1PIV4

Binding of the antiviral drug win51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYKDSASNAASKQDYSQDPSKFTEPLKDVLIKTAPALN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Virus
source organism Poliovirus type 3 (strains p3/leon/37 and p3/leon 12a[1]b)
publication title Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
pubmed doi rcsb
molecule keywords POLIOVIRUS TYPE 3 (SUBUNIT VP1)
total genus 4
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1995-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1piv400
1VBD4 2HWC4 2RS14 1RVF4 1PO14 1R094 1MQTD 1PO24 1RUF4 1EAH4 1AR64 2R044 3J8F4 2RR14 1BEV4 1HRV4 1RUC4 1H8TD 3JD74 1ASJ4 1HRI4 1NCQD 2PLV4 3JBG4 2HWB4 1R084 1AL24 2RMU4 2X5ID 2RM24 1D4M4 1VBE4 4GB34 1AR94 4PDWD 2R064 4Q4V4 1VBA4 1RUJ4 4RHV4 2R074 1AR74 1OOPD 1EV14 1RMU4 1RUH4 1K5MD 1COV4 1PVC4 1HXS4 1RUE4 1RUI4 1RUG4 4Q4W4 1PIV4 1VRH4 1POV0 1AR84 1VBB4 1RHI4 1VBC4 2RS34 2RS54 1NA1D 4Q4Y4 1Z7S4 4Q4X4 1RUD4
chains in the Genus database with same CATH superfamily
2HWC4 2PW9A 2RS14 1RVF4 4YXDA 2R044 1XHZA 2RR14 1XHXA 3JD74 3SUCA 2PLV4 3CIRA 1L0VA 3VRAA 3GQHA 2RMU4 4GB34 2R064 1NEKA 1RUJ4 3GQKA 4YSXA 2ACZA 3FI7A 1EV14 1RUI4 2WP9A 4Q4W4 1PIV4 1VBB4 3P4PA 4Q4Y4 3AE9A 3AEDA 1R094 2WU2A 1RUF4 1HRV4 3AEGA 1HRI4 1NCQD 2HWB4 1NENA 3VR9A 1YQ3A 4YTNA 1VBE4 3P4SA 4Q4V4 1VBA4 3AE3A 2R074 3AE2A 1RMU4 3AE5A 1COV4 1PVC4 2WQYA 1ZP0A 2RS34 4YSYA 1NA1D 1VBD4 1MQTD 2R7FA 2PYJA 5C2TA 1AR64 3J8F4 3AECA 1RUC4 3AEEA 3JBG4 3SFDA 2WDVA 1AL24 2X5ID 2RM24 1XI1A 4PDWD 1AR94 2PYLA 3SFEA 2FBWA 2WS3A 2PZSA 4KX6A 1OOPD 2WDRA 1RUH4 1HXS4 1RUE4 3AE6A 3VR8A 1VRH4 3AE4A 1VBC4 3AE7A 3AEBA 4YTPA 1Z7S4 1RUD4 2WU5A 1PO14 1PO24 4YTMA 1KFYA 1EAH4 1ZOYA 3AE8A 1BEV4 4YSZA 1YQ4A 3AEFA 1H8TD 5C3JA 3AE1A 2WDQA 1ASJ4 3P4QA 2PY5A 1R084 2H89A 3P4RA 3ABVA 3AEAA 1D4M4 4RHV4 2B76A 1AR74 3VRBA 1K5MD 2EX3A 1RUG4 1POV0 1AR84 2RS54 1RHI4 2H88A 1KF6A 4YT0A 4Q4X4
chains in the Genus database with same CATH topology
1VBD4 2HWC4 2RS14 1RVF4 1PO14 1R094 1MQTD 1PO24 1RUF4 1EAH4 1AR64 2R044 3J8F4 2RR14 1BEV4 1HRV4 1RUC4 1H8TD 3JD74 1ASJ4 1HRI4 1NCQD 2PLV4 3JBG4 2HWB4 1R084 1AL24 2RMU4 2X5ID 2RM24 1D4M4 1VBE4 4GB34 1AR94 4PDWD 2R064 4Q4V4 1VBA4 1RUJ4 4RHV4 2R074 1AR74 1OOPD 1EV14 1RMU4 1RUH4 1K5MD 1COV4 1PVC4 1HXS4 1RUE4 1RUI4 1RUG4 4Q4W4 1PIV4 1VRH4 1POV0 1AR84 1VBB4 1RHI4 1VBC4 2RS34 2RS54 1NA1D 4Q4Y4 1Z7S4 4Q4X4 1RUD4
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VBD 4;  2HWC 4;  2RS1 4;  1RVF 4;  1PO1 4;  1R09 4;  1MQT D;  1PO2 4;  1RUF 4;  1EAH 4;  1AR6 4;  2R04 4;  3J8F 4;  2RR1 4;  1BEV 4;  1HRV 4;  1RUC 4;  1H8T D;  3JD7 4;  1ASJ 4;  1HRI 4;  1NCQ D;  2PLV 4;  3JBG 4;  2HWB 4;  1R08 4;  1AL2 4;  2RMU 4;  2X5I D;  2RM2 4;  1D4M 4;  1VBE 4;  4GB3 4;  1AR9 4;  4PDW D;  2R06 4;  4Q4V 4;  1VBA 4;  1RUJ 4;  4RHV 4;  2R07 4;  1AR7 4;  1OOP D;  1EV1 4;  1RMU 4;  1RUH 4;  1K5M D;  1COV 4;  1PVC 4;  1HXS 4;  1RUE 4;  1RUI 4;  1RUG 4;  4Q4W 4;  1PIV 4;  1VRH 4;  1POV 0;  1AR8 4;  1VBB 4;  1RHI 4;  1VBC 4;  2RS3 4;  2RS5 4;  1NA1 D;  4Q4Y 4;  1Z7S 4;  4Q4X 4;  1RUD 4; 
#chains in the Genus database with same CATH topology
 2HWC 4;  2PW9 A;  2RS1 4;  1RVF 4;  4YXD A;  2R04 4;  1XHZ A;  2RR1 4;  1XHX A;  3JD7 4;  3SUC A;  2PLV 4;  3CIR A;  1L0V A;  3VRA A;  3GQH A;  2RMU 4;  4GB3 4;  2R06 4;  1NEK A;  1RUJ 4;  3GQK A;  4YSX A;  2ACZ A;  3FI7 A;  1EV1 4;  1RUI 4;  2WP9 A;  4Q4W 4;  1PIV 4;  1VBB 4;  3P4P A;  4Q4Y 4;  3AE9 A;  3AED A;  1R09 4;  2WU2 A;  1RUF 4;  1HRV 4;  3AEG A;  1HRI 4;  1NCQ D;  2HWB 4;  1NEN A;  3VR9 A;  1YQ3 A;  4YTN A;  1VBE 4;  3P4S A;  4Q4V 4;  1VBA 4;  3AE3 A;  2R07 4;  3AE2 A;  1RMU 4;  3AE5 A;  1COV 4;  1PVC 4;  2WQY A;  1ZP0 A;  2RS3 4;  4YSY A;  1NA1 D;  1VBD 4;  1MQT D;  2R7F A;  2PYJ A;  5C2T A;  1AR6 4;  3J8F 4;  3AEC A;  1RUC 4;  3AEE A;  3JBG 4;  3SFD A;  2WDV A;  1AL2 4;  2X5I D;  2RM2 4;  1XI1 A;  4PDW D;  1AR9 4;  2PYL A;  3SFE A;  2FBW A;  2WS3 A;  2PZS A;  4KX6 A;  1OOP D;  2WDR A;  1RUH 4;  1HXS 4;  1RUE 4;  3AE6 A;  3VR8 A;  1VRH 4;  3AE4 A;  1VBC 4;  3AE7 A;  3AEB A;  4YTP A;  1Z7S 4;  1RUD 4;  2WU5 A;  1PO1 4;  1PO2 4;  4YTM A;  1KFY A;  1EAH 4;  1ZOY A;  3AE8 A;  1BEV 4;  4YSZ A;  1YQ4 A;  3AEF A;  1H8T D;  5C3J A;  3AE1 A;  2WDQ A;  1ASJ 4;  3P4Q A;  2PY5 A;  1R08 4;  2H89 A;  3P4R A;  3ABV A;  3AEA A;  1D4M 4;  4RHV 4;  2B76 A;  1AR7 4;  3VRB A;  1K5M D;  2EX3 A;  1RUG 4;  1POV 0;  1AR8 4;  2RS5 4;  1RHI 4;  2H88 A;  1KF6 A;  4YT0 A;  4Q4X 4; 
#chains in the Genus database with same CATH homology
 1VBD 4;  2HWC 4;  2RS1 4;  1RVF 4;  1PO1 4;  1R09 4;  1MQT D;  1PO2 4;  1RUF 4;  1EAH 4;  1AR6 4;  2R04 4;  3J8F 4;  2RR1 4;  1BEV 4;  1HRV 4;  1RUC 4;  1H8T D;  3JD7 4;  1ASJ 4;  1HRI 4;  1NCQ D;  2PLV 4;  3JBG 4;  2HWB 4;  1R08 4;  1AL2 4;  2RMU 4;  2X5I D;  2RM2 4;  1D4M 4;  1VBE 4;  4GB3 4;  1AR9 4;  4PDW D;  2R06 4;  4Q4V 4;  1VBA 4;  1RUJ 4;  4RHV 4;  2R07 4;  1AR7 4;  1OOP D;  1EV1 4;  1RMU 4;  1RUH 4;  1K5M D;  1COV 4;  1PVC 4;  1HXS 4;  1RUE 4;  1RUI 4;  1RUG 4;  4Q4W 4;  1PIV 4;  1VRH 4;  1POV 0;  1AR8 4;  1VBB 4;  1RHI 4;  1VBC 4;  2RS3 4;  2RS5 4;  1NA1 D;  4Q4Y 4;  1Z7S 4;  4Q4X 4;  1RUD 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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