5LT4A

Nucleotide-free kinesin-1 motor domain t92v mutant, p1 crystal form
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
321
structure length
313
Chain Sequence
LAESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKVHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural switch of nucleotide-free kinesin.
pubmed doi rcsb
molecule tags Motor protein
source organism Homo sapiens
molecule keywords Kinesin-1 heavy chain
total genus 97
structure length 313
sequence length 321
chains with identical sequence B, C, D, E, K
ec nomenclature
pdb deposition date 2016-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 5lt4A00
4PJLA 4DBRA 2X7CA 1SDMA 4A5YA 1VOMA 4UBFA 3U06A 2X7EA 5LT1A 2ZFLA 1MMAA 1GOJA 3CNZA 1D0ZA 2VVGA 2XT3A 1D1AA 4FRZA 3ZFCA 4GKRA 3KINA 1YRSA 4H1GA 4A51A 4E7ZA 1VFVA 2V26A 1V8JA 1BR4A 4PJJA 3WRDA 1FMVA 1D0YA 2GRYA 5LT0A 2ZFJA 2X2RA 2FMEA 2X51A 4LNUK 3DC4A 3CJOA 1KK7A 1I5SA 1VFWA 4BN2A 1VFXA 2NCDA 4ANJA 2PG2A 1BR1A 2FKYA 1MNEA 1MKJA 2FL6A 2Q2YA 4BBGA 2XAEA 1G8XA 2FL2A 2ZFKA 1Q0BA 4HNAK 1F9TA 2Y5WA 5LT2A 3X2TA 3BFNA 1CZ7A 3DCBA 3ZFDA 2UYIA 3L9HA 4PJMA 2ZFIA 3ZCWA 2Q2ZA 1MMGA 3B6VA 3PXNA 1F9WA 1VFZA 2KINA 2IEHA 2ZFMA 3T0QA 4PK4A 4ETPA 4PJNA 3NWNA 2GM1A 5GSZA 1LKXA 1RY6A 1II6A 1X88A 1D1CA 1BG2A 1F9VA 2HEHA 3B6UA 4E7SA 4A28A 1MMDA 5LT4A 2WOGA 4AP0A 4B7BA 1FMWA 4AS7A 4ZHIA 1D1BA 2G1QA 2OWMA 3HQDA 1T5CA 3L1CA 1I6IA 4PFPA 1LVKA 2UYMA 4A14A 2X7DA 2VASA 4ZCAA 3H4SA 4A50A 4A1ZA 3COBA 1V8KA 3K5EA 1N6MA 3KENA 1F9UA 3WPNA 5LT3A 3GBJA 1BR2A 2VB6A 3LREA 3K3BA 1D0XA 3KARA 1MMNA 2Y65A 5HLEA 4DBQA 4BXNA 2MYSA 4Y05A 4PFOA
chains in the Genus database with same CATH superfamily
4PJLA 4DBRA 2X7CA 1SDMA 4A5YA 1VOMA 4UBFA 3U06A 2X7EA 5LT1A 2ZFLA 1MMAA 1GOJA 3CNZA 1D0ZA 2VVGA 2XT3A 1D1AA 4FRZA 3ZFCA 4GKRA 3KINA 1YRSA 4H1GA 4A51A 4E7ZA 1VFVA 4GKQA 2V26A 1V8JA 1BR4A 4PJJA 3WRDA 1FMVA 1D0YA 2GRYA 5LT0A 2ZFJA 2X2RA 2FMEA 2X51A 4LNUK 3DC4A 3CJOA 1KK7A 1I5SA 1VFWA 4BN2A 1VFXA 2NCDA 4ANJA 2PG2A 1BR1A 2FKYA 1MNEA 1MKJA 2FL6A 2Q2YA 4BBGA 2XAEA 1G8XA 2FL2A 2ZFKA 1Q0BA 4HNAK 4ETPB 1F9TA 2Y5WA 5LT2A 3X2TA 3BFNA 1CZ7A 4GKPA 3DCBA 3ZFDA 2UYIA 3L9HA 4PJMA 2ZFIA 3ZCWA 2Q2ZA 1MMGA 3B6VA 3PXNA 1F9WA 1VFZA 2KINA 2IEHA 2ZFMA 3T0QA 4PK4A 4ETPA 4PJNA 3NWNA 2GM1A 5GSZA 1LKXA 1RY6A 1II6A 1X88A 1D1CA 1BG2A 1F9VA 2HEHA 3B6UA 4E7SA 4A28A 1MMDA 5LT4A 2WOGA 4AP0A 4B7BA 1FMWA 4AS7A 4ZHIA 1D1BA 2G1QA 2OWMA 3HQDA 1T5CA 3L1CA 1I6IA 4PFPA 1LVKA 2UYMA 4A14A 2X7DA 2VASA 4ZCAA 3H4SA 4A50A 4A1ZA 3COBA 1V8KA 3K5EA 1N6MA 3KENA 1F9UA 3WPNA 5LT3A 3GBJA 1BR2A 2VB6A 3LREA 3K3BA 1D0XA 3KARA 1MMNA 2Y65A 5HLEA 4DBQA 4BXNA 2MYSA 2O0AA 4Y05A 4PFOA
chains in the Genus database with same CATH topology
4PJLA 4DBRA 2X7CA 1SDMA 4A5YA 1VOMA 4UBFA 3U06A 2X7EA 5LT1A 2ZFLA 1MMAA 1GOJA 3CNZA 1D0ZA 2VVGA 2XT3A 1D1AA 4FRZA 3ZFCA 4GKRA 3KINA 1YRSA 4H1GA 4A51A 4E7ZA 1VFVA 2V26A 1V8JA 1BR4A 4PJJA 3WRDA 1FMVA 1D0YA 2GRYA 5LT0A 2ZFJA 2X2RA 2FMEA 2X51A 4LNUK 3DC4A 3CJOA 1KK7A 1I5SA 1VFWA 4BN2A 1VFXA 2NCDA 4ANJA 2PG2A 1BR1A 2FKYA 1MNEA 1MKJA 2FL6A 2Q2YA 4BBGA 2XAEA 1G8XA 2FL2A 2ZFKA 1Q0BA 4HNAK 1F9TA 2Y5WA 5LT2A 3X2TA 3BFNA 1CZ7A 3DCBA 3ZFDA 2UYIA 3L9HA 4PJMA 2ZFIA 3ZCWA 2Q2ZA 1MMGA 3B6VA 3PXNA 1F9WA 1VFZA 2KINA 2IEHA 2ZFMA 3T0QA 4PK4A 4ETPA 4PJNA 3NWNA 2GM1A 5GSZA 1LKXA 1RY6A 1II6A 1X88A 1D1CA 1BG2A 1F9VA 2HEHA 3B6UA 4E7SA 4A28A 1MMDA 5LT4A 2WOGA 4AP0A 4B7BA 1FMWA 4AS7A 4ZHIA 1D1BA 2G1QA 2OWMA 3HQDA 1T5CA 3L1CA 1I6IA 4PFPA 1LVKA 2UYMA 4A14A 2X7DA 2VASA 4ZCAA 3H4SA 4A50A 4A1ZA 3COBA 1V8KA 3K5EA 1N6MA 3KENA 1F9UA 3WPNA 5LT3A 3GBJA 1BR2A 2VB6A 3LREA 3K3BA 1D0XA 3KARA 1MMNA 2Y65A 5HLEA 4DBQA 4BXNA 2MYSA 4Y05A 4PFOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PJL A;  4DBR A;  2X7C A;  1SDM A;  4A5Y A;  1VOM A;  4UBF A;  3U06 A;  2X7E A;  5LT1 A;  2ZFL A;  1MMA A;  1GOJ A;  3CNZ A;  1D0Z A;  2VVG A;  2XT3 A;  1D1A A;  4FRZ A;  3ZFC A;  4GKR A;  3KIN A;  1YRS A;  4H1G A;  4A51 A;  4E7Z A;  1VFV A;  2V26 A;  1V8J A;  1BR4 A;  4PJJ A;  3WRD A;  1FMV A;  1D0Y A;  2GRY A;  5LT0 A;  2ZFJ A;  2X2R A;  2FME A;  2X51 A;  4LNU K;  3DC4 A;  3CJO A;  1KK7 A;  1I5S A;  1VFW A;  4BN2 A;  1VFX A;  2NCD A;  4ANJ A;  2PG2 A;  1BR1 A;  2FKY A;  1MNE A;  1MKJ A;  2FL6 A;  2Q2Y A;  4BBG A;  2XAE A;  1G8X A;  2FL2 A;  2ZFK A;  1Q0B A;  4HNA K;  1F9T A;  2Y5W A;  5LT2 A;  3X2T A;  3BFN A;  1CZ7 A;  3DCB A;  3ZFD A;  2UYI A;  3L9H A;  4PJM A;  2ZFI A;  3ZCW A;  2Q2Z A;  1MMG A;  3B6V A;  3PXN A;  1F9W A;  1VFZ A;  2KIN A;  2IEH A;  2ZFM A;  3T0Q A;  4PK4 A;  4ETP A;  4PJN A;  3NWN A;  2GM1 A;  5GSZ A;  1LKX A;  1RY6 A;  1II6 A;  1X88 A;  1D1C A;  1BG2 A;  1F9V A;  2HEH A;  3B6U A;  4E7S A;  4A28 A;  1MMD A;  5LT4 A;  2WOG A;  4AP0 A;  4B7B A;  1FMW A;  4AS7 A;  4ZHI A;  1D1B A;  2G1Q A;  2OWM A;  3HQD A;  1T5C A;  3L1C A;  1I6I A;  4PFP A;  1LVK A;  2UYM A;  4A14 A;  2X7D A;  2VAS A;  4ZCA A;  3H4S A;  4A50 A;  4A1Z A;  3COB A;  1V8K A;  3K5E A;  1N6M A;  3KEN A;  1F9U A;  3WPN A;  5LT3 A;  3GBJ A;  1BR2 A;  2VB6 A;  3LRE A;  3K3B A;  1D0X A;  3KAR A;  1MMN A;  2Y65 A;  5HLE A;  4DBQ A;  4BXN A;  2MYS A;  4Y05 A;  4PFO A; 
#chains in the Genus database with same CATH topology
 4PJL A;  4DBR A;  2X7C A;  1SDM A;  4A5Y A;  1VOM A;  4UBF A;  3U06 A;  2X7E A;  5LT1 A;  2ZFL A;  1MMA A;  1GOJ A;  3CNZ A;  1D0Z A;  2VVG A;  2XT3 A;  1D1A A;  4FRZ A;  3ZFC A;  4GKR A;  3KIN A;  1YRS A;  4H1G A;  4A51 A;  4E7Z A;  1VFV A;  4GKQ A;  2V26 A;  1V8J A;  1BR4 A;  4PJJ A;  3WRD A;  1FMV A;  1D0Y A;  2GRY A;  5LT0 A;  2ZFJ A;  2X2R A;  2FME A;  2X51 A;  4LNU K;  3DC4 A;  3CJO A;  1KK7 A;  1I5S A;  1VFW A;  4BN2 A;  1VFX A;  2NCD A;  4ANJ A;  2PG2 A;  1BR1 A;  2FKY A;  1MNE A;  1MKJ A;  2FL6 A;  2Q2Y A;  4BBG A;  2XAE A;  1G8X A;  2FL2 A;  2ZFK A;  1Q0B A;  4HNA K;  4ETP B;  1F9T A;  2Y5W A;  5LT2 A;  3X2T A;  3BFN A;  1CZ7 A;  4GKP A;  3DCB A;  3ZFD A;  2UYI A;  3L9H A;  4PJM A;  2ZFI A;  3ZCW A;  2Q2Z A;  1MMG A;  3B6V A;  3PXN A;  1F9W A;  1VFZ A;  2KIN A;  2IEH A;  2ZFM A;  3T0Q A;  4PK4 A;  4ETP A;  4PJN A;  3NWN A;  2GM1 A;  5GSZ A;  1LKX A;  1RY6 A;  1II6 A;  1X88 A;  1D1C A;  1BG2 A;  1F9V A;  2HEH A;  3B6U A;  4E7S A;  4A28 A;  1MMD A;  5LT4 A;  2WOG A;  4AP0 A;  4B7B A;  1FMW A;  4AS7 A;  4ZHI A;  1D1B A;  2G1Q A;  2OWM A;  3HQD A;  1T5C A;  3L1C A;  1I6I A;  4PFP A;  1LVK A;  2UYM A;  4A14 A;  2X7D A;  2VAS A;  4ZCA A;  3H4S A;  4A50 A;  4A1Z A;  3COB A;  1V8K A;  3K5E A;  1N6M A;  3KEN A;  1F9U A;  3WPN A;  5LT3 A;  3GBJ A;  1BR2 A;  2VB6 A;  3LRE A;  3K3B A;  1D0X A;  3KAR A;  1MMN A;  2Y65 A;  5HLE A;  4DBQ A;  4BXN A;  2MYS A;  2O0A A;  4Y05 A;  4PFO A; 
#chains in the Genus database with same CATH homology
 4PJL A;  4DBR A;  2X7C A;  1SDM A;  4A5Y A;  1VOM A;  4UBF A;  3U06 A;  2X7E A;  5LT1 A;  2ZFL A;  1MMA A;  1GOJ A;  3CNZ A;  1D0Z A;  2VVG A;  2XT3 A;  1D1A A;  4FRZ A;  3ZFC A;  4GKR A;  3KIN A;  1YRS A;  4H1G A;  4A51 A;  4E7Z A;  1VFV A;  2V26 A;  1V8J A;  1BR4 A;  4PJJ A;  3WRD A;  1FMV A;  1D0Y A;  2GRY A;  5LT0 A;  2ZFJ A;  2X2R A;  2FME A;  2X51 A;  4LNU K;  3DC4 A;  3CJO A;  1KK7 A;  1I5S A;  1VFW A;  4BN2 A;  1VFX A;  2NCD A;  4ANJ A;  2PG2 A;  1BR1 A;  2FKY A;  1MNE A;  1MKJ A;  2FL6 A;  2Q2Y A;  4BBG A;  2XAE A;  1G8X A;  2FL2 A;  2ZFK A;  1Q0B A;  4HNA K;  1F9T A;  2Y5W A;  5LT2 A;  3X2T A;  3BFN A;  1CZ7 A;  3DCB A;  3ZFD A;  2UYI A;  3L9H A;  4PJM A;  2ZFI A;  3ZCW A;  2Q2Z A;  1MMG A;  3B6V A;  3PXN A;  1F9W A;  1VFZ A;  2KIN A;  2IEH A;  2ZFM A;  3T0Q A;  4PK4 A;  4ETP A;  4PJN A;  3NWN A;  2GM1 A;  5GSZ A;  1LKX A;  1RY6 A;  1II6 A;  1X88 A;  1D1C A;  1BG2 A;  1F9V A;  2HEH A;  3B6U A;  4E7S A;  4A28 A;  1MMD A;  5LT4 A;  2WOG A;  4AP0 A;  4B7B A;  1FMW A;  4AS7 A;  4ZHI A;  1D1B A;  2G1Q A;  2OWM A;  3HQD A;  1T5C A;  3L1C A;  1I6I A;  4PFP A;  1LVK A;  2UYM A;  4A14 A;  2X7D A;  2VAS A;  4ZCA A;  3H4S A;  4A50 A;  4A1Z A;  3COB A;  1V8K A;  3K5E A;  1N6M A;  3KEN A;  1F9U A;  3WPN A;  5LT3 A;  3GBJ A;  1BR2 A;  2VB6 A;  3LRE A;  3K3B A;  1D0X A;  3KAR A;  1MMN A;  2Y65 A;  5HLE A;  4DBQ A;  4BXN A;  2MYS A;  4Y05 A;  4PFO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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