;  1XHZ A;  1RVF 4;  1ZOY A;  1D4M 4;  1PO2 4;  1RUF 4;  1ZP0 A;  3VRA A;  1PO1 4;  1YQ3 A;  3JBG 4;  2PYL A;  1KFY A;  1AR9 4;  3GQH A;  1K5M D;  4Q4W 4;  3AEE A;  3JD7 4;  1HRV 4;  2PYJ A;  1VRH 4;  2B76 A;  1MQT D;  3AEA A;  3CIR A;  3AE8 A;  3AE5 A;  2PY5 A;  1RUH 4;  3AEC A;  2RS1 4;  1COV 4;  3VRB A;  1Z7S 4;  3FI7 A;  2R7F A;  4YSY A;  1VBA 4;  3AE6 A;  4Q4Y 4;  1RUI 4;  2WP9 A;  3SUC A;  4KX6 A;  1YQ4 A;  2R04 4;  1L0V A;  2X5I D;  5C3J A;  1AL2 4;  3VR8 A;  2WS3 A;  3AE4 A;  1RUE 4;  4YT0 A;  4RHV 4;  1H8T D;  4YTP A;  4GB3 4;  4YXD A;  3GQK A;  1PVC 4;  1EV1 4;  1VBC 4;  2H88 A;  1OOP D;  1NEK A;  1XHX A;  2H89 A;  1R09 4;  2FBW A;  3AE3 A;  1AR8 4;  1RUC 4;  1HXS 4;  1NA1 D;  2RS3 4;  3AE2 A;  2HWB 4;  1PIV 4;  4YSZ A;  2R06 4;  2EX3 A;  3AE9 A;  2RMU 4;  2PZS A;  1NEN A;  2HWC 4;  2RS5 4;  3AEF A;  2WU2 A;  3P4Q A;  2PLV 4;  2WDR A;  3P4P A;  4YSX A;  1RMU 4;  3P4S A;  1VBB 4;  3J8F 4;  1EAH 4;  4PDW D;  1VBE 4;  1AR6 4;  2RR1 4;  2WDQ A;  3SFD A;  1R08 4;  3AE1 A;  1NCQ D;  1HRI 4;  2WQY A;  3P4R A;  4Q4V 4;  3AEG A;  3AED A;  5C2T A;  1RUD 4;  3AE7 A;  4Q4X 4;  2R07 4;  1POV 0;  1RUJ 4;  4YTN A;  3SFE A;  2ACZ A; 
#chains in the Genus database with same CATH homology
 4Q4W 4;  1BEV 4;  3JD7 4;  2RMU 4;  1HRV 4;  2RM2 4;  1VRH 4;  1MQT D;  1RUE 4;  2HWC 4;  1AR7 4;  2RS5 4;  4RHV 4;  1ASJ 4;  1H8T D;  1RUG 4;  1VBD 4;  1RHI 4;  2PLV 4;  4GB3 4;  1RMU 4;  1VBB 4;  1RUH 4;  1EAH 4;  3J8F 4;  1PVC 4;  1VBE 4;  4PDW D;  1AR6 4;  1EV1 4;  2RR1 4;  2RS1 4;  1R08 4;  1COV 4;  1Z7S 4;  1VBC 4;  1NCQ D;  1HRI 4;  1OOP D;  1PIV 4;  1RVF 4;  1VBA 4;  4Q4V 4;  1D4M 4;  4Q4Y 4;  1RUI 4;  1RUD 4;  1PO2 4;  1R09 4;  4Q4X 4;  1RUF 4;  2R07 4;  2R04 4;  1AR8 4;  1POV 0;  1RUC 4;  1RUJ 4;  1HXS 4;  1NA1 D;  2X5I D;  2RS3 4;  1PO1 4;  3JBG 4;  2R06 4;  1AL2 4;  2HWB 4;  1AR9 4;  1K5M D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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