4HNAK

Kinesin motor domain in the adp-mg-alfx state in complex with tubulin and a darpin
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
333
structure length
333
Chain Sequence
AESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVSVNVELTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Tubulin alpha chain
publication title Structure of a kinesin-tubulin complex and implications for kinesin motility.
pubmed doi rcsb
source organism Artificial gene
molecule tags Motor protein
total genus 110
structure length 333
sequence length 333
ec nomenclature
pdb deposition date 2012-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 4hnaK00
3LREA 2XAEA 3DC4A 3L9HA 1MKJA 1D0ZA 4BXNA 2VASA 1D1BA 4AS7A 2G1QA 1RY6A 2X7DA 3K5EA 4E7SA 1D0XA 3BFNA 4A5YA 4PK4A 5LT2A 2GM1A 2X51A 2ZFJA 1BR2A 3NWNA 1V8KA 3L1CA 1MMGA 2FKYA 1BG2A 1F9UA 5GSZA 1VFZA 3KARA 1Q0BA 4BN2A 2FL2A 1N6MA 4H1GA 1MMDA 1G8XA 2X7CA 1MMNA 1FMWA 2ZFMA 1CZ7A 3GBJA 2Q2YA 4Y05A 5HLEA 4UBFA 3T0QA 1BR4A 2OWMA 1LVKA 3KINA 2IEHA 4PJMA 4E7ZA 4FRZA 3CJOA 2NCDA 2Y65A 2UYMA 3ZFDA 1MMAA 1VOMA 3X2TA 1LKXA 4DBRA 3COBA 3PXNA 2Y5WA 3K3BA 4BBGA 3WPNA 1V8JA 3U06A 4DBQA 1F9TA 2Q2ZA 2FMEA 1MNEA 1BR1A 4A50A 3B6UA 1VFXA 3B6VA 4A28A 4ZHIA 5LT1A 2MYSA 2WOGA 4ZCAA 2X2RA 1GOJA 2X7EA 4LNUK 1II6A 2XT3A 3H4SA 1SDMA 4HNAK 2PG2A 5LT0A 3CNZA 3ZCWA 3HQDA 4A51A 2UYIA 4PFOA 1T5CA 1VFWA 3KENA 2ZFLA 1VFVA 3ZFCA 3DCBA 1F9WA 1FMVA 4B7BA 1I5SA 4A14A 4AP0A 4ETPA 5LT3A 5LT4A 4GKRA 4PJLA 4PJJA 2GRYA 1YRSA 2HEHA 1X88A 2ZFKA 4PFPA 4ANJA 1D1AA 3WRDA 2V26A 1D1CA 2ZFIA 2KINA 2VVGA 2FL6A 1I6IA 4A1ZA 1KK7A 1F9VA 4PJNA 1D0YA 2VB6A
chains in the Genus database with same CATH superfamily
3LREA 2XAEA 3DC4A 3L9HA 1MKJA 1D0ZA 4BXNA 2VASA 1D1BA 4AS7A 2G1QA 1RY6A 2X7DA 3K5EA 4E7SA 1D0XA 3BFNA 4A5YA 4PK4A 5LT2A 2GM1A 2X51A 2ZFJA 1BR2A 3NWNA 1V8KA 3L1CA 1MMGA 2FKYA 1BG2A 1F9UA 5GSZA 1VFZA 3KARA 1Q0BA 4BN2A 2FL2A 1N6MA 4H1GA 1MMDA 1G8XA 2X7CA 1MMNA 4ETPB 1FMWA 2ZFMA 1CZ7A 3GBJA 2Q2YA 4Y05A 5HLEA 4UBFA 3T0QA 1BR4A 2OWMA 1LVKA 3KINA 2IEHA 4GKQA 4PJMA 4E7ZA 4FRZA 3CJOA 2NCDA 2Y65A 2UYMA 3ZFDA 1MMAA 1VOMA 3X2TA 1LKXA 4DBRA 3COBA 3PXNA 2Y5WA 3K3BA 4BBGA 3WPNA 1V8JA 3U06A 4DBQA 1F9TA 2Q2ZA 2FMEA 1MNEA 1BR1A 4A50A 3B6UA 1VFXA 3B6VA 4A28A 4ZHIA 5LT1A 2MYSA 2WOGA 4ZCAA 2X2RA 1GOJA 2X7EA 4LNUK 1II6A 2XT3A 3H4SA 1SDMA 4HNAK 2PG2A 5LT0A 3CNZA 3ZCWA 3HQDA 4A51A 2UYIA 4PFOA 1T5CA 1VFWA 3KENA 2ZFLA 1VFVA 3ZFCA 3DCBA 1F9WA 1FMVA 2O0AA 4B7BA 1I5SA 4A14A 4AP0A 4ETPA 5LT3A 5LT4A 4GKRA 4PJLA 4PJJA 2GRYA 1YRSA 4GKPA 2HEHA 1X88A 2ZFKA 4PFPA 4ANJA 1D1AA 3WRDA 2V26A 1D1CA 2ZFIA 2KINA 2VVGA 2FL6A 1I6IA 4A1ZA 1KK7A 1F9VA 4PJNA 1D0YA 2VB6A
chains in the Genus database with same CATH topology
3LREA 2XAEA 3DC4A 3L9HA 1MKJA 1D0ZA 4BXNA 2VASA 1D1BA 4AS7A 2G1QA 1RY6A 2X7DA 3K5EA 4E7SA 1D0XA 3BFNA 4A5YA 4PK4A 5LT2A 2GM1A 2X51A 2ZFJA 1BR2A 3NWNA 1V8KA 3L1CA 1MMGA 2FKYA 1BG2A 1F9UA 5GSZA 1VFZA 3KARA 1Q0BA 4BN2A 2FL2A 1N6MA 4H1GA 1MMDA 1G8XA 2X7CA 1MMNA 1FMWA 2ZFMA 1CZ7A 3GBJA 2Q2YA 4Y05A 5HLEA 4UBFA 3T0QA 1BR4A 2OWMA 1LVKA 3KINA 2IEHA 4PJMA 4E7ZA 4FRZA 3CJOA 2NCDA 2Y65A 2UYMA 3ZFDA 1MMAA 1VOMA 3X2TA 1LKXA 4DBRA 3COBA 3PXNA 2Y5WA 3K3BA 4BBGA 3WPNA 1V8JA 3U06A 4DBQA 1F9TA 2Q2ZA 2FMEA 1MNEA 1BR1A 4A50A 3B6UA 1VFXA 3B6VA 4A28A 4ZHIA 5LT1A 2MYSA 2WOGA 4ZCAA 2X2RA 1GOJA 2X7EA 4LNUK 1II6A 2XT3A 3H4SA 1SDMA 4HNAK 2PG2A 5LT0A 3CNZA 3ZCWA 3HQDA 4A51A 2UYIA 4PFOA 1T5CA 1VFWA 3KENA 2ZFLA 1VFVA 3ZFCA 3DCBA 1F9WA 1FMVA 4B7BA 1I5SA 4A14A 4AP0A 4ETPA 5LT3A 5LT4A 4GKRA 4PJLA 4PJJA 2GRYA 1YRSA 2HEHA 1X88A 2ZFKA 4PFPA 4ANJA 1D1AA 3WRDA 2V26A 1D1CA 2ZFIA 2KINA 2VVGA 2FL6A 1I6IA 4A1ZA 1KK7A 1F9VA 4PJNA 1D0YA 2VB6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LRE A;  2XAE A;  3DC4 A;  3L9H A;  1MKJ A;  1D0Z A;  4BXN A;  2VAS A;  1D1B A;  4AS7 A;  2G1Q A;  1RY6 A;  2X7D A;  3K5E A;  4E7S A;  1D0X A;  3BFN A;  4A5Y A;  4PK4 A;  5LT2 A;  2GM1 A;  2X51 A;  2ZFJ A;  1BR2 A;  3NWN A;  1V8K A;  3L1C A;  1MMG A;  2FKY A;  1BG2 A;  1F9U A;  5GSZ A;  1VFZ A;  3KAR A;  1Q0B A;  4BN2 A;  2FL2 A;  1N6M A;  4H1G A;  1MMD A;  1G8X A;  2X7C A;  1MMN A;  1FMW A;  2ZFM A;  1CZ7 A;  3GBJ A;  2Q2Y A;  4Y05 A;  5HLE A;  4UBF A;  3T0Q A;  1BR4 A;  2OWM A;  1LVK A;  3KIN A;  2IEH A;  4PJM A;  4E7Z A;  4FRZ A;  3CJO A;  2NCD A;  2Y65 A;  2UYM A;  3ZFD A;  1MMA A;  1VOM A;  3X2T A;  1LKX A;  4DBR A;  3COB A;  3PXN A;  2Y5W A;  3K3B A;  4BBG A;  3WPN A;  1V8J A;  3U06 A;  4DBQ A;  1F9T A;  2Q2Z A;  2FME A;  1MNE A;  1BR1 A;  4A50 A;  3B6U A;  1VFX A;  3B6V A;  4A28 A;  4ZHI A;  5LT1 A;  2MYS A;  2WOG A;  4ZCA A;  2X2R A;  1GOJ A;  2X7E A;  4LNU K;  1II6 A;  2XT3 A;  3H4S A;  1SDM A;  4HNA K;  2PG2 A;  5LT0 A;  3CNZ A;  3ZCW A;  3HQD A;  4A51 A;  2UYI A;  4PFO A;  1T5C A;  1VFW A;  3KEN A;  2ZFL A;  1VFV A;  3ZFC A;  3DCB A;  1F9W A;  1FMV A;  4B7B A;  1I5S A;  4A14 A;  4AP0 A;  4ETP A;  5LT3 A;  5LT4 A;  4GKR A;  4PJL A;  4PJJ A;  2GRY A;  1YRS A;  2HEH A;  1X88 A;  2ZFK A;  4PFP A;  4ANJ A;  1D1A A;  3WRD A;  2V26 A;  1D1C A;  2ZFI A;  2KIN A;  2VVG A;  2FL6 A;  1I6I A;  4A1Z A;  1KK7 A;  1F9V A;  4PJN A;  1D0Y A;  2VB6 A; 
#chains in the Genus database with same CATH topology
 3LRE A;  2XAE A;  3DC4 A;  3L9H A;  1MKJ A;  1D0Z A;  4BXN A;  2VAS A;  1D1B A;  4AS7 A;  2G1Q A;  1RY6 A;  2X7D A;  3K5E A;  4E7S A;  1D0X A;  3BFN A;  4A5Y A;  4PK4 A;  5LT2 A;  2GM1 A;  2X51 A;  2ZFJ A;  1BR2 A;  3NWN A;  1V8K A;  3L1C A;  1MMG A;  2FKY A;  1BG2 A;  1F9U A;  5GSZ A;  1VFZ A;  3KAR A;  1Q0B A;  4BN2 A;  2FL2 A;  1N6M A;  4H1G A;  1MMD A;  1G8X A;  2X7C A;  1MMN A;  4ETP B;  1FMW A;  2ZFM A;  1CZ7 A;  3GBJ A;  2Q2Y A;  4Y05 A;  5HLE A;  4UBF A;  3T0Q A;  1BR4 A;  2OWM A;  1LVK A;  3KIN A;  2IEH A;  4GKQ A;  4PJM A;  4E7Z A;  4FRZ A;  3CJO A;  2NCD A;  2Y65 A;  2UYM A;  3ZFD A;  1MMA A;  1VOM A;  3X2T A;  1LKX A;  4DBR A;  3COB A;  3PXN A;  2Y5W A;  3K3B A;  4BBG A;  3WPN A;  1V8J A;  3U06 A;  4DBQ A;  1F9T A;  2Q2Z A;  2FME A;  1MNE A;  1BR1 A;  4A50 A;  3B6U A;  1VFX A;  3B6V A;  4A28 A;  4ZHI A;  5LT1 A;  2MYS A;  2WOG A;  4ZCA A;  2X2R A;  1GOJ A;  2X7E A;  4LNU K;  1II6 A;  2XT3 A;  3H4S A;  1SDM A;  4HNA K;  2PG2 A;  5LT0 A;  3CNZ A;  3ZCW A;  3HQD A;  4A51 A;  2UYI A;  4PFO A;  1T5C A;  1VFW A;  3KEN A;  2ZFL A;  1VFV A;  3ZFC A;  3DCB A;  1F9W A;  1FMV A;  2O0A A;  4B7B A;  1I5S A;  4A14 A;  4AP0 A;  4ETP A;  5LT3 A;  5LT4 A;  4GKR A;  4PJL A;  4PJJ A;  2GRY A;  1YRS A;  4GKP A;  2HEH A;  1X88 A;  2ZFK A;  4PFP A;  4ANJ A;  1D1A A;  3WRD A;  2V26 A;  1D1C A;  2ZFI A;  2KIN A;  2VVG A;  2FL6 A;  1I6I A;  4A1Z A;  1KK7 A;  1F9V A;  4PJN A;  1D0Y A;  2VB6 A; 
#chains in the Genus database with same CATH homology
 3LRE A;  2XAE A;  3DC4 A;  3L9H A;  1MKJ A;  1D0Z A;  4BXN A;  2VAS A;  1D1B A;  4AS7 A;  2G1Q A;  1RY6 A;  2X7D A;  3K5E A;  4E7S A;  1D0X A;  3BFN A;  4A5Y A;  4PK4 A;  5LT2 A;  2GM1 A;  2X51 A;  2ZFJ A;  1BR2 A;  3NWN A;  1V8K A;  3L1C A;  1MMG A;  2FKY A;  1BG2 A;  1F9U A;  5GSZ A;  1VFZ A;  3KAR A;  1Q0B A;  4BN2 A;  2FL2 A;  1N6M A;  4H1G A;  1MMD A;  1G8X A;  2X7C A;  1MMN A;  1FMW A;  2ZFM A;  1CZ7 A;  3GBJ A;  2Q2Y A;  4Y05 A;  5HLE A;  4UBF A;  3T0Q A;  1BR4 A;  2OWM A;  1LVK A;  3KIN A;  2IEH A;  4PJM A;  4E7Z A;  4FRZ A;  3CJO A;  2NCD A;  2Y65 A;  2UYM A;  3ZFD A;  1MMA A;  1VOM A;  3X2T A;  1LKX A;  4DBR A;  3COB A;  3PXN A;  2Y5W A;  3K3B A;  4BBG A;  3WPN A;  1V8J A;  3U06 A;  4DBQ A;  1F9T A;  2Q2Z A;  2FME A;  1MNE A;  1BR1 A;  4A50 A;  3B6U A;  1VFX A;  3B6V A;  4A28 A;  4ZHI A;  5LT1 A;  2MYS A;  2WOG A;  4ZCA A;  2X2R A;  1GOJ A;  2X7E A;  4LNU K;  1II6 A;  2XT3 A;  3H4S A;  1SDM A;  4HNA K;  2PG2 A;  5LT0 A;  3CNZ A;  3ZCW A;  3HQD A;  4A51 A;  2UYI A;  4PFO A;  1T5C A;  1VFW A;  3KEN A;  2ZFL A;  1VFV A;  3ZFC A;  3DCB A;  1F9W A;  1FMV A;  4B7B A;  1I5S A;  4A14 A;  4AP0 A;  4ETP A;  5LT3 A;  5LT4 A;  4GKR A;  4PJL A;  4PJJ A;  2GRY A;  1YRS A;  2HEH A;  1X88 A;  2ZFK A;  4PFP A;  4ANJ A;  1D1A A;  3WRD A;  2V26 A;  1D1C A;  2ZFI A;  2KIN A;  2VVG A;  2FL6 A;  1I6I A;  4A1Z A;  1KK7 A;  1F9V A;  4PJN A;  1D0Y A;  2VB6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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