1F9UA

Crystal structures of mutants reveal a signalling pathway for activation of the kinesin motor atpase
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
338
structure length
310
Chain Sequence
b'GNIRVYCRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSERRLRETQNIKKSLSCLGDVIHALGQPHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords KINESIN-LIKE PROTEIN KAR3
publication title A structural pathway for activation of the kinesin motor ATPase.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Contractile protein
total genus 109
structure length 310
sequence length 338
ec nomenclature
pdb deposition date 2000-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1f9uA00
1D1CA 1SDMA 3GBJA 1VFWA 2HEHA 1BG2A 2GRYA 4A14A 1Q0BA 2ZFKA 1LKXA 1RY6A 3PXNA 4PJLA 4A50A 3CNZA 2Q2YA 4LNUK 1BR2A 1BR4A 2X7CA 5GSZA 2X7DA 3H4SA 1BR1A 3X2TA 3B6VA 4ZCAA 3K5EA 1MMGA 2ZFMA 2Y65A 1F9VA 1D1AA 2WOGA 2GM1A 1VFVA 4PJJA 4AP0A 2Y5WA 3WRDA 2FMEA 2Q2ZA 4A28A 2UYMA 3BFNA 1FMVA 2KINA 4H1GA 3L1CA 2ZFJA 4E7ZA 3ZFCA 5LT0A 3KARA 5HLEA 1I6IA 3DC4A 4PFOA 3COBA 2MYSA 1D0YA 2X7EA 1G8XA 2IEHA 4BBGA 1F9TA 4E7SA 1V8JA 3B6UA 2FL6A 4ZHIA 3ZFDA 1I5SA 3T0QA 3KINA 4A1ZA 2PG2A 2XAEA 4HNAK 3K3BA 4AS7A 4BN2A 2UYIA 1FMWA 4UBFA 4ETPA 1VOMA 2ZFLA 4A51A 4PJNA 1CZ7A 1V8KA 4DBRA 3LREA 4Y05A 1MNEA 1VFZA 4ANJA 3U06A 2OWMA 2VVGA 5LT1A 1D0ZA 1VFXA 1MMDA 4DBQA 4FRZA 2X51A 1X88A 2ZFIA 2VB6A 5LT2A 1D1BA 4PK4A 1YRSA 1D0XA 2FL2A 1F9UA 2FKYA 4PJMA 3KENA 4GKRA 2VASA 3CJOA 3DCBA 4A5YA 3HQDA 3ZCWA 2XT3A 3L9HA 3NWNA 2G1QA 3WPNA 2X2RA 1MMAA 1MKJA 1T5CA 4BXNA 2V26A 5LT4A 1LVKA 1N6MA 1II6A 1KK7A 1GOJA 2NCDA 5LT3A 4PFPA 1MMNA 4B7BA 1F9WA
chains in the Genus database with same CATH superfamily
1D1CA 1SDMA 3GBJA 1VFWA 2HEHA 1BG2A 2GRYA 4A14A 1Q0BA 2ZFKA 1LKXA 1RY6A 3PXNA 4PJLA 4A50A 3CNZA 2Q2YA 4LNUK 1BR2A 1BR4A 2X7CA 5GSZA 2X7DA 3H4SA 1BR1A 3X2TA 3B6VA 4ZCAA 3K5EA 1MMGA 2ZFMA 2Y65A 1F9VA 1D1AA 2WOGA 2GM1A 1VFVA 4PJJA 4AP0A 2Y5WA 3WRDA 2FMEA 2Q2ZA 4A28A 2UYMA 3BFNA 1FMVA 2KINA 4H1GA 3L1CA 2ZFJA 2O0AA 4E7ZA 3ZFCA 5LT0A 3KARA 5HLEA 1I6IA 3DC4A 4PFOA 4ETPB 3COBA 2MYSA 1D0YA 2X7EA 1G8XA 2IEHA 4BBGA 1F9TA 4E7SA 1V8JA 3B6UA 2FL6A 4ZHIA 3ZFDA 1I5SA 3T0QA 3KINA 4A1ZA 2PG2A 2XAEA 4HNAK 3K3BA 4AS7A 4BN2A 2UYIA 1FMWA 4UBFA 4ETPA 1VOMA 2ZFLA 4A51A 4PJNA 1CZ7A 1V8KA 4DBRA 3LREA 4Y05A 1MNEA 1VFZA 4ANJA 3U06A 2OWMA 2VVGA 5LT1A 1D0ZA 1VFXA 1MMDA 4DBQA 4FRZA 2X51A 1X88A 2ZFIA 2VB6A 5LT2A 1D1BA 4PK4A 1YRSA 1D0XA 2FL2A 1F9UA 2FKYA 4PJMA 3KENA 4GKRA 2VASA 3CJOA 3DCBA 4A5YA 3HQDA 3ZCWA 2XT3A 3L9HA 3NWNA 2G1QA 3WPNA 2X2RA 1MMAA 1MKJA 1T5CA 4BXNA 2V26A 5LT4A 1LVKA 1N6MA 1II6A 1KK7A 1GOJA 2NCDA 5LT3A 4PFPA 1MMNA 4B7BA 1F9WA 4GKPA 4GKQA
chains in the Genus database with same CATH topology
1D1CA 1SDMA 3GBJA 1VFWA 2HEHA 1BG2A 2GRYA 4A14A 1Q0BA 2ZFKA 1LKXA 1RY6A 3PXNA 4PJLA 4A50A 3CNZA 2Q2YA 4LNUK 1BR2A 1BR4A 2X7CA 5GSZA 2X7DA 3H4SA 1BR1A 3X2TA 3B6VA 4ZCAA 3K5EA 1MMGA 2ZFMA 2Y65A 1F9VA 1D1AA 2WOGA 2GM1A 1VFVA 4PJJA 4AP0A 2Y5WA 3WRDA 2FMEA 2Q2ZA 4A28A 2UYMA 3BFNA 1FMVA 2KINA 4H1GA 3L1CA 2ZFJA 4E7ZA 3ZFCA 5LT0A 3KARA 5HLEA 1I6IA 3DC4A 4PFOA 3COBA 2MYSA 1D0YA 2X7EA 1G8XA 2IEHA 4BBGA 1F9TA 4E7SA 1V8JA 3B6UA 2FL6A 4ZHIA 3ZFDA 1I5SA 3T0QA 3KINA 4A1ZA 2PG2A 2XAEA 4HNAK 3K3BA 4AS7A 4BN2A 2UYIA 1FMWA 4UBFA 4ETPA 1VOMA 2ZFLA 4A51A 4PJNA 1CZ7A 1V8KA 4DBRA 3LREA 4Y05A 1MNEA 1VFZA 4ANJA 3U06A 2OWMA 2VVGA 5LT1A 1D0ZA 1VFXA 1MMDA 4DBQA 4FRZA 2X51A 1X88A 2ZFIA 2VB6A 5LT2A 1D1BA 4PK4A 1YRSA 1D0XA 2FL2A 1F9UA 2FKYA 4PJMA 3KENA 4GKRA 2VASA 3CJOA 3DCBA 4A5YA 3HQDA 3ZCWA 2XT3A 3L9HA 3NWNA 2G1QA 3WPNA 2X2RA 1MMAA 1MKJA 1T5CA 4BXNA 2V26A 5LT4A 1LVKA 1N6MA 1II6A 1KK7A 1GOJA 2NCDA 5LT3A 4PFPA 1MMNA 4B7BA 1F9WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D1C A;  1SDM A;  3GBJ A;  1VFW A;  2HEH A;  1BG2 A;  2GRY A;  4A14 A;  1Q0B A;  2ZFK A;  1LKX A;  1RY6 A;  3PXN A;  4PJL A;  4A50 A;  3CNZ A;  2Q2Y A;  4LNU K;  1BR2 A;  1BR4 A;  2X7C A;  5GSZ A;  2X7D A;  3H4S A;  1BR1 A;  3X2T A;  3B6V A;  4ZCA A;  3K5E A;  1MMG A;  2ZFM A;  2Y65 A;  1F9V A;  1D1A A;  2WOG A;  2GM1 A;  1VFV A;  4PJJ A;  4AP0 A;  2Y5W A;  3WRD A;  2FME A;  2Q2Z A;  4A28 A;  2UYM A;  3BFN A;  1FMV A;  2KIN A;  4H1G A;  3L1C A;  2ZFJ A;  4E7Z A;  3ZFC A;  5LT0 A;  3KAR A;  5HLE A;  1I6I A;  3DC4 A;  4PFO A;  3COB A;  2MYS A;  1D0Y A;  2X7E A;  1G8X A;  2IEH A;  4BBG A;  1F9T A;  4E7S A;  1V8J A;  3B6U A;  2FL6 A;  4ZHI A;  3ZFD A;  1I5S A;  3T0Q A;  3KIN A;  4A1Z A;  2PG2 A;  2XAE A;  4HNA K;  3K3B A;  4AS7 A;  4BN2 A;  2UYI A;  1FMW A;  4UBF A;  4ETP A;  1VOM A;  2ZFL A;  4A51 A;  4PJN A;  1CZ7 A;  1V8K A;  4DBR A;  3LRE A;  4Y05 A;  1MNE A;  1VFZ A;  4ANJ A;  3U06 A;  2OWM A;  2VVG A;  5LT1 A;  1D0Z A;  1VFX A;  1MMD A;  4DBQ A;  4FRZ A;  2X51 A;  1X88 A;  2ZFI A;  2VB6 A;  5LT2 A;  1D1B A;  4PK4 A;  1YRS A;  1D0X A;  2FL2 A;  1F9U A;  2FKY A;  4PJM A;  3KEN A;  4GKR A;  2VAS A;  3CJO A;  3DCB A;  4A5Y A;  3HQD A;  3ZCW A;  2XT3 A;  3L9H A;  3NWN A;  2G1Q A;  3WPN A;  2X2R A;  1MMA A;  1MKJ A;  1T5C A;  4BXN A;  2V26 A;  5LT4 A;  1LVK A;  1N6M A;  1II6 A;  1KK7 A;  1GOJ A;  2NCD A;  5LT3 A;  4PFP A;  1MMN A;  4B7B A;  1F9W A; 
#chains in the Genus database with same CATH topology
 1D1C A;  1SDM A;  3GBJ A;  1VFW A;  2HEH A;  1BG2 A;  2GRY A;  4A14 A;  1Q0B A;  2ZFK A;  1LKX A;  1RY6 A;  3PXN A;  4PJL A;  4A50 A;  3CNZ A;  2Q2Y A;  4LNU K;  1BR2 A;  1BR4 A;  2X7C A;  5GSZ A;  2X7D A;  3H4S A;  1BR1 A;  3X2T A;  3B6V A;  4ZCA A;  3K5E A;  1MMG A;  2ZFM A;  2Y65 A;  1F9V A;  1D1A A;  2WOG A;  2GM1 A;  1VFV A;  4PJJ A;  4AP0 A;  2Y5W A;  3WRD A;  2FME A;  2Q2Z A;  4A28 A;  2UYM A;  3BFN A;  1FMV A;  2KIN A;  4H1G A;  3L1C A;  2ZFJ A;  2O0A A;  4E7Z A;  3ZFC A;  5LT0 A;  3KAR A;  5HLE A;  1I6I A;  3DC4 A;  4PFO A;  4ETP B;  3COB A;  2MYS A;  1D0Y A;  2X7E A;  1G8X A;  2IEH A;  4BBG A;  1F9T A;  4E7S A;  1V8J A;  3B6U A;  2FL6 A;  4ZHI A;  3ZFD A;  1I5S A;  3T0Q A;  3KIN A;  4A1Z A;  2PG2 A;  2XAE A;  4HNA K;  3K3B A;  4AS7 A;  4BN2 A;  2UYI A;  1FMW A;  4UBF A;  4ETP A;  1VOM A;  2ZFL A;  4A51 A;  4PJN A;  1CZ7 A;  1V8K A;  4DBR A;  3LRE A;  4Y05 A;  1MNE A;  1VFZ A;  4ANJ A;  3U06 A;  2OWM A;  2VVG A;  5LT1 A;  1D0Z A;  1VFX A;  1MMD A;  4DBQ A;  4FRZ A;  2X51 A;  1X88 A;  2ZFI A;  2VB6 A;  5LT2 A;  1D1B A;  4PK4 A;  1YRS A;  1D0X A;  2FL2 A;  1F9U A;  2FKY A;  4PJM A;  3KEN A;  4GKR A;  2VAS A;  3CJO A;  3DCB A;  4A5Y A;  3HQD A;  3ZCW A;  2XT3 A;  3L9H A;  3NWN A;  2G1Q A;  3WPN A;  2X2R A;  1MMA A;  1MKJ A;  1T5C A;  4BXN A;  2V26 A;  5LT4 A;  1LVK A;  1N6M A;  1II6 A;  1KK7 A;  1GOJ A;  2NCD A;  5LT3 A;  4PFP A;  1MMN A;  4B7B A;  1F9W A;  4GKP A;  4GKQ A; 
#chains in the Genus database with same CATH homology
 1D1C A;  1SDM A;  3GBJ A;  1VFW A;  2HEH A;  1BG2 A;  2GRY A;  4A14 A;  1Q0B A;  2ZFK A;  1LKX A;  1RY6 A;  3PXN A;  4PJL A;  4A50 A;  3CNZ A;  2Q2Y A;  4LNU K;  1BR2 A;  1BR4 A;  2X7C A;  5GSZ A;  2X7D A;  3H4S A;  1BR1 A;  3X2T A;  3B6V A;  4ZCA A;  3K5E A;  1MMG A;  2ZFM A;  2Y65 A;  1F9V A;  1D1A A;  2WOG A;  2GM1 A;  1VFV A;  4PJJ A;  4AP0 A;  2Y5W A;  3WRD A;  2FME A;  2Q2Z A;  4A28 A;  2UYM A;  3BFN A;  1FMV A;  2KIN A;  4H1G A;  3L1C A;  2ZFJ A;  4E7Z A;  3ZFC A;  5LT0 A;  3KAR A;  5HLE A;  1I6I A;  3DC4 A;  4PFO A;  3COB A;  2MYS A;  1D0Y A;  2X7E A;  1G8X A;  2IEH A;  4BBG A;  1F9T A;  4E7S A;  1V8J A;  3B6U A;  2FL6 A;  4ZHI A;  3ZFD A;  1I5S A;  3T0Q A;  3KIN A;  4A1Z A;  2PG2 A;  2XAE A;  4HNA K;  3K3B A;  4AS7 A;  4BN2 A;  2UYI A;  1FMW A;  4UBF A;  4ETP A;  1VOM A;  2ZFL A;  4A51 A;  4PJN A;  1CZ7 A;  1V8K A;  4DBR A;  3LRE A;  4Y05 A;  1MNE A;  1VFZ A;  4ANJ A;  3U06 A;  2OWM A;  2VVG A;  5LT1 A;  1D0Z A;  1VFX A;  1MMD A;  4DBQ A;  4FRZ A;  2X51 A;  1X88 A;  2ZFI A;  2VB6 A;  5LT2 A;  1D1B A;  4PK4 A;  1YRS A;  1D0X A;  2FL2 A;  1F9U A;  2FKY A;  4PJM A;  3KEN A;  4GKR A;  2VAS A;  3CJO A;  3DCB A;  4A5Y A;  3HQD A;  3ZCW A;  2XT3 A;  3L9H A;  3NWN A;  2G1Q A;  3WPN A;  2X2R A;  1MMA A;  1MKJ A;  1T5C A;  4BXN A;  2V26 A;  5LT4 A;  1LVK A;  1N6M A;  1II6 A;  1KK7 A;  1GOJ A;  2NCD A;  5LT3 A;  4PFP A;  1MMN A;  4B7B A;  1F9W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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