2HWC | Genus

Total Genus 2

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	2
sequence length	40
structure length	40
Chain Sequence	INYYKDAASTSSAGQSLSMDPSKFTEPVKDLMLKGAPALN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Virus
source organism	Human rhinovirus 14
publication title	A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A. pubmed doi rcsb
molecule keywords	HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1)
total genus	2
structure length	40
sequence length	40
ec nomenclature	ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date	1994-01-25

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
4	PF02226	Pico_P1A	Picornavirus coat protein (VP4)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.80.10	Few Secondary Structures	Irregular	Rhinovirus 14, subunit 4	Picornavirus coat protein VP4	2hwc400

1RUD4 1RUH4 1VBB4 2X5ID 2R074 1AR94 1MQTD 2HWB4 1AR64 1NA1D 1VBD4 2RS54 1PO24 1HXS4 4GB34 2R064 1AR84 1VBC4 1RUJ4 1VRH4 1BEV4 3J8F4 1HRV4 3JD74 1K5MD 4Q4W4 1EAH4 1RMU4 1VBA4 2RS14 4PDWD 2RS34 4RHV4 1AR74 1POV0 1OOPD 1R094 1RUC4 1RUI4 1Z7S4 1R084 1ASJ4 1RHI4 4Q4X4 1COV4 2R044 1HRI4 1NCQD 1VBE4 1AL24 1PVC4 2HWC4 1PO14 1H8TD 1RUG4 2PLV4 1EV14 1RUE4 1RVF4 2RM24 3JBG4 2RMU4 1PIV4 4Q4V4 4Q4Y4 1RUF4 1D4M4 2RR14
chains in the Genus database with same CATH superfamily

4KX6A 1RUD4 3FI7A 4YSZA 1YQ3A 3P4RA 3AE3A 3AEGA 3P4SA 1AR94 1MQTD 1NEKA 1VBD4 2RS54 1HXS4 2PYLA 3VRBA 1VRH4 2PYJA 3JD74 1EAH4 4PDWD 1XI1A 2PW9A 1AR74 1Z7S4 3AE6A 2WQYA 1ASJ4 1XHXA 2B76A 2H88A 1COV4 2R044 1VBE4 1AL24 2HWC4 1RUE4 3VR8A 3AE9A 1RUH4 3AE2A 3AE7A 2R074 3AEEA 2WDVA 2WDQA 2R064 1AR84 3CIRA 1BEV4 3SUCA 1K5MD 2H89A 1RMU4 2RS14 3GQKA 4YTPA 1RUI4 3AEAA 4YT0A 5C2TA 4Q4X4 3VRAA 1HRI4 4YSYA 1L0VA 4RHV4 1PO14 1H8TD 1EV14 2RM24 4Q4Y4 4Q4V4 4YXDA 3P4QA 3VR9A 1VBB4 2HWB4 1AR64 3ABVA 4GB34 1NENA 1ZOYA 1KFYA 3J8F4 1HRV4 2ACZA 4Q4W4 1RUC4 4YSXA 1RHI4 3P4PA 2PY5A 2WS3A 1NCQD 3SFDA 1XHZA 1RVF4 3JBG4 3GQHA 2X5ID 1D4M4 3AE5A 3AEDA 1KF6A 3AE4A 2WP9A 1YQ4A 3AE1A 1NA1D 1PO24 5C3JA 1VBC4 1RUJ4 2WU2A 1ZP0A 1VBA4 3AECA 2RS34 2WDRA 2WU5A 1POV0 1OOPD 1R094 2EX3A 1R084 2R7FA 3AE8A 3SFEA 1PVC4 2PLV4 1RUG4 4YTMA 2PZSA 3AEFA 2RMU4 1PIV4 3AEBA 1RUF4 4YTNA 2RR14 2FBWA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1RUD 4;  1RUH 4;  1VBB 4;  2X5I D;  2R07 4;  1AR9 4;  1MQT D;  2HWB 4;  1AR6 4;  1NA1 D;  1VBD 4;  2RS5 4;  1PO2 4;  1HXS 4;  4GB3 4;  2R06 4;  1AR8 4;  1VBC 4;  1RUJ 4;  1VRH 4;  1BEV 4;  3J8F 4;  1HRV 4;  3JD7 4;  1K5M D;  4Q4W 4;  1EAH 4;  1RMU 4;  1VBA 4;  2RS1 4;  4PDW D;  2RS3 4;  4RHV 4;  1AR7 4;  1POV 0;  1OOP D;  1R09 4;  1RUC 4;  1RUI 4;  1Z7S 4;  1R08 4;  1ASJ 4;  1RHI 4;  4Q4X 4;  1COV 4;  2R04 4;  1HRI 4;  1NCQ D;  1VBE 4;  1AL2 4;  1PVC 4;  2HWC 4;  1PO1 4;  1H8T D;  1RUG 4;  2PLV 4;  1EV1 4;  1RUE 4;  1RVF 4;  2RM2 4;  3JBG 4;  2RMU 4;  1PIV 4;  4Q4V 4;  4Q4Y 4;  1RUF 4;  1D4M 4;  2RR1 4; 
#chains in the Genus database with same CATH topology
 4KX6 A;  1RUD 4;  3FI7 A;  4YSZ A;  1YQ3 A;  3P4R A;  3AE3 A;  3AEG A;  3P4S A;  1AR9 4;  1MQT D;  1NEK A;  1VBD 4;  2RS5 4;  1HXS 4;  2PYL A;  3VRB A;  1VRH 4;  2PYJ A;  3JD7 4;  1EAH 4;  4PDW D;  1XI1 A;  2PW9 A;  1AR7 4;  1Z7S 4;  3AE6 A;  2WQY A;  1ASJ 4;  1XHX A;  2B76 A;  2H88 A;  1COV 4;  2R04 4;  1VBE 4;  1AL2 4;  2HWC 4;  1RUE 4;  3VR8 A;  3AE9 A;  1RUH 4;  3AE2 A;  3AE7 A;  2R07 4;  3AEE A;  2WDV A;  2WDQ A;  2R06 4;  1AR8 4;  3CIR A;  1BEV 4;  3SUC A;  1K5M D;  2H89 A;  1RMU 4;  2RS1 4;  3GQK A;  4YTP A;  1RUI 4;  3AEA A;  4YT0 A;  5C2T A;  4Q4X 4;  3VRA A;  1HRI 4;  4YSY A;  1L0V A;  4RHV 4;  1PO1 4;  1H8T D;  1EV1 4;  2RM2 4;  4Q4Y 4;  4Q4V 4;  4YXD A;  3P4Q A;  3VR9 A;  1VBB 4;  2HWB 4;  1AR6 4;  3ABV A;  4GB3 4;  1NEN A;  1ZOY A;  1KFY A;  3J8F 4;  1HRV 4;  2ACZ A;  4Q4W 4;  1RUC 4;  4YSX A;  1RHI 4;  3P4P A;  2PY5 A;  2WS3 A;  1NCQ D;  3SFD A;  1XHZ A;  1RVF 4;  3JBG 4;  3GQH A;  2X5I D;  1D4M 4;  3AE5 A;  3AED A;  1KF6 A;  3AE4 A;  2WP9 A;  1YQ4 A;  3AE1 A;  1NA1 D;  1PO2 4;  5C3J A;  1VBC 4;  1RUJ 4;  2WU2 A;  1ZP0 A;  1VBA 4;  3AEC A;  2RS3 4;  2WDR A;  2WU5 A;  1POV 0;  1OOP D;  1R09 4;  2EX3 A;  1R08 4;  2R7F A;  3AE8 A;  3SFE A;  1PVC 4;  2PLV 4;  1RUG 4;  4YTM A;  2PZS A;  3AEF A;  2RMU 4;  1PIV 4;  3AEB A;  1RUF 4;  4YTN A;  2RR1 4;  2FBW A; 
#chains in the Genus database with same CATH homology
 1RUD 4;  1RUH 4;  1VBB 4;  2X5I D;  2R07 4;  1AR9 4;  1MQT D;  2HWB 4;  1AR6 4;  1NA1 D;  1VBD 4;  2RS5 4;  1PO2 4;  1HXS 4;  4GB3 4;  2R06 4;  1AR8 4;  1VBC 4;  1RUJ 4;  1VRH 4;  1BEV 4;  3J8F 4;  1HRV 4;  3JD7 4;  1K5M D;  4Q4W 4;  1EAH 4;  1RMU 4;  1VBA 4;  2RS1 4;  4PDW D;  2RS3 4;  4RHV 4;  1AR7 4;  1POV 0;  1OOP D;  1R09 4;  1RUC 4;  1RUI 4;  1Z7S 4;  1R08 4;  1ASJ 4;  1RHI 4;  4Q4X 4;  1COV 4;  2R04 4;  1HRI 4;  1NCQ D;  1VBE 4;  1AL2 4;  1PVC 4;  2HWC 4;  1PO1 4;  1H8T D;  1RUG 4;  2PLV 4;  1EV1 4;  1RUE 4;  1RVF 4;  2RM2 4;  3JBG 4;  2RMU 4;  1PIV 4;  4Q4V 4;  4Q4Y 4;  1RUF 4;  1D4M 4;  2RR1 4;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2HWC4

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations