5LT2A

Nucleotide-free kinesin-1 motor domain, p1 crystal form
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
319
structure length
314
Chain Sequence
ESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural switch of nucleotide-free kinesin.
pubmed doi rcsb
molecule tags Motor protein
source organism Homo sapiens
molecule keywords Kinesin-like protein
total genus 98
structure length 314
sequence length 319
chains with identical sequence B, C, D, E, K
ec nomenclature
pdb deposition date 2016-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 5lt2A00
1RY6A 2ZFKA 4A28A 3X2TA 2OWMA 4FRZA 3U06A 2FL2A 2HEHA 3L9HA 2ZFMA 3LREA 1KK7A 1BR4A 3K5EA 2Q2YA 1X88A 3KINA 4UBFA 1FMWA 5LT3A 3PXNA 1V8JA 3GBJA 4A5YA 1VFXA 1VFZA 4BN2A 4PJJA 2X51A 2X7CA 3NWNA 4HNAK 3WPNA 2GRYA 1CZ7A 3K3BA 4E7ZA 1D1AA 2ZFLA 5LT2A 4A1ZA 4LNUK 3T0QA 4A50A 4ZHIA 3ZCWA 1Q0BA 4DBQA 3BFNA 2Q2ZA 2FMEA 1II6A 2ZFIA 1GOJA 1FMVA 5LT0A 2VVGA 4A14A 4A51A 1VOMA 4PFOA 4PK4A 2VB6A 3H4SA 5LT1A 2FL6A 2PG2A 1VFWA 1MNEA 1BG2A 5GSZA 4AP0A 4ANJA 2XT3A 1VFVA 1I5SA 1BR1A 1MMDA 1V8KA 2UYMA 4B7BA 3WRDA 2XAEA 4PJLA 1G8XA 4BXNA 4Y05A 3ZFDA 2KINA 5LT4A 4ETPA 3KENA 3CJOA 1SDMA 2Y5WA 2X7EA 3KARA 1D0YA 1I6IA 1MMAA 1T5CA 1D1BA 1LKXA 2GM1A 4H1GA 4E7SA 4PJMA 2FKYA 2WOGA 1D0XA 4PFPA 4PJNA 3B6UA 2ZFJA 4DBRA 1MMNA 2X2RA 2MYSA 3L1CA 1D1CA 1LVKA 2NCDA 2Y65A 4ZCAA 2X7DA 3DCBA 3ZFCA 4BBGA 1N6MA 1MKJA 3B6VA 1YRSA 3CNZA 4AS7A 2V26A 1F9TA 3DC4A 2G1QA 1BR2A 1F9UA 5HLEA 2UYIA 1MMGA 1D0ZA 2IEHA 4GKRA 3COBA 3HQDA 2VASA 1F9WA 1F9VA
chains in the Genus database with same CATH superfamily
1RY6A 2ZFKA 4GKPA 4A28A 3X2TA 2OWMA 4FRZA 3U06A 2FL2A 2HEHA 3L9HA 2ZFMA 3LREA 1KK7A 1BR4A 3K5EA 2Q2YA 1X88A 3KINA 4UBFA 1FMWA 5LT3A 3PXNA 1V8JA 3GBJA 4A5YA 1VFXA 1VFZA 4BN2A 4PJJA 2X51A 2X7CA 3NWNA 4HNAK 3WPNA 2GRYA 1CZ7A 3K3BA 4E7ZA 1D1AA 2ZFLA 5LT2A 4A1ZA 4LNUK 3T0QA 4A50A 4ZHIA 3ZCWA 1Q0BA 4DBQA 3BFNA 2Q2ZA 2FMEA 1II6A 2ZFIA 1GOJA 1FMVA 5LT0A 2VVGA 4A14A 4A51A 1VOMA 4PFOA 4PK4A 2VB6A 3H4SA 5LT1A 2FL6A 2PG2A 1VFWA 1MNEA 1BG2A 5GSZA 4AP0A 4ANJA 2XT3A 1VFVA 1I5SA 1BR1A 4ETPB 1MMDA 1V8KA 2UYMA 4B7BA 3WRDA 2XAEA 4PJLA 1G8XA 4BXNA 4Y05A 3ZFDA 2KINA 5LT4A 4ETPA 3KENA 3CJOA 1SDMA 4GKQA 2Y5WA 2X7EA 3KARA 1D0YA 1I6IA 1MMAA 1T5CA 1D1BA 1LKXA 2GM1A 4H1GA 4E7SA 4PJMA 2FKYA 2WOGA 1D0XA 4PFPA 4PJNA 3B6UA 2ZFJA 4DBRA 1MMNA 2X2RA 2MYSA 3L1CA 1D1CA 1LVKA 2NCDA 2Y65A 4ZCAA 2X7DA 3DCBA 3ZFCA 4BBGA 1N6MA 1MKJA 3B6VA 1YRSA 2O0AA 3CNZA 4AS7A 2V26A 1F9TA 3DC4A 2G1QA 1BR2A 1F9UA 5HLEA 2UYIA 1MMGA 1D0ZA 2IEHA 4GKRA 3COBA 3HQDA 2VASA 1F9WA 1F9VA
chains in the Genus database with same CATH topology
1RY6A 2ZFKA 4A28A 3X2TA 2OWMA 4FRZA 3U06A 2FL2A 2HEHA 3L9HA 2ZFMA 3LREA 1KK7A 1BR4A 3K5EA 2Q2YA 1X88A 3KINA 4UBFA 1FMWA 5LT3A 3PXNA 1V8JA 3GBJA 4A5YA 1VFXA 1VFZA 4BN2A 4PJJA 2X51A 2X7CA 3NWNA 4HNAK 3WPNA 2GRYA 1CZ7A 3K3BA 4E7ZA 1D1AA 2ZFLA 5LT2A 4A1ZA 4LNUK 3T0QA 4A50A 4ZHIA 3ZCWA 1Q0BA 4DBQA 3BFNA 2Q2ZA 2FMEA 1II6A 2ZFIA 1GOJA 1FMVA 5LT0A 2VVGA 4A14A 4A51A 1VOMA 4PFOA 4PK4A 2VB6A 3H4SA 5LT1A 2FL6A 2PG2A 1VFWA 1MNEA 1BG2A 5GSZA 4AP0A 4ANJA 2XT3A 1VFVA 1I5SA 1BR1A 1MMDA 1V8KA 2UYMA 4B7BA 3WRDA 2XAEA 4PJLA 1G8XA 4BXNA 4Y05A 3ZFDA 2KINA 5LT4A 4ETPA 3KENA 3CJOA 1SDMA 2Y5WA 2X7EA 3KARA 1D0YA 1I6IA 1MMAA 1T5CA 1D1BA 1LKXA 2GM1A 4H1GA 4E7SA 4PJMA 2FKYA 2WOGA 1D0XA 4PFPA 4PJNA 3B6UA 2ZFJA 4DBRA 1MMNA 2X2RA 2MYSA 3L1CA 1D1CA 1LVKA 2NCDA 2Y65A 4ZCAA 2X7DA 3DCBA 3ZFCA 4BBGA 1N6MA 1MKJA 3B6VA 1YRSA 3CNZA 4AS7A 2V26A 1F9TA 3DC4A 2G1QA 1BR2A 1F9UA 5HLEA 2UYIA 1MMGA 1D0ZA 2IEHA 4GKRA 3COBA 3HQDA 2VASA 1F9WA 1F9VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RY6 A;  2ZFK A;  4A28 A;  3X2T A;  2OWM A;  4FRZ A;  3U06 A;  2FL2 A;  2HEH A;  3L9H A;  2ZFM A;  3LRE A;  1KK7 A;  1BR4 A;  3K5E A;  2Q2Y A;  1X88 A;  3KIN A;  4UBF A;  1FMW A;  5LT3 A;  3PXN A;  1V8J A;  3GBJ A;  4A5Y A;  1VFX A;  1VFZ A;  4BN2 A;  4PJJ A;  2X51 A;  2X7C A;  3NWN A;  4HNA K;  3WPN A;  2GRY A;  1CZ7 A;  3K3B A;  4E7Z A;  1D1A A;  2ZFL A;  5LT2 A;  4A1Z A;  4LNU K;  3T0Q A;  4A50 A;  4ZHI A;  3ZCW A;  1Q0B A;  4DBQ A;  3BFN A;  2Q2Z A;  2FME A;  1II6 A;  2ZFI A;  1GOJ A;  1FMV A;  5LT0 A;  2VVG A;  4A14 A;  4A51 A;  1VOM A;  4PFO A;  4PK4 A;  2VB6 A;  3H4S A;  5LT1 A;  2FL6 A;  2PG2 A;  1VFW A;  1MNE A;  1BG2 A;  5GSZ A;  4AP0 A;  4ANJ A;  2XT3 A;  1VFV A;  1I5S A;  1BR1 A;  1MMD A;  1V8K A;  2UYM A;  4B7B A;  3WRD A;  2XAE A;  4PJL A;  1G8X A;  4BXN A;  4Y05 A;  3ZFD A;  2KIN A;  5LT4 A;  4ETP A;  3KEN A;  3CJO A;  1SDM A;  2Y5W A;  2X7E A;  3KAR A;  1D0Y A;  1I6I A;  1MMA A;  1T5C A;  1D1B A;  1LKX A;  2GM1 A;  4H1G A;  4E7S A;  4PJM A;  2FKY A;  2WOG A;  1D0X A;  4PFP A;  4PJN A;  3B6U A;  2ZFJ A;  4DBR A;  1MMN A;  2X2R A;  2MYS A;  3L1C A;  1D1C A;  1LVK A;  2NCD A;  2Y65 A;  4ZCA A;  2X7D A;  3DCB A;  3ZFC A;  4BBG A;  1N6M A;  1MKJ A;  3B6V A;  1YRS A;  3CNZ A;  4AS7 A;  2V26 A;  1F9T A;  3DC4 A;  2G1Q A;  1BR2 A;  1F9U A;  5HLE A;  2UYI A;  1MMG A;  1D0Z A;  2IEH A;  4GKR A;  3COB A;  3HQD A;  2VAS A;  1F9W A;  1F9V A; 
#chains in the Genus database with same CATH topology
 1RY6 A;  2ZFK A;  4GKP A;  4A28 A;  3X2T A;  2OWM A;  4FRZ A;  3U06 A;  2FL2 A;  2HEH A;  3L9H A;  2ZFM A;  3LRE A;  1KK7 A;  1BR4 A;  3K5E A;  2Q2Y A;  1X88 A;  3KIN A;  4UBF A;  1FMW A;  5LT3 A;  3PXN A;  1V8J A;  3GBJ A;  4A5Y A;  1VFX A;  1VFZ A;  4BN2 A;  4PJJ A;  2X51 A;  2X7C A;  3NWN A;  4HNA K;  3WPN A;  2GRY A;  1CZ7 A;  3K3B A;  4E7Z A;  1D1A A;  2ZFL A;  5LT2 A;  4A1Z A;  4LNU K;  3T0Q A;  4A50 A;  4ZHI A;  3ZCW A;  1Q0B A;  4DBQ A;  3BFN A;  2Q2Z A;  2FME A;  1II6 A;  2ZFI A;  1GOJ A;  1FMV A;  5LT0 A;  2VVG A;  4A14 A;  4A51 A;  1VOM A;  4PFO A;  4PK4 A;  2VB6 A;  3H4S A;  5LT1 A;  2FL6 A;  2PG2 A;  1VFW A;  1MNE A;  1BG2 A;  5GSZ A;  4AP0 A;  4ANJ A;  2XT3 A;  1VFV A;  1I5S A;  1BR1 A;  4ETP B;  1MMD A;  1V8K A;  2UYM A;  4B7B A;  3WRD A;  2XAE A;  4PJL A;  1G8X A;  4BXN A;  4Y05 A;  3ZFD A;  2KIN A;  5LT4 A;  4ETP A;  3KEN A;  3CJO A;  1SDM A;  4GKQ A;  2Y5W A;  2X7E A;  3KAR A;  1D0Y A;  1I6I A;  1MMA A;  1T5C A;  1D1B A;  1LKX A;  2GM1 A;  4H1G A;  4E7S A;  4PJM A;  2FKY A;  2WOG A;  1D0X A;  4PFP A;  4PJN A;  3B6U A;  2ZFJ A;  4DBR A;  1MMN A;  2X2R A;  2MYS A;  3L1C A;  1D1C A;  1LVK A;  2NCD A;  2Y65 A;  4ZCA A;  2X7D A;  3DCB A;  3ZFC A;  4BBG A;  1N6M A;  1MKJ A;  3B6V A;  1YRS A;  2O0A A;  3CNZ A;  4AS7 A;  2V26 A;  1F9T A;  3DC4 A;  2G1Q A;  1BR2 A;  1F9U A;  5HLE A;  2UYI A;  1MMG A;  1D0Z A;  2IEH A;  4GKR A;  3COB A;  3HQD A;  2VAS A;  1F9W A;  1F9V A; 
#chains in the Genus database with same CATH homology
 1RY6 A;  2ZFK A;  4A28 A;  3X2T A;  2OWM A;  4FRZ A;  3U06 A;  2FL2 A;  2HEH A;  3L9H A;  2ZFM A;  3LRE A;  1KK7 A;  1BR4 A;  3K5E A;  2Q2Y A;  1X88 A;  3KIN A;  4UBF A;  1FMW A;  5LT3 A;  3PXN A;  1V8J A;  3GBJ A;  4A5Y A;  1VFX A;  1VFZ A;  4BN2 A;  4PJJ A;  2X51 A;  2X7C A;  3NWN A;  4HNA K;  3WPN A;  2GRY A;  1CZ7 A;  3K3B A;  4E7Z A;  1D1A A;  2ZFL A;  5LT2 A;  4A1Z A;  4LNU K;  3T0Q A;  4A50 A;  4ZHI A;  3ZCW A;  1Q0B A;  4DBQ A;  3BFN A;  2Q2Z A;  2FME A;  1II6 A;  2ZFI A;  1GOJ A;  1FMV A;  5LT0 A;  2VVG A;  4A14 A;  4A51 A;  1VOM A;  4PFO A;  4PK4 A;  2VB6 A;  3H4S A;  5LT1 A;  2FL6 A;  2PG2 A;  1VFW A;  1MNE A;  1BG2 A;  5GSZ A;  4AP0 A;  4ANJ A;  2XT3 A;  1VFV A;  1I5S A;  1BR1 A;  1MMD A;  1V8K A;  2UYM A;  4B7B A;  3WRD A;  2XAE A;  4PJL A;  1G8X A;  4BXN A;  4Y05 A;  3ZFD A;  2KIN A;  5LT4 A;  4ETP A;  3KEN A;  3CJO A;  1SDM A;  2Y5W A;  2X7E A;  3KAR A;  1D0Y A;  1I6I A;  1MMA A;  1T5C A;  1D1B A;  1LKX A;  2GM1 A;  4H1G A;  4E7S A;  4PJM A;  2FKY A;  2WOG A;  1D0X A;  4PFP A;  4PJN A;  3B6U A;  2ZFJ A;  4DBR A;  1MMN A;  2X2R A;  2MYS A;  3L1C A;  1D1C A;  1LVK A;  2NCD A;  2Y65 A;  4ZCA A;  2X7D A;  3DCB A;  3ZFC A;  4BBG A;  1N6M A;  1MKJ A;  3B6V A;  1YRS A;  3CNZ A;  4AS7 A;  2V26 A;  1F9T A;  3DC4 A;  2G1Q A;  1BR2 A;  1F9U A;  5HLE A;  2UYI A;  1MMG A;  1D0Z A;  2IEH A;  4GKR A;  3COB A;  3HQD A;  2VAS A;  1F9W A;  1F9V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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