1PO24

Poliovirus (type 1, mahoney) in complex with r77975, an inhibitor of viral replication
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYRDSASNAASKQDFSQDPSKFTEPIKDVLIKTAPMLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
pubmed doi rcsb
molecule tags Virus
molecule keywords POLIOVIRUS TYPE 1 MAHONEY
total genus 5
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1997-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1po2400
1RUF4 2RM24 1AR74 1R094 1AR84 1NCQD 1RUE4 2R064 2R074 3JD74 4PDWD 1MQTD 1RUG4 1PO14 2PLV4 4GB34 1PO24 1VBB4 1HRI4 1VRH4 2X5ID 1AL24 1RHI4 1RUC4 1RMU4 1VBE4 4Q4V4 1D4M4 1NA1D 1OOPD 1AR64 2RS14 1ASJ4 2RMU4 1PIV4 1COV4 3J8F4 1VBC4 4Q4Y4 2RS34 4RHV4 1RUH4 1VBA4 1RVF4 1POV0 1RUI4 1K5MD 1VBD4 1Z7S4 1AR94 1EV14 2HWB4 2R044 2HWC4 1EAH4 1HRV4 1RUD4 3JBG4 1H8TD 1HXS4 1BEV4 1R084 1RUJ4 2RS54 1PVC4 4Q4X4 2RR14 4Q4W4
chains in the Genus database with same CATH superfamily
2RM24 2PYLA 1R094 3JD74 1RUE4 2WQYA 1PO14 1ZP0A 1PO24 3VR8A 1NEKA 4Q4V4 4YSZA 1AR64 1ZOYA 2RMU4 1NENA 4RHV4 2RS34 1RUH4 2WU2A 3AEEA 1Z7S4 2WDVA 2WU5A 1HXS4 1BEV4 1R084 1RUJ4 4Q4Y4 5C3JA 1NCQD 2R064 3AE4A 4YTMA 1MQTD 2PLV4 4YSYA 4GB34 1RUC4 1XHZA 2EX3A 3AE5A 1OOPD 3AE1A 1ASJ4 2H88A 5C2TA 1YQ3A 3AECA 1PIV4 1VBC4 4KX6A 1VBA4 2PZSA 1RUI4 2R7FA 1KFYA 1HRV4 2HWC4 1EAH4 2WP9A 3VRAA 4YSXA 2PW9A 2PY5A 3SFEA 2RR14 3AE3A 4YTNA 1AR74 2H89A 1AR84 3AE9A 1RUG4 3VRBA 3AEGA 3GQKA 1VBB4 1HRI4 3AE6A 2X5ID 3AE7A 1RHI4 1RMU4 1L0VA 3AEBA 2B76A 3J8F4 3GQHA 4YXDA 1POV0 2HWB4 2R044 3P4PA 2WDRA 3P4RA 4YTPA 3AEAA 1PVC4 2WS3A 1XHXA 2ACZA 3P4SA 1RUF4 4PDWD 2R074 1XI1A 3VR9A 3AEFA 2PYJA 1VRH4 1AL24 3CIRA 1VBE4 1YQ4A 1D4M4 1NA1D 3P4QA 2RS14 3SUCA 3AE8A 1COV4 3ABVA 1RVF4 2WDQA 4YT0A 1VBD4 1K5MD 1KF6A 1AR94 1EV14 1RUD4 3FI7A 2FBWA 3JBG4 3AEDA 1H8TD 3SFDA 3AE2A 2RS54 4Q4X4 4Q4W4
chains in the Genus database with same CATH topology
1RUF4 2RM24 1AR74 1R094 1AR84 1NCQD 1RUE4 2R064 2R074 3JD74 4PDWD 1MQTD 1RUG4 1PO14 2PLV4 4GB34 1PO24 1VBB4 1HRI4 1VRH4 2X5ID 1AL24 1RHI4 1RUC4 1RMU4 1VBE4 4Q4V4 1D4M4 1NA1D 1OOPD 1AR64 2RS14 1ASJ4 2RMU4 1PIV4 1COV4 3J8F4 1VBC4 4Q4Y4 2RS34 4RHV4 1RUH4 1VBA4 1RVF4 1POV0 1RUI4 1K5MD 1VBD4 1Z7S4 1AR94 1EV14 2HWB4 2R044 2HWC4 1EAH4 1HRV4 1RUD4 3JBG4 1H8TD 1HXS4 1BEV4 1R084 1RUJ4 2RS54 1PVC4 4Q4X4 2RR14 4Q4W4
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RUF 4;  2RM2 4;  1AR7 4;  1R09 4;  1AR8 4;  1NCQ D;  1RUE 4;  2R06 4;  2R07 4;  3JD7 4;  4PDW D;  1MQT D;  1RUG 4;  1PO1 4;  2PLV 4;  4GB3 4;  1PO2 4;  1VBB 4;  1HRI 4;  1VRH 4;  2X5I D;  1AL2 4;  1RHI 4;  1RUC 4;  1RMU 4;  1VBE 4;  4Q4V 4;  1D4M 4;  1NA1 D;  1OOP D;  1AR6 4;  2RS1 4;  1ASJ 4;  2RMU 4;  1PIV 4;  1COV 4;  3J8F 4;  1VBC 4;  4Q4Y 4;  2RS3 4;  4RHV 4;  1RUH 4;  1VBA 4;  1RVF 4;  1POV 0;  1RUI 4;  1K5M D;  1VBD 4;  1Z7S 4;  1AR9 4;  1EV1 4;  2HWB 4;  2R04 4;  2HWC 4;  1EAH 4;  1HRV 4;  1RUD 4;  3JBG 4;  1H8T D;  1HXS 4;  1BEV 4;  1R08 4;  1RUJ 4;  2RS5 4;  1PVC 4;  4Q4X 4;  2RR1 4;  4Q4W 4; 
#chains in the Genus database with same CATH topology
 2RM2 4;  2PYL A;  1R09 4;  3JD7 4;  1RUE 4;  2WQY A;  1PO1 4;  1ZP0 A;  1PO2 4;  3VR8 A;  1NEK A;  4Q4V 4;  4YSZ A;  1AR6 4;  1ZOY A;  2RMU 4;  1NEN A;  4RHV 4;  2RS3 4;  1RUH 4;  2WU2 A;  3AEE A;  1Z7S 4;  2WDV A;  2WU5 A;  1HXS 4;  1BEV 4;  1R08 4;  1RUJ 4;  4Q4Y 4;  5C3J A;  1NCQ D;  2R06 4;  3AE4 A;  4YTM A;  1MQT D;  2PLV 4;  4YSY A;  4GB3 4;  1RUC 4;  1XHZ A;  2EX3 A;  3AE5 A;  1OOP D;  3AE1 A;  1ASJ 4;  2H88 A;  5C2T A;  1YQ3 A;  3AEC A;  1PIV 4;  1VBC 4;  4KX6 A;  1VBA 4;  2PZS A;  1RUI 4;  2R7F A;  1KFY A;  1HRV 4;  2HWC 4;  1EAH 4;  2WP9 A;  3VRA A;  4YSX A;  2PW9 A;  2PY5 A;  3SFE A;  2RR1 4;  3AE3 A;  4YTN A;  1AR7 4;  2H89 A;  1AR8 4;  3AE9 A;  1RUG 4;  3VRB A;  3AEG A;  3GQK A;  1VBB 4;  1HRI 4;  3AE6 A;  2X5I D;  3AE7 A;  1RHI 4;  1RMU 4;  1L0V A;  3AEB A;  2B76 A;  3J8F 4;  3GQH A;  4YXD A;  1POV 0;  2HWB 4;  2R04 4;  3P4P A;  2WDR A;  3P4R A;  4YTP A;  3AEA A;  1PVC 4;  2WS3 A;  1XHX A;  2ACZ A;  3P4S A;  1RUF 4;  4PDW D;  2R07 4;  1XI1 A;  3VR9 A;  3AEF A;  2PYJ A;  1VRH 4;  1AL2 4;  3CIR A;  1VBE 4;  1YQ4 A;  1D4M 4;  1NA1 D;  3P4Q A;  2RS1 4;  3SUC A;  3AE8 A;  1COV 4;  3ABV A;  1RVF 4;  2WDQ A;  4YT0 A;  1VBD 4;  1K5M D;  1KF6 A;  1AR9 4;  1EV1 4;  1RUD 4;  3FI7 A;  2FBW A;  3JBG 4;  3AED A;  1H8T D;  3SFD A;  3AE2 A;  2RS5 4;  4Q4X 4;  4Q4W 4; 
#chains in the Genus database with same CATH homology
 1RUF 4;  2RM2 4;  1AR7 4;  1R09 4;  1AR8 4;  1NCQ D;  1RUE 4;  2R06 4;  2R07 4;  3JD7 4;  4PDW D;  1MQT D;  1RUG 4;  1PO1 4;  2PLV 4;  4GB3 4;  1PO2 4;  1VBB 4;  1HRI 4;  1VRH 4;  2X5I D;  1AL2 4;  1RHI 4;  1RUC 4;  1RMU 4;  1VBE 4;  4Q4V 4;  1D4M 4;  1NA1 D;  1OOP D;  1AR6 4;  2RS1 4;  1ASJ 4;  2RMU 4;  1PIV 4;  1COV 4;  3J8F 4;  1VBC 4;  4Q4Y 4;  2RS3 4;  4RHV 4;  1RUH 4;  1VBA 4;  1RVF 4;  1POV 0;  1RUI 4;  1K5M D;  1VBD 4;  1Z7S 4;  1AR9 4;  1EV1 4;  2HWB 4;  2R04 4;  2HWC 4;  1EAH 4;  1HRV 4;  1RUD 4;  3JBG 4;  1H8T D;  1HXS 4;  1BEV 4;  1R08 4;  1RUJ 4;  2RS5 4;  1PVC 4;  4Q4X 4;  2RR1 4;  4Q4W 4; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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