1PO24

Poliovirus (type 1, mahoney) in complex with r77975, an inhibitor of viral replication
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYRDSASNAASKQDFSQDPSKFTEPIKDVLIKTAPMLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Virus
publication title Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
pubmed doi rcsb
molecule keywords POLIOVIRUS TYPE 1 MAHONEY
total genus 5
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1997-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1po2400
4GB34 2R064 1HRI4 2X5ID 4Q4V4 1RUC4 1K5MD 1VRH4 1D4M4 1PO14 2RS14 1H8TD 1RUI4 2RS54 1R094 3J8F4 1RUJ4 2RS34 1Z7S4 4RHV4 1HXS4 2R044 4Q4X4 2R074 1EV14 1ASJ4 2RR14 1POV0 1PIV4 1RUD4 2HWB4 1PO24 1RMU4 4Q4W4 1VBE4 1VBB4 1AR84 2RMU4 1RUF4 1OOPD 1EAH4 1NA1D 1RVF4 4Q4Y4 1RHI4 3JBG4 1VBC4 1AR94 1VBA4 1COV4 1R084 2PLV4 1AR64 1AL24 1RUH4 1RUG4 1RUE4 1VBD4 3JD74 1AR74 1BEV4 1MQTD 2HWC4 4PDWD 1PVC4 1NCQD 1HRV4 2RM24
chains in the Genus database with same CATH superfamily
4GB34 2X5ID 4Q4V4 3AE2A 1K5MD 5C2TA 1VRH4 1KFYA 2WDRA 1RUJ4 1Z7S4 3AEFA 4YXDA 1EV14 3GQKA 3SFDA 2WDQA 4Q4W4 1RMU4 3AE4A 1NEKA 2RMU4 1KF6A 1RVF4 3AE7A 3CIRA 1RHI4 3AEEA 4YSXA 1VBA4 2WDVA 1AR64 3VRAA 3AE5A 2PZSA 3JD74 4YTPA 1BEV4 1HRV4 2PW9A 1D4M4 2FBWA 1H8TD 3AEBA 3J8F4 1NENA 3VRBA 3AE9A 4Q4X4 2RR14 1XHXA 1PO24 2H88A 1VBE4 1VBB4 1AR84 1L0VA 1OOPD 1NA1D 4YT0A 4YTMA 1AR94 3GQHA 2PLV4 1AL24 1ZOYA 1RUG4 2WS3A 1MQTD 4PDWD 1NCQD 4YSYA 1HRI4 1RUC4 1PO14 2RS54 1RUI4 1R094 2RS34 1HXS4 2R044 1ASJ4 2WP9A 4YSZA 1XI1A 1RUD4 2PY5A 1YQ3A 1RUF4 3AE3A 3SUCA 1EAH4 3AEAA 3AEGA 2ACZA 1VBC4 3AE6A 3AEDA 5C3JA 3AE1A 1RUE4 1VBD4 2B76A 1PVC4 3AE8A 2R064 3P4QA 4KX6A 2R7FA 3P4RA 3VR8A 2RS14 4RHV4 2R074 3P4SA 4YTNA 1POV0 2WU5A 1PIV4 2HWB4 3AECA 2H89A 3ABVA 1XHZA 4Q4Y4 3JBG4 2WU2A 3P4PA 1COV4 3SFEA 1R084 2WQYA 1RUH4 2PYLA 1AR74 2PYJA 1ZP0A 2HWC4 3VR9A 3FI7A 1YQ4A 2EX3A 2RM24
chains in the Genus database with same CATH topology
4GB34 2R064 1HRI4 2X5ID 4Q4V4 1RUC4 1K5MD 1VRH4 1D4M4 1PO14 2RS14 1H8TD 1RUI4 2RS54 1R094 3J8F4 1RUJ4 2RS34 1Z7S4 4RHV4 1HXS4 2R044 4Q4X4 2R074 1EV14 1ASJ4 2RR14 1POV0 1PIV4 1RUD4 2HWB4 1PO24 1RMU4 4Q4W4 1VBE4 1VBB4 1AR84 2RMU4 1RUF4 1OOPD 1EAH4 1NA1D 1RVF4 4Q4Y4 1RHI4 3JBG4 1VBC4 1AR94 1VBA4 1COV4 1R084 2PLV4 1AR64 1AL24 1RUH4 1RUG4 1RUE4 1VBD4 3JD74 1AR74 1BEV4 1MQTD 2HWC4 4PDWD 1PVC4 1NCQD 1HRV4 2RM24
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GB3 4;  2R06 4;  1HRI 4;  2X5I D;  4Q4V 4;  1RUC 4;  1K5M D;  1VRH 4;  1D4M 4;  1PO1 4;  2RS1 4;  1H8T D;  1RUI 4;  2RS5 4;  1R09 4;  3J8F 4;  1RUJ 4;  2RS3 4;  1Z7S 4;  4RHV 4;  1HXS 4;  2R04 4;  4Q4X 4;  2R07 4;  1EV1 4;  1ASJ 4;  2RR1 4;  1POV 0;  1PIV 4;  1RUD 4;  2HWB 4;  1PO2 4;  1RMU 4;  4Q4W 4;  1VBE 4;  1VBB 4;  1AR8 4;  2RMU 4;  1RUF 4;  1OOP D;  1EAH 4;  1NA1 D;  1RVF 4;  4Q4Y 4;  1RHI 4;  3JBG 4;  1VBC 4;  1AR9 4;  1VBA 4;  1COV 4;  1R08 4;  2PLV 4;  1AR6 4;  1AL2 4;  1RUH 4;  1RUG 4;  1RUE 4;  1VBD 4;  3JD7 4;  1AR7 4;  1BEV 4;  1MQT D;  2HWC 4;  4PDW D;  1PVC 4;  1NCQ D;  1HRV 4;  2RM2 4; 
#chains in the Genus database with same CATH topology
 4GB3 4;  2X5I D;  4Q4V 4;  3AE2 A;  1K5M D;  5C2T A;  1VRH 4;  1KFY A;  2WDR A;  1RUJ 4;  1Z7S 4;  3AEF A;  4YXD A;  1EV1 4;  3GQK A;  3SFD A;  2WDQ A;  4Q4W 4;  1RMU 4;  3AE4 A;  1NEK A;  2RMU 4;  1KF6 A;  1RVF 4;  3AE7 A;  3CIR A;  1RHI 4;  3AEE A;  4YSX A;  1VBA 4;  2WDV A;  1AR6 4;  3VRA A;  3AE5 A;  2PZS A;  3JD7 4;  4YTP A;  1BEV 4;  1HRV 4;  2PW9 A;  1D4M 4;  2FBW A;  1H8T D;  3AEB A;  3J8F 4;  1NEN A;  3VRB A;  3AE9 A;  4Q4X 4;  2RR1 4;  1XHX A;  1PO2 4;  2H88 A;  1VBE 4;  1VBB 4;  1AR8 4;  1L0V A;  1OOP D;  1NA1 D;  4YT0 A;  4YTM A;  1AR9 4;  3GQH A;  2PLV 4;  1AL2 4;  1ZOY A;  1RUG 4;  2WS3 A;  1MQT D;  4PDW D;  1NCQ D;  4YSY A;  1HRI 4;  1RUC 4;  1PO1 4;  2RS5 4;  1RUI 4;  1R09 4;  2RS3 4;  1HXS 4;  2R04 4;  1ASJ 4;  2WP9 A;  4YSZ A;  1XI1 A;  1RUD 4;  2PY5 A;  1YQ3 A;  1RUF 4;  3AE3 A;  3SUC A;  1EAH 4;  3AEA A;  3AEG A;  2ACZ A;  1VBC 4;  3AE6 A;  3AED A;  5C3J A;  3AE1 A;  1RUE 4;  1VBD 4;  2B76 A;  1PVC 4;  3AE8 A;  2R06 4;  3P4Q A;  4KX6 A;  2R7F A;  3P4R A;  3VR8 A;  2RS1 4;  4RHV 4;  2R07 4;  3P4S A;  4YTN A;  1POV 0;  2WU5 A;  1PIV 4;  2HWB 4;  3AEC A;  2H89 A;  3ABV A;  1XHZ A;  4Q4Y 4;  3JBG 4;  2WU2 A;  3P4P A;  1COV 4;  3SFE A;  1R08 4;  2WQY A;  1RUH 4;  2PYL A;  1AR7 4;  2PYJ A;  1ZP0 A;  2HWC 4;  3VR9 A;  3FI7 A;  1YQ4 A;  2EX3 A;  2RM2 4; 
#chains in the Genus database with same CATH homology
 4GB3 4;  2R06 4;  1HRI 4;  2X5I D;  4Q4V 4;  1RUC 4;  1K5M D;  1VRH 4;  1D4M 4;  1PO1 4;  2RS1 4;  1H8T D;  1RUI 4;  2RS5 4;  1R09 4;  3J8F 4;  1RUJ 4;  2RS3 4;  1Z7S 4;  4RHV 4;  1HXS 4;  2R04 4;  4Q4X 4;  2R07 4;  1EV1 4;  1ASJ 4;  2RR1 4;  1POV 0;  1PIV 4;  1RUD 4;  2HWB 4;  1PO2 4;  1RMU 4;  4Q4W 4;  1VBE 4;  1VBB 4;  1AR8 4;  2RMU 4;  1RUF 4;  1OOP D;  1EAH 4;  1NA1 D;  1RVF 4;  4Q4Y 4;  1RHI 4;  3JBG 4;  1VBC 4;  1AR9 4;  1VBA 4;  1COV 4;  1R08 4;  2PLV 4;  1AR6 4;  1AL2 4;  1RUH 4;  1RUG 4;  1RUE 4;  1VBD 4;  3JD7 4;  1AR7 4;  1BEV 4;  1MQT D;  2HWC 4;  4PDW D;  1PVC 4;  1NCQ D;  1HRV 4;  2RM2 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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