1PO14

Poliovirus (type 1, mahoney) in complex with r80633, an inhibitor of viral replication
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYRDSASNAASKQDFSQDPSKFTEPIKDVLIKTAPMLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Virus
publication title Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
pubmed doi rcsb
molecule keywords POLIOVIRUS TYPE 1 MAHONEY
total genus 4
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1997-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1po1400
1NCQD 1H8TD 1RHI4 1K5MD 3J8F4 2HWC4 1PIV4 1VBC4 1D4M4 1OOPD 1RMU4 1RUH4 1ASJ4 1Z7S4 1RUD4 2R074 1HRV4 4Q4V4 1RUI4 2RS34 4RHV4 1PVC4 1PO14 2R064 1MQTD 1AR64 1BEV4 1EAH4 1AR84 1EV14 1VRH4 2PLV4 1R084 2X5ID 4Q4X4 1PO24 1RUG4 4Q4W4 1RUJ4 2RMU4 1HRI4 3JBG4 4Q4Y4 1RUE4 2RS54 1COV4 3JD74 1VBE4 1RVF4 2RR14 1VBD4 1AL24 1AR94 1HXS4 1NA1D 2HWB4 2R044 2RS14 2RM24 4PDWD 1RUF4 1POV0 1VBA4 1VBB4 1AR74 1R094 4GB34 1RUC4
chains in the Genus database with same CATH superfamily
3J8F4 2PW9A 3AE8A 1OOPD 1RUD4 3VR9A 2R074 3AEAA 3AE2A 2RS34 1PVC4 1PO14 2R064 1MQTD 1BEV4 3AECA 2WU2A 4YTNA 2PYJA 1RUG4 1RUJ4 3VRAA 5C2TA 3AEFA 3P4RA 3GQKA 3JD74 2RR14 1VBD4 2B76A 1XHZA 3P4SA 3AEBA 1RUF4 3P4PA 1VBC4 1ZP0A 1H8TD 1RHI4 2FBWA 3SFDA 1RMU4 1RUH4 3P4QA 4YTMA 4Q4V4 1RUI4 2PYLA 2X5ID 1AR84 4YSYA 1R084 3AE9A 3VR8A 5C3JA 2RMU4 4Q4Y4 1HRI4 3VRBA 3AEGA 1VBE4 1AR94 1YQ4A 2HWB4 2R044 3AEEA 1VBB4 1KF6A 2PY5A 1YQ3A 1R094 3AEDA 2PZSA 2WDVA 1RUC4 1K5MD 4YSZA 1PIV4 1D4M4 1ASJ4 1HRV4 2EX3A 4RHV4 1XHXA 4YT0A 3AE5A 4YXDA 1AR64 4Q4X4 2PLV4 1PO24 3JBG4 2WDRA 1L0VA 3AE4A 1COV4 2WU5A 1AL24 4PDWD 1XI1A 2RS14 2RM24 2H89A 1VBA4 3AE7A 3AE6A 2H88A 1NCQD 3CIRA 4YSXA 2HWC4 1ZOYA 2R7FA 1Z7S4 3ABVA 2WP9A 3GQHA 1EAH4 1EV14 1VRH4 3AE3A 3SFEA 1KFYA 4Q4W4 1RUE4 2RS54 2WDQA 2WS3A 1NENA 1NEKA 2WQYA 1RVF4 4KX6A 1HXS4 1NA1D 3AE1A 3SUCA 3FI7A 1POV0 2ACZA 4YTPA 1AR74 4GB34
chains in the Genus database with same CATH topology
1NCQD 1H8TD 1RHI4 1K5MD 3J8F4 2HWC4 1PIV4 1VBC4 1D4M4 1OOPD 1RMU4 1RUH4 1ASJ4 1Z7S4 1RUD4 2R074 1HRV4 4Q4V4 1RUI4 2RS34 4RHV4 1PVC4 1PO14 2R064 1MQTD 1AR64 1BEV4 1EAH4 1AR84 1EV14 1VRH4 2PLV4 1R084 2X5ID 4Q4X4 1PO24 1RUG4 4Q4W4 1RUJ4 2RMU4 1HRI4 3JBG4 4Q4Y4 1RUE4 2RS54 1COV4 3JD74 1VBE4 1RVF4 2RR14 1VBD4 1AL24 1AR94 1HXS4 1NA1D 2HWB4 2R044 2RS14 2RM24 4PDWD 1RUF4 1POV0 1VBA4 1VBB4 1AR74 1R094 4GB34 1RUC4
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NCQ D;  1H8T D;  1RHI 4;  1K5M D;  3J8F 4;  2HWC 4;  1PIV 4;  1VBC 4;  1D4M 4;  1OOP D;  1RMU 4;  1RUH 4;  1ASJ 4;  1Z7S 4;  1RUD 4;  2R07 4;  1HRV 4;  4Q4V 4;  1RUI 4;  2RS3 4;  4RHV 4;  1PVC 4;  1PO1 4;  2R06 4;  1MQT D;  1AR6 4;  1BEV 4;  1EAH 4;  1AR8 4;  1EV1 4;  1VRH 4;  2PLV 4;  1R08 4;  2X5I D;  4Q4X 4;  1PO2 4;  1RUG 4;  4Q4W 4;  1RUJ 4;  2RMU 4;  1HRI 4;  3JBG 4;  4Q4Y 4;  1RUE 4;  2RS5 4;  1COV 4;  3JD7 4;  1VBE 4;  1RVF 4;  2RR1 4;  1VBD 4;  1AL2 4;  1AR9 4;  1HXS 4;  1NA1 D;  2HWB 4;  2R04 4;  2RS1 4;  2RM2 4;  4PDW D;  1RUF 4;  1POV 0;  1VBA 4;  1VBB 4;  1AR7 4;  1R09 4;  4GB3 4;  1RUC 4; 
#chains in the Genus database with same CATH topology
 3J8F 4;  2PW9 A;  3AE8 A;  1OOP D;  1RUD 4;  3VR9 A;  2R07 4;  3AEA A;  3AE2 A;  2RS3 4;  1PVC 4;  1PO1 4;  2R06 4;  1MQT D;  1BEV 4;  3AEC A;  2WU2 A;  4YTN A;  2PYJ A;  1RUG 4;  1RUJ 4;  3VRA A;  5C2T A;  3AEF A;  3P4R A;  3GQK A;  3JD7 4;  2RR1 4;  1VBD 4;  2B76 A;  1XHZ A;  3P4S A;  3AEB A;  1RUF 4;  3P4P A;  1VBC 4;  1ZP0 A;  1H8T D;  1RHI 4;  2FBW A;  3SFD A;  1RMU 4;  1RUH 4;  3P4Q A;  4YTM A;  4Q4V 4;  1RUI 4;  2PYL A;  2X5I D;  1AR8 4;  4YSY A;  1R08 4;  3AE9 A;  3VR8 A;  5C3J A;  2RMU 4;  4Q4Y 4;  1HRI 4;  3VRB A;  3AEG A;  1VBE 4;  1AR9 4;  1YQ4 A;  2HWB 4;  2R04 4;  3AEE A;  1VBB 4;  1KF6 A;  2PY5 A;  1YQ3 A;  1R09 4;  3AED A;  2PZS A;  2WDV A;  1RUC 4;  1K5M D;  4YSZ A;  1PIV 4;  1D4M 4;  1ASJ 4;  1HRV 4;  2EX3 A;  4RHV 4;  1XHX A;  4YT0 A;  3AE5 A;  4YXD A;  1AR6 4;  4Q4X 4;  2PLV 4;  1PO2 4;  3JBG 4;  2WDR A;  1L0V A;  3AE4 A;  1COV 4;  2WU5 A;  1AL2 4;  4PDW D;  1XI1 A;  2RS1 4;  2RM2 4;  2H89 A;  1VBA 4;  3AE7 A;  3AE6 A;  2H88 A;  1NCQ D;  3CIR A;  4YSX A;  2HWC 4;  1ZOY A;  2R7F A;  1Z7S 4;  3ABV A;  2WP9 A;  3GQH A;  1EAH 4;  1EV1 4;  1VRH 4;  3AE3 A;  3SFE A;  1KFY A;  4Q4W 4;  1RUE 4;  2RS5 4;  2WDQ A;  2WS3 A;  1NEN A;  1NEK A;  2WQY A;  1RVF 4;  4KX6 A;  1HXS 4;  1NA1 D;  3AE1 A;  3SUC A;  3FI7 A;  1POV 0;  2ACZ A;  4YTP A;  1AR7 4;  4GB3 4; 
#chains in the Genus database with same CATH homology
 1NCQ D;  1H8T D;  1RHI 4;  1K5M D;  3J8F 4;  2HWC 4;  1PIV 4;  1VBC 4;  1D4M 4;  1OOP D;  1RMU 4;  1RUH 4;  1ASJ 4;  1Z7S 4;  1RUD 4;  2R07 4;  1HRV 4;  4Q4V 4;  1RUI 4;  2RS3 4;  4RHV 4;  1PVC 4;  1PO1 4;  2R06 4;  1MQT D;  1AR6 4;  1BEV 4;  1EAH 4;  1AR8 4;  1EV1 4;  1VRH 4;  2PLV 4;  1R08 4;  2X5I D;  4Q4X 4;  1PO2 4;  1RUG 4;  4Q4W 4;  1RUJ 4;  2RMU 4;  1HRI 4;  3JBG 4;  4Q4Y 4;  1RUE 4;  2RS5 4;  1COV 4;  3JD7 4;  1VBE 4;  1RVF 4;  2RR1 4;  1VBD 4;  1AL2 4;  1AR9 4;  1HXS 4;  1NA1 D;  2HWB 4;  2R04 4;  2RS1 4;  2RM2 4;  4PDW D;  1RUF 4;  1POV 0;  1VBA 4;  1VBB 4;  1AR7 4;  1R09 4;  4GB3 4;  1RUC 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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