5LT4A

Nucleotide-free kinesin-1 motor domain t92v mutant, p1 crystal form
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
321
structure length
313
Chain Sequence
LAESNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKVHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Kinesin-1 heavy chain
publication title The structural switch of nucleotide-free kinesin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Motor protein
total genus 97
structure length 313
sequence length 321
chains with identical sequence B, C, D, E, K
ec nomenclature
pdb deposition date 2016-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 5lt4A00
1LVKA 1CZ7A 3B6UA 1N6MA 4PJJA 4PJMA 2ZFIA 3WRDA 4ANJA 3T0QA 3U06A 1VFXA 2FKYA 3KARA 1LKXA 3DC4A 4A51A 1Q0BA 2G1QA 2Y65A 4HNAK 2OWMA 3KINA 4AP0A 2GRYA 1YRSA 5HLEA 1X88A 2UYIA 1F9WA 4DBQA 1BR1A 4ETPA 2WOGA 2X2RA 4E7ZA 1D0XA 3K5EA 4PFPA 4ZHIA 5LT0A 1MMNA 1MMGA 5GSZA 5LT2A 1D0ZA 2XAEA 3L1CA 1D1CA 2ZFJA 2X7CA 2V26A 2X7EA 1SDMA 1MMAA 1MMDA 4AS7A 4BBGA 4E7SA 1F9VA 4PJLA 2NCDA 2X51A 3B6VA 4A28A 2ZFKA 1VFWA 3KENA 4PK4A 1FMVA 4ZCAA 2ZFLA 1V8KA 1MKJA 3NWNA 3WPNA 2VB6A 2Y5WA 3DCBA 1VFZA 4A50A 4B7BA 1T5CA 3COBA 3PXNA 2FL2A 2VVGA 4UBFA 1F9TA 2VASA 1BR4A 2Q2ZA 1I5SA 2Q2YA 1GOJA 1RY6A 2PG2A 1II6A 5LT4A 3BFNA 2FL6A 1FMWA 1I6IA 2IEHA 1VFVA 4PFOA 3ZFDA 3CNZA 1MNEA 4Y05A 1BR2A 4DBRA 1KK7A 3GBJA 2UYMA 2MYSA 4LNUK 5LT1A 2KINA 2X7DA 4A14A 2XT3A 3L9HA 3H4SA 4A1ZA 1D1AA 1BG2A 3K3BA 4A5YA 4PJNA 4GKRA 3ZFCA 1VOMA 2ZFMA 4FRZA 1D0YA 3CJOA 3LREA 2GM1A 3X2TA 4H1GA 1V8JA 5LT3A 1G8XA 4BXNA 3HQDA 4BN2A 3ZCWA 2HEHA 1F9UA 2FMEA 1D1BA
chains in the Genus database with same CATH superfamily
1LVKA 1CZ7A 3B6UA 1N6MA 4PJJA 4PJMA 2ZFIA 3WRDA 4ANJA 3T0QA 3U06A 1VFXA 2FKYA 3KARA 1LKXA 3DC4A 4A51A 1Q0BA 2G1QA 2Y65A 4HNAK 2OWMA 3KINA 4AP0A 2GRYA 1YRSA 5HLEA 1X88A 2UYIA 1F9WA 4DBQA 1BR1A 4ETPA 2WOGA 2X2RA 4E7ZA 1D0XA 3K5EA 4PFPA 4ZHIA 5LT0A 1MMNA 1MMGA 5GSZA 5LT2A 1D0ZA 2XAEA 3L1CA 1D1CA 2ZFJA 2X7CA 2V26A 2X7EA 1SDMA 1MMAA 1MMDA 4AS7A 4BBGA 4E7SA 1F9VA 4PJLA 2NCDA 2X51A 3B6VA 4A28A 2ZFKA 1VFWA 3KENA 4PK4A 1FMVA 4ZCAA 2ZFLA 1V8KA 1MKJA 3NWNA 3WPNA 2VB6A 2Y5WA 3DCBA 1VFZA 4A50A 4B7BA 1T5CA 3COBA 3PXNA 2FL2A 2VVGA 4GKPA 4UBFA 1F9TA 2VASA 1BR4A 2Q2ZA 1I5SA 2Q2YA 1GOJA 1RY6A 2PG2A 1II6A 5LT4A 3BFNA 2FL6A 1FMWA 1I6IA 2IEHA 1VFVA 2O0AA 4PFOA 3ZFDA 3CNZA 1MNEA 4Y05A 1BR2A 4DBRA 1KK7A 3GBJA 2UYMA 2MYSA 4LNUK 5LT1A 4GKQA 2KINA 2X7DA 4ETPB 4A14A 2XT3A 3L9HA 3H4SA 4A1ZA 1D1AA 1BG2A 3K3BA 4A5YA 4PJNA 4GKRA 3ZFCA 1VOMA 2ZFMA 4FRZA 1D0YA 3CJOA 3LREA 2GM1A 3X2TA 4H1GA 1V8JA 5LT3A 1G8XA 4BXNA 3HQDA 4BN2A 3ZCWA 2HEHA 1F9UA 2FMEA 1D1BA
chains in the Genus database with same CATH topology
1LVKA 1CZ7A 3B6UA 1N6MA 4PJJA 4PJMA 2ZFIA 3WRDA 4ANJA 3T0QA 3U06A 1VFXA 2FKYA 3KARA 1LKXA 3DC4A 4A51A 1Q0BA 2G1QA 2Y65A 4HNAK 2OWMA 3KINA 4AP0A 2GRYA 1YRSA 5HLEA 1X88A 2UYIA 1F9WA 4DBQA 1BR1A 4ETPA 2WOGA 2X2RA 4E7ZA 1D0XA 3K5EA 4PFPA 4ZHIA 5LT0A 1MMNA 1MMGA 5GSZA 5LT2A 1D0ZA 2XAEA 3L1CA 1D1CA 2ZFJA 2X7CA 2V26A 2X7EA 1SDMA 1MMAA 1MMDA 4AS7A 4BBGA 4E7SA 1F9VA 4PJLA 2NCDA 2X51A 3B6VA 4A28A 2ZFKA 1VFWA 3KENA 4PK4A 1FMVA 4ZCAA 2ZFLA 1V8KA 1MKJA 3NWNA 3WPNA 2VB6A 2Y5WA 3DCBA 1VFZA 4A50A 4B7BA 1T5CA 3COBA 3PXNA 2FL2A 2VVGA 4UBFA 1F9TA 2VASA 1BR4A 2Q2ZA 1I5SA 2Q2YA 1GOJA 1RY6A 2PG2A 1II6A 5LT4A 3BFNA 2FL6A 1FMWA 1I6IA 2IEHA 1VFVA 4PFOA 3ZFDA 3CNZA 1MNEA 4Y05A 1BR2A 4DBRA 1KK7A 3GBJA 2UYMA 2MYSA 4LNUK 5LT1A 2KINA 2X7DA 4A14A 2XT3A 3L9HA 3H4SA 4A1ZA 1D1AA 1BG2A 3K3BA 4A5YA 4PJNA 4GKRA 3ZFCA 1VOMA 2ZFMA 4FRZA 1D0YA 3CJOA 3LREA 2GM1A 3X2TA 4H1GA 1V8JA 5LT3A 1G8XA 4BXNA 3HQDA 4BN2A 3ZCWA 2HEHA 1F9UA 2FMEA 1D1BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LVK A;  1CZ7 A;  3B6U A;  1N6M A;  4PJJ A;  4PJM A;  2ZFI A;  3WRD A;  4ANJ A;  3T0Q A;  3U06 A;  1VFX A;  2FKY A;  3KAR A;  1LKX A;  3DC4 A;  4A51 A;  1Q0B A;  2G1Q A;  2Y65 A;  4HNA K;  2OWM A;  3KIN A;  4AP0 A;  2GRY A;  1YRS A;  5HLE A;  1X88 A;  2UYI A;  1F9W A;  4DBQ A;  1BR1 A;  4ETP A;  2WOG A;  2X2R A;  4E7Z A;  1D0X A;  3K5E A;  4PFP A;  4ZHI A;  5LT0 A;  1MMN A;  1MMG A;  5GSZ A;  5LT2 A;  1D0Z A;  2XAE A;  3L1C A;  1D1C A;  2ZFJ A;  2X7C A;  2V26 A;  2X7E A;  1SDM A;  1MMA A;  1MMD A;  4AS7 A;  4BBG A;  4E7S A;  1F9V A;  4PJL A;  2NCD A;  2X51 A;  3B6V A;  4A28 A;  2ZFK A;  1VFW A;  3KEN A;  4PK4 A;  1FMV A;  4ZCA A;  2ZFL A;  1V8K A;  1MKJ A;  3NWN A;  3WPN A;  2VB6 A;  2Y5W A;  3DCB A;  1VFZ A;  4A50 A;  4B7B A;  1T5C A;  3COB A;  3PXN A;  2FL2 A;  2VVG A;  4UBF A;  1F9T A;  2VAS A;  1BR4 A;  2Q2Z A;  1I5S A;  2Q2Y A;  1GOJ A;  1RY6 A;  2PG2 A;  1II6 A;  5LT4 A;  3BFN A;  2FL6 A;  1FMW A;  1I6I A;  2IEH A;  1VFV A;  4PFO A;  3ZFD A;  3CNZ A;  1MNE A;  4Y05 A;  1BR2 A;  4DBR A;  1KK7 A;  3GBJ A;  2UYM A;  2MYS A;  4LNU K;  5LT1 A;  2KIN A;  2X7D A;  4A14 A;  2XT3 A;  3L9H A;  3H4S A;  4A1Z A;  1D1A A;  1BG2 A;  3K3B A;  4A5Y A;  4PJN A;  4GKR A;  3ZFC A;  1VOM A;  2ZFM A;  4FRZ A;  1D0Y A;  3CJO A;  3LRE A;  2GM1 A;  3X2T A;  4H1G A;  1V8J A;  5LT3 A;  1G8X A;  4BXN A;  3HQD A;  4BN2 A;  3ZCW A;  2HEH A;  1F9U A;  2FME A;  1D1B A; 
#chains in the Genus database with same CATH topology
 1LVK A;  1CZ7 A;  3B6U A;  1N6M A;  4PJJ A;  4PJM A;  2ZFI A;  3WRD A;  4ANJ A;  3T0Q A;  3U06 A;  1VFX A;  2FKY A;  3KAR A;  1LKX A;  3DC4 A;  4A51 A;  1Q0B A;  2G1Q A;  2Y65 A;  4HNA K;  2OWM A;  3KIN A;  4AP0 A;  2GRY A;  1YRS A;  5HLE A;  1X88 A;  2UYI A;  1F9W A;  4DBQ A;  1BR1 A;  4ETP A;  2WOG A;  2X2R A;  4E7Z A;  1D0X A;  3K5E A;  4PFP A;  4ZHI A;  5LT0 A;  1MMN A;  1MMG A;  5GSZ A;  5LT2 A;  1D0Z A;  2XAE A;  3L1C A;  1D1C A;  2ZFJ A;  2X7C A;  2V26 A;  2X7E A;  1SDM A;  1MMA A;  1MMD A;  4AS7 A;  4BBG A;  4E7S A;  1F9V A;  4PJL A;  2NCD A;  2X51 A;  3B6V A;  4A28 A;  2ZFK A;  1VFW A;  3KEN A;  4PK4 A;  1FMV A;  4ZCA A;  2ZFL A;  1V8K A;  1MKJ A;  3NWN A;  3WPN A;  2VB6 A;  2Y5W A;  3DCB A;  1VFZ A;  4A50 A;  4B7B A;  1T5C A;  3COB A;  3PXN A;  2FL2 A;  2VVG A;  4GKP A;  4UBF A;  1F9T A;  2VAS A;  1BR4 A;  2Q2Z A;  1I5S A;  2Q2Y A;  1GOJ A;  1RY6 A;  2PG2 A;  1II6 A;  5LT4 A;  3BFN A;  2FL6 A;  1FMW A;  1I6I A;  2IEH A;  1VFV A;  2O0A A;  4PFO A;  3ZFD A;  3CNZ A;  1MNE A;  4Y05 A;  1BR2 A;  4DBR A;  1KK7 A;  3GBJ A;  2UYM A;  2MYS A;  4LNU K;  5LT1 A;  4GKQ A;  2KIN A;  2X7D A;  4ETP B;  4A14 A;  2XT3 A;  3L9H A;  3H4S A;  4A1Z A;  1D1A A;  1BG2 A;  3K3B A;  4A5Y A;  4PJN A;  4GKR A;  3ZFC A;  1VOM A;  2ZFM A;  4FRZ A;  1D0Y A;  3CJO A;  3LRE A;  2GM1 A;  3X2T A;  4H1G A;  1V8J A;  5LT3 A;  1G8X A;  4BXN A;  3HQD A;  4BN2 A;  3ZCW A;  2HEH A;  1F9U A;  2FME A;  1D1B A; 
#chains in the Genus database with same CATH homology
 1LVK A;  1CZ7 A;  3B6U A;  1N6M A;  4PJJ A;  4PJM A;  2ZFI A;  3WRD A;  4ANJ A;  3T0Q A;  3U06 A;  1VFX A;  2FKY A;  3KAR A;  1LKX A;  3DC4 A;  4A51 A;  1Q0B A;  2G1Q A;  2Y65 A;  4HNA K;  2OWM A;  3KIN A;  4AP0 A;  2GRY A;  1YRS A;  5HLE A;  1X88 A;  2UYI A;  1F9W A;  4DBQ A;  1BR1 A;  4ETP A;  2WOG A;  2X2R A;  4E7Z A;  1D0X A;  3K5E A;  4PFP A;  4ZHI A;  5LT0 A;  1MMN A;  1MMG A;  5GSZ A;  5LT2 A;  1D0Z A;  2XAE A;  3L1C A;  1D1C A;  2ZFJ A;  2X7C A;  2V26 A;  2X7E A;  1SDM A;  1MMA A;  1MMD A;  4AS7 A;  4BBG A;  4E7S A;  1F9V A;  4PJL A;  2NCD A;  2X51 A;  3B6V A;  4A28 A;  2ZFK A;  1VFW A;  3KEN A;  4PK4 A;  1FMV A;  4ZCA A;  2ZFL A;  1V8K A;  1MKJ A;  3NWN A;  3WPN A;  2VB6 A;  2Y5W A;  3DCB A;  1VFZ A;  4A50 A;  4B7B A;  1T5C A;  3COB A;  3PXN A;  2FL2 A;  2VVG A;  4UBF A;  1F9T A;  2VAS A;  1BR4 A;  2Q2Z A;  1I5S A;  2Q2Y A;  1GOJ A;  1RY6 A;  2PG2 A;  1II6 A;  5LT4 A;  3BFN A;  2FL6 A;  1FMW A;  1I6I A;  2IEH A;  1VFV A;  4PFO A;  3ZFD A;  3CNZ A;  1MNE A;  4Y05 A;  1BR2 A;  4DBR A;  1KK7 A;  3GBJ A;  2UYM A;  2MYS A;  4LNU K;  5LT1 A;  2KIN A;  2X7D A;  4A14 A;  2XT3 A;  3L9H A;  3H4S A;  4A1Z A;  1D1A A;  1BG2 A;  3K3B A;  4A5Y A;  4PJN A;  4GKR A;  3ZFC A;  1VOM A;  2ZFM A;  4FRZ A;  1D0Y A;  3CJO A;  3LRE A;  2GM1 A;  3X2T A;  4H1G A;  1V8J A;  5LT3 A;  1G8X A;  4BXN A;  3HQD A;  4BN2 A;  3ZCW A;  2HEH A;  1F9U A;  2FME A;  1D1B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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