1PO14

Poliovirus (type 1, mahoney) in complex with r80633, an inhibitor of viral replication
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYRDSASNAASKQDFSQDPSKFTEPIKDVLIKTAPMLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
pubmed doi rcsb
molecule tags Virus
molecule keywords POLIOVIRUS TYPE 1 MAHONEY
total genus 4
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1997-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1po1400
1AR64 1MQTD 1RUD4 1ASJ4 1RVF4 2PLV4 2RMU4 1AR94 1RMU4 4Q4V4 2RS54 1HRI4 1RUH4 1VBC4 4Q4X4 4Q4Y4 1HRV4 1VRH4 2RR14 1POV0 2HWB4 2RS14 1RHI4 1PO14 4Q4W4 1Z7S4 1OOPD 1AR74 1VBD4 2R064 3JBG4 1NCQD 1R094 1R084 1RUF4 2R074 3J8F4 1VBE4 1HXS4 1EAH4 1AR84 1RUE4 1PO24 4PDWD 1BEV4 1D4M4 1H8TD 2RS34 1EV14 1VBA4 4RHV4 1PIV4 1AL24 1K5MD 1NA1D 1VBB4 1RUC4 1RUI4 1RUJ4 1RUG4 1PVC4 2R044 2X5ID 2RM24 2HWC4 1COV4 3JD74 4GB34
chains in the Genus database with same CATH superfamily
1MQTD 1RUD4 1RVF4 1ASJ4 2PW9A 1ZP0A 2RMU4 2WQYA 1L0VA 4YSXA 1HRV4 2WDVA 1NENA 2PZSA 1ZOYA 1Z7S4 1AR74 1R084 1KFYA 3SFEA 1HXS4 3AE3A 4PDWD 4YXDA 2RS34 1D4M4 3SUCA 1PIV4 3AE2A 3P4QA 1NEKA 3AE4A 1XHXA 2RR14 3AEBA 1AR64 2PYLA 1AR94 1RMU4 1HRI4 1RUH4 4Q4X4 4Q4Y4 5C2TA 1XHZA 2H89A 2RS14 4Q4W4 1PO14 1YQ4A 2WDQA 1RUF4 3AEEA 3J8F4 1EAH4 1AR84 1RUE4 3AE7A 3AEAA 5C3JA 1EV14 3P4SA 2WS3A 1VBA4 3AE1A 1K5MD 1NA1D 1RUJ4 1PVC4 2H88A 3P4PA 2X5ID 2RM24 2HWC4 3JD74 2WP9A 3CIRA 3ABVA 3FI7A 2B76A 1POV0 2HWB4 1XI1A 1RHI4 3AE6A 1OOPD 3JBG4 4YT0A 2R074 4YTMA 4YSYA 4YSZA 3VR8A 3AECA 1PO24 3AE9A 2PYJA 2ACZA 2PY5A 3GQHA 1RUC4 1RUI4 1RUG4 2WU5A 4KX6A 2R7FA 3AEGA 3AE5A 2PLV4 4Q4V4 2RS54 1VBC4 3VR9A 3AEFA 4YTPA 4YTNA 1VRH4 2FBWA 3GQKA 1VBD4 2R064 1NCQD 1R094 1VBE4 1YQ3A 2WU2A 1BEV4 1H8TD 4RHV4 3VRAA 2WDRA 1AL24 1VBB4 3AE8A 2EX3A 3VRBA 1KF6A 2R044 3AEDA 3P4RA 1COV4 3SFDA 4GB34
chains in the Genus database with same CATH topology
1AR64 1MQTD 1RUD4 1ASJ4 1RVF4 2PLV4 2RMU4 1AR94 1RMU4 4Q4V4 2RS54 1HRI4 1RUH4 1VBC4 4Q4X4 4Q4Y4 1HRV4 1VRH4 2RR14 1POV0 2HWB4 2RS14 1RHI4 1PO14 4Q4W4 1Z7S4 1OOPD 1AR74 1VBD4 2R064 3JBG4 1NCQD 1R094 1R084 1RUF4 2R074 3J8F4 1VBE4 1HXS4 1EAH4 1AR84 1RUE4 1PO24 4PDWD 1BEV4 1D4M4 1H8TD 2RS34 1EV14 1VBA4 4RHV4 1PIV4 1AL24 1K5MD 1NA1D 1VBB4 1RUC4 1RUI4 1RUJ4 1RUG4 1PVC4 2R044 2X5ID 2RM24 2HWC4 1COV4 3JD74 4GB34
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AR6 4;  1MQT D;  1RUD 4;  1ASJ 4;  1RVF 4;  2PLV 4;  2RMU 4;  1AR9 4;  1RMU 4;  4Q4V 4;  2RS5 4;  1HRI 4;  1RUH 4;  1VBC 4;  4Q4X 4;  4Q4Y 4;  1HRV 4;  1VRH 4;  2RR1 4;  1POV 0;  2HWB 4;  2RS1 4;  1RHI 4;  1PO1 4;  4Q4W 4;  1Z7S 4;  1OOP D;  1AR7 4;  1VBD 4;  2R06 4;  3JBG 4;  1NCQ D;  1R09 4;  1R08 4;  1RUF 4;  2R07 4;  3J8F 4;  1VBE 4;  1HXS 4;  1EAH 4;  1AR8 4;  1RUE 4;  1PO2 4;  4PDW D;  1BEV 4;  1D4M 4;  1H8T D;  2RS3 4;  1EV1 4;  1VBA 4;  4RHV 4;  1PIV 4;  1AL2 4;  1K5M D;  1NA1 D;  1VBB 4;  1RUC 4;  1RUI 4;  1RUJ 4;  1RUG 4;  1PVC 4;  2R04 4;  2X5I D;  2RM2 4;  2HWC 4;  1COV 4;  3JD7 4;  4GB3 4; 
#chains in the Genus database with same CATH topology
 1MQT D;  1RUD 4;  1RVF 4;  1ASJ 4;  2PW9 A;  1ZP0 A;  2RMU 4;  2WQY A;  1L0V A;  4YSX A;  1HRV 4;  2WDV A;  1NEN A;  2PZS A;  1ZOY A;  1Z7S 4;  1AR7 4;  1R08 4;  1KFY A;  3SFE A;  1HXS 4;  3AE3 A;  4PDW D;  4YXD A;  2RS3 4;  1D4M 4;  3SUC A;  1PIV 4;  3AE2 A;  3P4Q A;  1NEK A;  3AE4 A;  1XHX A;  2RR1 4;  3AEB A;  1AR6 4;  2PYL A;  1AR9 4;  1RMU 4;  1HRI 4;  1RUH 4;  4Q4X 4;  4Q4Y 4;  5C2T A;  1XHZ A;  2H89 A;  2RS1 4;  4Q4W 4;  1PO1 4;  1YQ4 A;  2WDQ A;  1RUF 4;  3AEE A;  3J8F 4;  1EAH 4;  1AR8 4;  1RUE 4;  3AE7 A;  3AEA A;  5C3J A;  1EV1 4;  3P4S A;  2WS3 A;  1VBA 4;  3AE1 A;  1K5M D;  1NA1 D;  1RUJ 4;  1PVC 4;  2H88 A;  3P4P A;  2X5I D;  2RM2 4;  2HWC 4;  3JD7 4;  2WP9 A;  3CIR A;  3ABV A;  3FI7 A;  2B76 A;  1POV 0;  2HWB 4;  1XI1 A;  1RHI 4;  3AE6 A;  1OOP D;  3JBG 4;  4YT0 A;  2R07 4;  4YTM A;  4YSY A;  4YSZ A;  3VR8 A;  3AEC A;  1PO2 4;  3AE9 A;  2PYJ A;  2ACZ A;  2PY5 A;  3GQH A;  1RUC 4;  1RUI 4;  1RUG 4;  2WU5 A;  4KX6 A;  2R7F A;  3AEG A;  3AE5 A;  2PLV 4;  4Q4V 4;  2RS5 4;  1VBC 4;  3VR9 A;  3AEF A;  4YTP A;  4YTN A;  1VRH 4;  2FBW A;  3GQK A;  1VBD 4;  2R06 4;  1NCQ D;  1R09 4;  1VBE 4;  1YQ3 A;  2WU2 A;  1BEV 4;  1H8T D;  4RHV 4;  3VRA A;  2WDR A;  1AL2 4;  1VBB 4;  3AE8 A;  2EX3 A;  3VRB A;  1KF6 A;  2R04 4;  3AED A;  3P4R A;  1COV 4;  3SFD A;  4GB3 4; 
#chains in the Genus database with same CATH homology
 1AR6 4;  1MQT D;  1RUD 4;  1ASJ 4;  1RVF 4;  2PLV 4;  2RMU 4;  1AR9 4;  1RMU 4;  4Q4V 4;  2RS5 4;  1HRI 4;  1RUH 4;  1VBC 4;  4Q4X 4;  4Q4Y 4;  1HRV 4;  1VRH 4;  2RR1 4;  1POV 0;  2HWB 4;  2RS1 4;  1RHI 4;  1PO1 4;  4Q4W 4;  1Z7S 4;  1OOP D;  1AR7 4;  1VBD 4;  2R06 4;  3JBG 4;  1NCQ D;  1R09 4;  1R08 4;  1RUF 4;  2R07 4;  3J8F 4;  1VBE 4;  1HXS 4;  1EAH 4;  1AR8 4;  1RUE 4;  1PO2 4;  4PDW D;  1BEV 4;  1D4M 4;  1H8T D;  2RS3 4;  1EV1 4;  1VBA 4;  4RHV 4;  1PIV 4;  1AL2 4;  1K5M D;  1NA1 D;  1VBB 4;  1RUC 4;  1RUI 4;  1RUJ 4;  1RUG 4;  1PVC 4;  2R04 4;  2X5I D;  2RM2 4;  2HWC 4;  1COV 4;  3JD7 4;  4GB3 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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