1PO14

Poliovirus (type 1, mahoney) in complex with r80633, an inhibitor of viral replication
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYRDSASNAASKQDFSQDPSKFTEPIKDVLIKTAPMLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
pubmed doi rcsb
molecule tags Virus
molecule keywords POLIOVIRUS TYPE 1 MAHONEY
total genus 4
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1997-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1po1400
1RUI4 2HWB4 1COV4 1R094 4Q4V4 1VBE4 1RUF4 1AR74 1OOPD 1PIV4 4GB34 4PDWD 1AR94 1AR64 1H8TD 1RVF4 1PO14 1AL24 1RMU4 1VBA4 1ASJ4 1R084 2R074 1VBD4 1EAH4 1BEV4 1PVC4 1RUJ4 1D4M4 1MQTD 1RUD4 2RS34 4Q4W4 1RUG4 2HWC4 2RR14 2RS54 3JD74 1NA1D 1HXS4 1VBC4 1RUE4 2RMU4 3J8F4 2RM24 1NCQD 1VBB4 4RHV4 1PO24 2R064 2X5ID 1K5MD 1Z7S4 2RS14 1EV14 1RHI4 4Q4Y4 1AR84 1HRV4 4Q4X4 1VRH4 2R044 3JBG4 1RUH4 1POV0 1HRI4 2PLV4 1RUC4
chains in the Genus database with same CATH superfamily
1AR74 2WDRA 1AL24 1KFYA 2PYJA 4YTMA 4YSXA 2R074 3AE3A 1YQ3A 1D4M4 2PYLA 4YXDA 3AEGA 4Q4W4 3JD74 1NA1D 3AE8A 3J8F4 3VR8A 4YSZA 1VBB4 3AE2A 1NENA 2X5ID 1K5MD 1EV14 4Q4Y4 5C2TA 3GQHA 1XHXA 2R044 3P4RA 2PLV4 1RUI4 2HWB4 2ACZA 1R094 4Q4V4 3P4SA 3VR9A 1VBE4 4GB34 4YSYA 4PDWD 1AR64 1H8TD 2EX3A 2R7FA 1XI1A 1ASJ4 1VBD4 1EAH4 3AEFA 3P4QA 1BEV4 1PVC4 3AE7A 1MQTD 2RR14 2RS54 3AE6A 1HXS4 3AEBA 4YTNA 3AE9A 2RM24 1NCQD 3AEAA 3VRBA 2FBWA 2WU5A 4YTPA 3GQKA 1HRV4 4Q4X4 4KX6A 1RUH4 3P4PA 2WU2A 1YQ4A 1COV4 1ZOYA 1AR94 1VBA4 1R084 1XHZA 3AECA 1RUJ4 1RUD4 2RS34 1RUG4 3SUCA 1VBC4 1RUE4 2RMU4 1PO24 1Z7S4 1L0VA 3VRAA 3AEDA 2WP9A 3AE4A 1AR84 3SFEA 2WS3A 1ZP0A 1RUC4 2WDVA 2B76A 3AEEA 1RUF4 1PIV4 1OOPD 3ABVA 3AE5A 1RVF4 1KF6A 1PO14 4YT0A 2PW9A 1RMU4 3CIRA 2WDQA 3FI7A 3SFDA 5C3JA 2HWC4 2H88A 1NEKA 2PY5A 4RHV4 2R064 2WQYA 2PZSA 2RS14 1RHI4 2H89A 3JBG4 1VRH4 1POV0 1HRI4 3AE1A
chains in the Genus database with same CATH topology
1RUI4 2HWB4 1COV4 1R094 4Q4V4 1VBE4 1RUF4 1AR74 1OOPD 1PIV4 4GB34 4PDWD 1AR94 1AR64 1H8TD 1RVF4 1PO14 1AL24 1RMU4 1VBA4 1ASJ4 1R084 2R074 1VBD4 1EAH4 1BEV4 1PVC4 1RUJ4 1D4M4 1MQTD 1RUD4 2RS34 4Q4W4 1RUG4 2HWC4 2RR14 2RS54 3JD74 1NA1D 1HXS4 1VBC4 1RUE4 2RMU4 3J8F4 2RM24 1NCQD 1VBB4 4RHV4 1PO24 2R064 2X5ID 1K5MD 1Z7S4 2RS14 1EV14 1RHI4 4Q4Y4 1AR84 1HRV4 4Q4X4 1VRH4 2R044 3JBG4 1RUH4 1POV0 1HRI4 2PLV4 1RUC4
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RUI 4;  2HWB 4;  1COV 4;  1R09 4;  4Q4V 4;  1VBE 4;  1RUF 4;  1AR7 4;  1OOP D;  1PIV 4;  4GB3 4;  4PDW D;  1AR9 4;  1AR6 4;  1H8T D;  1RVF 4;  1PO1 4;  1AL2 4;  1RMU 4;  1VBA 4;  1ASJ 4;  1R08 4;  2R07 4;  1VBD 4;  1EAH 4;  1BEV 4;  1PVC 4;  1RUJ 4;  1D4M 4;  1MQT D;  1RUD 4;  2RS3 4;  4Q4W 4;  1RUG 4;  2HWC 4;  2RR1 4;  2RS5 4;  3JD7 4;  1NA1 D;  1HXS 4;  1VBC 4;  1RUE 4;  2RMU 4;  3J8F 4;  2RM2 4;  1NCQ D;  1VBB 4;  4RHV 4;  1PO2 4;  2R06 4;  2X5I D;  1K5M D;  1Z7S 4;  2RS1 4;  1EV1 4;  1RHI 4;  4Q4Y 4;  1AR8 4;  1HRV 4;  4Q4X 4;  1VRH 4;  2R04 4;  3JBG 4;  1RUH 4;  1POV 0;  1HRI 4;  2PLV 4;  1RUC 4; 
#chains in the Genus database with same CATH topology
 1AR7 4;  2WDR A;  1AL2 4;  1KFY A;  2PYJ A;  4YTM A;  4YSX A;  2R07 4;  3AE3 A;  1YQ3 A;  1D4M 4;  2PYL A;  4YXD A;  3AEG A;  4Q4W 4;  3JD7 4;  1NA1 D;  3AE8 A;  3J8F 4;  3VR8 A;  4YSZ A;  1VBB 4;  3AE2 A;  1NEN A;  2X5I D;  1K5M D;  1EV1 4;  4Q4Y 4;  5C2T A;  3GQH A;  1XHX A;  2R04 4;  3P4R A;  2PLV 4;  1RUI 4;  2HWB 4;  2ACZ A;  1R09 4;  4Q4V 4;  3P4S A;  3VR9 A;  1VBE 4;  4GB3 4;  4YSY A;  4PDW D;  1AR6 4;  1H8T D;  2EX3 A;  2R7F A;  1XI1 A;  1ASJ 4;  1VBD 4;  1EAH 4;  3AEF A;  3P4Q A;  1BEV 4;  1PVC 4;  3AE7 A;  1MQT D;  2RR1 4;  2RS5 4;  3AE6 A;  1HXS 4;  3AEB A;  4YTN A;  3AE9 A;  2RM2 4;  1NCQ D;  3AEA A;  3VRB A;  2FBW A;  2WU5 A;  4YTP A;  3GQK A;  1HRV 4;  4Q4X 4;  4KX6 A;  1RUH 4;  3P4P A;  2WU2 A;  1YQ4 A;  1COV 4;  1ZOY A;  1AR9 4;  1VBA 4;  1R08 4;  1XHZ A;  3AEC A;  1RUJ 4;  1RUD 4;  2RS3 4;  1RUG 4;  3SUC A;  1VBC 4;  1RUE 4;  2RMU 4;  1PO2 4;  1Z7S 4;  1L0V A;  3VRA A;  3AED A;  2WP9 A;  3AE4 A;  1AR8 4;  3SFE A;  2WS3 A;  1ZP0 A;  1RUC 4;  2WDV A;  2B76 A;  3AEE A;  1RUF 4;  1PIV 4;  1OOP D;  3ABV A;  3AE5 A;  1RVF 4;  1KF6 A;  1PO1 4;  4YT0 A;  2PW9 A;  1RMU 4;  3CIR A;  2WDQ A;  3FI7 A;  3SFD A;  5C3J A;  2HWC 4;  2H88 A;  1NEK A;  2PY5 A;  4RHV 4;  2R06 4;  2WQY A;  2PZS A;  2RS1 4;  1RHI 4;  2H89 A;  3JBG 4;  1VRH 4;  1POV 0;  1HRI 4;  3AE1 A; 
#chains in the Genus database with same CATH homology
 1RUI 4;  2HWB 4;  1COV 4;  1R09 4;  4Q4V 4;  1VBE 4;  1RUF 4;  1AR7 4;  1OOP D;  1PIV 4;  4GB3 4;  4PDW D;  1AR9 4;  1AR6 4;  1H8T D;  1RVF 4;  1PO1 4;  1AL2 4;  1RMU 4;  1VBA 4;  1ASJ 4;  1R08 4;  2R07 4;  1VBD 4;  1EAH 4;  1BEV 4;  1PVC 4;  1RUJ 4;  1D4M 4;  1MQT D;  1RUD 4;  2RS3 4;  4Q4W 4;  1RUG 4;  2HWC 4;  2RR1 4;  2RS5 4;  3JD7 4;  1NA1 D;  1HXS 4;  1VBC 4;  1RUE 4;  2RMU 4;  3J8F 4;  2RM2 4;  1NCQ D;  1VBB 4;  4RHV 4;  1PO2 4;  2R06 4;  2X5I D;  1K5M D;  1Z7S 4;  2RS1 4;  1EV1 4;  1RHI 4;  4Q4Y 4;  1AR8 4;  1HRV 4;  4Q4X 4;  1VRH 4;  2R04 4;  3JBG 4;  1RUH 4;  1POV 0;  1HRI 4;  2PLV 4;  1RUC 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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