1F9UA

Crystal structures of mutants reveal a signalling pathway for activation of the kinesin motor atpase
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
338
structure length
310
Chain Sequence
GNIRVYCRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSERRLRETQNIKKSLSCLGDVIHALGQPHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords KINESIN-LIKE PROTEIN KAR3
publication title A structural pathway for activation of the kinesin motor ATPase.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Contractile protein
total genus 109
structure length 310
sequence length 338
ec nomenclature
pdb deposition date 2000-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1f9uA00
2G1QA 1I6IA 3CNZA 1V8KA 4E7ZA 3ZFCA 3CJOA 2FL2A 4AP0A 1I5SA 4PJNA 3H4SA 4E7SA 4A50A 4PFOA 4LNUK 2HEHA 3B6UA 1T5CA 2V26A 1LKXA 2KINA 3ZCWA 2Q2ZA 3K5EA 3X2TA 2PG2A 4UBFA 3BFNA 1II6A 1FMVA 2IEHA 1Q0BA 4BXNA 4ZHIA 1YRSA 4PFPA 4BBGA 4DBRA 1SDMA 4DBQA 5LT0A 4PJLA 2UYMA 2NCDA 2GM1A 5LT2A 2GRYA 2OWMA 4ETPA 2WOGA 1N6MA 1GOJA 5LT3A 4PJMA 1FMWA 3KARA 3WRDA 3DCBA 1VFVA 1MMNA 4A28A 5GSZA 2XAEA 2UYIA 3L1CA 4A14A 4ANJA 1CZ7A 4ZCAA 2XT3A 3L9HA 4Y05A 4H1GA 2X7CA 2ZFKA 2Y5WA 1D1BA 4A1ZA 1G8XA 3U06A 4A51A 1D1AA 2X2RA 3KINA 1MMGA 2ZFIA 1KK7A 2MYSA 3WPNA 1BR2A 5LT1A 1BR4A 3ZFDA 3KENA 3HQDA 2FL6A 1F9TA 4GKRA 1D1CA 5HLEA 2VB6A 3PXNA 2ZFJA 1MMAA 3K3BA 4A5YA 2VVGA 1VFZA 4BN2A 2X51A 1D0XA 2X7DA 1D0ZA 3T0QA 1MMDA 2FMEA 4AS7A 1VFXA 1X88A 1MNEA 4FRZA 1F9VA 2FKYA 2ZFMA 3GBJA 1MKJA 1V8JA 3NWNA 5LT4A 3LREA 1F9UA 3COBA 1RY6A 1BR1A 3B6VA 2Y65A 4HNAK 3DC4A 4B7BA 1BG2A 2ZFLA 1LVKA 4PJJA 1D0YA 1VOMA 2X7EA 1VFWA 2Q2YA 4PK4A 1F9WA 2VASA
chains in the Genus database with same CATH superfamily
2G1QA 1I6IA 3CNZA 1V8KA 4E7ZA 3ZFCA 3CJOA 2FL2A 4GKPA 4GKQA 4AP0A 1I5SA 4PJNA 3H4SA 4E7SA 4A50A 4ETPB 4PFOA 4LNUK 2HEHA 3B6UA 1T5CA 2V26A 1LKXA 2KINA 3ZCWA 2Q2ZA 3K5EA 3X2TA 2PG2A 4UBFA 3BFNA 1II6A 1FMVA 2IEHA 1Q0BA 4BXNA 4ZHIA 1YRSA 4PFPA 4BBGA 4DBRA 1SDMA 4DBQA 5LT0A 4PJLA 2UYMA 2NCDA 2GM1A 5LT2A 2GRYA 2OWMA 4ETPA 2WOGA 1N6MA 1GOJA 5LT3A 4PJMA 1FMWA 3KARA 3WRDA 3DCBA 1VFVA 1MMNA 4A28A 5GSZA 2XAEA 2UYIA 3L1CA 4A14A 4ANJA 1CZ7A 4ZCAA 2XT3A 3L9HA 4Y05A 4H1GA 2X7CA 2ZFKA 2Y5WA 1D1BA 4A1ZA 1G8XA 3U06A 4A51A 1D1AA 2X2RA 3KINA 1MMGA 2ZFIA 1KK7A 2MYSA 3WPNA 1BR2A 5LT1A 1BR4A 3ZFDA 3KENA 3HQDA 2FL6A 1F9TA 4GKRA 2O0AA 1D1CA 5HLEA 2VB6A 3PXNA 2ZFJA 1MMAA 3K3BA 4A5YA 2VVGA 1VFZA 4BN2A 2X51A 1D0XA 2X7DA 1D0ZA 3T0QA 1MMDA 2FMEA 4AS7A 1VFXA 1X88A 1MNEA 4FRZA 1F9VA 2FKYA 2ZFMA 3GBJA 1MKJA 1V8JA 3NWNA 5LT4A 3LREA 1F9UA 3COBA 1RY6A 1BR1A 3B6VA 2Y65A 4HNAK 3DC4A 4B7BA 1BG2A 2ZFLA 1LVKA 4PJJA 1D0YA 1VOMA 2X7EA 1VFWA 2Q2YA 4PK4A 1F9WA 2VASA
chains in the Genus database with same CATH topology
2G1QA 1I6IA 3CNZA 1V8KA 4E7ZA 3ZFCA 3CJOA 2FL2A 4AP0A 1I5SA 4PJNA 3H4SA 4E7SA 4A50A 4PFOA 4LNUK 2HEHA 3B6UA 1T5CA 2V26A 1LKXA 2KINA 3ZCWA 2Q2ZA 3K5EA 3X2TA 2PG2A 4UBFA 3BFNA 1II6A 1FMVA 2IEHA 1Q0BA 4BXNA 4ZHIA 1YRSA 4PFPA 4BBGA 4DBRA 1SDMA 4DBQA 5LT0A 4PJLA 2UYMA 2NCDA 2GM1A 5LT2A 2GRYA 2OWMA 4ETPA 2WOGA 1N6MA 1GOJA 5LT3A 4PJMA 1FMWA 3KARA 3WRDA 3DCBA 1VFVA 1MMNA 4A28A 5GSZA 2XAEA 2UYIA 3L1CA 4A14A 4ANJA 1CZ7A 4ZCAA 2XT3A 3L9HA 4Y05A 4H1GA 2X7CA 2ZFKA 2Y5WA 1D1BA 4A1ZA 1G8XA 3U06A 4A51A 1D1AA 2X2RA 3KINA 1MMGA 2ZFIA 1KK7A 2MYSA 3WPNA 1BR2A 5LT1A 1BR4A 3ZFDA 3KENA 3HQDA 2FL6A 1F9TA 4GKRA 1D1CA 5HLEA 2VB6A 3PXNA 2ZFJA 1MMAA 3K3BA 4A5YA 2VVGA 1VFZA 4BN2A 2X51A 1D0XA 2X7DA 1D0ZA 3T0QA 1MMDA 2FMEA 4AS7A 1VFXA 1X88A 1MNEA 4FRZA 1F9VA 2FKYA 2ZFMA 3GBJA 1MKJA 1V8JA 3NWNA 5LT4A 3LREA 1F9UA 3COBA 1RY6A 1BR1A 3B6VA 2Y65A 4HNAK 3DC4A 4B7BA 1BG2A 2ZFLA 1LVKA 4PJJA 1D0YA 1VOMA 2X7EA 1VFWA 2Q2YA 4PK4A 1F9WA 2VASA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G1Q A;  1I6I A;  3CNZ A;  1V8K A;  4E7Z A;  3ZFC A;  3CJO A;  2FL2 A;  4AP0 A;  1I5S A;  4PJN A;  3H4S A;  4E7S A;  4A50 A;  4PFO A;  4LNU K;  2HEH A;  3B6U A;  1T5C A;  2V26 A;  1LKX A;  2KIN A;  3ZCW A;  2Q2Z A;  3K5E A;  3X2T A;  2PG2 A;  4UBF A;  3BFN A;  1II6 A;  1FMV A;  2IEH A;  1Q0B A;  4BXN A;  4ZHI A;  1YRS A;  4PFP A;  4BBG A;  4DBR A;  1SDM A;  4DBQ A;  5LT0 A;  4PJL A;  2UYM A;  2NCD A;  2GM1 A;  5LT2 A;  2GRY A;  2OWM A;  4ETP A;  2WOG A;  1N6M A;  1GOJ A;  5LT3 A;  4PJM A;  1FMW A;  3KAR A;  3WRD A;  3DCB A;  1VFV A;  1MMN A;  4A28 A;  5GSZ A;  2XAE A;  2UYI A;  3L1C A;  4A14 A;  4ANJ A;  1CZ7 A;  4ZCA A;  2XT3 A;  3L9H A;  4Y05 A;  4H1G A;  2X7C A;  2ZFK A;  2Y5W A;  1D1B A;  4A1Z A;  1G8X A;  3U06 A;  4A51 A;  1D1A A;  2X2R A;  3KIN A;  1MMG A;  2ZFI A;  1KK7 A;  2MYS A;  3WPN A;  1BR2 A;  5LT1 A;  1BR4 A;  3ZFD A;  3KEN A;  3HQD A;  2FL6 A;  1F9T A;  4GKR A;  1D1C A;  5HLE A;  2VB6 A;  3PXN A;  2ZFJ A;  1MMA A;  3K3B A;  4A5Y A;  2VVG A;  1VFZ A;  4BN2 A;  2X51 A;  1D0X A;  2X7D A;  1D0Z A;  3T0Q A;  1MMD A;  2FME A;  4AS7 A;  1VFX A;  1X88 A;  1MNE A;  4FRZ A;  1F9V A;  2FKY A;  2ZFM A;  3GBJ A;  1MKJ A;  1V8J A;  3NWN A;  5LT4 A;  3LRE A;  1F9U A;  3COB A;  1RY6 A;  1BR1 A;  3B6V A;  2Y65 A;  4HNA K;  3DC4 A;  4B7B A;  1BG2 A;  2ZFL A;  1LVK A;  4PJJ A;  1D0Y A;  1VOM A;  2X7E A;  1VFW A;  2Q2Y A;  4PK4 A;  1F9W A;  2VAS A; 
#chains in the Genus database with same CATH topology
 2G1Q A;  1I6I A;  3CNZ A;  1V8K A;  4E7Z A;  3ZFC A;  3CJO A;  2FL2 A;  4GKP A;  4GKQ A;  4AP0 A;  1I5S A;  4PJN A;  3H4S A;  4E7S A;  4A50 A;  4ETP B;  4PFO A;  4LNU K;  2HEH A;  3B6U A;  1T5C A;  2V26 A;  1LKX A;  2KIN A;  3ZCW A;  2Q2Z A;  3K5E A;  3X2T A;  2PG2 A;  4UBF A;  3BFN A;  1II6 A;  1FMV A;  2IEH A;  1Q0B A;  4BXN A;  4ZHI A;  1YRS A;  4PFP A;  4BBG A;  4DBR A;  1SDM A;  4DBQ A;  5LT0 A;  4PJL A;  2UYM A;  2NCD A;  2GM1 A;  5LT2 A;  2GRY A;  2OWM A;  4ETP A;  2WOG A;  1N6M A;  1GOJ A;  5LT3 A;  4PJM A;  1FMW A;  3KAR A;  3WRD A;  3DCB A;  1VFV A;  1MMN A;  4A28 A;  5GSZ A;  2XAE A;  2UYI A;  3L1C A;  4A14 A;  4ANJ A;  1CZ7 A;  4ZCA A;  2XT3 A;  3L9H A;  4Y05 A;  4H1G A;  2X7C A;  2ZFK A;  2Y5W A;  1D1B A;  4A1Z A;  1G8X A;  3U06 A;  4A51 A;  1D1A A;  2X2R A;  3KIN A;  1MMG A;  2ZFI A;  1KK7 A;  2MYS A;  3WPN A;  1BR2 A;  5LT1 A;  1BR4 A;  3ZFD A;  3KEN A;  3HQD A;  2FL6 A;  1F9T A;  4GKR A;  2O0A A;  1D1C A;  5HLE A;  2VB6 A;  3PXN A;  2ZFJ A;  1MMA A;  3K3B A;  4A5Y A;  2VVG A;  1VFZ A;  4BN2 A;  2X51 A;  1D0X A;  2X7D A;  1D0Z A;  3T0Q A;  1MMD A;  2FME A;  4AS7 A;  1VFX A;  1X88 A;  1MNE A;  4FRZ A;  1F9V A;  2FKY A;  2ZFM A;  3GBJ A;  1MKJ A;  1V8J A;  3NWN A;  5LT4 A;  3LRE A;  1F9U A;  3COB A;  1RY6 A;  1BR1 A;  3B6V A;  2Y65 A;  4HNA K;  3DC4 A;  4B7B A;  1BG2 A;  2ZFL A;  1LVK A;  4PJJ A;  1D0Y A;  1VOM A;  2X7E A;  1VFW A;  2Q2Y A;  4PK4 A;  1F9W A;  2VAS A; 
#chains in the Genus database with same CATH homology
 2G1Q A;  1I6I A;  3CNZ A;  1V8K A;  4E7Z A;  3ZFC A;  3CJO A;  2FL2 A;  4AP0 A;  1I5S A;  4PJN A;  3H4S A;  4E7S A;  4A50 A;  4PFO A;  4LNU K;  2HEH A;  3B6U A;  1T5C A;  2V26 A;  1LKX A;  2KIN A;  3ZCW A;  2Q2Z A;  3K5E A;  3X2T A;  2PG2 A;  4UBF A;  3BFN A;  1II6 A;  1FMV A;  2IEH A;  1Q0B A;  4BXN A;  4ZHI A;  1YRS A;  4PFP A;  4BBG A;  4DBR A;  1SDM A;  4DBQ A;  5LT0 A;  4PJL A;  2UYM A;  2NCD A;  2GM1 A;  5LT2 A;  2GRY A;  2OWM A;  4ETP A;  2WOG A;  1N6M A;  1GOJ A;  5LT3 A;  4PJM A;  1FMW A;  3KAR A;  3WRD A;  3DCB A;  1VFV A;  1MMN A;  4A28 A;  5GSZ A;  2XAE A;  2UYI A;  3L1C A;  4A14 A;  4ANJ A;  1CZ7 A;  4ZCA A;  2XT3 A;  3L9H A;  4Y05 A;  4H1G A;  2X7C A;  2ZFK A;  2Y5W A;  1D1B A;  4A1Z A;  1G8X A;  3U06 A;  4A51 A;  1D1A A;  2X2R A;  3KIN A;  1MMG A;  2ZFI A;  1KK7 A;  2MYS A;  3WPN A;  1BR2 A;  5LT1 A;  1BR4 A;  3ZFD A;  3KEN A;  3HQD A;  2FL6 A;  1F9T A;  4GKR A;  1D1C A;  5HLE A;  2VB6 A;  3PXN A;  2ZFJ A;  1MMA A;  3K3B A;  4A5Y A;  2VVG A;  1VFZ A;  4BN2 A;  2X51 A;  1D0X A;  2X7D A;  1D0Z A;  3T0Q A;  1MMD A;  2FME A;  4AS7 A;  1VFX A;  1X88 A;  1MNE A;  4FRZ A;  1F9V A;  2FKY A;  2ZFM A;  3GBJ A;  1MKJ A;  1V8J A;  3NWN A;  5LT4 A;  3LRE A;  1F9U A;  3COB A;  1RY6 A;  1BR1 A;  3B6V A;  2Y65 A;  4HNA K;  3DC4 A;  4B7B A;  1BG2 A;  2ZFL A;  1LVK A;  4PJJ A;  1D0Y A;  1VOM A;  2X7E A;  1VFW A;  2Q2Y A;  4PK4 A;  1F9W A;  2VAS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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