1II6A

Crystal structure of the mitotic kinesin eg5 in complex with mg-adp.
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
350
structure length
340
Chain Sequence
GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSERAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords KINESIN-RELATED MOTOR PROTEIN Eg5
publication title Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Cell cycle
total genus 106
structure length 340
sequence length 350
chains with identical sequence B
ec nomenclature
pdb deposition date 2001-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1ii6A00
1I6IA 1VFZA 1D1AA 3COBA 1MKJA 2FL6A 3DC4A 1MMGA 5LT0A 2FMEA 3KARA 2X2RA 1MMAA 5LT2A 4A1ZA 3HQDA 4ZCAA 1BG2A 1MMDA 1F9WA 4AP0A 4A51A 3U06A 1MNEA 1D0YA 2VB6A 5GSZA 2WOGA 4BBGA 4E7ZA 2FKYA 1F9TA 3L1CA 3X2TA 1II6A 4A5YA 2GRYA 4ZHIA 2FL2A 1BR4A 1BR1A 1FMWA 2X7DA 2Q2ZA 1T5CA 1VFXA 3DCBA 3LREA 4HNAK 1N6MA 2VASA 2X7CA 1MMNA 4PJJA 2X51A 2ZFIA 3B6UA 1SDMA 1V8JA 1I5SA 2HEHA 3GBJA 1D1CA 2ZFJA 3NWNA 4LNUK 3K5EA 1D0ZA 4H1GA 4DBRA 1LVKA 2ZFLA 1YRSA 2G1QA 2V26A 2KINA 1F9UA 2Y65A 1VOMA 4AS7A 3CNZA 3ZCWA 2GM1A 4GKRA 5HLEA 3BFNA 5LT3A 2OWMA 3H4SA 3WRDA 4Y05A 2MYSA 4UBFA 4PJMA 1KK7A 4BN2A 3KENA 4ANJA 5LT4A 2PG2A 4B7BA 1CZ7A 4FRZA 1VFVA 4PJNA 4A28A 1D0XA 2UYIA 3WPNA 3CJOA 2ZFKA 2X7EA 3PXNA 1G8XA 2XT3A 4PJLA 5LT1A 4E7SA 2UYMA 3KINA 2Y5WA 1Q0BA 3K3BA 4BXNA 3ZFCA 3B6VA 2NCDA 1VFWA 2XAEA 4A14A 2VVGA 4PFOA 4ETPA 4DBQA 1X88A 1F9VA 1D1BA 1RY6A 4PK4A 2Q2YA 3L9HA 1BR2A 1LKXA 3T0QA 2ZFMA 2IEHA 1GOJA 1V8KA 1FMVA 4PFPA 4A50A 3ZFDA
chains in the Genus database with same CATH superfamily
4GKPA 1I6IA 4GKQA 1VFZA 1D1AA 3COBA 1MKJA 2FL6A 3DC4A 1MMGA 5LT0A 2FMEA 3KARA 2X2RA 1MMAA 5LT2A 4A1ZA 3HQDA 4ZCAA 1BG2A 1MMDA 1F9WA 4AP0A 4A51A 3U06A 1MNEA 1D0YA 2VB6A 5GSZA 2WOGA 4BBGA 4E7ZA 2FKYA 1F9TA 3L1CA 3X2TA 4ETPB 1II6A 4A5YA 2GRYA 4ZHIA 2FL2A 1BR4A 1BR1A 1FMWA 2X7DA 2Q2ZA 1T5CA 1VFXA 3DCBA 3LREA 4HNAK 1N6MA 2VASA 2X7CA 1MMNA 4PJJA 2X51A 2ZFIA 3B6UA 1SDMA 1V8JA 1I5SA 2HEHA 3GBJA 1D1CA 2ZFJA 3NWNA 4LNUK 3K5EA 1D0ZA 4H1GA 4DBRA 1LVKA 2ZFLA 1YRSA 2G1QA 2V26A 2KINA 1F9UA 2Y65A 1VOMA 4AS7A 3CNZA 3ZCWA 2GM1A 4GKRA 5HLEA 3BFNA 5LT3A 2OWMA 3H4SA 3WRDA 4Y05A 2MYSA 4UBFA 4PJMA 1KK7A 4BN2A 3KENA 4ANJA 5LT4A 2PG2A 4B7BA 1CZ7A 4FRZA 1VFVA 4PJNA 4A28A 1D0XA 2UYIA 3WPNA 3CJOA 2ZFKA 2X7EA 3PXNA 1G8XA 2XT3A 4PJLA 5LT1A 4E7SA 2UYMA 3KINA 2Y5WA 1Q0BA 3K3BA 4BXNA 3ZFCA 3B6VA 2NCDA 1VFWA 2XAEA 4A14A 2VVGA 2O0AA 4PFOA 4ETPA 4DBQA 1X88A 1F9VA 1D1BA 1RY6A 4PK4A 2Q2YA 3L9HA 1BR2A 1LKXA 3T0QA 2ZFMA 2IEHA 1GOJA 1V8KA 1FMVA 4PFPA 4A50A 3ZFDA
chains in the Genus database with same CATH topology
1I6IA 1VFZA 1D1AA 3COBA 1MKJA 2FL6A 3DC4A 1MMGA 5LT0A 2FMEA 3KARA 2X2RA 1MMAA 5LT2A 4A1ZA 3HQDA 4ZCAA 1BG2A 1MMDA 1F9WA 4AP0A 4A51A 3U06A 1MNEA 1D0YA 2VB6A 5GSZA 2WOGA 4BBGA 4E7ZA 2FKYA 1F9TA 3L1CA 3X2TA 1II6A 4A5YA 2GRYA 4ZHIA 2FL2A 1BR4A 1BR1A 1FMWA 2X7DA 2Q2ZA 1T5CA 1VFXA 3DCBA 3LREA 4HNAK 1N6MA 2VASA 2X7CA 1MMNA 4PJJA 2X51A 2ZFIA 3B6UA 1SDMA 1V8JA 1I5SA 2HEHA 3GBJA 1D1CA 2ZFJA 3NWNA 4LNUK 3K5EA 1D0ZA 4H1GA 4DBRA 1LVKA 2ZFLA 1YRSA 2G1QA 2V26A 2KINA 1F9UA 2Y65A 1VOMA 4AS7A 3CNZA 3ZCWA 2GM1A 4GKRA 5HLEA 3BFNA 5LT3A 2OWMA 3H4SA 3WRDA 4Y05A 2MYSA 4UBFA 4PJMA 1KK7A 4BN2A 3KENA 4ANJA 5LT4A 2PG2A 4B7BA 1CZ7A 4FRZA 1VFVA 4PJNA 4A28A 1D0XA 2UYIA 3WPNA 3CJOA 2ZFKA 2X7EA 3PXNA 1G8XA 2XT3A 4PJLA 5LT1A 4E7SA 2UYMA 3KINA 2Y5WA 1Q0BA 3K3BA 4BXNA 3ZFCA 3B6VA 2NCDA 1VFWA 2XAEA 4A14A 2VVGA 4PFOA 4ETPA 4DBQA 1X88A 1F9VA 1D1BA 1RY6A 4PK4A 2Q2YA 3L9HA 1BR2A 1LKXA 3T0QA 2ZFMA 2IEHA 1GOJA 1V8KA 1FMVA 4PFPA 4A50A 3ZFDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I6I A;  1VFZ A;  1D1A A;  3COB A;  1MKJ A;  2FL6 A;  3DC4 A;  1MMG A;  5LT0 A;  2FME A;  3KAR A;  2X2R A;  1MMA A;  5LT2 A;  4A1Z A;  3HQD A;  4ZCA A;  1BG2 A;  1MMD A;  1F9W A;  4AP0 A;  4A51 A;  3U06 A;  1MNE A;  1D0Y A;  2VB6 A;  5GSZ A;  2WOG A;  4BBG A;  4E7Z A;  2FKY A;  1F9T A;  3L1C A;  3X2T A;  1II6 A;  4A5Y A;  2GRY A;  4ZHI A;  2FL2 A;  1BR4 A;  1BR1 A;  1FMW A;  2X7D A;  2Q2Z A;  1T5C A;  1VFX A;  3DCB A;  3LRE A;  4HNA K;  1N6M A;  2VAS A;  2X7C A;  1MMN A;  4PJJ A;  2X51 A;  2ZFI A;  3B6U A;  1SDM A;  1V8J A;  1I5S A;  2HEH A;  3GBJ A;  1D1C A;  2ZFJ A;  3NWN A;  4LNU K;  3K5E A;  1D0Z A;  4H1G A;  4DBR A;  1LVK A;  2ZFL A;  1YRS A;  2G1Q A;  2V26 A;  2KIN A;  1F9U A;  2Y65 A;  1VOM A;  4AS7 A;  3CNZ A;  3ZCW A;  2GM1 A;  4GKR A;  5HLE A;  3BFN A;  5LT3 A;  2OWM A;  3H4S A;  3WRD A;  4Y05 A;  2MYS A;  4UBF A;  4PJM A;  1KK7 A;  4BN2 A;  3KEN A;  4ANJ A;  5LT4 A;  2PG2 A;  4B7B A;  1CZ7 A;  4FRZ A;  1VFV A;  4PJN A;  4A28 A;  1D0X A;  2UYI A;  3WPN A;  3CJO A;  2ZFK A;  2X7E A;  3PXN A;  1G8X A;  2XT3 A;  4PJL A;  5LT1 A;  4E7S A;  2UYM A;  3KIN A;  2Y5W A;  1Q0B A;  3K3B A;  4BXN A;  3ZFC A;  3B6V A;  2NCD A;  1VFW A;  2XAE A;  4A14 A;  2VVG A;  4PFO A;  4ETP A;  4DBQ A;  1X88 A;  1F9V A;  1D1B A;  1RY6 A;  4PK4 A;  2Q2Y A;  3L9H A;  1BR2 A;  1LKX A;  3T0Q A;  2ZFM A;  2IEH A;  1GOJ A;  1V8K A;  1FMV A;  4PFP A;  4A50 A;  3ZFD A; 
#chains in the Genus database with same CATH topology
 4GKP A;  1I6I A;  4GKQ A;  1VFZ A;  1D1A A;  3COB A;  1MKJ A;  2FL6 A;  3DC4 A;  1MMG A;  5LT0 A;  2FME A;  3KAR A;  2X2R A;  1MMA A;  5LT2 A;  4A1Z A;  3HQD A;  4ZCA A;  1BG2 A;  1MMD A;  1F9W A;  4AP0 A;  4A51 A;  3U06 A;  1MNE A;  1D0Y A;  2VB6 A;  5GSZ A;  2WOG A;  4BBG A;  4E7Z A;  2FKY A;  1F9T A;  3L1C A;  3X2T A;  4ETP B;  1II6 A;  4A5Y A;  2GRY A;  4ZHI A;  2FL2 A;  1BR4 A;  1BR1 A;  1FMW A;  2X7D A;  2Q2Z A;  1T5C A;  1VFX A;  3DCB A;  3LRE A;  4HNA K;  1N6M A;  2VAS A;  2X7C A;  1MMN A;  4PJJ A;  2X51 A;  2ZFI A;  3B6U A;  1SDM A;  1V8J A;  1I5S A;  2HEH A;  3GBJ A;  1D1C A;  2ZFJ A;  3NWN A;  4LNU K;  3K5E A;  1D0Z A;  4H1G A;  4DBR A;  1LVK A;  2ZFL A;  1YRS A;  2G1Q A;  2V26 A;  2KIN A;  1F9U A;  2Y65 A;  1VOM A;  4AS7 A;  3CNZ A;  3ZCW A;  2GM1 A;  4GKR A;  5HLE A;  3BFN A;  5LT3 A;  2OWM A;  3H4S A;  3WRD A;  4Y05 A;  2MYS A;  4UBF A;  4PJM A;  1KK7 A;  4BN2 A;  3KEN A;  4ANJ A;  5LT4 A;  2PG2 A;  4B7B A;  1CZ7 A;  4FRZ A;  1VFV A;  4PJN A;  4A28 A;  1D0X A;  2UYI A;  3WPN A;  3CJO A;  2ZFK A;  2X7E A;  3PXN A;  1G8X A;  2XT3 A;  4PJL A;  5LT1 A;  4E7S A;  2UYM A;  3KIN A;  2Y5W A;  1Q0B A;  3K3B A;  4BXN A;  3ZFC A;  3B6V A;  2NCD A;  1VFW A;  2XAE A;  4A14 A;  2VVG A;  2O0A A;  4PFO A;  4ETP A;  4DBQ A;  1X88 A;  1F9V A;  1D1B A;  1RY6 A;  4PK4 A;  2Q2Y A;  3L9H A;  1BR2 A;  1LKX A;  3T0Q A;  2ZFM A;  2IEH A;  1GOJ A;  1V8K A;  1FMV A;  4PFP A;  4A50 A;  3ZFD A; 
#chains in the Genus database with same CATH homology
 1I6I A;  1VFZ A;  1D1A A;  3COB A;  1MKJ A;  2FL6 A;  3DC4 A;  1MMG A;  5LT0 A;  2FME A;  3KAR A;  2X2R A;  1MMA A;  5LT2 A;  4A1Z A;  3HQD A;  4ZCA A;  1BG2 A;  1MMD A;  1F9W A;  4AP0 A;  4A51 A;  3U06 A;  1MNE A;  1D0Y A;  2VB6 A;  5GSZ A;  2WOG A;  4BBG A;  4E7Z A;  2FKY A;  1F9T A;  3L1C A;  3X2T A;  1II6 A;  4A5Y A;  2GRY A;  4ZHI A;  2FL2 A;  1BR4 A;  1BR1 A;  1FMW A;  2X7D A;  2Q2Z A;  1T5C A;  1VFX A;  3DCB A;  3LRE A;  4HNA K;  1N6M A;  2VAS A;  2X7C A;  1MMN A;  4PJJ A;  2X51 A;  2ZFI A;  3B6U A;  1SDM A;  1V8J A;  1I5S A;  2HEH A;  3GBJ A;  1D1C A;  2ZFJ A;  3NWN A;  4LNU K;  3K5E A;  1D0Z A;  4H1G A;  4DBR A;  1LVK A;  2ZFL A;  1YRS A;  2G1Q A;  2V26 A;  2KIN A;  1F9U A;  2Y65 A;  1VOM A;  4AS7 A;  3CNZ A;  3ZCW A;  2GM1 A;  4GKR A;  5HLE A;  3BFN A;  5LT3 A;  2OWM A;  3H4S A;  3WRD A;  4Y05 A;  2MYS A;  4UBF A;  4PJM A;  1KK7 A;  4BN2 A;  3KEN A;  4ANJ A;  5LT4 A;  2PG2 A;  4B7B A;  1CZ7 A;  4FRZ A;  1VFV A;  4PJN A;  4A28 A;  1D0X A;  2UYI A;  3WPN A;  3CJO A;  2ZFK A;  2X7E A;  3PXN A;  1G8X A;  2XT3 A;  4PJL A;  5LT1 A;  4E7S A;  2UYM A;  3KIN A;  2Y5W A;  1Q0B A;  3K3B A;  4BXN A;  3ZFC A;  3B6V A;  2NCD A;  1VFW A;  2XAE A;  4A14 A;  2VVG A;  4PFO A;  4ETP A;  4DBQ A;  1X88 A;  1F9V A;  1D1B A;  1RY6 A;  4PK4 A;  2Q2Y A;  3L9H A;  1BR2 A;  1LKX A;  3T0Q A;  2ZFM A;  2IEH A;  1GOJ A;  1V8K A;  1FMV A;  4PFP A;  4A50 A;  3ZFD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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