1PIV4

Binding of the antiviral drug win51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYKDSASNAASKQDYSQDPSKFTEPLKDVLIKTAPALN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
pubmed doi rcsb
molecule tags Virus
source organism Poliovirus type 3 (strains p3/leon/37 and p3/leon 12a[1]b)
molecule keywords POLIOVIRUS TYPE 3 (SUBUNIT VP1)
total genus 4
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1995-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1piv400
1K5MD 2RMU4 1OOPD 1POV0 1COV4 1ASJ4 2RS54 1RUH4 1RVF4 1HXS4 1R094 1Z7S4 1AR94 1NCQD 1BEV4 1D4M4 1VBA4 2R064 2RR14 3J8F4 3JD74 4GB34 4Q4X4 4RHV4 2X5ID 1HRV4 1AR74 2R074 1AR84 1NA1D 1AL24 1VBD4 2RS14 1EAH4 1RUG4 1PO14 1PVC4 1RUC4 2HWB4 2RS34 1HRI4 1AR64 1PIV4 1RHI4 4PDWD 4Q4V4 1H8TD 1MQTD 1VBE4 1VBC4 1PO24 1RUF4 1RUE4 3JBG4 2PLV4 2RM24 1RUD4 1RMU4 2R044 1VBB4 1R084 4Q4W4 4Q4Y4 2HWC4 1VRH4 1RUJ4 1EV14 1RUI4
chains in the Genus database with same CATH superfamily
1K5MD 1OOPD 1POV0 3P4PA 2PY5A 2WDVA 1ASJ4 3GQKA 1HXS4 1R094 4KX6A 3AEEA 1D4M4 1VBA4 3AE3A 4GB34 3AEBA 2R074 3AE5A 2WP9A 1ZP0A 3VRAA 2PZSA 1PVC4 3VR9A 2HWB4 2WQYA 4Q4V4 4PDWD 3P4QA 2R7FA 3VRBA 1RUE4 2PLV4 1RMU4 2ACZA 5C3JA 1VBB4 2HWC4 1NEKA 3AEDA 1H8TD 1EV14 3CIRA 3J8F4 1RUI4 3AE9A 3ABVA 1XHZA 1Z7S4 4YTPA 1XI1A 3FI7A 1YQ3A 2X5ID 4YTNA 2WU2A 3VR8A 3AE4A 2WU5A 3AEGA 3AE1A 1VBD4 2RS14 3SFEA 1RUC4 1HRI4 1AR64 1PIV4 1MQTD 1VBE4 2PW9A 1XHXA 3JBG4 1RUD4 2R044 3P4SA 4YT0A 1VRH4 4YTMA 1COV4 2PYJA 1RUH4 1RVF4 1BEV4 1NCQD 2RR14 3JD74 1L0VA 4RHV4 3GQHA 2EX3A 2WDQA 3AECA 4YXDA 1AR84 1NA1D 1AL24 1ZOYA 3SUCA 2WS3A 3AE2A 1PO14 1VBC4 3AE7A 3AEFA 2FBWA 1KF6A 1R084 3P4RA 3AE8A 2PYLA 1RUJ4 2RMU4 3SFDA 1NENA 1KFYA 5C2TA 4YSXA 2RS54 1AR94 4Q4X4 1YQ4A 2H88A 2R064 1HRV4 4YSYA 1AR74 1EAH4 1RUG4 4YSZA 2RS34 2WDRA 1RHI4 1PO24 1RUF4 2H89A 2RM24 2B76A 4Q4W4 4Q4Y4 3AE6A 3AEAA
chains in the Genus database with same CATH topology
1K5MD 2RMU4 1OOPD 1POV0 1COV4 1ASJ4 2RS54 1RUH4 1RVF4 1HXS4 1R094 1Z7S4 1AR94 1NCQD 1BEV4 1D4M4 1VBA4 2R064 2RR14 3J8F4 3JD74 4GB34 4Q4X4 4RHV4 2X5ID 1HRV4 1AR74 2R074 1AR84 1NA1D 1AL24 1VBD4 2RS14 1EAH4 1RUG4 1PO14 1PVC4 1RUC4 2HWB4 2RS34 1HRI4 1AR64 1PIV4 1RHI4 4PDWD 4Q4V4 1H8TD 1MQTD 1VBE4 1VBC4 1PO24 1RUF4 1RUE4 3JBG4 2PLV4 2RM24 1RUD4 1RMU4 2R044 1VBB4 1R084 4Q4W4 4Q4Y4 2HWC4 1VRH4 1RUJ4 1EV14 1RUI4
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K5M D;  2RMU 4;  1OOP D;  1POV 0;  1COV 4;  1ASJ 4;  2RS5 4;  1RUH 4;  1RVF 4;  1HXS 4;  1R09 4;  1Z7S 4;  1AR9 4;  1NCQ D;  1BEV 4;  1D4M 4;  1VBA 4;  2R06 4;  2RR1 4;  3J8F 4;  3JD7 4;  4GB3 4;  4Q4X 4;  4RHV 4;  2X5I D;  1HRV 4;  1AR7 4;  2R07 4;  1AR8 4;  1NA1 D;  1AL2 4;  1VBD 4;  2RS1 4;  1EAH 4;  1RUG 4;  1PO1 4;  1PVC 4;  1RUC 4;  2HWB 4;  2RS3 4;  1HRI 4;  1AR6 4;  1PIV 4;  1RHI 4;  4PDW D;  4Q4V 4;  1H8T D;  1MQT D;  1VBE 4;  1VBC 4;  1PO2 4;  1RUF 4;  1RUE 4;  3JBG 4;  2PLV 4;  2RM2 4;  1RUD 4;  1RMU 4;  2R04 4;  1VBB 4;  1R08 4;  4Q4W 4;  4Q4Y 4;  2HWC 4;  1VRH 4;  1RUJ 4;  1EV1 4;  1RUI 4; 
#chains in the Genus database with same CATH topology
 1K5M D;  1OOP D;  1POV 0;  3P4P A;  2PY5 A;  2WDV A;  1ASJ 4;  3GQK A;  1HXS 4;  1R09 4;  4KX6 A;  3AEE A;  1D4M 4;  1VBA 4;  3AE3 A;  4GB3 4;  3AEB A;  2R07 4;  3AE5 A;  2WP9 A;  1ZP0 A;  3VRA A;  2PZS A;  1PVC 4;  3VR9 A;  2HWB 4;  2WQY A;  4Q4V 4;  4PDW D;  3P4Q A;  2R7F A;  3VRB A;  1RUE 4;  2PLV 4;  1RMU 4;  2ACZ A;  5C3J A;  1VBB 4;  2HWC 4;  1NEK A;  3AED A;  1H8T D;  1EV1 4;  3CIR A;  3J8F 4;  1RUI 4;  3AE9 A;  3ABV A;  1XHZ A;  1Z7S 4;  4YTP A;  1XI1 A;  3FI7 A;  1YQ3 A;  2X5I D;  4YTN A;  2WU2 A;  3VR8 A;  3AE4 A;  2WU5 A;  3AEG A;  3AE1 A;  1VBD 4;  2RS1 4;  3SFE A;  1RUC 4;  1HRI 4;  1AR6 4;  1PIV 4;  1MQT D;  1VBE 4;  2PW9 A;  1XHX A;  3JBG 4;  1RUD 4;  2R04 4;  3P4S A;  4YT0 A;  1VRH 4;  4YTM A;  1COV 4;  2PYJ A;  1RUH 4;  1RVF 4;  1BEV 4;  1NCQ D;  2RR1 4;  3JD7 4;  1L0V A;  4RHV 4;  3GQH A;  2EX3 A;  2WDQ A;  3AEC A;  4YXD A;  1AR8 4;  1NA1 D;  1AL2 4;  1ZOY A;  3SUC A;  2WS3 A;  3AE2 A;  1PO1 4;  1VBC 4;  3AE7 A;  3AEF A;  2FBW A;  1KF6 A;  1R08 4;  3P4R A;  3AE8 A;  2PYL A;  1RUJ 4;  2RMU 4;  3SFD A;  1NEN A;  1KFY A;  5C2T A;  4YSX A;  2RS5 4;  1AR9 4;  4Q4X 4;  1YQ4 A;  2H88 A;  2R06 4;  1HRV 4;  4YSY A;  1AR7 4;  1EAH 4;  1RUG 4;  4YSZ A;  2RS3 4;  2WDR A;  1RHI 4;  1PO2 4;  1RUF 4;  2H89 A;  2RM2 4;  2B76 A;  4Q4W 4;  4Q4Y 4;  3AE6 A;  3AEA A; 
#chains in the Genus database with same CATH homology
 1K5M D;  2RMU 4;  1OOP D;  1POV 0;  1COV 4;  1ASJ 4;  2RS5 4;  1RUH 4;  1RVF 4;  1HXS 4;  1R09 4;  1Z7S 4;  1AR9 4;  1NCQ D;  1BEV 4;  1D4M 4;  1VBA 4;  2R06 4;  2RR1 4;  3J8F 4;  3JD7 4;  4GB3 4;  4Q4X 4;  4RHV 4;  2X5I D;  1HRV 4;  1AR7 4;  2R07 4;  1AR8 4;  1NA1 D;  1AL2 4;  1VBD 4;  2RS1 4;  1EAH 4;  1RUG 4;  1PO1 4;  1PVC 4;  1RUC 4;  2HWB 4;  2RS3 4;  1HRI 4;  1AR6 4;  1PIV 4;  1RHI 4;  4PDW D;  4Q4V 4;  1H8T D;  1MQT D;  1VBE 4;  1VBC 4;  1PO2 4;  1RUF 4;  1RUE 4;  3JBG 4;  2PLV 4;  2RM2 4;  1RUD 4;  1RMU 4;  2R04 4;  1VBB 4;  1R08 4;  4Q4W 4;  4Q4Y 4;  2HWC 4;  1VRH 4;  1RUJ 4;  1EV1 4;  1RUI 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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