1PIV4

Binding of the antiviral drug win51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYKDSASNAASKQDYSQDPSKFTEPLKDVLIKTAPALN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
pubmed doi rcsb
molecule tags Virus
source organism Poliovirus type 3 (strains p3/leon/37 and p3/leon 12a[1]b)
molecule keywords POLIOVIRUS TYPE 3 (SUBUNIT VP1)
total genus 4
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1995-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1piv400
2RS34 1VBC4 1AL24 1HRV4 1OOPD 1POV0 2X5ID 1RUC4 1VBA4 1VBD4 1RUH4 3JBG4 4Q4Y4 1K5MD 1NA1D 1RUD4 3JD74 2PLV4 2RS14 3J8F4 1ASJ4 4GB34 2RMU4 2HWC4 1PO24 2RM24 1AR64 1VRH4 2RR14 4RHV4 1PVC4 1AR84 1RUE4 1PO14 1VBE4 1RUJ4 4PDWD 1VBB4 1RUG4 1H8TD 2RS54 1R094 2R064 1PIV4 2R074 1AR94 1R084 1RVF4 2R044 1HRI4 1NCQD 4Q4X4 1HXS4 1Z7S4 1RUI4 1BEV4 1COV4 1D4M4 1RMU4 1AR74 1RHI4 1EV14 1RUF4 1MQTD 4Q4V4 2HWB4 4Q4W4 1EAH4
chains in the Genus database with same CATH superfamily
4YTPA 1AL24 1POV0 1RUC4 2WP9A 4Q4Y4 1NA1D 3JD74 2WU2A 2RS14 3AEBA 3AEAA 2FBWA 2H89A 2RMU4 3SUCA 2RM24 3P4RA 1YQ3A 2PY5A 3SFDA 1PVC4 3CIRA 2WDQA 3GQKA 3VR8A 1NEKA 1RUJ4 4PDWD 2WDVA 2R064 1AR94 1R084 1RVF4 3P4SA 1BEV4 1NENA 1RMU4 4YXDA 2B76A 1RHI4 1RUF4 4Q4W4 1EAH4 2X5ID 1VBD4 1RUH4 1K5MD 2ACZA 2H88A 3J8F4 3AEDA 2WDRA 2HWC4 1PO24 1AR64 1VRH4 3AE8A 3VR9A 3AECA 4YTNA 1H8TD 1R094 2R074 1XHZA 1KFYA 1HRI4 1HXS4 3GQHA 1COV4 1D4M4 1AR74 4YSZA 3P4PA 3AE4A 1XHXA 1ZOYA 1VBC4 1HRV4 3JBG4 4YTMA 1RUD4 4YSXA 1KF6A 2R7FA 2PYLA 3AE3A 3AE6A 2PZSA 1AR84 1RUE4 4KX6A 1PO14 1ZP0A 1L0VA 1RUG4 2R044 5C2TA 1RUI4 3FI7A 1EV14 1MQTD 5C3JA 4Q4V4 2HWB4 2WU5A 4GB34 2RS34 3SFEA 3AEEA 1OOPD 1VBA4 2PLV4 3P4QA 1ASJ4 3VRAA 1XI1A 3ABVA 2RR14 4RHV4 3AE5A 3AEGA 4YT0A 1VBE4 2PW9A 1YQ4A 1VBB4 2RS54 3VRBA 1PIV4 2WS3A 2PYJA 3AE1A 3AE9A 1NCQD 4YSYA 4Q4X4 1Z7S4 2EX3A 2WQYA 3AE7A 3AEFA 3AE2A
chains in the Genus database with same CATH topology
2RS34 1VBC4 1AL24 1HRV4 1OOPD 1POV0 2X5ID 1RUC4 1VBA4 1VBD4 1RUH4 3JBG4 4Q4Y4 1K5MD 1NA1D 1RUD4 3JD74 2PLV4 2RS14 3J8F4 1ASJ4 4GB34 2RMU4 2HWC4 1PO24 2RM24 1AR64 1VRH4 2RR14 4RHV4 1PVC4 1AR84 1RUE4 1PO14 1VBE4 1RUJ4 4PDWD 1VBB4 1RUG4 1H8TD 2RS54 1R094 2R064 1PIV4 2R074 1AR94 1R084 1RVF4 2R044 1HRI4 1NCQD 4Q4X4 1HXS4 1Z7S4 1RUI4 1BEV4 1COV4 1D4M4 1RMU4 1AR74 1RHI4 1EV14 1RUF4 1MQTD 4Q4V4 2HWB4 4Q4W4 1EAH4
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RS3 4;  1VBC 4;  1AL2 4;  1HRV 4;  1OOP D;  1POV 0;  2X5I D;  1RUC 4;  1VBA 4;  1VBD 4;  1RUH 4;  3JBG 4;  4Q4Y 4;  1K5M D;  1NA1 D;  1RUD 4;  3JD7 4;  2PLV 4;  2RS1 4;  3J8F 4;  1ASJ 4;  4GB3 4;  2RMU 4;  2HWC 4;  1PO2 4;  2RM2 4;  1AR6 4;  1VRH 4;  2RR1 4;  4RHV 4;  1PVC 4;  1AR8 4;  1RUE 4;  1PO1 4;  1VBE 4;  1RUJ 4;  4PDW D;  1VBB 4;  1RUG 4;  1H8T D;  2RS5 4;  1R09 4;  2R06 4;  1PIV 4;  2R07 4;  1AR9 4;  1R08 4;  1RVF 4;  2R04 4;  1HRI 4;  1NCQ D;  4Q4X 4;  1HXS 4;  1Z7S 4;  1RUI 4;  1BEV 4;  1COV 4;  1D4M 4;  1RMU 4;  1AR7 4;  1RHI 4;  1EV1 4;  1RUF 4;  1MQT D;  4Q4V 4;  2HWB 4;  4Q4W 4;  1EAH 4; 
#chains in the Genus database with same CATH topology
 4YTP A;  1AL2 4;  1POV 0;  1RUC 4;  2WP9 A;  4Q4Y 4;  1NA1 D;  3JD7 4;  2WU2 A;  2RS1 4;  3AEB A;  3AEA A;  2FBW A;  2H89 A;  2RMU 4;  3SUC A;  2RM2 4;  3P4R A;  1YQ3 A;  2PY5 A;  3SFD A;  1PVC 4;  3CIR A;  2WDQ A;  3GQK A;  3VR8 A;  1NEK A;  1RUJ 4;  4PDW D;  2WDV A;  2R06 4;  1AR9 4;  1R08 4;  1RVF 4;  3P4S A;  1BEV 4;  1NEN A;  1RMU 4;  4YXD A;  2B76 A;  1RHI 4;  1RUF 4;  4Q4W 4;  1EAH 4;  2X5I D;  1VBD 4;  1RUH 4;  1K5M D;  2ACZ A;  2H88 A;  3J8F 4;  3AED A;  2WDR A;  2HWC 4;  1PO2 4;  1AR6 4;  1VRH 4;  3AE8 A;  3VR9 A;  3AEC A;  4YTN A;  1H8T D;  1R09 4;  2R07 4;  1XHZ A;  1KFY A;  1HRI 4;  1HXS 4;  3GQH A;  1COV 4;  1D4M 4;  1AR7 4;  4YSZ A;  3P4P A;  3AE4 A;  1XHX A;  1ZOY A;  1VBC 4;  1HRV 4;  3JBG 4;  4YTM A;  1RUD 4;  4YSX A;  1KF6 A;  2R7F A;  2PYL A;  3AE3 A;  3AE6 A;  2PZS A;  1AR8 4;  1RUE 4;  4KX6 A;  1PO1 4;  1ZP0 A;  1L0V A;  1RUG 4;  2R04 4;  5C2T A;  1RUI 4;  3FI7 A;  1EV1 4;  1MQT D;  5C3J A;  4Q4V 4;  2HWB 4;  2WU5 A;  4GB3 4;  2RS3 4;  3SFE A;  3AEE A;  1OOP D;  1VBA 4;  2PLV 4;  3P4Q A;  1ASJ 4;  3VRA A;  1XI1 A;  3ABV A;  2RR1 4;  4RHV 4;  3AE5 A;  3AEG A;  4YT0 A;  1VBE 4;  2PW9 A;  1YQ4 A;  1VBB 4;  2RS5 4;  3VRB A;  1PIV 4;  2WS3 A;  2PYJ A;  3AE1 A;  3AE9 A;  1NCQ D;  4YSY A;  4Q4X 4;  1Z7S 4;  2EX3 A;  2WQY A;  3AE7 A;  3AEF A;  3AE2 A; 
#chains in the Genus database with same CATH homology
 2RS3 4;  1VBC 4;  1AL2 4;  1HRV 4;  1OOP D;  1POV 0;  2X5I D;  1RUC 4;  1VBA 4;  1VBD 4;  1RUH 4;  3JBG 4;  4Q4Y 4;  1K5M D;  1NA1 D;  1RUD 4;  3JD7 4;  2PLV 4;  2RS1 4;  3J8F 4;  1ASJ 4;  4GB3 4;  2RMU 4;  2HWC 4;  1PO2 4;  2RM2 4;  1AR6 4;  1VRH 4;  2RR1 4;  4RHV 4;  1PVC 4;  1AR8 4;  1RUE 4;  1PO1 4;  1VBE 4;  1RUJ 4;  4PDW D;  1VBB 4;  1RUG 4;  1H8T D;  2RS5 4;  1R09 4;  2R06 4;  1PIV 4;  2R07 4;  1AR9 4;  1R08 4;  1RVF 4;  2R04 4;  1HRI 4;  1NCQ D;  4Q4X 4;  1HXS 4;  1Z7S 4;  1RUI 4;  1BEV 4;  1COV 4;  1D4M 4;  1RMU 4;  1AR7 4;  1RHI 4;  1EV1 4;  1RUF 4;  1MQT D;  4Q4V 4;  2HWB 4;  4Q4W 4;  1EAH 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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