5LT4A

Nucleotide-free kinesin-1 motor domain t92v mutant, p1 crystal form
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
321
structure length
313
Chain Sequence
b'LAESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKVHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Kinesin-1 heavy chain
publication title The structural switch of nucleotide-free kinesin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Motor protein
total genus 97
structure length 313
sequence length 321
chains with identical sequence B, C, D, E, K
ec nomenclature
pdb deposition date 2016-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 5lt4A00
4Y05A 1D0YA 2PG2A 1VFWA 2V26A 3CJOA 4PJMA 1MMGA 3COBA 3L1CA 3B6VA 5GSZA 2X7EA 2Y5WA 5LT1A 1D0ZA 1I6IA 3NWNA 1G8XA 4A51A 1LKXA 4DBRA 1MMDA 2ZFLA 1VFXA 5LT3A 4BN2A 2VB6A 4PK4A 2Y65A 4PFPA 3KARA 1V8JA 2IEHA 1BR4A 4AS7A 2X51A 1D1AA 2X7CA 1VFZA 4FRZA 4LNUK 2G1QA 2GRYA 1FMVA 2NCDA 3B6UA 4ZHIA 1YRSA 1FMWA 1F9WA 4HNAK 3WPNA 2Q2YA 4GKRA 2ZFIA 2UYIA 1MMAA 3HQDA 3KINA 3K5EA 5LT2A 3L9HA 1VOMA 1MMNA 1F9TA 4PJNA 1GOJA 1V8KA 4BXNA 1I5SA 5LT0A 4ZCAA 3WRDA 1Q0BA 4PFOA 4UBFA 4E7SA 4E7ZA 3PXNA 1T5CA 4H1GA 2XAEA 5HLEA 1BR2A 2WOGA 3X2TA 2ZFKA 3K3BA 3ZFCA 3H4SA 4BBGA 1X88A 5LT4A 2HEHA 3ZFDA 1F9UA 3DCBA 2FKYA 1LVKA 2FL2A 4A50A 1MKJA 3ZCWA 4A5YA 1CZ7A 1KK7A 2FMEA 2X2RA 2UYMA 4B7BA 4AP0A 1D0XA 1BG2A 2VVGA 2OWMA 2ZFJA 3LREA 2Q2ZA 3DC4A 1F9VA 4ETPA 3KENA 1VFVA 4PJJA 1N6MA 3U06A 1D1BA 3CNZA 4A28A 1D1CA 4ANJA 4A14A 1MNEA 4PJLA 2KINA 2MYSA 2XT3A 1RY6A 2X7DA 3GBJA 2VASA 4A1ZA 2FL6A 1SDMA 1BR1A 2GM1A 2ZFMA 1II6A 3T0QA 3BFNA 4DBQA
chains in the Genus database with same CATH superfamily
4Y05A 1D0YA 2PG2A 1VFWA 2V26A 3CJOA 4PJMA 1MMGA 3COBA 3L1CA 3B6VA 5GSZA 2X7EA 2Y5WA 5LT1A 1D0ZA 1I6IA 3NWNA 1G8XA 4A51A 1LKXA 4DBRA 1MMDA 2ZFLA 1VFXA 5LT3A 4BN2A 2VB6A 4PK4A 2Y65A 4PFPA 3KARA 1V8JA 2IEHA 1BR4A 4AS7A 2X51A 1D1AA 2X7CA 1VFZA 4FRZA 4LNUK 2G1QA 2GRYA 1FMVA 2NCDA 4GKPA 3B6UA 4ZHIA 1YRSA 1FMWA 1F9WA 4HNAK 3WPNA 2Q2YA 4GKRA 4ETPB 2ZFIA 2UYIA 1MMAA 3HQDA 3KINA 3K5EA 5LT2A 3L9HA 1VOMA 1MMNA 1F9TA 4PJNA 1GOJA 1V8KA 4BXNA 1I5SA 5LT0A 4ZCAA 3WRDA 1Q0BA 4PFOA 4UBFA 4E7SA 4E7ZA 3PXNA 1T5CA 4H1GA 2XAEA 5HLEA 1BR2A 2WOGA 3X2TA 2ZFKA 3K3BA 3ZFCA 3H4SA 4BBGA 1X88A 5LT4A 2HEHA 3ZFDA 1F9UA 2O0AA 3DCBA 2FKYA 1LVKA 2FL2A 4A50A 1MKJA 3ZCWA 4A5YA 1CZ7A 1KK7A 2FMEA 2X2RA 2UYMA 4B7BA 4AP0A 1D0XA 1BG2A 2VVGA 2OWMA 2ZFJA 3LREA 2Q2ZA 3DC4A 1F9VA 4ETPA 3KENA 1VFVA 4PJJA 1N6MA 3U06A 1D1BA 3CNZA 4A28A 1D1CA 4ANJA 4A14A 1MNEA 4PJLA 2KINA 4GKQA 2MYSA 2XT3A 1RY6A 2X7DA 3GBJA 2VASA 4A1ZA 2FL6A 1SDMA 1BR1A 2GM1A 2ZFMA 1II6A 3T0QA 3BFNA 4DBQA
chains in the Genus database with same CATH topology
4Y05A 1D0YA 2PG2A 1VFWA 2V26A 3CJOA 4PJMA 1MMGA 3COBA 3L1CA 3B6VA 5GSZA 2X7EA 2Y5WA 5LT1A 1D0ZA 1I6IA 3NWNA 1G8XA 4A51A 1LKXA 4DBRA 1MMDA 2ZFLA 1VFXA 5LT3A 4BN2A 2VB6A 4PK4A 2Y65A 4PFPA 3KARA 1V8JA 2IEHA 1BR4A 4AS7A 2X51A 1D1AA 2X7CA 1VFZA 4FRZA 4LNUK 2G1QA 2GRYA 1FMVA 2NCDA 3B6UA 4ZHIA 1YRSA 1FMWA 1F9WA 4HNAK 3WPNA 2Q2YA 4GKRA 2ZFIA 2UYIA 1MMAA 3HQDA 3KINA 3K5EA 5LT2A 3L9HA 1VOMA 1MMNA 1F9TA 4PJNA 1GOJA 1V8KA 4BXNA 1I5SA 5LT0A 4ZCAA 3WRDA 1Q0BA 4PFOA 4UBFA 4E7SA 4E7ZA 3PXNA 1T5CA 4H1GA 2XAEA 5HLEA 1BR2A 2WOGA 3X2TA 2ZFKA 3K3BA 3ZFCA 3H4SA 4BBGA 1X88A 5LT4A 2HEHA 3ZFDA 1F9UA 3DCBA 2FKYA 1LVKA 2FL2A 4A50A 1MKJA 3ZCWA 4A5YA 1CZ7A 1KK7A 2FMEA 2X2RA 2UYMA 4B7BA 4AP0A 1D0XA 1BG2A 2VVGA 2OWMA 2ZFJA 3LREA 2Q2ZA 3DC4A 1F9VA 4ETPA 3KENA 1VFVA 4PJJA 1N6MA 3U06A 1D1BA 3CNZA 4A28A 1D1CA 4ANJA 4A14A 1MNEA 4PJLA 2KINA 2MYSA 2XT3A 1RY6A 2X7DA 3GBJA 2VASA 4A1ZA 2FL6A 1SDMA 1BR1A 2GM1A 2ZFMA 1II6A 3T0QA 3BFNA 4DBQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y05 A;  1D0Y A;  2PG2 A;  1VFW A;  2V26 A;  3CJO A;  4PJM A;  1MMG A;  3COB A;  3L1C A;  3B6V A;  5GSZ A;  2X7E A;  2Y5W A;  5LT1 A;  1D0Z A;  1I6I A;  3NWN A;  1G8X A;  4A51 A;  1LKX A;  4DBR A;  1MMD A;  2ZFL A;  1VFX A;  5LT3 A;  4BN2 A;  2VB6 A;  4PK4 A;  2Y65 A;  4PFP A;  3KAR A;  1V8J A;  2IEH A;  1BR4 A;  4AS7 A;  2X51 A;  1D1A A;  2X7C A;  1VFZ A;  4FRZ A;  4LNU K;  2G1Q A;  2GRY A;  1FMV A;  2NCD A;  3B6U A;  4ZHI A;  1YRS A;  1FMW A;  1F9W A;  4HNA K;  3WPN A;  2Q2Y A;  4GKR A;  2ZFI A;  2UYI A;  1MMA A;  3HQD A;  3KIN A;  3K5E A;  5LT2 A;  3L9H A;  1VOM A;  1MMN A;  1F9T A;  4PJN A;  1GOJ A;  1V8K A;  4BXN A;  1I5S A;  5LT0 A;  4ZCA A;  3WRD A;  1Q0B A;  4PFO A;  4UBF A;  4E7S A;  4E7Z A;  3PXN A;  1T5C A;  4H1G A;  2XAE A;  5HLE A;  1BR2 A;  2WOG A;  3X2T A;  2ZFK A;  3K3B A;  3ZFC A;  3H4S A;  4BBG A;  1X88 A;  5LT4 A;  2HEH A;  3ZFD A;  1F9U A;  3DCB A;  2FKY A;  1LVK A;  2FL2 A;  4A50 A;  1MKJ A;  3ZCW A;  4A5Y A;  1CZ7 A;  1KK7 A;  2FME A;  2X2R A;  2UYM A;  4B7B A;  4AP0 A;  1D0X A;  1BG2 A;  2VVG A;  2OWM A;  2ZFJ A;  3LRE A;  2Q2Z A;  3DC4 A;  1F9V A;  4ETP A;  3KEN A;  1VFV A;  4PJJ A;  1N6M A;  3U06 A;  1D1B A;  3CNZ A;  4A28 A;  1D1C A;  4ANJ A;  4A14 A;  1MNE A;  4PJL A;  2KIN A;  2MYS A;  2XT3 A;  1RY6 A;  2X7D A;  3GBJ A;  2VAS A;  4A1Z A;  2FL6 A;  1SDM A;  1BR1 A;  2GM1 A;  2ZFM A;  1II6 A;  3T0Q A;  3BFN A;  4DBQ A; 
#chains in the Genus database with same CATH topology
 4Y05 A;  1D0Y A;  2PG2 A;  1VFW A;  2V26 A;  3CJO A;  4PJM A;  1MMG A;  3COB A;  3L1C A;  3B6V A;  5GSZ A;  2X7E A;  2Y5W A;  5LT1 A;  1D0Z A;  1I6I A;  3NWN A;  1G8X A;  4A51 A;  1LKX A;  4DBR A;  1MMD A;  2ZFL A;  1VFX A;  5LT3 A;  4BN2 A;  2VB6 A;  4PK4 A;  2Y65 A;  4PFP A;  3KAR A;  1V8J A;  2IEH A;  1BR4 A;  4AS7 A;  2X51 A;  1D1A A;  2X7C A;  1VFZ A;  4FRZ A;  4LNU K;  2G1Q A;  2GRY A;  1FMV A;  2NCD A;  4GKP A;  3B6U A;  4ZHI A;  1YRS A;  1FMW A;  1F9W A;  4HNA K;  3WPN A;  2Q2Y A;  4GKR A;  4ETP B;  2ZFI A;  2UYI A;  1MMA A;  3HQD A;  3KIN A;  3K5E A;  5LT2 A;  3L9H A;  1VOM A;  1MMN A;  1F9T A;  4PJN A;  1GOJ A;  1V8K A;  4BXN A;  1I5S A;  5LT0 A;  4ZCA A;  3WRD A;  1Q0B A;  4PFO A;  4UBF A;  4E7S A;  4E7Z A;  3PXN A;  1T5C A;  4H1G A;  2XAE A;  5HLE A;  1BR2 A;  2WOG A;  3X2T A;  2ZFK A;  3K3B A;  3ZFC A;  3H4S A;  4BBG A;  1X88 A;  5LT4 A;  2HEH A;  3ZFD A;  1F9U A;  2O0A A;  3DCB A;  2FKY A;  1LVK A;  2FL2 A;  4A50 A;  1MKJ A;  3ZCW A;  4A5Y A;  1CZ7 A;  1KK7 A;  2FME A;  2X2R A;  2UYM A;  4B7B A;  4AP0 A;  1D0X A;  1BG2 A;  2VVG A;  2OWM A;  2ZFJ A;  3LRE A;  2Q2Z A;  3DC4 A;  1F9V A;  4ETP A;  3KEN A;  1VFV A;  4PJJ A;  1N6M A;  3U06 A;  1D1B A;  3CNZ A;  4A28 A;  1D1C A;  4ANJ A;  4A14 A;  1MNE A;  4PJL A;  2KIN A;  4GKQ A;  2MYS A;  2XT3 A;  1RY6 A;  2X7D A;  3GBJ A;  2VAS A;  4A1Z A;  2FL6 A;  1SDM A;  1BR1 A;  2GM1 A;  2ZFM A;  1II6 A;  3T0Q A;  3BFN A;  4DBQ A; 
#chains in the Genus database with same CATH homology
 4Y05 A;  1D0Y A;  2PG2 A;  1VFW A;  2V26 A;  3CJO A;  4PJM A;  1MMG A;  3COB A;  3L1C A;  3B6V A;  5GSZ A;  2X7E A;  2Y5W A;  5LT1 A;  1D0Z A;  1I6I A;  3NWN A;  1G8X A;  4A51 A;  1LKX A;  4DBR A;  1MMD A;  2ZFL A;  1VFX A;  5LT3 A;  4BN2 A;  2VB6 A;  4PK4 A;  2Y65 A;  4PFP A;  3KAR A;  1V8J A;  2IEH A;  1BR4 A;  4AS7 A;  2X51 A;  1D1A A;  2X7C A;  1VFZ A;  4FRZ A;  4LNU K;  2G1Q A;  2GRY A;  1FMV A;  2NCD A;  3B6U A;  4ZHI A;  1YRS A;  1FMW A;  1F9W A;  4HNA K;  3WPN A;  2Q2Y A;  4GKR A;  2ZFI A;  2UYI A;  1MMA A;  3HQD A;  3KIN A;  3K5E A;  5LT2 A;  3L9H A;  1VOM A;  1MMN A;  1F9T A;  4PJN A;  1GOJ A;  1V8K A;  4BXN A;  1I5S A;  5LT0 A;  4ZCA A;  3WRD A;  1Q0B A;  4PFO A;  4UBF A;  4E7S A;  4E7Z A;  3PXN A;  1T5C A;  4H1G A;  2XAE A;  5HLE A;  1BR2 A;  2WOG A;  3X2T A;  2ZFK A;  3K3B A;  3ZFC A;  3H4S A;  4BBG A;  1X88 A;  5LT4 A;  2HEH A;  3ZFD A;  1F9U A;  3DCB A;  2FKY A;  1LVK A;  2FL2 A;  4A50 A;  1MKJ A;  3ZCW A;  4A5Y A;  1CZ7 A;  1KK7 A;  2FME A;  2X2R A;  2UYM A;  4B7B A;  4AP0 A;  1D0X A;  1BG2 A;  2VVG A;  2OWM A;  2ZFJ A;  3LRE A;  2Q2Z A;  3DC4 A;  1F9V A;  4ETP A;  3KEN A;  1VFV A;  4PJJ A;  1N6M A;  3U06 A;  1D1B A;  3CNZ A;  4A28 A;  1D1C A;  4ANJ A;  4A14 A;  1MNE A;  4PJL A;  2KIN A;  2MYS A;  2XT3 A;  1RY6 A;  2X7D A;  3GBJ A;  2VAS A;  4A1Z A;  2FL6 A;  1SDM A;  1BR1 A;  2GM1 A;  2ZFM A;  1II6 A;  3T0Q A;  3BFN A;  4DBQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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